Kevin Erreger

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Exendin-4 decreases amphetamine-induced locomotor activity
    Kevin Erreger
    Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA
    Physiol Behav 106:574-8. 2012
  2. pmc Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, GA 30322 3090, USA
    J Physiol 563:345-58. 2005
  3. ncbi request reprint Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, Georgia 30322, USA
    J Neurosci 25:7858-66. 2005
  4. pmc Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, GA 30322 3090, USA
    J Physiol 569:381-93. 2005
  5. ncbi request reprint Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, 5025 Rollins Research Center, 1510 Clifton Road, Atlanta GA 30322 3090, USA
    Mol Pharmacol 72:907-20. 2007
  6. pmc Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder
    Erica Bowton
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8548, USA
    J Neurosci 30:6048-57. 2010
  7. pmc Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block
    Shashank M Dravid
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Centre, 1510 Clifton Road, Atlanta, GA 30322 3090, USA
    J Physiol 581:107-28. 2007
  8. ncbi request reprint Conserved structural and functional control of N-methyl-D-aspartate receptor gating by transmembrane domain M3
    Hongjie Yuan
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, Georgia 30322 3090, USA
    J Biol Chem 280:29708-16. 2005
  9. pmc Zinc inhibition of rat NR1/NR2A N-methyl-D-aspartate receptors
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, GA 30322, USA
    J Physiol 586:763-78. 2008
  10. ncbi request reprint Glutamate receptor gating
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, Georgia 30322 3090, USA
    Crit Rev Neurobiol 16:187-224. 2004

Collaborators

Detail Information

Publications15

  1. pmc Exendin-4 decreases amphetamine-induced locomotor activity
    Kevin Erreger
    Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA
    Physiol Behav 106:574-8. 2012
    ..Our findings implicate GLP-1R signaling as a novel modulator of psychostimulant-induced behavior and therefore a potential therapeutic target for psychostimulant abuse...
  2. pmc Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, GA 30322 3090, USA
    J Physiol 563:345-58. 2005
    ..However, under high-frequency tetanic stimulation (100 Hz; > 100 ms) typically used to induce long-term potentiation (LTP), the charge transfer mediated by NR1/NR2A considerably exceeds that of NR1/NR2B...
  3. ncbi request reprint Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, Georgia 30322, USA
    J Neurosci 25:7858-66. 2005
    ....
  4. pmc Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, GA 30322 3090, USA
    J Physiol 569:381-93. 2005
    ....
  5. ncbi request reprint Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, 5025 Rollins Research Center, 1510 Clifton Road, Atlanta GA 30322 3090, USA
    Mol Pharmacol 72:907-20. 2007
    ....
  6. pmc Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder
    Erica Bowton
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8548, USA
    J Neurosci 30:6048-57. 2010
    ..These studies identify a signaling network downstream of D(2)R activation, normally constraining DA action at synapses, that may be altered by DAT mutation to impact risk for DA-related disorders...
  7. pmc Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block
    Shashank M Dravid
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Centre, 1510 Clifton Road, Atlanta, GA 30322 3090, USA
    J Physiol 581:107-28. 2007
    ..These data suggest a tight coupling between the proton sensor and the ion channel gate as well as unique subunit-specific mechanisms of channel block...
  8. ncbi request reprint Conserved structural and functional control of N-methyl-D-aspartate receptor gating by transmembrane domain M3
    Hongjie Yuan
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, Georgia 30322 3090, USA
    J Biol Chem 280:29708-16. 2005
    ..In summary, these data suggest that the SYTANLAAF motif within M3 is a conserved and critical determinant of channel gating in all NMDA receptors...
  9. pmc Zinc inhibition of rat NR1/NR2A N-methyl-D-aspartate receptors
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, GA 30322, USA
    J Physiol 586:763-78. 2008
    ..These data and analyses are consistent with Zn(2+)-mediated inhibition of NMDA receptors primarily reflecting enhancement of proton inhibition...
  10. ncbi request reprint Glutamate receptor gating
    Kevin Erreger
    Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, Georgia 30322 3090, USA
    Crit Rev Neurobiol 16:187-224. 2004
    ....
  11. ncbi request reprint PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein
    Peter J Hamilton
    1 Vanderbilt Brain Institute, Vanderbilt University School of Medicine, Nashville, Tennessee, USA 2 Neuroscience Program in Substance Abuse, Vanderbilt University School of Medicine, Nashville, Tennessee, USA 3
    Nat Chem Biol 10:582-9. 2014
    ..We present what is to our knowledge the first demonstration of how PIP2 interactions with a membrane protein can regulate the behaviors of complex organisms. ..
  12. pmc Currents in response to rapid concentration jumps of amphetamine uncover novel aspects of human dopamine transporter function
    Kevin Erreger
    Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232, USA
    J Neurosci 28:976-89. 2008
    ..The model provides a framework for interpreting perturbations of hDAT activity...
  13. pmc Structural arrangement of the intracellular Ca2+ binding domains of the cardiac Na+/Ca2+ exchanger (NCX1.1): effects of Ca2+ binding
    Mrinalini Dixit
    Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232, USA
    J Biol Chem 288:4194-207. 2013
    ..Additional measurements have shown that there are significant changes in the dynamics of the F-G loop region of CBD2 that merit further characterization with regard to their possible involvement in regulation of NCX1.1 activity...
  14. pmc Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux
    Francesca Binda
    Department of Molecular Physiology and Biophysics, Center for Molecular Neuroscience, Kennedy Centerfor Research on Human Development, Vanderbilt University, 7124 MRBIII, 465 21st Avenue S, Nashville, TN 37232, USA
    Mol Pharmacol 74:1101-8. 2008
    ..These data suggest that AMPH activation of CaMKII supports DAT/SYN1A association, resulting in a mode of DAT capable of DA efflux...
  15. pmc Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes
    Philip E Chen
    Centre for Neuroscience Research, Hugh Robson Building, University of Edinburgh, George Square, Edinburgh, UK
    J Physiol 586:227-45. 2008
    ....