Sean P Collins

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc The role of the emergency department in acute heart failure clinical trials--enriching patient identification and enrollment
    Sean P Collins
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN 37232, USA
    Am Heart J 165:902-9. 2013
  2. pmc Early changes in clinical characteristics after emergency department therapy for acute heart failure syndromes: identifying patients who do not respond to standard therapy
    Sean P Collins
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN 47232, USA
    Heart Fail Rev 17:387-94. 2012
  3. pmc Is hospital admission for heart failure really necessary?: the role of the emergency department and observation unit in preventing hospitalization and rehospitalization
    Sean P Collins
    Vanderbilt University, Nashville, Tennessee 37232, USA
    J Am Coll Cardiol 61:121-6. 2013
  4. pmc Elevated urinary neutrophil gelatinase-associated lipocalcin after acute heart failure treatment is associated with worsening renal function and adverse events
    Sean P Collins
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN 47232, USA
    Eur J Heart Fail 14:1020-9. 2012
  5. pmc Bayesian adaptive trial design in acute heart failure syndromes: moving beyond the mega trial
    Sean P Collins
    Vanderbilt University, Department of Medicine, Nashville, TN 47232, USA
    Am Heart J 164:138-45. 2012
  6. pmc A comparison of criterion standard methods to diagnose acute heart failure
    Sean P Collins
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN 37232, USA
    Congest Heart Fail 18:262-71. 2012
  7. pmc Risk stratification in acute heart failure: rationale and design of the STRATIFY and DECIDE studies
    Sean P Collins
    Vanderbilt University, Nashville, TN, USA
    Am Heart J 164:825-34. 2012
  8. pmc Galectin 3 complements BNP in risk stratification in acute heart failure
    Gregory J Fermann
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 34267 0769, USA
    Biomarkers 17:706-13. 2012
  9. doi request reprint S3 detection as a diagnostic and prognostic aid in emergency department patients with acute dyspnea
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, OH 45267 0769, USA
    Ann Emerg Med 53:748-57. 2009
  10. pmc Low-risk acute heart failure patients: external validation of the Society of Chest Pain Center's recommendations
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267 0769, USA
    Crit Pathw Cardiol 8:99-103. 2009

Detail Information

Publications42

  1. pmc The role of the emergency department in acute heart failure clinical trials--enriching patient identification and enrollment
    Sean P Collins
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN 37232, USA
    Am Heart J 165:902-9. 2013
    ....
  2. pmc Early changes in clinical characteristics after emergency department therapy for acute heart failure syndromes: identifying patients who do not respond to standard therapy
    Sean P Collins
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN 47232, USA
    Heart Fail Rev 17:387-94. 2012
    ..Future clinical trials may need to consider targeting these patients, as they may be the most likely to benefit from experimental therapy...
  3. pmc Is hospital admission for heart failure really necessary?: the role of the emergency department and observation unit in preventing hospitalization and rehospitalization
    Sean P Collins
    Vanderbilt University, Nashville, Tennessee 37232, USA
    J Am Coll Cardiol 61:121-6. 2013
    ..It is the authors' strong assertion that now is the time for such a trial and that the results will be critically important if we are to effectively influence hospitalizations for HF in the near future...
  4. pmc Elevated urinary neutrophil gelatinase-associated lipocalcin after acute heart failure treatment is associated with worsening renal function and adverse events
    Sean P Collins
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN 47232, USA
    Eur J Heart Fail 14:1020-9. 2012
    ..We hypothesized that initial urinary neutrophil gelatinase-associated lipocalcin (NGAL) levels, and changes in urinary NGAL levels after initial ED AHF therapy, would be associated with WRF and adverse events...
  5. pmc Bayesian adaptive trial design in acute heart failure syndromes: moving beyond the mega trial
    Sean P Collins
    Vanderbilt University, Department of Medicine, Nashville, TN 47232, USA
    Am Heart J 164:138-45. 2012
    ..In this study, AHFS clinical researchers and biostatisticians with expertise and experience in designing "personalized medicine" trials describe the development of a Bayesian adaptive design for an emergency department-based AHFS trial...
  6. pmc A comparison of criterion standard methods to diagnose acute heart failure
    Sean P Collins
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN 37232, USA
    Congest Heart Fail 18:262-71. 2012
    ..Different criterion standards identify different patients from among those being evaluated for AHFS. Researchers should consider this when choosing between the various criterion standard approaches when evaluating new index tests...
