Kathleen M Egan

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint Early life factors in relation to breast cancer risk in postmenopausal women
    Linda Titus-Ernstoff
    Norris Cotton Cancer Center and the Department of Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Cancer Epidemiol Biomarkers Prev 11:207-10. 2002
  2. ncbi request reprint MnSOD polymorphism and breast cancer in a population-based case-control study
    Kathleen M Egan
    Department of Medicine, Vanderbilt University Medical Center, Suite 6000 Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Lett 199:27-33. 2003
  3. ncbi request reprint Commentary: sunlight, vitamin D, and the cancer connection revisited
    Kathleen M Egan
    Vanderbilt Ingram Cancer Center, Health Services Research, Vanderbilt University, 6000 Medical Center East, Nashville, TN 37235, USA
    Int J Epidemiol 35:227-30. 2006
  4. ncbi request reprint STK15 polymorphism and breast cancer risk in a population-based study
    Kathleen M Egan
    Vanderbilt University Medical Center, Suite 6000, MCE, Nashville, TN 37232 8300, USA
    Carcinogenesis 25:2149-53. 2004
  5. ncbi request reprint Genetic polymorphisms in GSTM1, GSTP1, and GSTT1 and the risk for breast cancer: results from the Shanghai Breast Cancer Study and meta-analysis
    Kathleen M Egan
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 27232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:197-204. 2004
  6. pmc Association of COMT haplotypes and breast cancer risk in caucasian women
    Neeraja B Peterson
    Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Suite 6108 Medical Center East, North Tower, Nashville, TN 37232 8300, USA
    Anticancer Res 30:217-20. 2010
  7. ncbi request reprint Alcohol consumption and ovarian cancer risk in a population-based case-control study
    Neeraja B Peterson
    Center for Health Services Research, Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
    Int J Cancer 119:2423-7. 2006
  8. pmc Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women
    Hui Cai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Pharmacogenet Genomics 18:657-64. 2008
  9. ncbi request reprint Population-based case-control study of AhR (aryl hydrocarbon receptor) and CYP1A2 polymorphisms and breast cancer risk
    Ji Rong Long
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, Nashville, TN 37232, USA
    Pharmacogenet Genomics 16:237-43. 2006
  10. ncbi request reprint Whole-genome amplification of oral rinse self-collected DNA in a population-based case-control study of breast cancer
    Xueying Liang
    Center for Human Genetics Research and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Cancer Epidemiol Biomarkers Prev 16:1610-4. 2007

Detail Information

Publications48

  1. ncbi request reprint Early life factors in relation to breast cancer risk in postmenopausal women
    Linda Titus-Ernstoff
    Norris Cotton Cancer Center and the Department of Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Cancer Epidemiol Biomarkers Prev 11:207-10. 2002
    ..Overall, our results are consistent with previous studies and suggest that these early life factors have a modest influence on breast cancer risk in postmenopausal women...
  2. ncbi request reprint MnSOD polymorphism and breast cancer in a population-based case-control study
    Kathleen M Egan
    Department of Medicine, Vanderbilt University Medical Center, Suite 6000 Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Lett 199:27-33. 2003
    ..91-1.77) or two (RR: 1.18; 95% CI: 0.81-1.73) Ala alleles compared to those homozygous for the wild-type Val genotype. Results do not support any overall association of the Ala-9Val MnSOD polymorphism to the development of breast cancer...
  3. ncbi request reprint Commentary: sunlight, vitamin D, and the cancer connection revisited
    Kathleen M Egan
    Vanderbilt Ingram Cancer Center, Health Services Research, Vanderbilt University, 6000 Medical Center East, Nashville, TN 37235, USA
    Int J Epidemiol 35:227-30. 2006
  4. ncbi request reprint STK15 polymorphism and breast cancer risk in a population-based study
    Kathleen M Egan
    Vanderbilt University Medical Center, Suite 6000, MCE, Nashville, TN 37232 8300, USA
    Carcinogenesis 25:2149-53. 2004
    ..79). No interaction was detected between STK15 variants and estrogenic risk factors, although the power of these analyses was limited. These results suggest that STK15 may represent a low penetrance type breast cancer susceptibility gene...
  5. ncbi request reprint Genetic polymorphisms in GSTM1, GSTP1, and GSTT1 and the risk for breast cancer: results from the Shanghai Breast Cancer Study and meta-analysis
    Kathleen M Egan
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 27232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:197-204. 2004
    ....
  6. pmc Association of COMT haplotypes and breast cancer risk in caucasian women
    Neeraja B Peterson
    Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Suite 6108 Medical Center East, North Tower, Nashville, TN 37232 8300, USA
    Anticancer Res 30:217-20. 2010
    ..These results suggest that genetic variation in COMT has no significant association with breast cancer risk among Caucasian women...
