Haydar Frangoul

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature
    Katherine A Minson
    Department of Pediatrics, Monroe Carell Jr Children s Hospital at Vanderbilt, Nashville, TN 37232, USA
    Case Report Hematol 2013:563291. 2013
  2. doi request reprint Long-term follow-up and management guidelines in pediatric patients after allogenic hematopoietic stem cell transplantation
    Haydar Frangoul
    Pediatric Stem Cell Transplant and Pediatric Endocrinology, Vanderbilt University, Nashville, TN 37232 2573, USA
    Semin Hematol 49:94-103. 2012
  3. doi request reprint Unrelated bone marrow transplant for congenital amegakaryocytic thrombocytopenia: report of two cases and review of the literature
    Haydar Frangoul
    Pediatric Hematology Oncology, Vanderbilt University, Nashville, TN 37232 6310, USA
    Pediatr Transplant 14:E42-5. 2010
  4. doi request reprint Unrelated umbilical cord blood transplantation in children with immune deficiency: results of a multicenter study
    H Frangoul
    Pediatric Stem Cell Transplant Program, Vanderbilt University, Nashville, TN, USA
    Bone Marrow Transplant 45:283-8. 2010
  5. ncbi request reprint Acyclovir-resistant herpes simplex virus pneumonia post-unrelated stem cell transplantation: a word of caution
    Haydar Frangoul
    Pediatric Stem Cell Transplant Program, Vanderbilt Children s Hospital, Nashville, TN 37232, USA
    Pediatr Transplant 11:942-4. 2007
  6. doi request reprint Preengraftment syndrome after unrelated cord blood transplant is a strong predictor of acute and chronic graft-versus-host disease
    Haydar Frangoul
    Pediatric Stem Cell Transplant Program, Vanderbilt University, Nashville, Tennessee 37232 2573, USA
    Biol Blood Marrow Transplant 15:1485-8. 2009
  7. ncbi request reprint A prospective study of G-CSF primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium (PBMTC) study
    Haydar Frangoul
    Department of Pediatrics, Vanderbilt University, Nashville, TN 37232 2573, USA
    Blood 110:4584-7. 2007
  8. pmc Comparison of pre-cryopreserved and post-thaw-and-wash-nucleated cell count on major outcomes following unrelated cord blood transplant in children
    Meghann Pine McManus
    Pediatric Stem Cell Transplant Program, Primary Children s Medical Center, Salt Lake City, UT, USA
    Pediatr Transplant 16:438-42. 2012
  9. doi request reprint Incidence, risk factors, and outcome of pneumatosis intestinalis in pediatric stem cell transplant recipients
    Katrina Korhonen
    Pediatric Stem Cell Transplant Program, Monroe Carell Jr Children s Hospital at Vanderbilt, Nashville, Tennessee, USA
    Pediatr Blood Cancer 58:616-20. 2012
  10. doi request reprint Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma
    Michael J Eckrich
    Division of Pediatric Hematology Oncology, Vanderbilt University, Nashville, Tennessee 37232 6310, USA
    Pediatr Blood Cancer 53:1327-8. 2009

Collaborators

Detail Information

Publications29

  1. pmc t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature
    Katherine A Minson
    Department of Pediatrics, Monroe Carell Jr Children s Hospital at Vanderbilt, Nashville, TN 37232, USA
    Case Report Hematol 2013:563291. 2013
    ..This translocation has been associated with hypercalcemia, coagulopathy, and poor outcome. We present three cases of ALL with t(17;19) treated at our institution and review the outcome of children reported in the medical literature...
  2. doi request reprint Long-term follow-up and management guidelines in pediatric patients after allogenic hematopoietic stem cell transplantation
    Haydar Frangoul
    Pediatric Stem Cell Transplant and Pediatric Endocrinology, Vanderbilt University, Nashville, TN 37232 2573, USA
    Semin Hematol 49:94-103. 2012
    ..Each of these developmental stages has different sensitivities to treatment and can result in different sets of complications. We summarize the long-term side effects of allogeneic HSCT in children...
