M Shane Hutson

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint Cell sorting in three dimensions: topology, fluctuations, and fluidlike instabilities
    M Shane Hutson
    Department of Physics, Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Station B 351807, Nashville, Tennessee 37235, USA
    Phys Rev Lett 101:148105. 2008
  2. ncbi request reprint Plasma and cavitation dynamics during pulsed laser microsurgery in vivo
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, VU Station B 351807, Nashville, Tennessee 37235 1807, USA
    Phys Rev Lett 99:158104. 2007
  3. doi request reprint Mechanical aspects of developmental biology: perspectives on growth and form in the (post)-genomic age. Preface
    M Shane Hutson
    Vanderbilt Institute for Integrative Biosystem Research and Education, Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA
    Phys Biol 5:015001. 2008
  4. pmc Combining laser microsurgery and finite element modeling to assess cell-level epithelial mechanics
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 97:3075-85. 2009
  5. ncbi request reprint Interplay of wavelength, fluence and spot-size in free-electron laser ablation of cornea
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA
    Opt Express 17:9840-50. 2009
  6. doi request reprint Probing embryonic tissue mechanics with laser hole drilling
    Xiaoyan Ma
    Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, TN 37235, USA
    Phys Biol 6:036004. 2009
  7. pmc Wavelength-dependent conformational changes in collagen after mid-infrared laser ablation of cornea
    Yaowu Xiao
    Department of Physics and Astronomy, Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, Tennessee 37235, USA
    Biophys J 94:1359-66. 2008
  8. pmc Cellular mechanics of germ band retraction in Drosophila
    Holley E Lynch
    Department of Physics and Astronomy, VU Station B 351807, Vanderbilt University, Nashville, TN, USA
    Dev Biol 384:205-13. 2013
  9. pmc Wavelength-dependent collagen fragmentation during mid-IR laser ablation
    Yaowu Xiao
    Department of Physics and Astronomy and Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 91:1424-32. 2006
  10. pmc Apical oscillations in amnioserosa cells: basolateral coupling and mechanical autonomy
    Aroshan K Jayasinghe
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 105:255-65. 2013

Collaborators

  • G W Brodland
  • Kevin Parker
  • Peng Zhang
  • Daniel P Kiehart
  • Holley E Lynch
  • Yaowu Xiao
  • David N Mashburn
  • Xiaoyan Ma
  • Aroshan K Jayasinghe
  • Sarah M Crews
  • Mingsheng Guo
  • Glenn S Edwards
  • Brett Rosenthal
  • Robert Gish
  • Elliott Kim
  • Karl Echiverri
  • Peter C Scully
  • Prasad L Polavarapu
  • Ganesh Shanmugam

Detail Information

Publications15

  1. ncbi request reprint Cell sorting in three dimensions: topology, fluctuations, and fluidlike instabilities
    M Shane Hutson
    Department of Physics, Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Station B 351807, Nashville, Tennessee 37235, USA
    Phys Rev Lett 101:148105. 2008
    ..It occurs by a Plateau-Rayleigh instability of cell threads-deterministically driven by high tension. At high minority-cell fractions, untangling dominates and significant partial sorting can occur without fluctuations...
  2. ncbi request reprint Plasma and cavitation dynamics during pulsed laser microsurgery in vivo
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, VU Station B 351807, Nashville, Tennessee 37235 1807, USA
    Phys Rev Lett 99:158104. 2007
    ..Second, the biological matrix constrains the growth of laser-induced cavitation bubbles. Both effects reduce the disrupted region in vivo when compared to extrapolations from measurements in water...
  3. doi request reprint Mechanical aspects of developmental biology: perspectives on growth and form in the (post)-genomic age. Preface
    M Shane Hutson
    Vanderbilt Institute for Integrative Biosystem Research and Education, Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA
    Phys Biol 5:015001. 2008
    ..This paper focuses on the mechanical aspects of morphogenesis-highlighting those areas where mechanics and molecular genetics are converging toward a much-needed synthesis...
  4. pmc Combining laser microsurgery and finite element modeling to assess cell-level epithelial mechanics
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 97:3075-85. 2009
    ..The mesh also reproduces a number of double-wounding experiments in which successive holes are drilled in a single cell...
  5. ncbi request reprint Interplay of wavelength, fluence and spot-size in free-electron laser ablation of cornea
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA
    Opt Express 17:9840-50. 2009
    ..Plume imaging at several wavelengths and spot sizes suggests that this effect is due to increased post-pulse ablation at larger spots...
  6. doi request reprint Probing embryonic tissue mechanics with laser hole drilling
    Xiaoyan Ma
    Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, TN 37235, USA
    Phys Biol 6:036004. 2009
    ..We use the site and stage dependence of the recoil kinetics to constrain how the cellular mechanics change during closure. We apply these results to test extant computational models...
  7. pmc Wavelength-dependent conformational changes in collagen after mid-infrared laser ablation of cornea
    Yaowu Xiao
    Department of Physics and Astronomy, Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, Tennessee 37235, USA
    Biophys J 94:1359-66. 2008
    ..45-microm debris. These results support the hypothesis that the favorable ablative properties of protein-targeting wavelengths rest on selective heating of tissue proteins...
  8. pmc Cellular mechanics of germ band retraction in Drosophila
    Holley E Lynch
    Department of Physics and Astronomy, VU Station B 351807, Vanderbilt University, Nashville, TN, USA
    Dev Biol 384:205-13. 2013
    ..We conclude that the amnioserosa must play a key, but assistive, mechanical role that aids uncurling of the germ band. ..
  9. pmc Wavelength-dependent collagen fragmentation during mid-IR laser ablation
    Yaowu Xiao
    Department of Physics and Astronomy and Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 91:1424-32. 2006
    ..Identifying this transition is a key step toward understanding the observed wavelength-dependence of collateral damage in mid-infrared laser ablation...
  10. pmc Apical oscillations in amnioserosa cells: basolateral coupling and mechanical autonomy
    Aroshan K Jayasinghe
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 105:255-65. 2013
    ..All of the above require significant changes to existing computational models...
  11. pmc Enabling user-guided segmentation and tracking of surface-labeled cells in time-lapse image sets of living tissues
    David N Mashburn
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee 37235, USA
    Cytometry A 81:409-18. 2012
    ....
  12. ncbi request reprint Forces for morphogenesis investigated with laser microsurgery and quantitative modeling
    M Shane Hutson
    Department of Physics and Free Electron Laser Laboratory, Duke University, Durham, NC 27708, USA
    Science 300:145-9. 2003
    ....
  13. ncbi request reprint Advantage of the Mark-III FEL for biophysical research and biomedical applications
    Glenn S Edwards
    Duke University Free Electron Laser Laboratory, Durham, NC 27708, USA
    J Synchrotron Radiat 10:354-7. 2003
    ..At other wavelengths, collateral damage may be minimized within the sweet-spot, but the maximum intensities and pulse widths in these regions are insufficient to remove tissue at surgically relevant rates...