Qi Dai

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Fruit and vegetable juices and Alzheimer's disease: the Kame Project
    Qi Dai
    Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt Center for Health Services Research, Vanderbilt Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, Tenn, USA
    Am J Med 119:751-9. 2006
  2. pmc Association of high blood pressure with renal insufficiency: role of albuminuria, from NHANES, 1999-2006
    Ping Yan
    Department of Cardiology, Huashan Hospital, Fudan University, Shanghai, People s Republic of China
    PLoS ONE 7:e37837. 2012
  3. pmc Renal function, bisphenol A, and alkylphenols: results from the National Health and Nutrition Examination Survey (NHANES 2003-2006)
    Li You
    Division of Nephrology, Huashan Hospital, Fudan University, Shanghai, China
    Environ Health Perspect 119:527-33. 2011
  4. pmc Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III
    Xinqing Deng
    Department of Medicine, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
    BMC Med 11:187. 2013
  5. pmc The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk
    Qi Dai
    Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 86:743-51. 2007
  6. pmc Blood magnesium, and the interaction with calcium, on the risk of high-grade prostate cancer
    Qi Dai
    Vanderbilt University Medical Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
    PLoS ONE 6:e18237. 2011
  7. pmc Is green tea drinking associated with a later onset of breast cancer?
    Qi Dai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN 37203 1738, USA
    Ann Epidemiol 20:74-81. 2010
  8. pmc Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study
    Qi Dai
    Department of Medicine and Pharmacology, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Nashville, TN 37203 1738, USA
    J Clin Oncol 27:2482-8. 2009
  9. pmc Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself
    Tsogzolmaa Dorjgochoo
    Divisions of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Clin Nutr 96:405-14. 2012
  10. ncbi request reprint MTR and MTRR polymorphisms, dietary intake, and breast cancer risk
    Martha J Shrubsole
    Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN 37232 2587, USA
    Cancer Epidemiol Biomarkers Prev 15:586-8. 2006

Collaborators

Detail Information

Publications79

  1. pmc Fruit and vegetable juices and Alzheimer's disease: the Kame Project
    Qi Dai
    Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt Center for Health Services Research, Vanderbilt Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, Tenn, USA
    Am J Med 119:751-9. 2006
    ..Many polyphenols, the most abundant dietary antioxidants, possess stronger neuroprotection against hydrogen peroxide than antioxidant vitamins...
  2. pmc Association of high blood pressure with renal insufficiency: role of albuminuria, from NHANES, 1999-2006
    Ping Yan
    Department of Cardiology, Huashan Hospital, Fudan University, Shanghai, People s Republic of China
    PLoS ONE 7:e37837. 2012
    ..However, the underlying mechanism has been unclear...
  3. pmc Renal function, bisphenol A, and alkylphenols: results from the National Health and Nutrition Examination Survey (NHANES 2003-2006)
    Li You
    Division of Nephrology, Huashan Hospital, Fudan University, Shanghai, China
    Environ Health Perspect 119:527-33. 2011
    ..Urinary excretion of bisphenol A (BPA) and alkylphenols (APs) was used as a biomarker in most previous studies, but no study has investigated whether urinary excretion of these environmental phenols differed by renal function...
  4. pmc Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III
    Xinqing Deng
    Department of Medicine, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
    BMC Med 11:187. 2013
    ....
  5. pmc The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk
    Qi Dai
    Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 86:743-51. 2007
    ..Transient receptor potential melastatin 7 (TRPM7) is a newly found gene essential to magnesium absorption and homeostasis...
  6. pmc Blood magnesium, and the interaction with calcium, on the risk of high-grade prostate cancer
    Qi Dai
    Vanderbilt University Medical Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
    PLoS ONE 6:e18237. 2011
    ..We hypothesized that inadequate Mg levels, perhaps relative to Ca levels (e.g. a high Ca/Mg ratio) are associated with greater prostate cancer risk...
  7. pmc Is green tea drinking associated with a later onset of breast cancer?