  7. pmc Risk stratification in acute heart failure: rationale and design of the STRATIFY and DECIDE studies
    Sean P Collins
    Vanderbilt University, Nashville, TN, USA
    Am Heart J 164:825-34. 2012
    ..Methods for identifying patients that can be sent home early are lacking. Improving the physician's ability to identify and safely manage low-risk patients is essential to avoiding unnecessary use of hospital beds...
  8. pmc Galectin 3 complements BNP in risk stratification in acute heart failure
    Gregory J Fermann
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 34267 0769, USA
    Biomarkers 17:706-13. 2012
    ..Galectin 3 (G3) is a mediator of fibrosis and remodeling in heart failure...
  9. doi request reprint S3 detection as a diagnostic and prognostic aid in emergency department patients with acute dyspnea
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, OH 45267 0769, USA
    Ann Emerg Med 53:748-57. 2009
    ..This study evaluates the effect of an S3 captured by acoustic cardiography on emergency physician diagnostic accuracy and confidence in their diagnosis of acute decompensated heart failure, as well as the patient's prognosis...
  10. pmc Low-risk acute heart failure patients: external validation of the Society of Chest Pain Center's recommendations
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267 0769, USA
    Crit Pathw Cardiol 8:99-103. 2009
    ..The goal of this analysis was to report on the outcomes experienced by ED patients with AHFS who do not have any of these high-risk criteria...
  11. ncbi request reprint The combined utility of an S3 heart sound and B-type natriuretic peptide levels in emergency department patients with dyspnea
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
    J Card Fail 12:286-92. 2006
    ....
  12. pmc Predictors of regional variations in hospitalizations following emergency department visits for atrial fibrillation
    Tyler W Barrett
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee Electronic address
    Am J Cardiol 112:1410-6. 2013
    ....
  13. pmc International variations in the clinical, diagnostic, and treatment characteristics of emergency department patients with acute heart failure syndromes
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Eur J Heart Fail 12:1253-60. 2010
    ..We examine differences in the presentation and management of emergency department (ED) patients with dyspnoea from acute heart failure syndromes (AHFS) between the USA, Western Europe, and Eastern Europe...
  14. doi request reprint Disparity of care in the acute care of patients with heart failure
    Deborah B Diercks
    Department of Emergency Medicine, University of California at Davis, Davis, CA, USA
    Acad Emerg Med 18:15-21. 2011
    ....
  15. ncbi request reprint The burden of acute heart failure on U.S. emergency departments
    Alan B Storrow
    Department of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee Electronic address
    JACC Heart Fail 2:269-77. 2014
    ..The goal of this study was to examine 2006 to 2010 emergency department (ED) admission rates, hospital procedures, lengths of stay, and costs for acute heart failure (AHF)...
  16. doi request reprint Patients with acute heart failure in the emergency department: do they all need to be admitted?
    Peter S Pang
    Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Card Fail 18:900-3. 2012
    ..Although additional research is needed, strategies for lower risk patients can and should be initiated to safely discharge AHF patients from the ED...
  17. doi request reprint Design and rationale of the URGENT Dyspnea study: an international, multicenter, prospective study
    Peter S Pang
    Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Am J Ther 15:299-303. 2008
    ..URGENT Dyspnea (Ularitide Global Evaluation in Acute Decompensated Heart Failure) is a prospective multicenter study designed to address these issues...
  18. ncbi request reprint Emergency department observation of heart failure: preliminary analysis of safety and cost
    Alan B Storrow
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267 0769, USA
    Congest Heart Fail 11:68-72. 2005
    ..These findings need to be further evaluated in a randomized clinical trial...
  19. ncbi request reprint Standardized reporting criteria for studies evaluating suspected acute heart failure syndromes in the emergency department
    Alan B Storrow
    Vanderbilt University, Nashville, TN, USA
    J Am Coll Cardiol 60:822-32. 2012
    ..Based on existing recommendations and expert consensus, the authors present standardized reporting criteria to improve interpretability of research in this challenging cohort...
