J H Fowke

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint Head and neck cancer: a case for inhibition by isothiocyanates and indoles from cruciferous vegetables
    Jay H Fowke
    Division of Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
    Eur J Cancer Prev 16:348-56. 2007
  2. ncbi request reprint Association between prostate-specific antigen and leptin, adiponectin, HbA1c or C-peptide among African-American and Caucasian men
    J H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    Prostate Cancer Prostatic Dis 11:264-9. 2008
  3. pmc Colonoscopy screening in African Americans and Whites with affected first-degree relatives
    Harvey J Murff
    Vanderbilt Epidemiology Center, Nashville, TN 37203 1738, USA
    Arch Intern Med 168:625-31. 2008
  4. pmc Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study
    Megan D Fesinmeyer
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    BMC Med Genet 14:6. 2013
  5. pmc Association between physical activity, lower urinary tract symptoms (LUTS) and prostate volume
    Jay H Fowke
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    BJU Int 111:122-8. 2013
  6. pmc Association between biomarkers of obesity and risk of high-grade prostatic intraepithelial neoplasia and prostate cancer--evidence of effect modification by prostate size
    Jay H Fowke
    Vanderbilt University Medical Center, Division of Epidemiology, Nashville, TN 37203, United States
    Cancer Lett 328:345-52. 2013
  7. pmc Obesity, body composition, and prostate cancer
    Jay H Fowke
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    BMC Cancer 12:23. 2012
  8. pmc Race and socioeconomic status are independently associated with benign prostatic hyperplasia
    Jay H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
    J Urol 180:2091-6; discussion 2096. 2008
  9. pmc Association of nonsteroidal anti-inflammatory drugs, prostate specific antigen and prostate volume
    Jay H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
    J Urol 181:2064-70. 2009
  10. pmc PSA and body composition by dual X-ray absorptiometry (DXA) in NHANES
    Jay H Fowke
    Division of Epidemiology, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA
    Prostate 70:120-5. 2010

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Head and neck cancer: a case for inhibition by isothiocyanates and indoles from cruciferous vegetables
    Jay H Fowke
    Division of Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
    Eur J Cancer Prev 16:348-56. 2007
    ..Addressing these factors in a future intervention may define a low-cost and non-toxic approach to reduce the burden of head and neck cancer...
  2. ncbi request reprint Association between prostate-specific antigen and leptin, adiponectin, HbA1c or C-peptide among African-American and Caucasian men
    J H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    Prostate Cancer Prostatic Dis 11:264-9. 2008
    ..84, 0.73, 0.77 and 0.45 ng ml(-1) across quartiles of HbA1c, respectively; P(trend)=0.005). This may suggest that metabolic disturbances related to metabolic syndrome or diabetes affect the ability to detect early-stage prostate cancer...
  3. pmc Colonoscopy screening in African Americans and Whites with affected first-degree relatives
    Harvey J Murff
    Vanderbilt Epidemiology Center, Nashville, TN 37203 1738, USA
    Arch Intern Med 168:625-31. 2008
    ..Racial differences in colon cancer mortality could be related to variations in screening of increased-risk individuals...
  4. pmc Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study
    Megan D Fesinmeyer
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    BMC Med Genet 14:6. 2013
    ..Although smoking behavior is known to affect body mass index (BMI), the potential for smoking to influence genetic associations with BMI is largely unexplored...
  5. pmc Association between physical activity, lower urinary tract symptoms (LUTS) and prostate volume
    Jay H Fowke
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    BJU Int 111:122-8. 2013
    ..To determine the association between lower urinary tract symptoms (LUTS) severity and physical activity (PA) across workplace, home, and leisure domains. To determine the mediating role of prostate enlargement on LUTS severity and PA...
  6. pmc Association between biomarkers of obesity and risk of high-grade prostatic intraepithelial neoplasia and prostate cancer--evidence of effect modification by prostate size
    Jay H Fowke
    Vanderbilt University Medical Center, Division of Epidemiology, Nashville, TN 37203, United States
    Cancer Lett 328:345-52. 2013
    ..Our results suggest obesity advances prostate carcinogenesis, and that detection biases at prostate biopsy may explain past inconsistencies in the association between obesity and PC...
  7. pmc Obesity, body composition, and prostate cancer
    Jay H Fowke
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    BMC Cancer 12:23. 2012
    ....
  8. pmc Race and socioeconomic status are independently associated with benign prostatic hyperplasia
    Jay H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
    J Urol 180:2091-6; discussion 2096. 2008
    ..We investigated racial differences in and surgical intervention for benign prostatic hyperplasia in a large and predominantly low income population...
  9. pmc Association of nonsteroidal anti-inflammatory drugs, prostate specific antigen and prostate volume
    Jay H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
    J Urol 181:2064-70. 2009
    ....