  7. ncbi request reprint Alcohol consumption and ovarian cancer risk in a population-based case-control study
    Neeraja B Peterson
    Center for Health Services Research, Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
    Int J Cancer 119:2423-7. 2006
    ..30), though results for other subtypes were based on sparse data and results were imprecise. In this study, neither total alcohol consumption as a young adult nor recently was associated with an increase in the risk of ovarian cancer...
  8. pmc Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women
    Hui Cai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Pharmacogenet Genomics 18:657-64. 2008
    ..We investigated the associations of genetic polymorphisms in CYP19A1, a critical gene involved in estrogen synthesis, with plasma levels of sex hormones among postmenopausal Chinese women...
  9. ncbi request reprint Population-based case-control study of AhR (aryl hydrocarbon receptor) and CYP1A2 polymorphisms and breast cancer risk
    Ji Rong Long
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, Nashville, TN 37232, USA
    Pharmacogenet Genomics 16:237-43. 2006
    ....
  10. ncbi request reprint Whole-genome amplification of oral rinse self-collected DNA in a population-based case-control study of breast cancer
    Xueying Liang
    Center for Human Genetics Research and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Cancer Epidemiol Biomarkers Prev 16:1610-4. 2007
    ..Whole-genome amplification may introduce substantial allele amplification bias in gDNA collected using a common protocol in population-based epidemiologic studies...
  11. pmc Obesity, gynecological factors, and abnormal mammography follow-up in minority and medically underserved women
    Alecia Malin Fair
    Department of Surgery, Meharry Medical College, Nashville, Tennessee 37208, USA
    J Womens Health (Larchmt) 18:1033-9. 2009
    ....
  12. pmc Childbearing recency and modifiers of premenopausal breast cancer risk
    Neeraja B Peterson
    Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Suite 6108, Medical Center East, North Tower, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 17:3284-7. 2008
    ..90-2.04), adjusting for age and known breast cancer risk factors (Ptrend = 0.14). We did not find a significant interaction with breast-feeding (Pinteraction = 0.30) or pregnancy weight gain (Pinteraction = 0.09)...
  13. pmc A multistage genetic association study identifies breast cancer risk loci at 10q25 and 16q24
    Kathryn S Higginbotham
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Cancer Epidemiol Biomarkers Prev 21:1565-73. 2012
    ..We conducted a multistage genetic association study in a series of independent epidemiologic breast cancer study populations to identify novel breast cancer risk variants...
  14. pmc Psychosocial determinants of mammography follow-up after receipt of abnormal mammography results in medically underserved women
    Alecia Malin Fair
    Department of Surgery, Meharry Medical College, Nashville, TN 37208, USA
    J Health Care Poor Underserved 21:71-94. 2010
    ..0 vs. 5.3) (p-value<.01). These constructs have implications for understanding mammography follow-up among minority and medically underserved women. Further comprehensive study of these concepts is warranted...
  15. pmc Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of chinese, Japanese, and European ancestry
    Qiuyin Cai
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Cancer Res 71:1344-55. 2011
    ..This association may be explained in part by a putatively functional variant (rs6913578) identified in the region...
  16. pmc The "Got D'ViBE?" study: an inter-institutional project assessing vitamin D and mammographic breast density
    Toni J Lewis
    Department of Surgery, Meharry Medical College, Nashville, TN 37208, USA
    J Health Care Poor Underserved 21:17-25. 2010
    ..This effort resulted in techniques to measure vitamin D levels, breast density, and sunlight exposure. Outcomes from this collaboration may provide insight to researchers conducting similar investigations...
  17. ncbi request reprint Relation of anthropometric measurements to ovarian cancer risk in a population-based case-control study (United States)
    Neeraja B Peterson
    Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt University School of Medicine, Medical Center East, Suite 6000, Nashville, TN 37232 8300, USA
    Cancer Causes Control 17:459-67. 2006
    ..To examine the relationship between anthropometric measures and ovarian cancer by menopausal status...
  18. ncbi request reprint Prospective study of cigarette smoking and the risk of primary open-angle glaucoma
    Jae H Kang
    Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
    Arch Ophthalmol 121:1762-8. 2003
    ..To examine the association between cigarette smoking and incident primary open-angle glaucoma (POAG)...
  19. pmc Timing is everything: methodologic issues locating and recruiting medically underserved women for abnormal mammography follow-up research
    Alecia Malin Fair
    Department of Surgery, Meharry Medical College, 1005 Dr D B Todd Boulevard, Nashville, TN 37208, USA
    Contemp Clin Trials 29:537-46. 2008
    ..We present our experience attempting to locate and recruit minority and medically underserved women identified in a Nashville, Tennessee public hospital for a mammography follow-up study...