  20. ncbi request reprint The effect of treatment on the presence of abnormal heart sounds in emergency department patients with heart failure
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, OH 45267 0769, USA
    Am J Emerg Med 24:25-32. 2006
    ..We sought to assess the proportion of ED patients with an electronically detected S(3) or S(4), determine the relation of these heart sounds to heart failure (HF), and analyze how the proportion changes with ED treatment...
  21. doi request reprint Acute heart failure risk stratification: can we define low risk?
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati School of Medicine, Cincinnati, OH 45267, USA
    Heart Fail Clin 5:75-83, vii. 2009
    ..This article reviews the available literature and describes patient features that need to be accounted for in disposition decision-making...
  22. doi request reprint A proposal to standardize dyspnoea measurement in clinical trials of acute heart failure syndromes: the need for a uniform approach
    Peter S Pang
    Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Eur Heart J 29:816-24. 2008
    ..This proposed tool requires detailed validation but has face validity for the uniform assessment of dyspnoea...
  23. doi request reprint Utility of a bedside acoustic cardiographic model to predict elevated left ventricular filling pressure
    Sean P Collins
    University of Cincinnati, Department of Emergency Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0769, USA
    Emerg Med J 27:677-82. 2010
    ..This study evaluated this bedside acoustic cardiographic model against invasive measurements of LV filling pressure...
  24. ncbi request reprint Prevalence of negative chest radiography results in the emergency department patient with decompensated heart failure
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
    Ann Emerg Med 47:13-8. 2006
    ..This study determines the rate of negative chest radiography results in patients found to have disease and the potential contribution of negative findings to a diagnosis discordant with heart failure by an emergency physician...
  25. doi request reprint The role of the emergency department in the patient with acute heart failure
    Courtney Fay Horton
    Vanderbilt University Medical Center, 1313 21st Avenue S 703 Oxford House, Nashville, TN 37232 4700, USA
    Curr Cardiol Rep 15:365. 2013
    ..The aim of this review is to evaluate current strategies for diagnosis, treatment, and disposition of the ADHF patient in the ED while highlighting new approaches for treatment and disposition, and areas in need of additional research...
  26. doi request reprint Update on aldosterone antagonists use in heart failure with reduced left ventricular ejection fraction. Heart Failure Society of America Guidelines Committee
    Javed Butler
    Department of Medicine, Division of Cardiology, Emory University, Atlanta, GA, USA
    J Card Fail 18:265-81. 2012
    ..The efficacy of eplerenone in patients with mild HF symptoms translates into a unique opportunity to reduce morbidity and mortality earlier in the course of the disease...
  27. ncbi request reprint Evaluation of chest pain and heart failure in the emergency department: impact of multimarker strategies and B-type natriuretic peptide
    W Brian Gibler
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio, USA
    Rev Cardiovasc Med 4:S47-55. 2003
    ..This article reviews the use of cardiac biomarkers in the emergency department to evaluate acute coronary syndrome and congestive heart failure...
  28. doi request reprint Observation units in the management of acute heart failure syndromes
    Gregory J Fermann
    Department of Emergency Medicine, University of Cincinnati, PO Box 670769, Cincinnati, OH 45267, USA
    Curr Heart Fail Rep 7:125-33. 2010
    ..Patient education and coordination of outpatient care continues to be paramount in preventing early readmission in this patient population...
  29. pmc Rates of emergency department visits due to pneumonia in the United States, July 2006-June 2009
    Wesley H Self
    Department of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, TN
    Acad Emerg Med 20:957-60. 2013
    ..The aim of this study was to quantify pneumonia-attributable ED visits in the United States among children and adults during the 3-year period July 2006 through June 2009...
  30. pmc Low numeracy is associated with increased odds of 30-day emergency department or hospital recidivism for patients with acute heart failure
    Candace D McNaughton
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Circ Heart Fail 6:40-6. 2013
    ..More than 25% of Medicare patients hospitalized for heart failure are readmitted within 30 days. The contributions of numeracy and health literacy to recidivism for patients with acute heart failure (AHF) are not known...
  31. ncbi request reprint Prevalence of the third and fourth heart sound in asymptomatic adults
    Sean P Collins
    Department of Emergency Medicine, and the Institute of Health Policy and Health Sciences Research, University of Cincinnati, Cincinnati, OH 45267, USA
    Congest Heart Fail 11:242-7. 2005
    ..04; 95% CI, 1.03-1.05). We conclude that the prevalence of an S3 is increased earlier in life, that an S4 is less common than previous studies suggest, and that its detection, even in the elderly, should not be ignored...
