Research Topics
Genomes and Genes | Daniel B CampbellSummaryAffiliation: Vanderbilt University Country: USA Publications
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Publications
Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophreniaDaniel B Campbell
Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, USA
Biol Psychiatry 63:32-41. 2008..The central role of RGS4 in regulating signaling via Gi/o coupled neurotransmitter receptors led us to hypothesize that there may be RGS4 genotypes predictive of specific disease phenotypes and antipsychotic treatment responses...
Association of RGS2 and RGS5 variants with schizophrenia symptom severityDaniel B Campbell
Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA
Schizophr Res 101:67-75. 2008..3-1q31. Due to overlapping cellular functions and chromosomal proximity, we hypothesized that multiple RGS genes may contribute to schizophrenia severity and treatment responsiveness...
Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorderDaniel B Campbell
Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, USA
Autism Res 1:159-68. 2008..These data further support our hypothesis that genetic susceptibility impacting multiple components of the MET signaling pathway contributes to ASD risk...
Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditionsDaniel B Campbell
Vanderbilt University, 8114 MRB3, 465 21st Ave South, Nashville, TN 37232, USA
Pediatrics 123:1018-24. 2009....
Disruption of cerebral cortex MET signaling in autism spectrum disorderDaniel B Campbell
Department of Pharmacology, Vanderbilt University, Nashville, TN 37203, USA
Ann Neurol 62:243-50. 2007..Here we examined expression levels of MET and members of the MET signaling pathway in postmortem cerebral cortex from ASD cases and healthy control subjects...
Association of MET with social and communication phenotypes in individuals with autism spectrum disorderDaniel B Campbell
Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA
Am J Med Genet B Neuropsychiatr Genet 153:438-46. 2010..These data indicate that the MET C allele influences at least two of the three domains of the autism triad...
A genetic variant that disrupts MET transcription is associated with autismDaniel B Campbell
Department of Pharmacology, Vanderbilt Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, TN 37203, USA
Proc Natl Acad Sci U S A 103:16834-9. 2006..These data implicate reduced MET gene expression in autism susceptibility, providing evidence of a previously undescribed pathophysiological basis for this behaviorally and medically complex disorder...
The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disordersPat Levitt
Vanderbilt Kennedy Center for Research on Human Development and Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
J Clin Invest 119:747-54. 2009....
Dynamic gene and protein expression patterns of the autism-associated met receptor tyrosine kinase in the developing mouse forebrainMatthew C Judson
Graduate Program in Neuroscience, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA
J Comp Neurol 513:511-31. 2009..Collectively, these data suggest that Met signaling may be necessary for the appropriate wiring of forebrain circuits, with particular relevance to the social and emotional dimensions of behavior...
Future of individualized psychiatric treatmentDaniel B Campbell
Pharmacogenomics 9:493-5. 2008
Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunctionElizabeth M Powell
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
J Neurosci 23:622-31. 2003....
