Hui Cai

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint Sources of variation in nutrient intakes among men in Shanghai, China
    Hui Cai
    Department of Medicine, Center for Health Services Research and Vanderbilt Ingram Cancer Center, 6009 MCE, Vanderbilt University, 1215 21st Avenue, Nashville, TN 37232 8300, USA
    Public Health Nutr 8:1293-9. 2005
  2. pmc Association of genetic polymorphisms in cell-cycle control genes and susceptibility to endometrial cancer among Chinese women
    Hui Cai
    Vanderbilt Epidemiology Center, Vanderbilt University, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Am J Epidemiol 173:1263-71. 2011
  3. ncbi request reprint Dietary patterns and their correlates among middle-aged and elderly Chinese men: a report from the Shanghai Men's Health Study
    Hui Cai
    Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232 8300, USA
    Br J Nutr 98:1006-13. 2007
  4. ncbi request reprint A prospective study of dietary patterns and mortality in Chinese women
    Hui Cai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashvill, TN, USA
    Epidemiology 18:393-401. 2007
  5. pmc Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women
    Hui Cai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Pharmacogenet Genomics 18:657-64. 2008
  6. pmc Dietary patterns and blood pressure among middle-aged and elderly Chinese men in Shanghai
    Sang Ah Lee
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, 2525 West End Avenue, Suite 600, IMPH, Nashville TN 37203 1738, USA
    Br J Nutr 104:265-75. 2010
  7. ncbi request reprint Association of endometrial cancer risk with a functional polymorphism (Asp(327)Asn) in the sex hormone-binding globulin gene
    Nobuhiko Kataoka
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, Tennessee, USA
    Cancer 109:1296-302. 2007
  8. pmc Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself
    Tsogzolmaa Dorjgochoo
    Divisions of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Clin Nutr 96:405-14. 2012
  9. pmc Prevalence and determinants of metabolic syndrome according to three definitions in middle-aged Chinese men
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
    Metab Syndr Relat Disord 7:37-45. 2009
  10. pmc Dietary carbohydrates, fiber, and breast cancer risk in Chinese women
    Wanqing Wen
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:283-9. 2009