    Qi Dai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN 37203 1738, USA
    Ann Epidemiol 20:74-81. 2010
    ..Because of the substantial difference in levels of estrogens between premenopausal and postmenopausal women, the relationship between tea consumption and breast cancer risk may depend on menopausal status...
  8. pmc Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study
    Qi Dai
    Department of Medicine and Pharmacology, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Nashville, TN 37203 1738, USA
    J Clin Oncol 27:2482-8. 2009
    ..No prospective study has investigated whether levels of 15-F(2t)-isoprostane (15-F(2t)-IsoP) and its metabolite 2,3-dinor-5,6-dihydro-15-F(2t)-IsoP (15-F(2t)-IsoPM) are related to breast cancer risk...
  9. pmc Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself
    Tsogzolmaa Dorjgochoo
    Divisions of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Clin Nutr 96:405-14. 2012
    ..There is limited literature on the contributors to isoprostane metabolite 2,3-dinor-5,6-dihydro-15-F(2t)-isoprostane (15-F(2t)-IsoP-M) compared with F(2)-isoprostanes (F(2)-IsoPs) as an oxidative stress biomarker...
  10. ncbi request reprint MTR and MTRR polymorphisms, dietary intake, and breast cancer risk
    Martha J Shrubsole
    Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN 37232 2587, USA
    Cancer Epidemiol Biomarkers Prev 15:586-8. 2006
  11. pmc Energy balance, insulin resistance biomarkers, and breast cancer risk
    Alecia Malin Fair
    Meharry Medical College, School of Medicine, Department of Surgery, 1005 Dr D B Todd Jr Boulevard, Nashville, TN 37208 3599, USA
    Cancer Detect Prev 31:214-9. 2007
    ....
  12. ncbi request reprint Oral contraceptive use and breast cancer risk: modification by NAD(P)H:quinone oxoreductase (NQO1) genetic polymorphisms
    Jay H Fowke
    Center for Health Services Research, Vanderbilt University Medical Center, 6110 Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:1308-15. 2004
    ..43-6.25; C/T or T/T OR 0.49, 95% CI 0.29-0.81; P for interaction < 0.01). Our results require confirmation but suggest that the OC and breast cancer association depends on the ability to invoke protection from catechol estrogens...
  13. pmc Interaction of soy food and tea consumption with CYP19A1 genetic polymorphisms in the development of endometrial cancer
    Wang Hong Xu
    Department of Epidemiology, Shanghai Cancer Institute and Cancer Institute of Shanghai Jiao Tong University, Shanghai, People s Republic of China
    Am J Epidemiol 166:1420-30. 2007
    ..05) but not by soy isoflavone intake. The authors' findings suggest that tea polyphenols may modify the effect of CYP19A1 genetic polymorphisms on the development of endometrial cancer...
  14. ncbi request reprint Two-stage case-control study of common ATM gene variants in relation to breast cancer risk
    Chuanzhong Ye
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232 2587, USA
    Breast Cancer Res Treat 106:121-6. 2007
    ....
  15. ncbi request reprint MTHFR polymorphisms, dietary folate intake, and breast cancer risk: results from the Shanghai Breast Cancer Study
    Martha J Shrubsole
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:190-6. 2004
    ..Results of this study suggest that the MTHFR C677T polymorphisms may modify the association between dietary folate intake and breast cancer risk...
  16. ncbi request reprint Population-based case-control study of CYP11A gene polymorphism and breast cancer risk
    Wei Zheng
    Drpartment of Medicine and Vanderbilt Ingram Cancer Centr, Vanderbilt University, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 13:709-14. 2004
    ..The results from this study indicate that the TAAAA repeat polymorphism near the promoter region of the CYP11A gene may be an important susceptibility factor for breast cancer risk...
  17. pmc Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: results from the Shanghai Breast Cancer Study
    Qiuyin Cai
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
    Breast Cancer Res 6:R647-55. 2004
    ....
  18. pmc Obesity, age, and oxidative stress in middle-aged and older women
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Ave, Nashville, TN 37203 1738, USA
    Antioxid Redox Signal 14:2453-60. 2011
    ..15-F(2t)-IsoP-M appears to be a valuable biomarker of oxidative stress in age- and obesity-related diseases...
