MICHAEL E ENGEL

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. doi Proleukemic RUNX1 and CBFbeta mutations in the pathogenesis of acute leukemia
    MICHAEL E ENGEL
    Department of Pediatrics, Monroe Carell Jr Children s Hospital, Nashville, TN, USA
    Cancer Treat Res 145:127-47. 2010
  2. pmc Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification
    MICHAEL E ENGEL
    Department of Pediatrics, Division of Pediatric Hematology Oncology, Vanderbilt Univesity School of Medicine, 397 Preston Research Building, 2220 Pierce Avenue, Nashville, TN 37232 6310, USA
    Mol Cell Biol 30:1852-63. 2010
  3. pmc Mtg16/Eto2 contributes to murine T-cell development
    AUBREY HUNT
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Mol Cell Biol 31:2544-51. 2011

Research Grants

  1. MTG-16 Regulation by Phosphorylation
    Michael Engel; Fiscal Year: 2006

Collaborators

Detail Information

Publications3

  1. doi Proleukemic RUNX1 and CBFbeta mutations in the pathogenesis of acute leukemia
    MICHAEL E ENGEL
    Department of Pediatrics, Monroe Carell Jr Children s Hospital, Nashville, TN, USA
    Cancer Treat Res 145:127-47. 2010
    ..Here we present an overview of the structural features of RUNX1/CBFbeta and their derivatives, their roles in transcriptional control, and their contributions to normal and malignant hematopoiesis...
  2. pmc Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification
    MICHAEL E ENGEL
    Department of Pediatrics, Division of Pediatric Hematology Oncology, Vanderbilt Univesity School of Medicine, 397 Preston Research Building, 2220 Pierce Avenue, Nashville, TN 37232 6310, USA
    Mol Cell Biol 30:1852-63. 2010
    ..These data suggest that MTG16 interfaces with critical components of the Notch transcription complex to affect Notch-dependent lineage allocation in hematopoiesis...
  3. pmc Mtg16/Eto2 contributes to murine T-cell development
    AUBREY HUNT
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Mol Cell Biol 31:2544-51. 2011
    ..Thus, Mtg16 integrates the activities of signaling pathways and nuclear factors in the establishment of T-cell fate specification...

Research Grants2

  1. MTG-16 Regulation by Phosphorylation
    Michael Engel; Fiscal Year: 2006
    ..Ultimately, the goal is to ascertain the effect of specific phosphorylation events on growth, transformation and development. These data may have future therapeutic implications for diverse cancer types. ..