M Shane Hutson

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi Cell sorting in three dimensions: topology, fluctuations, and fluidlike instabilities
    M Shane Hutson
    Department of Physics, Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Station B 351807, Nashville, Tennessee 37235, USA
    Phys Rev Lett 101:148105. 2008
  2. ncbi Mechanical aspects of developmental biology: perspectives on growth and form in the (post)-genomic age. Preface
    M Shane Hutson
    Vanderbilt Institute for Integrative Biosystem Research and Education, Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA
    Phys Biol 5:015001. 2008
  3. ncbi Combining laser microsurgery and finite element modeling to assess cell-level epithelial mechanics
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 97:3075-85. 2009
  4. ncbi Plasma and cavitation dynamics during pulsed laser microsurgery in vivo
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, VU Station B 351807, Nashville, Tennessee 37235 1807, USA
    Phys Rev Lett 99:158104. 2007
  5. ncbi Interplay of wavelength, fluence and spot-size in free-electron laser ablation of cornea
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA
    Opt Express 17:9840-50. 2009
  6. ncbi Wavelength-dependent conformational changes in collagen after mid-infrared laser ablation of cornea
    Yaowu Xiao
    Department of Physics and Astronomy, Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, Tennessee 37235, USA
    Biophys J 94:1359-66. 2008
  7. ncbi Probing embryonic tissue mechanics with laser hole drilling
    Xiaoyan Ma
    Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, TN 37235, USA
    Phys Biol 6:036004. 2009
  8. ncbi Wavelength-dependent collagen fragmentation during mid-IR laser ablation
    Yaowu Xiao
    Department of Physics and Astronomy and Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 91:1424-32. 2006
  9. ncbi Enabling user-guided segmentation and tracking of surface-labeled cells in time-lapse image sets of living tissues
    David N Mashburn
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee 37235, USA
    Cytometry A 81:409-18. 2012
  10. ncbi Forces for morphogenesis investigated with laser microsurgery and quantitative modeling
    M Shane Hutson
    Department of Physics and Free Electron Laser Laboratory, Duke University, Durham, NC 27708, USA
    Science 300:145-9. 2003

Collaborators

Detail Information

Publications11

  1. ncbi Cell sorting in three dimensions: topology, fluctuations, and fluidlike instabilities
    M Shane Hutson
    Department of Physics, Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Station B 351807, Nashville, Tennessee 37235, USA
    Phys Rev Lett 101:148105. 2008
    ..It occurs by a Plateau-Rayleigh instability of cell threads-deterministically driven by high tension. At high minority-cell fractions, untangling dominates and significant partial sorting can occur without fluctuations...
  2. ncbi Mechanical aspects of developmental biology: perspectives on growth and form in the (post)-genomic age. Preface
    M Shane Hutson
    Vanderbilt Institute for Integrative Biosystem Research and Education, Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA
    Phys Biol 5:015001. 2008
    ..This paper focuses on the mechanical aspects of morphogenesis-highlighting those areas where mechanics and molecular genetics are converging toward a much-needed synthesis...
  3. ncbi Combining laser microsurgery and finite element modeling to assess cell-level epithelial mechanics
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 97:3075-85. 2009
    ..The mesh also reproduces a number of double-wounding experiments in which successive holes are drilled in a single cell...
  4. ncbi Plasma and cavitation dynamics during pulsed laser microsurgery in vivo
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, VU Station B 351807, Nashville, Tennessee 37235 1807, USA
    Phys Rev Lett 99:158104. 2007
    ..Second, the biological matrix constrains the growth of laser-induced cavitation bubbles. Both effects reduce the disrupted region in vivo when compared to extrapolations from measurements in water...
  5. ncbi Interplay of wavelength, fluence and spot-size in free-electron laser ablation of cornea
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA
    Opt Express 17:9840-50. 2009
    ..Plume imaging at several wavelengths and spot sizes suggests that this effect is due to increased post-pulse ablation at larger spots...
  6. ncbi Wavelength-dependent conformational changes in collagen after mid-infrared laser ablation of cornea
    Yaowu Xiao
    Department of Physics and Astronomy, Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, Tennessee 37235, USA
    Biophys J 94:1359-66. 2008
    ..45-microm debris. These results support the hypothesis that the favorable ablative properties of protein-targeting wavelengths rest on selective heating of tissue proteins...
  7. ncbi Probing embryonic tissue mechanics with laser hole drilling
    Xiaoyan Ma
    Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, TN 37235, USA
    Phys Biol 6:036004. 2009
    ..We use the site and stage dependence of the recoil kinetics to constrain how the cellular mechanics change during closure. We apply these results to test extant computational models...
  8. ncbi Wavelength-dependent collagen fragmentation during mid-IR laser ablation
    Yaowu Xiao
    Department of Physics and Astronomy and Vanderbilt Institute for Integrative Biosystem Research and Education, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 91:1424-32. 2006
    ..Identifying this transition is a key step toward understanding the observed wavelength-dependence of collateral damage in mid-infrared laser ablation...
  9. ncbi Enabling user-guided segmentation and tracking of surface-labeled cells in time-lapse image sets of living tissues
    David N Mashburn
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee 37235, USA
    Cytometry A 81:409-18. 2012
    ....
  10. ncbi Forces for morphogenesis investigated with laser microsurgery and quantitative modeling
    M Shane Hutson
    Department of Physics and Free Electron Laser Laboratory, Duke University, Durham, NC 27708, USA
    Science 300:145-9. 2003
    ....
  11. ncbi Advantage of the Mark-III FEL for biophysical research and biomedical applications
    Glenn S Edwards
    Duke University Free Electron Laser Laboratory, Durham, NC 27708, USA
    J Synchrotron Radiat 10:354-7. 2003
    ..At other wavelengths, collateral damage may be minimized within the sweet-spot, but the maximum intensities and pulse widths in these regions are insufficient to remove tissue at surgically relevant rates...