  19. ncbi request reprint Population-based case-control study of AhR (aryl hydrocarbon receptor) and CYP1A2 polymorphisms and breast cancer risk
    Ji Rong Long
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, Nashville, TN 37232, USA
    Pharmacogenet Genomics 16:237-43. 2006
    ....
  20. ncbi request reprint Urinary phytoestrogen excretion and breast cancer risk: evaluating potential effect modifiers endogenous estrogens and anthropometrics
    Qi Dai
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 12:497-502. 2003
    ..Findings from this study suggest that the potential protective association of phytoestrogens may be modified by BMI, WHR, and blood levels of SHBG, and steroid hormones...
  21. pmc Urinary polyphenols and breast cancer risk: results from the Shanghai Women's Health Study
    Jianfeng Luo
    Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Breast Cancer Res Treat 120:693-702. 2010
    ..In conclusion, high epicatechin may be related to a reduced risk of breast cancer. Further studies are warranted to confirm our findings...
  22. pmc Interaction of soy and 17beta-HSD1 gene polymorphisms in the risk of endometrial cancer
    Qi Dai
    Department of Medicine and Vanderbilt Ingram Cancer Center, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Pharmacogenet Genomics 17:161-7. 2007
    ..In-vitro studies have found that soy isoflavones can inhibit the activity of 17beta-hydroxysteroid dehydrogenase type I, a key enzyme in catalyzing estrone (E1), to the biologically more active estradiol (E2)...
  23. pmc Calcium intake and lung cancer risk among female nonsmokers: a report from the Shanghai Women's Health Study
    Yumie Takata
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
    Cancer Epidemiol Biomarkers Prev 22:50-7. 2013
    ..Calcium has been implicated in carcinogenesis and linked to the risk of several cancers in epidemiologic studies; however, few studies have investigated the association of calcium intake with lung cancer risk, particularly among nonsmokers...
  24. ncbi request reprint Genetic polymorphisms in GSTM1, GSTP1, and GSTT1 and the risk for breast cancer: results from the Shanghai Breast Cancer Study and meta-analysis
    Kathleen M Egan
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 27232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:197-204. 2004
    ....
  25. pmc Energy balance and breast cancer risk
    Alecia Malin
    Department of Surgery, Meharry Medical College, 1005 Dr D B Todd Boulevard, Nashville, Tennessee 37208, USA
    Cancer Epidemiol Biomarkers Prev 14:1496-501. 2005
    ..74; 95% confidence interval, 2.05-12.20). Our study suggests that promotion of behavior patterns that optimize energy balance (weight control and increasing physical activity) may be a viable option for breast cancer prevention...
  26. pmc Urinary polyphenols, glutathione S-transferases copy number variation, and breast cancer risk: results from the Shanghai women's health study
    Jianfeng Luo
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203 1738, USA
    Mol Carcinog 51:379-88. 2012
    ..The differential associations between polyphenols and breast cancer risk by GST polymorphisms, if confirmed, may provide a new avenue for the personalized prevention of breast cancer...
  27. pmc Dietary intake of PUFAs and colorectal polyp risk
    Harvey J Murff
    Division of General Internal Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
    Am J Clin Nutr 95:703-12. 2012
    ..Marine-derived n-3 (omega-3) PUFAs may reduce risk of developing colorectal cancer; however, few studies have investigated the association of n-3 PUFA intakes on colorectal polyp risk...
  28. pmc Dietary calcium and magnesium intakes and the risk of type 2 diabetes: the Shanghai Women's Health Study
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:1059-67. 2009
    ..Diet plays a key role in the development of type 2 diabetes (T2D), but little is known about the contributions of specific nutrients in populations in which dietary patterns differ from Western populations...
  29. ncbi request reprint Dietary animal-derived iron and fat intake and breast cancer risk in the Shanghai Breast Cancer Study
    Asha R Kallianpur
    Division of General Internal Medicine and Public Health, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
    Breast Cancer Res Treat 107:123-32. 2008
    ..Iron, an essential micronutrient with pro-oxidant properties, has received little attention, and specific fats may augment its toxicity. We investigated the effects of iron and fats from various food sources on the risk of breast cancer...