  20. ncbi request reprint Association of NAT2 and smoking in relation to breast cancer incidence in a population-based case-control study (United States)
    Kathleen M Egan
    Division of General Internal Medicine and the Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, 37232, USA
    Cancer Causes Control 14:43-51. 2003
    ..To evaluate the potential interaction between N-acetyltransferase 2 (NAT2) and smoking in breast cancer incidence...
  21. pmc A multistage association study identifies a breast cancer genetic locus at NCOA7
    Kathryn S P Higginbotham
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Cancer Res 71:3881-8. 2011
    ..These observations provide consistent evidence that genetic variants at the NCOA7 locus may confer a reduced risk of breast cancer...
  22. doi request reprint Vitamin D insufficiency among African-Americans in the southeastern United States: implications for cancer disparities (United States)
    Kathleen M Egan
    Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN, USA
    Cancer Causes Control 19:527-35. 2008
    ..To determine the prevalence and predictors of vitamin D insufficiency among black and white adult residents of the southern US...
  23. ncbi request reprint Antioxidant intake and primary open-angle glaucoma: a prospective study
    Jae H Kang
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Epidemiol 158:337-46. 2003
    ..97 (95% CI: 0.62, 1.52) for vitamin E, and 1.11 (95% CI: 0.82, 1.51) for vitamin A. In conclusion, the authors did not observe any strong associations between antioxidant consumption and the risk of primary open-angle glaucoma...
  24. ncbi request reprint Genetic polymorphisms in base-excision repair pathway genes and risk of breast cancer
    Yawei Zhang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 15:353-8. 2006
    ..6; 95% CI, 1.1-2.4; P = 0.02). In conclusion, our results do not support that the polymorphisms evaluated in six BER pathway genes play a major role in breast carcinogenesis, particularly in Caucasian populations...
  25. ncbi request reprint Cigarette smoking and risk of breast carcinoma in situ
    Amy Trentham-Dietz
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Madison, Wisconsin 53726, USA
    Epidemiology 18:629-38. 2007
    ..Although the associations with cigarette smoking have been explored extensively for invasive breast cancer, the relation to in situ cancer has not previously been examined in depth...
  26. ncbi request reprint Statin use and risk of breast cancer
    Gaia Pocobelli
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Cancer 112:27-33. 2008
    ..We analyzed data from a population-based case-control study to evaluate the association between the use of statins and breast cancer risk...
  27. pmc Prediagnostic use of hormone therapy and mortality after breast cancer
    Polly A Newcomb
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 17:864-71. 2008
    ..Due to the high prevalence of past and current hormone use, it is important to investigate whether these preparations are related to breast cancer mortality...
  28. ncbi request reprint Early life risk factors in cancer: the relation of birth weight to adult obesity
    Nicole M Leong
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 103:789-91. 2003
    ..76). These data suggest that both low and high birth weights are associated with higher adult BMI and support the hypothesis that fetal experience may influence adult obesity with potential consequences for risk of several major cancers...
  29. pmc Proportion of invasive breast cancer attributable to risk factors modifiable after menopause
    Brian L Sprague
    Department of Population Health Sciences, University of Wisconsin Madison, Madison, WI 53726, USA
    Am J Epidemiol 168:404-11. 2008
    ..3%. These findings suggest that a substantial fraction of postmenopausal breast cancer may be avoided by purposeful changes in lifestyle later in life...
  30. ncbi request reprint Genetic variation in TP53 and risk of breast cancer in a population-based case control study
    Brian L Sprague
    Department of Population Health Sciences, University of Wisconsin Madison, Madison, WI 53726, USA
    Carcinogenesis 28:1680-6. 2007
    ..03). These results indicate that common variation in the TP53 gene could modify the risk of invasive breast cancer...
  31. ncbi request reprint Occupational exposure to electromagnetic field and breast cancer risk in a large, population-based, case-control study in the United States
    Jane A McElroy
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Madison, WI 53726, USA
    J Occup Environ Med 49:266-74. 2007
    ..Our objective was to evaluate women who were occupationally exposed to electromagnetic fields (EMF) and breast cancer risk...
  32. ncbi request reprint Postmenopausal estrogen and progestin use in relation to breast cancer risk
    Polly A Newcomb
    University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin 53706, USA
    Cancer Epidemiol Biomarkers Prev 11:593-600. 2002
    ..09; 95% CI, 1.07-4.07 for ever use versus nonuse). Estrogen-progestin use, both sequential and continuous, appears to be more strongly associated with risk of breast cancer than use of estrogen alone...