  10. pmc PSA and body composition by dual X-ray absorptiometry (DXA) in NHANES
    Jay H Fowke
    Division of Epidemiology, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA
    Prostate 70:120-5. 2010
    ..Several studies also report that obese men have lower blood PSA levels, suggesting that obesity may be interfering with the ability to detect early-stage prostate cancer...
  11. pmc Racial differences in the association between body mass index and serum IGF1, IGF2, and IGFBP3
    Jay H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, Tennessee 37203 1738, USA
    Endocr Relat Cancer 17:51-60. 2010
    ..The effects of obesity throughout life on the IGF axis and racial differences in breast cancer risk require study...
  12. doi request reprint Issues in the design of molecular and genetic epidemiologic studies
    Jay H Fowke
    Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN 34203 1783, USA
    J Prev Med Public Health 42:343-8. 2009
    ....
  13. pmc Urinary isothiocyanate levels and lung cancer risk among non-smoking women: a prospective investigation
    Jay H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN 37203 1738, United States
    Lung Cancer 73:18-24. 2011
    ..To separate the effect of these divergent mechanisms of action, we investigated the association between urinary ITC levels and lung cancer risk among non-smoking women...
  14. pmc The associations between statin use and prostate cancer screening, prostate size, high-grade prostatic intraepithelial neoplasia (PIN), and prostate cancer
    Jay H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, 2525 West End Ave 6th Floor, Suite 600, Nashville, TN 37203 1738, USA
    Cancer Causes Control 22:417-26. 2011
    ..We also describe the association between statin use and prostate cancer and high-grade prostatic intraepithelial neoplasia (PIN) before and after controlling for prostate cancer screening indices associated with statin use...
  15. pmc Association between socioeconomic status (SES) and lower urinary tract symptom (LUTS) severity among black and white men
    Jay H Fowke
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    J Gen Intern Med 26:1305-10. 2011
    ..A higher prevalence of moderate or severe lower urinary tract symptoms (LUTS) has been reported among African Americans, but the separate effects of race and socioeconomic status (SES) on LUTS severity are unclear...
  16. ncbi request reprint Prostate volume modifies the association between obesity and prostate cancer or high-grade prostatic intraepithelial neoplasia
    Jay H Fowke
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, 1215 21st Ave South, Nashville, TN 37232 8300, USA
    Cancer Causes Control 18:375-84. 2007
    ..01). In conclusion, prostate volume acts as a modifier, and BMI and WHR are significantly associated with prostate cancer or PIN, respectively, in the absence of biopsy sampling error derived from obesity-related prostate enlargement...
  17. ncbi request reprint Urinary estrogen metabolites and breast cancer: differential pattern of risk found with pre- versus post-treatment collection
    Jay H Fowke
    Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
    Steroids 68:65-72. 2003
    ..We investigated the association between the relative concentrations of these metabolites in urine (2-OHE/16-OHE) and breast cancer in a case-control study of Chinese women living in Shanghai...
  18. ncbi request reprint Oral contraceptive use and breast cancer risk: modification by NAD(P)H:quinone oxoreductase (NQO1) genetic polymorphisms
    Jay H Fowke
    Center for Health Services Research, Vanderbilt University Medical Center, 6110 Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:1308-15. 2004
    ..43-6.25; C/T or T/T OR 0.49, 95% CI 0.29-0.81; P for interaction < 0.01). Our results require confirmation but suggest that the OC and breast cancer association depends on the ability to invoke protection from catechol estrogens...
  19. ncbi request reprint Impact of season of food frequency questionnaire administration on dietary reporting
    Jay H Fowke
    Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
    Ann Epidemiol 14:778-85. 2004
    ..This study investigates the effect of season of FFQ administration, a proxy for the recent diet, on FFQ responses...
  20. ncbi request reprint Prostate cancer screening between low-income African-American and Caucasian men
    Jay H Fowke
    Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
    Urol Oncol 23:333-40. 2005
    ..We investigated racial differences in prostate cancer screening according to age and socioeconomic and demographic indices in a large and predominantly low-income population...
  21. ncbi request reprint Brassica vegetable consumption reduces urinary F2-isoprostane levels independent of micronutrient intake
    Jay H Fowke
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
    Carcinogenesis 27:2096-102. 2006
    ..Our results suggest that Brassica consumption reduces systemic oxidative stress independent of the vitamin and mineral content of these vegetables...
  22. ncbi request reprint Obesity and prostate cancer screening among African-American and Caucasian men
    Jay H Fowke
    Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
    Prostate 66:1371-80. 2006
    ..We investigated the relationship between obesity and PSA testing, and evaluated the role of prior diagnoses and disease screening on PSA testing patterns...