  30. ncbi request reprint Urinary isothiocyanate excretion, brassica consumption, and gene polymorphisms among women living in Shanghai, China
    Jay H Fowke
    Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 12:1536-9. 2003
    ..In conclusion, a single urinary ITC measure, in conjunction with markers of Phase II enzyme activity, provides a complementary measure of habitual Brassica intake among Shanghai women...
  31. pmc Haplotype analysis of CYP11A1 identifies promoter variants associated with breast cancer risk
    Brian L Yaspan
    Department of Cancer Biology, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, TN 37232 0275, USA
    Cancer Res 67:5673-82. 2007
    ..94 (95% CI, 1.22-7.12), test for trend, P = 5.0e-5. Among genes controlling endogenous estrogen metabolism, CYP11A1 harbors common variants that may influence expression to significantly modify risk of breast cancer...
  32. pmc Genome-wide association study identifies possible genetic risk factors for colorectal adenomas
    Todd L Edwards
    Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, TN 37203, USA
    Cancer Epidemiol Biomarkers Prev 22:1219-26. 2013
    ..Removal of polyps reduces mortality from colorectal cancer. Colorectal adenomas are known to aggregate in families; however, the genetic determinants for risk of polyps are largely unknown...
  33. ncbi request reprint Genetic polymorphisms in the estrogen receptor alpha gene and risk of breast cancer: results from the Shanghai Breast Cancer Study
    Qiuyin Cai
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232, USA
    Cancer Epidemiol Biomarkers Prev 12:853-9. 2003
    ..No apparent synergetic effect of these two polymorphisms was identified. Results of this study indicate that genetic polymorphisms in the ER-alpha gene may play a role in the etiology of breast cancer...
  34. pmc Fruit and vegetable intakes are associated with lower risk of colorectal adenomas
    Huiyun Wu
    Department of Biostatistics and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
    J Nutr 139:340-4. 2009
    ..74 (95% CI = 0.58-0.96) for green vegetables. This study provides additional evidence that high total fruit intake and certain fruit and vegetable intakes may be associated with a reduced risk of colorectal adenomas...
  35. pmc Plasma carotenoids, tocopherols, retinol and breast cancer risk: results from the Shanghai Women Health Study (SWHS)
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Breast Cancer Res Treat 117:381-9. 2009
    ..Our results do not support an overall protective effect of lipophilic antioxidants on breast cancer risk. The few inverse associations observed for subtype of carotenoids may need to be confirmed in future studies...
  36. pmc Drinking green tea modestly reduces breast cancer risk
    Martha J Shrubsole
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt School of Medicine, Nashville, TN 37232, USA
    J Nutr 139:310-6. 2009
    ..046). COMT rs4680 genotypes did not have a modifying effect on the association of green tea intake with breast cancer risk. Drinking green tea may be weakly associated with a decreased risk of breast cancer...
  37. ncbi request reprint Correlation of blood sex steroid hormones with body size, body fat distribution, and other known risk factors for breast cancer in post-menopausal Chinese women
    Sonia M Boyapati
    Division of General Internal Medicine, Department of Medicine, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    Cancer Causes Control 15:305-11. 2004
    ..The objective of this analysis is to evaluate the association between measures of body size, dietary macronutrient intake, and reproductive factors with levels of endogenous sex hormones among women living in Shanghai, China...
  38. ncbi request reprint Functional Ser326Cys polymorphism in the hOGG1 gene is not associated with breast cancer risk
    Qiuyin Cai
    Division of Internal Medicine and Public Health, Department of Medicine, Center for Health Services Research, Vanderbilt Ingram University Medical Center, Vanderbilt University, Nashville, Tennessee 37232 6838, USA
    Cancer Epidemiol Biomarkers Prev 15:403-4. 2006
  39. ncbi request reprint Synergistic effects of STK15 gene polymorphisms and endogenous estrogen exposure in the risk of breast cancer
    Qi Dai
    Vanderbilt Center for Health Services Research, 1215 21st Avenue South, Medical Center East, Suite 6000, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:2065-70. 2004
    ....
