P David Charles

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Depression and intelligence in patients with Parkinson's disease and deep-brain stimulation
    Courtney R Schadt
    School of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212 3375, USA
    J Natl Med Assoc 98:1121-5. 2006
  2. doi request reprint Discordance in informed consent response on the basis of demographic factors: brief report
    Karen R Nunez-Wallace
    Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA
    Intellect Dev Disabil 48:175-9. 2010
  3. doi request reprint Pilot study assessing the feasibility of applying bilateral subthalamic nucleus deep brain stimulation in very early stage Parkinson's disease: study design and rationale
    David Charles
    Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
    J Parkinsons Dis 2:215-23. 2012
  4. pmc Continuation of long-term care for cervical dystonia at an academic movement disorders clinic
    Chandler E Gill
    Loyola University, Stritch School of Medicine, 2160 First Avenue South, Maywood, IL 60153, USA
    Toxins (Basel) 5:776-83. 2013
  5. ncbi request reprint Efficacy, tolerability, and immunogenicity of onabotulinumtoxina in a randomized, double-blind, placebo-controlled trial for cervical dystonia
    David Charles
    Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Clin Neuropharmacol 35:208-14. 2012
  6. pmc Deep brain stimulation in early Parkinson's disease: enrollment experience from a pilot trial
    P D Charles
    Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Parkinsonism Relat Disord 18:268-73. 2012
  7. ncbi request reprint Botulinum neurotoxin serotype A: a clinical update on non-cosmetic uses
    P David Charles
    Movement Disorders Clinic, Vanderbilt University, Nashville, TN, USA
    Am J Health Syst Pharm 61:S11-23. 2004
  8. doi request reprint Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability
    P David Charles
    Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2551, USA
    Mov Disord 25:466-73. 2010
  9. ncbi request reprint Spasticity in adults living in a developmental center
    Alyssa A Pfister
    Division of Movement Disorders, Dept of Neurology, Vanderbilt University Medical Center, 2100 Pierce Avenue, Nashville, TN 37212 3375, USA
    Arch Phys Med Rehabil 84:1808-12. 2003
  10. ncbi request reprint Deep brain stimulation of the subthalamic nucleus reduces antiparkinsonian medication costs
    P David Charles
    The Movement Disorders Clinic, Department of Neurology, Vanderbilt University Medical Center, 2100 Pierce Avenue, Suite 352 MCS, Vanderbilt University, Nashville, TN 37212 3375, USA
    Parkinsonism Relat Disord 10:475-9. 2004