  32. doi request reprint Cost-effectiveness analysis of ED decision making in patients with non-high-risk heart failure
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
    Am J Emerg Med 27:293-302. 2009
    ..The ED disposition of patients with non-high-risk acute decompensated heart failure (ADHF) is challenging. To help address this problem, we investigated the cost-effectiveness of different ED disposition strategies...
  33. ncbi request reprint The third heart sound for diagnosis of acute heart failure
    Michael Johnston
    Vanderbilt University Medical Center, 703 Oxford House, 1313 21st Avenue, South, Nashville, TN 37232 4700, USA
    Curr Heart Fail Rep 4:164-8. 2007
    ..Data using these technologies and their applications in the ED are reviewed as well as implications for future use and research...
  34. ncbi request reprint Critical review and recommendations for nesiritide use in the emergency department
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0769, USA
    J Emerg Med 29:317-29. 2005
    ..We discuss these trials' results, suggest their relationship to the ED population, and provide recommendations for appropriate ED use...
  35. pmc Transient and sustained changes in operational performance, patient evaluation, and medication administration during electronic health record implementation in the emergency department
    Michael J Ward
    Department of Emergency Medicine, Vanderbilt University, Nashville, TN Electronic address
    Ann Emerg Med 63:320-8. 2014
    ..We quantify how the implementation of a comprehensive electronic health record was associated with metrics of operational performance, test ordering, and medication administration at a single-center ED...
  36. pmc Initial management of patients with acute heart failure
    Gregory J Fermann
    Department of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, ML 0769, Cincinnati, OH 45267, USA
    Heart Fail Clin 9:291-301, vi. 2013
    ..The risk stratification of patients is the subject of ongoing evaluation. The disposition of patients to areas other than a monitored inpatient bed, such as an emergency department-based observation unit, may prove effective. ..
  37. ncbi request reprint Diagnostic and prognostic usefulness of natriuretic peptides in emergency department patients with dyspnea
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Ann Emerg Med 41:532-45. 2003
    ..This article discusses each of the natriuretic peptides and attempts to delineate their potential diagnostic and prognostic roles in the ED...
  38. doi request reprint Risk stratification and short-term prognosis in acute heart failure syndromes: a review of novel biomarkers
    Ariadne Avellino
    Department of Emergency Medicine, University of Cincinnati, Ohio, USA
    Biomarkers 16:379-92. 2011
    ..Early risk stratification of patients with acute heart failure syndrome (AHFS) can guide the decision to admit the patient to hospital and the choice of therapy...
  39. ncbi request reprint The use of noninvasive ventilation in emergency department patients with acute cardiogenic pulmonary edema: a systematic review
    Sean P Collins
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267 0769, USA
    Ann Emerg Med 48:260-9, 269.e1-4. 2006
    ..We critically evaluate the evidence for the use of noninvasive ventilation on rates of hospital mortality and endotracheal intubation...
  40. ncbi request reprint Cost analysis of strategies to reduce blood culture contamination in the emergency department: sterile collection kits and phlebotomy teams
    Wesley H Self
    Department of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
    Infect Control Hosp Epidemiol 35:1021-8. 2014
    ..In addition to improving quality, implementing a sterile collection kit or phlebotomy team strategy is likely to result in net cost savings. ..
  41. ncbi request reprint Assessment of stroke index using impedance cardiography: comparison with traditional vital signs for detection of moderate acute blood loss in healthy volunteers
    Joshua M Kosowsky
    Department of Emergency Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Acad Emerg Med 9:775-80. 2002
    ....
  42. pmc Vereckei criteria used as a diagnostic tool by emergency medicine residents to distinguish between ventricular tachycardia and supra-ventricular tachycardia with aberrancy
    Rupen P Baxi
    Department of Emergency Medicine, University of Cincinnati College of Medicine, USA
    J Cardiol 59:307-12. 2012
    ..Accurate electrocardiographic (ECG) differentiation of ventricular tachycardia (VT) from supraventricular tachycardia with aberrancy (SVT-A) on ECG is key to therapeutic decision-making in the emergency department (ED) setting...