  40. ncbi request reprint Physical activity, body size, and estrogen metabolism in women
    Charles E Matthews
    Vanderbilt Ingram Cancer Center, Center for Health Services Research, Vanderbilt University Medical Center, Medical Center East, Suite 6100, Nashville, TN 37232 8300, USA
    Cancer Causes Control 15:473-81. 2004
    ..We examined these relationships in cross-sectional analyses of 157 North American and Chinese women...
  41. pmc Heritable variation of ERBB2 and breast cancer risk
    Joan P Breyer
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 0275, USA
    Cancer Epidemiol Biomarkers Prev 18:1252-8. 2009
    ..In contrast, we observed no association of ERBB2 single nucleotide polymorphism haplotypes with breast cancer predisposition...
  42. pmc Vitamin supplement use and risk for breast cancer: the Shanghai Breast Cancer Study
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, Vanderbilt University, Nashville, TN, USA
    Breast Cancer Res Treat 111:269-78. 2008
    ....
  43. pmc Relation of FGFR2 genetic polymorphisms to the association between oral contraceptive use and the risk of breast cancer in Chinese women
    Wang Hong Xu
    Department of Epidemiology, School of Public Health, Fudan University, 138 Yi Xue Yuan Road, Shanghai, 200032, People s Republic of China
    Am J Epidemiol 173:923-31. 2011
    ..These findings suggest that genetic variants in FGFR2 may modify the role of OC use in causing breast cancer in Chinese women...
  44. pmc Circulating carotenoids and risk of breast cancer: pooled analysis of eight prospective studies
    A Heather Eliassen
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 104:1905-16. 2012
    ..Most, but not all, past studies of circulating carotenoids and breast cancer have found an inverse association with at least one carotenoid, although the specific carotenoid has varied across studies...
  45. pmc A prospective study of dietary polyunsaturated fatty acids and colorectal cancer risk in Chinese women
    Harvey J Murff
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Cancer Epidemiol Biomarkers Prev 18:2283-91. 2009
    ..03). These results suggest that dietary PUFA and the ratio of n-6 to n-3 PUFA intake may be positively associated with colorectal cancer risk, and this association may be mediated in part through PGE(2) production...
  46. ncbi request reprint Associations of reproductive time events and intervals with breast cancer risk: a report from the Shanghai Breast Cancer Study
    Zhezhou Huang
    Division of Epidemiology Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN Department of Cancer Control and Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
    Int J Cancer 135:186-95. 2014
    ..These findings suggest that while reproductive time events and intervals play an important role in breast cancer etiology, contributions may differ by menopausal status and hormone receptor status of breast cancers. ..
  47. ncbi request reprint Soyfood intake and breast cancer survival: a followup of the Shanghai Breast Cancer Study
    Sonia M Boyapati
    Division of General Internal Medicine, Department of Medicine, Center for Health Service Research, Vanderbilt University, Medical Center East, Suite 6000, Nashville, TN 37232 8300, USA
    Breast Cancer Res Treat 92:11-7. 2005
    ..These data suggest that soyfoods do not have an adverse effect on breast cancer survival...
  48. pmc Association between biomarkers of obesity and risk of high-grade prostatic intraepithelial neoplasia and prostate cancer--evidence of effect modification by prostate size
    Jay H Fowke
    Vanderbilt University Medical Center, Division of Epidemiology, Nashville, TN 37203, United States
    Cancer Lett 328:345-52. 2013
    ..Our results suggest obesity advances prostate carcinogenesis, and that detection biases at prostate biopsy may explain past inconsistencies in the association between obesity and PC...
  49. ncbi request reprint Dietary calcium intake and breast cancer risk among Chinese women in Shanghai
    Sonia M Boyapati
    Division of General Internal Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
    Nutr Cancer 46:38-43. 2003
    ....