Collaborators

Detail Information

Publications29

  1. pmc Depression and intelligence in patients with Parkinson's disease and deep-brain stimulation
    Courtney R Schadt
    School of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212 3375, USA
    J Natl Med Assoc 98:1121-5. 2006
    ..These findings suggest that Parkinson's disease patients with lower intelligence test scores and less education benefit more with regards to depressive symptomatology after STN-DBS than patients with higher scores and education...
  2. doi request reprint Discordance in informed consent response on the basis of demographic factors: brief report
    Karen R Nunez-Wallace
    Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA
    Intellect Dev Disabil 48:175-9. 2010
    ..This report highlights disparities in surrogate consent giving for individuals with intellectual disabilities and indicates a need for more research to ensure that this vulnerable population has access to appropriate treatments...
  3. doi request reprint Pilot study assessing the feasibility of applying bilateral subthalamic nucleus deep brain stimulation in very early stage Parkinson's disease: study design and rationale
    David Charles
    Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
    J Parkinsons Dis 2:215-23. 2012
    ..Preliminary evidence suggests that subthalamic nucleus stimulation may also be efficacious in early Parkinson's disease, and results of animal studies suggest that it may spare dopaminergic neurons in the substantia nigra...
  4. pmc Continuation of long-term care for cervical dystonia at an academic movement disorders clinic
    Chandler E Gill
    Loyola University, Stritch School of Medicine, 2160 First Avenue South, Maywood, IL 60153, USA
    Toxins (Basel) 5:776-83. 2013
    ....
  5. ncbi request reprint Efficacy, tolerability, and immunogenicity of onabotulinumtoxina in a randomized, double-blind, placebo-controlled trial for cervical dystonia
    David Charles
    Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Clin Neuropharmacol 35:208-14. 2012
    ..To evaluate the efficacy, tolerability, and neutralizing antibodies in the treatment of cervical dystonia with onabotulinumtoxinA (BOTOX)...
  6. pmc Deep brain stimulation in early Parkinson's disease: enrollment experience from a pilot trial
    P D Charles
    Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Parkinsonism Relat Disord 18:268-73. 2012
    ..DBS has not been studied in the early stages of PD, but early application should be explored to evaluate safety, efficacy, and the potential to alter disease progression...
  7. ncbi request reprint Botulinum neurotoxin serotype A: a clinical update on non-cosmetic uses
    P David Charles
    Movement Disorders Clinic, Vanderbilt University, Nashville, TN, USA
    Am J Health Syst Pharm 61:S11-23. 2004
    ....
  8. doi request reprint Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability
    P David Charles
    Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2551, USA
    Mov Disord 25:466-73. 2010
    ..0006). Transfers trended toward improvement (P = 0.053). This study shows comprehensive spasticity management provides meaningful improvement in ADL care for patients with ID, which may improve quality of life and reduce caregiver burden...
  9. ncbi request reprint Spasticity in adults living in a developmental center
    Alyssa A Pfister
    Division of Movement Disorders, Dept of Neurology, Vanderbilt University Medical Center, 2100 Pierce Avenue, Nashville, TN 37212 3375, USA
    Arch Phys Med Rehabil 84:1808-12. 2003
    ..To ascertain the prevalence of spasticity among adults living in a developmental center and to document the development of spasticity treatment plans for this population...
  10. ncbi request reprint Deep brain stimulation of the subthalamic nucleus reduces antiparkinsonian medication costs
    P David Charles
    The Movement Disorders Clinic, Department of Neurology, Vanderbilt University Medical Center, 2100 Pierce Avenue, Suite 352 MCS, Vanderbilt University, Nashville, TN 37212 3375, USA
    Parkinsonism Relat Disord 10:475-9. 2004
    ..DBS patients may experience a significant long-term reduction in the cost of their pharmacologic treatment...
  11. ncbi request reprint Botulinum toxin type A therapy during pregnancy
    William J Newman
    School of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37212 3375, USA
    Mov Disord 19:1384-5. 2004
    ..We present the first case report of clinical Botox treatment during pregnancy. This patient underwent four apparently uncomplicated full-term pregnancies while receiving regular Botox treatments...
  12. pmc Deep brain stimulation for early-stage Parkinson's disease: an illustrative case
    Chandler E Gill
    Stritch School of Medicine, Loyola University, Maywood, IL, USA
    Neuromodulation 14:515-21; discussion 521-2. 2011
    ..We are conducting a randomized pilot trial investigating DBS in early PD. This report describes one participant who received bilateral STN-DBS...
  13. doi request reprint Surgical targets for dystonic tremor: considerations between the globus pallidus and ventral intermediate thalamic nucleus
    Peter Hedera
    Department of Neurology, Vanderbilt University, Nashville, TN, USA
    Parkinsonism Relat Disord 19:684-6. 2013
    ..We propose that the patients with DT with a mild dystonia should be considered for Vim DBS procedure and the coexistence of severe DT and dystonia may be successfully controlled by combined GPi and Vim DBS surgeries...
  14. pmc Clustering of dystonia in some pedigrees with autosomal dominant essential tremor suggests the existence of a distinct subtype of essential tremor
    Peter Hedera
    Department of Neurology, Vanderbilt University, Nashville, TN 37232 8552, USA
    BMC Neurol 10:66. 2010