  3. doi request reprint Unrelated bone marrow transplant for congenital amegakaryocytic thrombocytopenia: report of two cases and review of the literature
    Haydar Frangoul
    Pediatric Hematology Oncology, Vanderbilt University, Nashville, TN 37232 6310, USA
    Pediatr Transplant 14:E42-5. 2010
    ..Both patients tolerated the transplant with minimal toxicity and durable engraftment. We also present a comprehensive review of the literature for unrelated donor transplant for this condition...
  4. doi request reprint Unrelated umbilical cord blood transplantation in children with immune deficiency: results of a multicenter study
    H Frangoul
    Pediatric Stem Cell Transplant Program, Vanderbilt University, Nashville, TN, USA
    Bone Marrow Transplant 45:283-8. 2010
    ..The probability of survival at 180 days and 1 year was 66.7% (95% CI: 44.3-81.7%) and 62.5% (95% CI: 40.3-78.4%), respectively. Unrelated CBT should be considered in children with PID...
  5. ncbi request reprint Acyclovir-resistant herpes simplex virus pneumonia post-unrelated stem cell transplantation: a word of caution
    Haydar Frangoul
    Pediatric Stem Cell Transplant Program, Vanderbilt Children s Hospital, Nashville, TN 37232, USA
    Pediatr Transplant 11:942-4. 2007
    ..Despite the in vitro sensitivity of the HSV isolates to foscarnet, both patients failed to respond to foscarnet therapy. Other antiviral therapies should be considered in those patients who fail to show rapid clinical improvement...
  6. doi request reprint Preengraftment syndrome after unrelated cord blood transplant is a strong predictor of acute and chronic graft-versus-host disease
    Haydar Frangoul
    Pediatric Stem Cell Transplant Program, Vanderbilt University, Nashville, Tennessee 37232 2573, USA
    Biol Blood Marrow Transplant 15:1485-8. 2009
    ..38). We conclude that PES is common following CB transplant (CBT) and additional more intensive immune suppression might be considered to decrease the risk of developing aGVHD and cGVHD...
  7. ncbi request reprint A prospective study of G-CSF primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium (PBMTC) study
    Haydar Frangoul
    Department of Pediatrics, Vanderbilt University, Nashville, TN 37232 2573, USA
    Blood 110:4584-7. 2007
    ..Collection of G-BM from pediatric donors is safe, and can result in high NC and CD34 cell doses that facilitate engraftment after myeloablative BMT without a discernable increase in the risk of GVHD...
  8. pmc Comparison of pre-cryopreserved and post-thaw-and-wash-nucleated cell count on major outcomes following unrelated cord blood transplant in children
    Meghann Pine McManus
    Pediatric Stem Cell Transplant Program, Primary Children s Medical Center, Salt Lake City, UT, USA
    Pediatr Transplant 16:438-42. 2012
    ..5 × 10(7) /kg (p = 0.039). In conclusion, receiving a PTW TNC of <2.5 × 10(7) /kg resulted in worse neutrophil engraftment and increased transplant-related mortality compared to a PTW TNC of ≥2.5 × 10(7) /kg...
  9. doi request reprint Incidence, risk factors, and outcome of pneumatosis intestinalis in pediatric stem cell transplant recipients
    Katrina Korhonen
    Pediatric Stem Cell Transplant Program, Monroe Carell Jr Children s Hospital at Vanderbilt, Nashville, Tennessee, USA
    Pediatr Blood Cancer 58:616-20. 2012
    ..Pneumatosis Intestinalis (PI) is a rare complication following hematopoietic stem cell transplant (HSCT). We sought to assess the incidence, risk factors, and outcome associated with PI...
  10. doi request reprint Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma
    Michael J Eckrich
    Division of Pediatric Hematology Oncology, Vanderbilt University, Nashville, Tennessee 37232 6310, USA
    Pediatr Blood Cancer 53:1327-8. 2009
    ..We report on a child with DS and relapsed Hodgkin disease who was successfully treated with high-dose chemotherapy and autologous stem cell transplant...