  50. pmc Urinary biomarkers of oxidative stress and breast cancer survival
    Sarah Nechuta
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Cancer Causes Control 25:701-7. 2014
    ..We conducted a nested case-control study in a prospective breast cancer survivor cohort to investigate systemic oxidative stress and survival...
  51. pmc A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma
    Todd L Edwards
    Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, TN, USA
    Cancer Prev Res (Phila) 5:855-63. 2012
    ..We also observed effect modification of the HPGD signal by NSAID exposure...
  52. ncbi request reprint Urinary excretion of phytoestrogens and risk of breast cancer among Chinese women in Shanghai
    Qi Dai
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 11:815-21. 2002
    ..No association was observed with citrus flavonoids. The results from this study suggest that high intake of certain phytoestrogens may reduce the risk of breast cancer...
  53. pmc Nutritional factors in relation to endometrial cancer: a report from a population-based case-control study in Shanghai, China
    Wang Hong Xu
    Department of Epidemiology, Fu Dan University School of Public Health, Shanghai, People s Republic of China
    Int J Cancer 120:1776-81. 2007
    ..Dietary fiber, retinol, beta-carotene, vitamin C, vitamin E, and vitamin supplementation may decrease the risk of endometrial cancer...
  54. pmc A study of transportability of an existing smoking status detection module across institutions
    Mei Liu
    Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, TN, USA
    AMIA Annu Symp Proc 2012:577-86. 2012
    ..Our results showed that the customized module achieved significantly higher F-measures at all levels of classification (i.e., sentence, document, patient) compared to the direct application of the cTAKES module to the Vanderbilt data...
  55. ncbi request reprint Expression patterns of the ATM gene in mammary tissues and their associations with breast cancer survival
    Chuanzhong Ye
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2587, USA
    Cancer 109:1729-35. 2007
    ..The ataxia-telangiectasia mutated (ATM) gene plays a critical role in cell-cycle arrest, apoptosis, and DNA repair. However, to date, no study has directly investigated the association between ATM gene expression and breast cancer survival...
  56. pmc Evaluation of the synergistic effect of insulin resistance and insulin-like growth factors on the risk of breast carcinoma
    Alecia Malin
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232 8300, USA
    Cancer 100:694-700. 2004
    ....
  57. ncbi request reprint Passive smoking and breast cancer risk among non-smoking Chinese women
    Martha J Shrubsole
    Department of Internal Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232 8300, USA
    Int J Cancer 110:605-9. 2004
    ..6, 95% confidence interval 1.0-2.4; p for trend = 0.02). This association warrants further investigation...
  58. ncbi request reprint Association of serum concentration of organochlorine pesticides with dietary intake and other lifestyle factors among urban Chinese women
    Sang Ah Lee
    Department of Medicine, Center for Health Services Research, and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Environ Int 33:157-63. 2007
    ..Our study suggests that dietary intake may be an important contributor of serum levels of OCPs in Chinese women...
  59. ncbi request reprint Occupations and breast cancer risk among Chinese women in urban Shanghai
    Kathleen M Gardner
    Department of Medicine, and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232 8300, USA
    Am J Ind Med 42:296-308. 2002
    ..Although, an elevated risk of breast cancer has been suggested for a number of occupations, many earlier studies were limited by selection biases, the incomplete assessment of job histories, and the inability to control for confounding...
  60. ncbi request reprint Extracting epidemiologic exposure and outcome terms from literature using machine learning approaches
    Yanxin Lu
    Department of Human Anatomy, Histology and Embryology, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China
    Int J Data Min Bioinform 6:447-59. 2012
    ..To evaluate the performance of the system, we manually constructed an annotated dataset. The system achieved the highest F-measure of 82.0% for extracting exposure terms, and 70% for extracting outcome terms...
  61. ncbi request reprint Consumption of animal foods, cooking methods, and risk of breast cancer
    Qi Dai
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 11:801-8. 2002
    ..This study also suggests that nonhydrogenated soybean oil, if not used in high-temperature cooking, may be associated with a reduced risk of breast cancer...
