Vernat J Exil


Affiliation: Vanderbilt University
Country: USA


  1. request reprint
    Exil V, Roberts R, Sims H, McLaughlin J, Malkin R, Gardner C, et al. Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice. Circ Res. 2003;93:448-55 pubmed
  2. request reprint
    Exil V, Gardner C, Rottman J, Sims H, Bartelds B, Khuchua Z, et al. Abnormal mitochondrial bioenergetics and heart rate dysfunction in mice lacking very-long-chain acyl-CoA dehydrogenase. Am J Physiol Heart Circ Physiol. 2006;290:H1289-97 pubmed
    ..Our observations provide insights into the possible mechanisms of stress-induced death in human newborns with abnormal fat metabolism and elucidate targeting of specific substrates for particular metabolic needs. ..
  3. Exil V, Silva Avila D, Benedetto A, Exil E, Adams M, Au C, et al. Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans. PLoS ONE. 2010;5:e14228 pubmed publisher
    ..The data obtained from our experiments suggest that TMEM135 is part of a regulatory circuit that plays a critical role in the survival of VLCAD-deficient mice and perhaps in other mitochondrial genetic defects of fat metabolism as well. ..