  23. ncbi request reprint Effects of obesity and height on prostate-specific antigen (PSA) and percentage of free PSA levels among African-American and Caucasian men
    Jay H Fowke
    Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Cancer 107:2361-7. 2006
    ..The association between body mass index (BMI) and height on PSA and percentage of free PSA (%fPSA) was investigated within AA and CA men without a prior prostate cancer diagnosis...
  24. ncbi request reprint Urinary isothiocyanate levels, brassica, and human breast cancer
    Jay H Fowke
    Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
    Cancer Res 63:3980-6. 2003
    ..In conclusion, greater Brassica vegetable consumption, as measured by the urinary ITC biomarker, was associated with significantly reduced breast cancer risk among Chinese women...
  25. ncbi request reprint Urinary excretion of dithiocarbamates and self-reported Cruciferous vegetable intake: application of the 'method of triads' to a food-specific biomarker
    Jay H Fowke
    Vanderbilt Ingram Cancer Center, Vanderbilt Center for Health Services Research, Nashville, TN 37232 8300, USA
    Public Health Nutr 5:791-9. 2002
    ..We compared urinary DTC levels to intake as measured by two self-reported dietary assessment techniques...
  26. ncbi request reprint The association between body size, prostate volume and prostate-specific antigen
    J H Fowke
    Vanderbilt Epidemiology Center, Division of Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
    Prostate Cancer Prostatic Dis 10:137-42. 2007
    ..These associations were less consistent among subjects diagnosed with high-grade prostatic intraepithelial neoplasia or cancer. Our data suggest that obesity and height are independently associated with prostate volume....
  27. ncbi request reprint Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk
    Sang Ah Lee
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA
    Am J Clin Nutr 87:753-60. 2008
    ..Cruciferous vegetables are the primary source of isothiocyanates and other glucosinolate derivatives that are known to induce phase II detoxifying enzymes, including glutathione S-transferases (GSTs)...
  28. ncbi request reprint Urinary isothiocyanate excretion, brassica consumption, and gene polymorphisms among women living in Shanghai, China
    Jay H Fowke
    Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 12:1536-9. 2003
    ..In conclusion, a single urinary ITC measure, in conjunction with markers of Phase II enzyme activity, provides a complementary measure of habitual Brassica intake among Shanghai women...
  29. doi request reprint The association of plasma fatty acids with prostate cancer risk in African Americans and Africans
    Flora A Ukoli
    Dept of Surgery, Meharry Medical College, Nashville, TN 37208, USA
    J Health Care Poor Underserved 21:127-47. 2010
    ..These preliminary findings need to be further explored in a larger study that will include risk analysis of fatty-acid ratios to clarify their combined impact on PCa risk...
  30. pmc Papanicolaou testing among women in the southern United States
    Neeraja B Peterson
    Institute for Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
    J Womens Health (Larchmt) 17:939-46. 2008
    ..We examined Pap testing among southern women, mostly of low income and educational status, to determine if rates were similar to those reported nationally and to examine which factors were related to receipt of Pap tests...
  31. ncbi request reprint Physical activity, body size, and estrogen metabolism in women
    Charles E Matthews
    Vanderbilt Ingram Cancer Center, Center for Health Services Research, Vanderbilt University Medical Center, Medical Center East, Suite 6100, Nashville, TN 37232 8300, USA
    Cancer Causes Control 15:473-81. 2004
    ..We examined these relationships in cross-sectional analyses of 157 North American and Chinese women...
  32. pmc Detection of pre-neoplastic and neoplastic prostate disease by MALDI profiling of urine
    Amosy E M'Koma
    Department of Urologic Surgery, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center Nashville, TN 37232, USA
    Biochem Biophys Res Commun 353:829-34. 2007
    ..2% sensitivity. Comparing PCa and HGPIN resulted in 80.8% specificity and 81.0% sensitivity. The high throughput, low-cost assay method developed is amenable for large patient numbers required for supporting biomarker identification...
  33. pmc Use of colonoscopy and flexible sigmoidoscopy among African Americans and whites in a low-income population
    Neeraja B Peterson
    Prev Chronic Dis 5:A28. 2008
  34. ncbi request reprint Urinary estrogen metabolites, prostate specific antigen, and body mass index among African-American men in South Carolina
    Jane Teas
    Arnold School of Public Health, University of South Carolina, 2221 Devine Street Room 230, Columbia, SC 29208, USA
    Cancer Detect Prev 29:494-500. 2005
    ..African-American (AA) men in South Carolina have among the highest prostate cancer rates in the world, and thus provide an ideal population in which to investigate this hypothesis...
  35. ncbi request reprint Re: North American white mitochondrial haplogroups in prostate and renal cancer
    Jeffrey A Canter
    J Urol 176:2308-9; author reply 2309. 2006