  62. pmc Oxidative stress measured by urine F2-isoprostane level is associated with prostate cancer
    Daniel A Barocas
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA
    J Urol 185:2102-7. 2011
    ..We studied the relationship between the level of F2-isoprostanes, a validated biomarker of oxidative stress, and prostate cancer and high grade prostatic intraepithelial neoplasia...
  63. pmc Extracting and integrating data from entire electronic health records for detecting colorectal cancer cases
    Hua Xu
    Department of Biomedical Informatics, Vanderbilt University, School of Medicine, Nashville, TN, USA
    AMIA Annu Symp Proc 2011:1564-72. 2011
    ..996 for document level concept identification, and 0.93 for patient level case detection...
  64. ncbi request reprint Joint effect of estrogen receptor beta sequence variants and endogenous estrogen exposure on breast cancer risk in Chinese women
    S Lilly Zheng
    Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Cancer Res 63:7624-9. 2003
    ..Our results are consistent with the hypothesis of a joint effect of estrogen receptor beta sequence variants and endogenous estrogen exposure on breast cancer risk...
  65. ncbi request reprint Joint effect of insulin-like growth factors and sex steroids on breast cancer risk
    Herbert Yu
    Yale University School of Medicine and Yale Cancer Center, New Haven, Connecticut 06520, USA
    Cancer Epidemiol Biomarkers Prev 12:1067-73. 2003
    ..In conclusion, the study suggests a possible synergy between IGF peptide hormone and sex steroid hormones, including both estrogen and androgen, in relation to breast cancer risk...
  66. ncbi request reprint Plasma sex steroid hormones and breast cancer risk in Chinese women
    Herbert Yu
    Department of Epidemiology and Public Health and Yale Cancer Center, Yale University School of Medicine, New Haven, CT 06520 8034, USA
    Int J Cancer 105:92-7. 2003
    ....
  67. ncbi request reprint Dietary factors and risk of colon cancer in Shanghai, China
    Brian C H Chiu
    Department of Preventive and Societal Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198 4350, USA
    Cancer Epidemiol Biomarkers Prev 12:201-8. 2003
    ..Our findings suggest that diets high in fruit and antioxidant vitamins that are common in plant foods reduce the risk of colon cancer, whereas diets high in red meat, eggs, and preserved foods increase the risk...
  68. ncbi request reprint Menstrual and reproductive factors and endometrial cancer risk: Results from a population-based case-control study in urban Shanghai
    Wang Hong Xu
    Department of Epidemiology, Shanghai Cancer Institute, Shanghai, Peoples Republic of China
    Int J Cancer 108:613-9. 2004
    ..Our study suggests that prolonged menstruation was related to an increased risk of endometrial cancer while pregnancy, including induced abortion, reduced the risk of endometrial cancer...
  69. pmc Body mass index and colon cancer risk in Chinese people: menopause as an effect modifier
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd EPS Suite 511, MSC 7240, Bethesda, MD 20892 7240, USA
    Eur J Cancer 42:84-90. 2006
    ..91) and 0.7 (95% CI 0.5-0.95), respectively. Our findings suggest that BMI predicts colon cancer risk in both genders. Among women, however, the risk is modified by menopause status, possibly through altered endogenous oestrogen levels...
  70. ncbi request reprint Insulin-like growth factors and breast cancer risk in Chinese women
    Herbert Yu
    Department of Epidemiology and Public Health and Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520 8034, USA
    Cancer Epidemiol Biomarkers Prev 11:705-12. 2002
    ..In contrast to the findings from several studies conducted in Caucasian women, we found that IGFBP-3 was positively associated with breast cancer risk in Chinese women...
  71. pmc Soya food intake and risk of endometrial cancer among Chinese women in Shanghai: population based case-control study
    Wang Hong Xu
    Department of Epidemiology, Shanghai Cancer Institute, 2200 Xie Tu Road 25, Shanghai 200032, China
    BMJ 328:1285. 2004
    ..To evaluate the association of intake of soya food, a rich source of phytoestrogens, with the risk of endometrial cancer...
