Lesly A Dossett

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. doi request reprint Cost-effectiveness of routine radiographs after emergent open cavity operations
    Lesly A Dossett
    Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA
    Surgery 144:317-21. 2008
  2. ncbi request reprint Small bowel adenocarcinoma complicating Crohn's disease: case series and review of the literature
    Lesly A Dossett
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Am Surg 73:1181-7. 2007
  3. pmc Obesity and pulmonary complications in critically injured adults
    Lesly A Dossett
    Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA
    Chest 134:974-80. 2008
  4. pmc High levels of endogenous estrogens are associated with death in the critically injured adult
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center Nashville, Tennessee, USA
    J Trauma 64:580-5. 2008
  5. ncbi request reprint Blood glucose variability is associated with mortality in the surgical intensive care unit
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Am Surg 74:679-85; discussion 685. 2008
  6. pmc Revisiting the validity of APACHE II in the trauma ICU: improved risk stratification in critically injured adults
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, 404 Medical Arts Building, Nashville, TN 37212, USA
    Injury 40:993-8. 2009
  7. ncbi request reprint Sex- and diagnosis-dependent differences in mortality and admission cytokine levels among patients admitted for intensive care
    Christopher A Guidry
    1Department of Surgery, University of Virginia Health System, Charlottesville, VA 2Department of Surgery, University of Minnesota, Minneapolis, MN 3Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 4Department of Surgery, University of Washington, Seattle, WA 5Department of Surgery, University of Alabama Birmingham, Birmingham, AL 6Department of Public Health Sciences, University of Virginia Health System, Charlottesville, VA
    Crit Care Med 42:1110-20. 2014
  8. doi request reprint Severe hypoglycemia while on intensive insulin therapy is not an independent predictor of death after trauma
    Nathan T Mowery
    Department of Surgery, Wake Forest Baptist Medical Center, Winston Salem, North Carolina, USA
    J Trauma 68:342-7. 2010
  9. doi request reprint Intensive insulin therapy in practice: can we do it?
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37212, USA
    JPEN J Parenter Enteral Nutr 33:14-20. 2009
  10. doi request reprint Stress insulin resistance is a marker for mortality in traumatic brain injury
    Nathan T Mowery
    Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    J Trauma 66:145-51; discussion 151-3. 2009

Detail Information

Publications32

  1. doi request reprint Cost-effectiveness of routine radiographs after emergent open cavity operations
    Lesly A Dossett
    Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA
    Surgery 144:317-21. 2008
    ..We hypothesized that the institutional costs resulting from a RSS would make routine intraoperative radiography (IOR) more cost-effective than surgical counts in preventing RSS after emergent open cavity cases...
  2. ncbi request reprint Small bowel adenocarcinoma complicating Crohn's disease: case series and review of the literature
    Lesly A Dossett
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Am Surg 73:1181-7. 2007
    ..Patients with SBA and CD are, as a group, younger and more likely to be male. SBA is rarely diagnosed preoperatively in these patients, and has a poor prognosis due to its advanced stage at diagnosis...
  3. pmc Obesity and pulmonary complications in critically injured adults
    Lesly A Dossett
    Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA
    Chest 134:974-80. 2008
    ..Whether or not obesity contributes to pulmonary complications after critical injury is poorly understood...
  4. pmc High levels of endogenous estrogens are associated with death in the critically injured adult
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center Nashville, Tennessee, USA
    J Trauma 64:580-5. 2008
    ..Our objective was to determine the relationship between endogenous estrogens and outcomes in critically injured patients...
  5. ncbi request reprint Blood glucose variability is associated with mortality in the surgical intensive care unit
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Am Surg 74:679-85; discussion 685. 2008
    ..Further studies should focus on the demographic, clinical, and genetic factors responsible for this observation and identify strategies to minimize BG variability...
  6. pmc Revisiting the validity of APACHE II in the trauma ICU: improved risk stratification in critically injured adults
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, 404 Medical Arts Building, Nashville, TN 37212, USA
    Injury 40:993-8. 2009
    ....
  7. ncbi request reprint Sex- and diagnosis-dependent differences in mortality and admission cytokine levels among patients admitted for intensive care
    Christopher A Guidry
    1Department of Surgery, University of Virginia Health System, Charlottesville, VA 2Department of Surgery, University of Minnesota, Minneapolis, MN 3Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 4Department of Surgery, University of Washington, Seattle, WA 5Department of Surgery, University of Alabama Birmingham, Birmingham, AL 6Department of Public Health Sciences, University of Virginia Health System, Charlottesville, VA
    Crit Care Med 42:1110-20. 2014
    ..To investigate the role of sex on cytokine expression and mortality in critically ill patients...
