S Eguchi

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint Epidermal growth factor receptor is indispensable for c-Fos expression and protein synthesis by angiotensin II
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Eur J Pharmacol 376:203-6. 1999
  2. ncbi request reprint Signal transduction of angiotensin II type 1 receptor through receptor tyrosine kinase
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, 37232, Nashville, TN 37232, USA
    Regul Pept 91:13-20. 2000
  3. ncbi request reprint Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 276:7957-62. 2001
  4. ncbi request reprint Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 274:36843-51. 1999
  5. ncbi request reprint Cross-talk between angiotensin II receptors and the tyrosine kinases and phosphatases
    T Inagami
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0146, USA
    J Am Soc Nephrol 10:S57-61. 1999
  6. ncbi request reprint Unique regulation of c-Jun N-terminal kinase by PYK2/CAK-beta in angiotensin II-stimulated vascular smooth muscle cells
    G D Frank
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Biochem Biophys Res Commun 286:692-6. 2001
  7. ncbi request reprint Protein kinase C inhibits insulin-induced Akt activation in vascular smooth muscle cells
    E D Motley
    Department of Anatomy and Physiology, Meharry Medical College, Nashville, TN 37208, USA
    Cell Mol Biol (Noisy-le-grand) 47:1059-62. 2001
  8. ncbi request reprint Angiotensin II-mediated vascular smooth muscle cell growth signaling
    T Inagami
    Department of Biochemistry, Vanderbilt University, Nashville, TN 37232 0146, USA
    Braz J Med Biol Res 33:619-24. 2000
  9. ncbi request reprint Angiotensin receptors: molecular biology and signalling
    T Inagami
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Clin Exp Pharmacol Physiol 26:544-9. 1999
  10. ncbi request reprint Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodelling
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, U S A
    Biochem Soc Trans 31:1198-202. 2003

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Epidermal growth factor receptor is indispensable for c-Fos expression and protein synthesis by angiotensin II
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Eur J Pharmacol 376:203-6. 1999
    ....
  2. ncbi request reprint Signal transduction of angiotensin II type 1 receptor through receptor tyrosine kinase
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, 37232, Nashville, TN 37232, USA
    Regul Pept 91:13-20. 2000
    ..Whether the EGF receptor signal transduction induced by AngII plays an essential role in cardiovascular remodeling remains to be investigated...
  3. ncbi request reprint Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 276:7957-62. 2001
    ..From these data, we conclude that ERK and p38MAPK activation by AngII requires the metalloprotease-dependent EGF receptor transactivation, whereas the JNK activation is regulated without involvement of EGF receptor transactivation...
  4. ncbi request reprint Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 274:36843-51. 1999
    ....
  5. ncbi request reprint Cross-talk between angiotensin II receptors and the tyrosine kinases and phosphatases
    T Inagami
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0146, USA
    J Am Soc Nephrol 10:S57-61. 1999
    ..The relative importance of AT1 and AT2 receptor actions depends on the levels of AT1 and AT2 receptor expression...
  6. ncbi request reprint Unique regulation of c-Jun N-terminal kinase by PYK2/CAK-beta in angiotensin II-stimulated vascular smooth muscle cells
    G D Frank
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Biochem Biophys Res Commun 286:692-6. 2001
    ....
  7. ncbi request reprint Protein kinase C inhibits insulin-induced Akt activation in vascular smooth muscle cells
    E D Motley
    Department of Anatomy and Physiology, Meharry Medical College, Nashville, TN 37208, USA
    Cell Mol Biol (Noisy-le-grand) 47:1059-62. 2001
    ..From these data, we conclude that PKC is a potent negative regulator of the insulin signal in the vasculature, which indicate an important role of PKC in the development of insulin resistance in cardiovascular disease...
  8. ncbi request reprint Angiotensin II-mediated vascular smooth muscle cell growth signaling
    T Inagami
    Department of Biochemistry, Vanderbilt University, Nashville, TN 37232 0146, USA
    Braz J Med Biol Res 33:619-24. 2000
    ..These studies indicate a transactivation mechanism that utilizes EGFR as a bridge between a Gq-coupled receptor and activation of phosphotyrosine generation...
  9. ncbi request reprint Angiotensin receptors: molecular biology and signalling
    T Inagami
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Clin Exp Pharmacol Physiol 26:544-9. 1999
    ..5. Newer mechanisms and functions of these and other receptors will be clarified by the combination of molecular, cellular and integrated physiological studies...
  10. ncbi request reprint Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodelling
    S Eguchi
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, U S A
    Biochem Soc Trans 31:1198-202. 2003
    ....