  72. ncbi request reprint Commuting physical activity and risk of colon cancer in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Am J Epidemiol 160:860-7. 2004
    ..54 for men; OR = 7.42, 95% CI: 2.84, 10.01 for women). Our results suggest that regular and frequent physical activity over a long period of time protects from colon cancer and significantly modifies the body mass index-associated risk...
  73. ncbi request reprint Insulin-like growth factor-I, soy protein intake, and breast cancer risk
    Maureen Sanderson
    University of Texas Houston School of Public Health at Brownsville, 78520, USA
    Nutr Cancer 50:8-15. 2004
    ..Further studies are needed to confirm our finding and to understand the biological mechanisms of these potential interactions...
  74. ncbi request reprint Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types
    Amanda Ewart-Toland
    UCSF Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    Carcinogenesis 26:1368-73. 2005
    ..The data also underline the advantages of comparative association studies involving study populations from different ethnic groups for determination of disease risk...
  75. ncbi request reprint Dietary patterns and breast cancer risk in the shanghai breast cancer study
    Xiaohui Cui
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Cancer Epidemiol Biomarkers Prev 16:1443-8. 2007
    ..1-3.3; P(trend) = 0.03). Our findings indicate that a western diet increases breast cancer risk in postmenopausal Chinese women. They also suggest the value of quantifying aggregate risk for common combinations of foods...
  76. ncbi request reprint [Obesity at different ages and endometrial cancer risk factors in urban Shanghai, China]
    Wanghong Xu
    Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, China
    Zhonghua Liu Xing Bing Xue Za Zhi 23:347-51. 2002
    ..To study the relationship between obesity at different ages and the risk of endometrial cancer in urban Shanghai, China...
  77. ncbi request reprint Gender-specific association between iron status and the history of attempted suicide: implications for gender paradox of suicide behaviors
    Yanfeng Li
    Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, SC 29208, USA
    Prog Neuropsychopharmacol Biol Psychiatry 31:1429-35. 2007
    ..Iron deficiency (ID) has been linked with high impulsivity, and an increased risk of ID was reported among suicide attempters. We hypothesized that poor iron status might be prevalent among suicide attempters, who have high impulsivity...
  78. doi request reprint Overweight is associated with decreased cognitive functioning among school-age children and adolescents
    Yanfeng Li
    Department of Epidemiology and Biostatistics, The Arnold School of Public Health, University of South Carolina, South Carolina, USA
    Obesity (Silver Spring) 16:1809-15. 2008
    ..We examined the associations between academic performance (AP), cognitive functioning (CF), and increased BMI in a nationally representative sample of children...

Research Grants8

  1. Oxidative Stress, Antioxidants and Breast Cancer Risk
    Qi Dai; Fiscal Year: 2004
    ..In addition, we will also be able to expand our study to a larger scale if the results are promising. Findings from this study will have important public health implications in the primary prevention of breast cancer. ..
  2. Oxidative Stress, Antioxidants and Breast Cancer Risk
    Qi Dai; Fiscal Year: 2005
    ..In addition, we will also be able to expand our study to a larger scale if the results are promising. Findings from this study will have important public health implications in the primary prevention of breast cancer. ..
  3. Dietary Calcium and Magnesium, Genetics, and Colorectal Adenoma
    Qi Dai; Fiscal Year: 2009
    ....
  4. Personalized Prevention of Colorectal Cancer
    Chang Yu; Fiscal Year: 2010
    ....
  5. Oxidative Stress, Antioxidants and Breast Cancer Risk
    Qi Dai; Fiscal Year: 2006
    ..In addition, we will also be able to expand our study to a larger scale if the results are promising. Findings from this study will have important public health implications in the primary prevention of breast cancer. ..
  6. Oxidative Stress, Antioxidants and Breast Cancer Risk
    Qi Dai; Fiscal Year: 2007
    ..In addition, we will also be able to expand our study to a larger scale if the results are promising. Findings from this study will have important public health implications in the primary prevention of breast cancer. ..
  7. Dietary Calcium and Magnesium, Genetics, and Colorectal Adenoma
    Qi Dai; Fiscal Year: 2010
    ....