  8. doi request reprint Severe hypoglycemia while on intensive insulin therapy is not an independent predictor of death after trauma
    Nathan T Mowery
    Department of Surgery, Wake Forest Baptist Medical Center, Winston Salem, North Carolina, USA
    J Trauma 68:342-7. 2010
    ..We hypothesized that severe hypoglycemia (SH; <or=40 mg/dL) was not an independent predictor of mortality in the trauma population...
  9. doi request reprint Intensive insulin therapy in practice: can we do it?
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37212, USA
    JPEN J Parenter Enteral Nutr 33:14-20. 2009
    ..The authors' objective was to quantify adherence to an IIT protocol in a practice setting, and to describe how adherence impacts overall blood glucose (BG) control...
  10. doi request reprint Stress insulin resistance is a marker for mortality in traumatic brain injury
    Nathan T Mowery
    Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    J Trauma 66:145-51; discussion 151-3. 2009
    ..Both hyper- and hypoglycemia have been associated with poor outcome in traumatic brain injury (TBI). Neither the risks nor benefit of tight glucose control (goal range, 80-110 mg/dL) have been documented in the TBI population...
  11. doi request reprint Insulin resistance heralds positive cultures after severe injury
    Nathan T Mowery
    Department of Surgery, Vanderbilt University, Nashville, Tennessee, USA
    Surg Infect (Larchmt) 10:503-9. 2009
    ..We hypothesized that measures of IR during tight glycemic control protocols are associated with infection and may be more predictive than the serum glucose concentration...
  12. ncbi request reprint Glucose metabolism, not obesity, predicts mortality in critically ill surgical patients
    Nathan T Mowery
    Department of Surgery, Wake Forest Baptist Medical Center, Winston Salem, North Carolina 27157, USA
    Am Surg 76:1377-83. 2010
    ..Obesity is not an independent risk factor for mortality in the surgical critical care population. Insulin resistance and subsequent hyperglycemia are increased in obesity and are independent predictors of mortality...
  13. pmc Trends in estradiol during critical illness are associated with mortality independent of admission estradiol
    Rondi M Kauffmann
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37212, USA
    J Am Coll Surg 212:703-12; discussion 712-3. 2011
    ..We hypothesized that changes from baseline serum E(2) during the course of critical illness are more strongly associated with mortality than a single E(2) level at admission...
  14. pmc Diagnosis-dependent relationships between cytokine levels and survival in patients admitted for surgical critical care
    Tjasa Hranjec
    Division of Trauma and Surgical Critical Care, Department of Surgery, University of Virginia, Charlottesville, VA 22908, USA
    J Am Coll Surg 210:833-44, 845-6. 2010
    ..We hypothesized that admission cytokine profiles associated with death would differ based on admitting diagnosis...
  15. pmc Gender and acute respiratory distress syndrome in critically injured adults: a prospective study
    Daithi S Heffernan
    Division of Trauma and Surgical Critical Care, Department of Surgery, Warren Alpert Medical School, Brown University, Rhode Island Hospital, Providence, Rhode Island 02903, USA
    J Trauma 71:878-83; discussion 883-5. 2011
    ..Human data are scant regarding the role of gender and sex hormones in developing ARDS. Our objective was to describe gender and hormonal differences in patients who develop ARDS in a large cohort of critically injured adults...
  16. doi request reprint Room for (performance) improvement: provider-related factors associated with poor outcomes in massive transfusion
    Bryan A Cotton
    Department of Surgery, Center for Translational Injury Research, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 67:1004-12. 2009
    ..The purpose of this study was to identify the incidence and impact of MT protocol noncompliance and to intervene in provider-related events associated with poor compliance and outcomes...
  17. pmc Serum estradiol concentration as a predictor of death in critically ill and injured adults
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA
    Surg Infect (Larchmt) 9:41-8. 2008
    ..Our objective was to determine the predictive ability and test characteristics of the serum estradiol concentration at 48 h in critically ill patients...
  18. pmc Obesity and site-specific nosocomial infection risk in the intensive care unit
    Lesly A Dossett
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA
    Surg Infect (Larchmt) 10:137-42. 2009
    ..Our objective was to describe the relation between body mass index (BMI) and site-specific ICU-acquired infection risk in adults...
  19. doi request reprint Prevalence and implications of preinjury warfarin use: an analysis of the National Trauma Databank
    Lesly A Dossett
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Arch Surg 146:565-70. 2011
    ..To describe the prevalence of preinjury warfarin use in a large national sample of trauma patients and to define the relationship between preinjury warfarin use and mortality...
  20. ncbi request reprint Insulin resistance despite tight glucose control is associated with mortality in critically ill surgical patients
    Nathan T Mowery
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Intensive Care Med 24:242-51. 2009
    ..The hyperglycemic state following trauma and surgery is related partially to insulin resistance (IR). The objective is to determine if critically ill surgical patients vary in their extent of IR and is IR associated with mortality...