  11. doi request reprint A unique clinical presentation of X-linked lymphoproliferative syndrome with a novel mutation in SH2D1A and review of the literature
    Michael J Eckrich
    Department of Pediatrics, Division of Hematology Oncology, Vanderbilt University, School of Medicine, USA
    J Pediatr Hematol Oncol 33:e39-42. 2011
    ..We describe a patient with a novel missense mutation in SH2D1A. We report on his unique presentation, clinical course and subsequent successful treatment with a matched unrelated donor bone marrow transplant...
  12. doi request reprint New allergies after cord blood transplantation
    Leigh Ann Vaughan
    Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Cytotherapy 15:1259-65. 2013
    ..Late effects of CBT are not well described in the literature. In the present study, we present our experience of new-onset allergies in long-term survivors after CBT...
  13. doi request reprint A case of pediatric PTLD following autologous stem cell transplantation and review of the literature
    Michael J Eckrich
    Pediatric Hematology Oncology, Monroe Carell Jr Children s Hospital at Vanderbilt, Nashville, TN, USA
    Pediatr Transplant 16:E15-8. 2012
    ..He was successfully treated with cyclophosphamide, prednisone and rituximab. We also present a comprehensive review of the literature of PTLD in pediatric patients following ASCT...
  14. doi request reprint Unrelated stem cell transplant for infantile idiopathic myelofibrosis
    Jennifer Domm
    Pediatric Hematology Oncology, Vanderbilt University, Nashville, Tennessee 37232 6310, USA
    Pediatr Blood Cancer 52:893-5. 2009
    ..Both patients underwent unrelated stem cell transplant with complete resolution of their hematologic manifestations and resolution of the bone marrow fibrosis...
  15. pmc Heart transplant survival outcomes for adriamycin-dilated cardiomyopathy
    Andrew J Lenneman
    Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Am J Cardiol 111:609-12. 2013
    ..The temporal trends demonstrated that DCA remains a significant problem for cancer survivors...
  16. doi request reprint Severe ehrlichia infection in pediatric oncology and stem cell transplant patients
    Adam Esbenshade
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    Pediatr Blood Cancer 54:776-8. 2010
    ..These cases emphasize the need for a high index of suspicion for tickborne illness in oncology patients, and the importance of a low threshold for starting empiric treatment before confirming the diagnosis...
  17. doi request reprint Early lymphocyte reconstitution is associated with improved transplant outcome after cord blood transplantation
    Sara K Tedeschi
    Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, TN 37232 5505, USA
    Cytotherapy 13:78-82. 2011
    ..No consistent association has been reported between lymphocyte recovery and transplant outcome after cord blood transplantation (CBT)...
  18. doi request reprint Castleman disease in a pediatric liver transplant recipient: a case report and literature review
    Hugo J R Bonatti
    Department of Surgery Pathology Pediatrics, Vanderbilt University Medical Center, Vanderbilt, Nashville, TN, USA
    Pediatr Transplant 16:E229-34. 2012
    ..Castleman disease is a potential complication of solid organ transplant and HHV-8 infection. Reduction in immunosuppression and switch to sirolimus may be an effective strategy to treat this condition...
  19. pmc Compound heterozygous c-Mpl mutations in a child with congenital amegakaryocytic thrombocytopenia: functional characterization and a review of the literature
    Norma E Fox
    Department of Pediatrics, University of California, San Diego, La Jolla, CA 92017, USA
    Exp Hematol 37:495-503. 2009
    ..To genetically and functionally characterize mutations of c-Mpl that lead to thrombocytopenia in a child with congenital amegakaryocytic thrombocytopenia...
  20. ncbi request reprint Incidence and outcome of chronic graft-versus-host disease using National Institutes of Health consensus criteria
    Madan Jagasia
    Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Biol Blood Marrow Transplant 13:1207-15. 2007
    ..36, P = .0144) were significant independent predictors of survival. The OS with different NIH subtypes of GVHD after day 100 from SCT varies, and is superior for patients with classic cGVHD...
