Logan Dumitrescu

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 515B Light Hall, Nashville, TN, 37232, USA
    Hum Genet 132:1427-31. 2013
  2. pmc Serum vitamins A and E as modifiers of lipid trait genetics in the National Health and Nutrition Examination Surveys as part of the Population Architecture using Genomics and Epidemiology (PAGE) study
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 515B Light Hall, Nashville, TN 37232, USA
    Hum Genet 131:1699-708. 2012
  3. pmc Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study
    Kira C Taylor
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    BMC Genet 14:33. 2013
  4. pmc Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS Genet 7:e1002138. 2011
  5. pmc Post-Genome-Wide Association Study Challenges for Lipid Traits: Describing Age as a Modifier of Gene-Lipid Associations in the Population Architecture Using Genomics and Epidemiology (PAGE) Study
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, Nashville, TN
    Ann Hum Genet 77:416-25. 2013
  6. pmc Evidence for age as a modifier of genetic associations for lipid levels
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37232, USA
    Ann Hum Genet 75:589-97. 2011
  7. pmc Variation in LPA is associated with Lp(a) levels in three populations from the Third National Health and Nutrition Examination Survey
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 6:e16604. 2011
  8. pmc Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records
    Logan Dumitrescu
    Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA
    Genet Med 12:648-50. 2010
  9. pmc Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank
    Jacob B Hall
    Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 9:e99161. 2014
  10. pmc Atopy history and the genomics of wheezing after influenza vaccination in children 6-59 months of age
    E Kathryn Miller
    Department of Pediatrics, Vanderbilt University Medical Center, CCC 5323 Medical Center North, Nashville, TN 37232, USA
    Vaccine 29:3431-7. 2011

Collaborators

Detail Information

Publications11

  1. pmc No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 515B Light Hall, Nashville, TN, 37232, USA
    Hum Genet 132:1427-31. 2013
    ..Despite their biological plausibility, we were unable to detect significant SNP × smoking interactions...
  2. pmc Serum vitamins A and E as modifiers of lipid trait genetics in the National Health and Nutrition Examination Surveys as part of the Population Architecture using Genomics and Epidemiology (PAGE) study
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 515B Light Hall, Nashville, TN 37232, USA
    Hum Genet 131:1699-708. 2012
    ....
  3. pmc Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study
    Kira C Taylor
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    BMC Genet 14:33. 2013
    ..Here, we investigated whether GWAS-identified SNPs for lipid traits exhibited heterogeneity by sex in the Population Architecture using Genomics and Epidemiology (PAGE) study...
  4. pmc Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS Genet 7:e1002138. 2011
    ..For the associations that did not generalize, differences in effect sizes, allele frequencies, and linkage disequilibrium offer clues to the next generation of association studies for these traits...
  5. pmc Post-Genome-Wide Association Study Challenges for Lipid Traits: Describing Age as a Modifier of Gene-Lipid Associations in the Population Architecture Using Genomics and Epidemiology (PAGE) Study
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, Nashville, TN
    Ann Hum Genet 77:416-25. 2013
    ..99). However, none of the suggestive modifying effects survived adjustment for multiple testing, highlighting the challenges of identifying modifiers of modest SNP-trait associations despite large sample sizes. ..
  6. pmc Evidence for age as a modifier of genetic associations for lipid levels
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37232, USA
    Ann Hum Genet 75:589-97. 2011
    ..This finding illustrates the utility of using children to discover novel variants associated with complex phenotypes and the importance of considering age-dependent genetic effects in association studies of lipid levels...
  7. pmc Variation in LPA is associated with Lp(a) levels in three populations from the Third National Health and Nutrition Examination Survey
    Logan Dumitrescu
    Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 6:e16604. 2011
    ....
  8. pmc Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records
    Logan Dumitrescu
    Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA
    Genet Med 12:648-50. 2010
    ....
  9. pmc Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank
    Jacob B Hall
    Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 9:e99161. 2014
    ..These results suggest caution when selecting study samples of non-African and non-European backgrounds when administratively-assigned race from biobanks is used. ..
  10. pmc Atopy history and the genomics of wheezing after influenza vaccination in children 6-59 months of age
    E Kathryn Miller
    Department of Pediatrics, Vanderbilt University Medical Center, CCC 5323 Medical Center North, Nashville, TN 37232, USA
    Vaccine 29:3431-7. 2011
    ..We sought to determine whether epidemiologic or genetic factors were associated with these outcomes...
  11. pmc Peptide tyrosine tyrosine levels are increased in patients with urea cycle disorders
    Sabrina Mitchell
    Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Mol Genet Metab 106:39-42. 2012
    ..These observations may lead to a better understanding of the development of anorexia in UCD patients...