  21. doi request reprint Postoperative neuromuscular blocker use is associated with higher primary fascial closure rates after damage control laparotomy
    Chadi T Abouassaly
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Trauma 69:557-61. 2010
    ..The purpose of this study was to determine whether exposure to NMBA is associated a higher likelihood of primary fascial closure...
  22. pmc Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis
    Richard D Fremont
    Division of Allergy, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2650, USA
    J Trauma 68:1121-7. 2010
    ..The aims of this study were to develop a panel of plasma biomarkers to facilitate diagnosis of trauma-induced ALI and to enhance our understanding of the pathogenesis of human ALI...
  23. doi request reprint Impact of high-dose antioxidants on outcomes in acutely injured patients
    Bryan R Collier
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37212, USA
    JPEN J Parenter Enteral Nutr 32:384-8. 2008
    ..The purpose of this study was to evaluate the impact of high-dose antioxidant administration on the mortality rate of acutely injured patients...
  24. doi request reprint Infection reduction strategies including antibiotic stewardship protocols in surgical and trauma intensive care units are associated with reduced resistant gram-negative healthcare-associated infections
    Marcus J Dortch
    Department of Pharmaceutical Services, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN 37232, USA
    Surg Infect (Larchmt) 12:15-25. 2011
    ..We describe the implementation of infection reduction protocols, including antibiotic stewardship, and assess their impact on multi-drug-resistant (MDR) healthcare-acquired gram-negative infections...
  25. pmc Estradiol is associated with mortality in critically ill trauma and surgical patients
    Addison K May
    Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA
    Crit Care Med 36:62-8. 2008
    ..Our objective was to determine whether sex hormone levels were associated with outcomes in critically ill surgical patients...
  26. pmc Severe traumatic head injury affects systemic cytokine expression
    Damien J LaPar
    Division of Trauma and Surgical Critical Care, Department of Surgery, University of Virginia, Charlottesville, VA 22903, USA
    J Am Coll Surg 214:478-86; discussion 486-8. 2012
    ..This study aimed to characterize systemic cytokine profiles among traumatically injured patients to assess the effect of traumatic head injury on the systemic inflammatory response...
  27. doi request reprint Use of scene vital signs improves TRISS predicted survival in intubated trauma patients
    Igor V Voskresensky
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37212, USA
    J Surg Res 154:105-11. 2009
    ..The purpose of this study was to assess the impact of scene vital signs on predicting survival in intubated trauma patients...
  28. ncbi request reprint Glucose control and the inflammatory response
    Bryan Collier
    Division of Trauma and Surgical Critical Care, 1211 21st Avenue, Department of Surgery, Vanderbilt University Medical Center, 404 Medical Arts Building, Nashville, TN 37212, USA
    Nutr Clin Pract 23:3-15. 2008
    ..Understanding the pathophysiology driving stress hyperglycemia--the stress response and modulation of the inflammatory process-seems to be the key to improving the care of the most critically ill and injured patients...
  29. doi request reprint Early prediction of massive transfusion in trauma: simple as ABC (assessment of blood consumption)?
    Timothy C Nunez
    Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Trauma 66:346-52. 2009
    ..The purpose of this study was to validate previously described MT scoring systems and compare these to a simplified nonlaboratory dependent scoring system (Assessment of Blood Consumption [ABC] score)...
  30. doi request reprint Implementation of a real-time compliance dashboard to help reduce SICU ventilator-associated pneumonia with the ventilator bundle
    Victor Zaydfudim
    Department of Surgery, Vanderbilt University Medical Center, D 4314 Medical Center North, Nashville, TN 37232 2730, USA
    Arch Surg 144:656-62. 2009
    ..Recent studies suggest that the success of preventive measures is dependent on compliance with ventilator bundle parameters...
  31. doi request reprint Risk factors for treatment failure in patients receiving vancomycin for hospital-acquired methicillin-resistant Staphylococcus aureus pneumonia
    Jonathan L Aston
    Department of Pharmaceutical Services, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232 7610, USA
    Surg Infect (Larchmt) 11:21-8. 2010
    ..We sought to identify contributors to vancomycin failure in patients with MRSA HAP...
  32. doi request reprint Unwarranted national variation in the use of prophylactic inferior vena cava filters after trauma: an analysis of the National Trauma Databank
    Lesly A Dossett
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Trauma 70:1066-70; discussion 1070-1. 2011
    ..S. trauma centers would practice according to Eastern Association for the Surgery of Trauma guidelines and that any variation in practice patterns would be due to variations in the number of high-risk patients treated...