  33. ncbi request reprint Dietary fat consumption and primary open-angle glaucoma
    Jae H Kang
    Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 79:755-64. 2004
    ..Prostaglandin F(2alpha) analogues are effective intraocular-pressure-lowering drugs. Dietary fatty acids affect endogenous prostaglandin F(2alpha) concentrations and may thus influence intraocular pressure...
  34. ncbi request reprint Sunlight and reduced risk of cancer: is the real story vitamin D?
    Kathleen M Egan
    J Natl Cancer Inst 97:161-3. 2005
  35. ncbi request reprint Recreational physical activity and ovarian cancer in a population-based case-control study
    Elizabeth R Bertone
    Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003 9304, USA
    Int J Cancer 99:431-6. 2002
    ..70; 95% CI = 0.36-1.35; p for trend = 0.41). Overall, our results provide only limited support for an inverse association between recreational physical activity and risk of ovarian cancer...
  36. ncbi request reprint Polymorphisms in DNA double-strand break repair genes and risk of breast cancer: two population-based studies in USA and Poland, and meta-analyses
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Room 7076, Rockville, MD 20952 7234, USA
    Hum Genet 119:376-88. 2006
    ..Evaluation of potential underlying gene-gene interactions or associations in population subgroups will require even larger sample sizes...
  37. ncbi request reprint Vitamin D receptor polymorphism and breast cancer risk
    Polly A Newcomb
    Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer Epidemiol Biomarkers Prev 11:1503-4. 2002
  38. ncbi request reprint Duration of sleep and breast cancer risk in a large population-based case-control study
    Jane A McElroy
    University of Wisconsin Comprehensive Cancer Center, Madison, 53726, USA
    J Sleep Res 15:241-9. 2006
    ..In contrast, short duration of sleep (<7 h/night) is not substantially associated with increased risk. Further research in this area is warranted...
  39. ncbi request reprint Familial relative risk estimates for use in epidemiologic analyses
    Yutaka Yasui
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Am J Epidemiol 164:697-705. 2006
    ....
  40. ncbi request reprint From menarche to menopause: trends among US Women born from 1912 to 1969
    Hazel B Nichols
    University of Wisconsin Comprehensive Cancer Center, Madison, WI 53726, USA
    Am J Epidemiol 164:1003-11. 2006
    ..1 years among women born between 1915 and 1919 to 37.7 years among the 1935-1939 cohort (p = 0.0001). These findings have implications for women's lifetime exposure to circulating endogenous hormones...
  41. ncbi request reprint Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Hum Genet 121:483-90. 2007
    ..Additional studies are required to replicate these findings and to determine whether rs361525 is a causative SNP or is a marker of a causative SNP...
  42. ncbi request reprint Lifetime recreational and occupational physical activity and risk of in situ and invasive breast cancer
    Brian L Sprague
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Department of Population Health Sciences, University of Wisconsin Madison, Madison, Wisconsin 53726, USA
    Cancer Epidemiol Biomarkers Prev 16:236-43. 2007
    ..Lifetime strenuous occupational activity was not associated with invasive breast cancer risk. These results provide further evidence that, for most women, physical activity may reduce the risk of invasive breast cancer...
  43. ncbi request reprint Active and passive smoking in breast cancer: prospective results from the Nurses' Health Study
    Kathleen M Egan
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 13:138-45. 2002
    ..The role of active and passive smoking in breast cancer remains controversial...
  44. ncbi request reprint Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin
    Teresa T Fung
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 103:110-5. 2003
    ..No evidence was found that vitamins A, C and E; folate; or carotenoids play an important protective role against incident SCC...
  45. ncbi request reprint Conservation treatment of the eye: Conformal proton reirradiation for recurrent uveal melanoma
    Laura Marucci
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 64:1018-22. 2006
    ..To evaluate the outcomes of a second course of proton beam radiation therapy (PBRT) in patients with recurrent uveal melanoma...
  46. ncbi request reprint Dairy food and ovarian cancer risk
    Polly A Newcomb
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Lancet 367:797-9. 2006
  47. ncbi request reprint Oral contraceptive use and risk of breast carcinoma in situ
    Hazel B Nichols
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, University of Wisconsin, Madison, WI 53726, USA
    Cancer Epidemiol Biomarkers Prev 16:2262-8. 2007
    ..16; 95% CI, 1.01-1.32 for ever versus never use). Consistent with invasive breast cancer, these results suggest that oral contraceptive use is at most a minor contributor to BCIS risk...
  48. doi request reprint Physical activity and survival after diagnosis of invasive breast cancer
    Crystal N Holick
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Cancer Epidemiol Biomarkers Prev 17:379-86. 2008
    ..This study provides support for reduced overall mortality and mortality from breast cancer among women who engage in physical activity after breast cancer diagnosis...