    ..Many patients with clinically definite ET develop dystonia. It remains unknown whether tremor associated with dystonia represent a subtype of ET. We hypothesized that ET with dystonia represents a distinct subtype of ET...
  15. pmc Deep brain stimulation in early stage Parkinson's disease: operative experience from a prospective randomised clinical trial
    Elyne Kahn
    School of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    J Neurol Neurosurg Psychiatry 83:164-70. 2012
    ..A randomised, prospective study is underway to determine whether STN-DBS in early PD is safe and tolerable...
  16. ncbi request reprint Thalamotomy, DBS-Vim, and DBS-GPi for generalized dystonia: a case report
    Courtney R Schadt
    Vanderbilt University School of Medicine, Nashville, TN 37212 3375, USA
    Tenn Med 100:38-9. 2007
    ..His tremor and dystonic symptoms have dramatically improved through combining these surgical interventions...
  17. pmc Difficulty in securing treatment for degenerative hip disease in a patient with Down syndrome: the gap remains open
    Chandler E Gill
    Vanderbilt University Medical Center, 2100 Pierce Ave, Nashville, TN 37212 3375, USA
    J Natl Med Assoc 98:93-6. 2006
    ..Finally, we reiterate the surgeon general's call to eradicate preconceptions held in the medical community about the population of persons with mental retardation that result in similar failures to provide adequate care...
  18. ncbi request reprint Bilateral globus pallidus internus deep brain stimulation therapy for primary generalized dystonia
    Bimal B Padaliya
    Vanderbilt University School of Medicine, USA
    Tenn Med 97:317-8. 2004
    ..This report details the successful treatment of a DYT1-positive 13 year-old boy suffering from PGD...
  19. pmc Subthalamic nucleus neuronal firing rate increases with Parkinson's disease progression
    Michael S Remple
    Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA
    Mov Disord 26:1657-62. 2011
    ..The results suggest that neuronal firing in the subthalamic nucleus increases with Parkinson's disease progression...
  20. doi request reprint Positive family history of essential tremor influences the motor phenotype of Parkinson's disease
    Peter Hedera
    Department of Neurology, Vanderbilt University, Nashville, Tennessee 37232 8522, USA
    Mov Disord 24:2285-8. 2009
    ..83, P < 0.001). Tremor-dominant subtype of PD in patients with a positive family history of ET suggests that these patients have inherited a genetic susceptibility factor for tremor, which affects the motor phenotype of PD...
  21. ncbi request reprint Successful treatment of childhood spasticity secondary to cerebral palsy using Botox
    Chandler Gill
    Department of Neurology, Vanderbilt University Medical Center, Suite 304, Medical Center South, Nashville, TN 37212, USA
    Tenn Med 96:511-3. 2003
    ..Botox was used in conjunction with a specific physical therapy regimen in order to reach a functional goal of independent ambulation...
  22. ncbi request reprint Deep brain stimulation: a new treatment for Parkinson's disease
    Myrandele Damian
    Division of Movement Disorders, Department of Neurology, Vanderbilt University Medical Center, Medical Center South, 2100 Pierce Ave, Nashville, TN 37212, USA
    Tenn Med 96:33-5. 2003
    ..Levodopa responsiveness, disabling motor fluctuations and dyskinesias, cognition, and concurrent illness are major factors in identifying candidates who will receive the greatest benefit...
  23. doi request reprint FUS in familial essential tremor - the search for common causes is still on
    Peter Hedera
    Department of Neurology, Vanderbilt University, 465 21st Avenue South, 6140 MRB III, Nashville, TN 37232 8552, USA
    Parkinsonism Relat Disord 19:818-20. 2013
    ..We did not identify a single pathogenic mutation. Our data suggest that FUS mutations are a rare cause of familial ET. ..
  24. pmc Subthalamic nucleus deep brain stimulation impacts language in early Parkinson's disease
    Lara Phillips
    Department of Neurology, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 7:e42829. 2012
    ....
  25. pmc Rationale and design of a prospective study: Cervical Dystonia Patient Registry for Observation of OnaBotulinumtoxinA Efficacy (CD PROBE)
    Joseph Jankovic
    Baylor College of Medicine, Department of Neurology, Houston, TX, USA
    BMC Neurol 11:140. 2011
    ..Irvine, CA, USA). Methods and baseline demographics from an interim analysis are provided...
  26. ncbi request reprint Pharmacological treatment of disabling tremor
    Courtney R Schadt
    Vanderbilt University, School of Medicine, Nashville, TN, USA
    Expert Opin Pharmacother 6:419-28. 2005
    ..This article outlines the available pharmacological agents and treatment considerations for various disabling tremors, including essential tremor and Parkinson's disease...
  27. pmc The cost of medical education in an ambulatory neurology clinic
    Anna Abramovitch
    School of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    J Natl Med Assoc 97:1288-90. 2005
    ..78 per half-day clinic. Students spent an average of 49.9 minutes per half-day seeing patients in the absence of an attending physician, an opportunity cost to the clinic of $142.50 per student per half-day...
  28. ncbi request reprint Efficacy and safety of botulinum type A toxin (Dysport) in cervical dystonia: results of the first US randomized, double-blind, placebo-controlled study
    Daniel Truong
    The Parkinson s and Movement Disorders Institute, Fountain Valley, California 92708, USA
    Mov Disord 20:783-91. 2005
    ..These results confirm previous reports that Dysport (500 units) is safe, effective, and well-tolerated in patients with cervical dystonia...
  29. ncbi request reprint Comparison of botulinum neurotoxin preparations for the treatment of cervical dystonia
    Mary Ann Chapman
    Visage Communications, Inc, Mead, Washington, USA
    Clin Ther 29:1325-37. 2007
    ....