  21. doi request reprint Initial vancomycin dosing in pediatric oncology and stem cell transplant patients
    Christina C Piro
    Department of Pharmacy, Vanderbilt Children s Hospital, Nashville, TN, USA
    J Pediatr Hematol Oncol 31:3-7. 2009
    ..Gram-positive bacteremia is a common infection in pediatric oncology and stem cell transplant (SCT) patients requiring therapy with vancomycin. Optimal dosing of vancomycin in this patient population has not been well established...
  22. doi request reprint Direct provider feedback to decrease chemotherapy ordering errors: the "gray envelope" initiative
    Katie Bruce
    Department of Pharmacy, Monroe Carell Jr Children s Hospital at Vanderbilt, Nashville, TN 37232 6310, USA
    Pediatr Blood Cancer 59:1330-1. 2012
    ..9% post intervention (P < 0.001). We conclude that direct written provider feedback can result in a significant decrease in chemotherapy ordering errors...
  23. ncbi request reprint Mobilization of Ph chromosome-negative peripheral blood stem cells in a child with chronic myeloid leukemia after imatinib-induced complete molecular remission
    Wendy Woods-Swafford
    Department of Pediatric Hematology Oncology, Stem Cell Transplant, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Pediatr Blood Cancer 50:639-41. 2008
    ..We describe a child who achieved molecular remission with imatinib mesylate. BCR-ABL negative peripheral blood stem cells (PBSC) were successfully collected after mobilization with filgrastim...
  24. pmc Schimke Immunoosseous Dysplasia associated with undifferentiated carcinoma and a novel SMARCAL1 mutation in a child
    Clinton Carroll
    Division of Pediatric Hematology Oncology, Monroe Carell Jr Children s Hospital, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 6310, USA
    Pediatr Blood Cancer 60:E88-90. 2013
    ..We report a child with SIOD and a novel S859P missense mutation in SMARCAL1 who developed undifferentiated carcinoma of the sinus...
  25. ncbi request reprint Allogeneic bone marrow transplantation for chemotherapy-refractory hepatosplenic gammadelta T-cell lymphoma: case report and review of the literature
    Jennifer Ann Domm
    Division of Pediatric Hematology Oncology, Department of Pathology, Vanderbilt University, Nashville, TN 37232, USA
    J Pediatr Hematol Oncol 27:607-10. 2005
    ..She is currently alive and has remained in remission for 30 months after transplantation. The authors also review the literature for similar pediatric cases...
  26. ncbi request reprint A cord blood transplant recipient with Mycobacterium mucogenicum central venous catheter infection after infusion of tap water
    Gregory A Fleming
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    Pediatr Infect Dis J 25:567-9. 2006
    ..The infection was successfully treated by removal of the central venous catheter and administration of antimicrobial therapy...
  27. ncbi request reprint Use of G-CSF in matched sibling donor pediatric allogeneic transplantation: a consensus statement from the Children's Oncology Group (COG) Transplant Discipline Committee and Pediatric Blood and Marrow Transplant Consortium (PBMTC) Executive Committee
    Stephan A Grupp
    Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 46:414-21. 2006
    ..We conclude that the approach is promising and warrants further study. Risks of G-CSF to the donor are minimal and benefits to both donor and recipient may occur...
  28. ncbi request reprint Busulfan/melphalan/antithymocyte globulin followed by unrelated donor cord blood transplantation for treatment of infant leukemia and leukemia in young children: the Cord Blood Transplantation study (COBLT) experience
    Donna A Wall
    Texas Transplant Institute, Southwest Texas Methodist Hospital, San Antonio, Texas 78229, USA
    Biol Blood Marrow Transplant 11:637-46. 2005
    ....
  29. ncbi request reprint A phase II multicenter study of visilizumab, humanized anti-CD3 antibody, to treat steroid-refractory acute graft-versus-host disease
    Paul A Carpenter
    Fred Hutchinson Cancer Research Center, Clinical Research Division, 1100 Fairview Ave N, Mailstop D5 290, Seattle, WA 98109, USA
    Biol Blood Marrow Transplant 11:465-71. 2005
    ..Survival at 180 days was 32% (95% confidence interval, 18%-46%). The administration of visilizumab as used in this study seems to be sufficiently safe and effective to warrant further assessment for treatment or prevention of GVHD...