Collaborators

Detail Information

Publications98

  1. ncbi request reprint Sources of variation in nutrient intakes among men in Shanghai, China
    Hui Cai
    Department of Medicine, Center for Health Services Research and Vanderbilt Ingram Cancer Center, 6009 MCE, Vanderbilt University, 1215 21st Avenue, Nashville, TN 37232 8300, USA
    Public Health Nutr 8:1293-9. 2005
    ....
  2. pmc Association of genetic polymorphisms in cell-cycle control genes and susceptibility to endometrial cancer among Chinese women
    Hui Cai
    Vanderbilt Epidemiology Center, Vanderbilt University, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Am J Epidemiol 173:1263-71. 2011
    ..73, 95% CI: 0.56, 0.94) without adjustment for multiple comparisons, significantly increased promoter activity. These findings suggest that polymorphisms of the CDKN1B gene may play a role in endometrial carcinogenesis...
  3. ncbi request reprint Dietary patterns and their correlates among middle-aged and elderly Chinese men: a report from the Shanghai Men's Health Study
    Hui Cai
    Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232 8300, USA
    Br J Nutr 98:1006-13. 2007
    ..Future studies of diet and health in this population will need to carefully take into account these potential confounders...
  4. ncbi request reprint A prospective study of dietary patterns and mortality in Chinese women
    Hui Cai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashvill, TN, USA
    Epidemiology 18:393-401. 2007
    ..Our study prospectively examines the relationship of dietary patterns with total mortality and cause-specific mortality in a population-based cohort study of Chinese women...
  5. pmc Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women
    Hui Cai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Pharmacogenet Genomics 18:657-64. 2008
    ..We investigated the associations of genetic polymorphisms in CYP19A1, a critical gene involved in estrogen synthesis, with plasma levels of sex hormones among postmenopausal Chinese women...
  6. pmc Dietary patterns and blood pressure among middle-aged and elderly Chinese men in Shanghai
    Sang Ah Lee
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, 2525 West End Avenue, Suite 600, IMPH, Nashville TN 37203 1738, USA
    Br J Nutr 104:265-75. 2010
    ..Results of the present study suggest an important role for diet in the prevention of hypertension...
  7. ncbi request reprint Association of endometrial cancer risk with a functional polymorphism (Asp(327)Asn) in the sex hormone-binding globulin gene
    Nobuhiko Kataoka
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, Tennessee, USA
    Cancer 109:1296-302. 2007
    ....
  8. pmc Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself
    Tsogzolmaa Dorjgochoo
    Divisions of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Clin Nutr 96:405-14. 2012
    ..There is limited literature on the contributors to isoprostane metabolite 2,3-dinor-5,6-dihydro-15-F(2t)-isoprostane (15-F(2t)-IsoP-M) compared with F(2)-isoprostanes (F(2)-IsoPs) as an oxidative stress biomarker...
  9. pmc Prevalence and determinants of metabolic syndrome according to three definitions in middle-aged Chinese men
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
    Metab Syndr Relat Disord 7:37-45. 2009
    ..We estimated the prevalence and lifestyle risk factors of metabolic syndrome according to three definitions of metabolic syndrome in urban Chinese men participating in the Shanghai Men's Health Study (SMHS)...
  10. pmc Dietary carbohydrates, fiber, and breast cancer risk in Chinese women
    Wanqing Wen
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:283-9. 2009
    ..Few studies have investigated the association of dietary carbohydrate and fiber intake with breast cancer risk in women in China, where carbohydrate intake is traditionally high...
  11. doi request reprint Dietary iron intake and risk of endometrial cancer: a population-based case-control study in Shanghai, China
    Asha R Kallianpur
    Institute for Medicine and Public Health, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37203 1738, USA
    Nutr Cancer 62:40-50. 2010
    ..Animal-derived iron intake is associated with increased risk of EC after menopause and among obese women. Avoidance of animal-derived (heme) iron may reduce the risk of EC in these women...
  12. ncbi request reprint Genetic polymorphisms in estrogen-metabolizing genes and breast cancer survival
    Ji Rong Long
    Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 1161 21st Avenue South, S 1121 Medical Center North, Nashville, TN 37232, USA
    Pharmacogenet Genomics 17:331-8. 2007
    ..The objective of the study is to investigate associations of breast cancer survival with genetic polymorphisms in several genes involved in estrogen metabolism (CYP1A1, CYP1A2, CYP1B1, COMT, and AhR)...
  13. ncbi request reprint Association of breast cancer risk with a common functional polymorphism (Asp327Asn) in the sex hormone-binding globulin gene
    Yong Cui
    Vanderbilt University Center for Health Services Research, 6th Floor, Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 14:1096-101. 2005
    ..05). This study suggests that the Asn allele in the SHBG gene may be related to a reduced risk of breast cancer among postmenopausal women by increasing their blood SHBG levels...
  14. pmc Intakes of fruits, vegetables, and related vitamins and lung cancer risk: results from the Shanghai Men's Health Study (2002-2009)
    Yumie Takata
    Vanderbilt Epidemiology Center, Vanderbilt University, Nashville, Tennessee, USA
    Nutr Cancer 65:51-61. 2013
    ..44-0.88), and 0.64 (0.46-0.88). Intake of all fruits and vegetables combined was marginally associated with lower risk. Our study suggests that the consumption of carotenoid-rich vegetables is inversely associated with lung cancer risk...
  15. pmc Prospective cohort study of soy food intake and colorectal cancer risk in women
    Gong Yang
    Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:577-83. 2009
    ..Data from epidemiologic studies linking usual soy food intake with colorectal cancer are limited and inconsistent...
  16. pmc Dietary and lifestyle predictors of age at natural menopause and reproductive span in the Shanghai Women's Health Study
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, Vanderbilt University and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Menopause 15:924-33. 2008
    ..We evaluated the impact of dietary, lifestyle and reproductive factors on age at natural menopause and reproductive span in Chinese women...
  17. pmc Fruit and vegetable intake and the risk of colorectal cancer: results from the Shanghai Men's Health Study
    Emily Vogtmann
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA
    Cancer Causes Control 24:1935-45. 2013
    ..Therefore, we aimed to evaluate the association of fruit and vegetable consumption with the risk of colorectal cancer among Chinese men...
  18. pmc Nonexercise physical activity and inflammatory and oxidative stress markers in women
    Sheng Hui Wu
    1 Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
    J Womens Health (Larchmt) 23:159-67. 2014
    ..Leisure time exercise has been linked to lower circulating levels of inflammatory markers. Few studies have examined the association of nonexercise physical activity with markers of inflammation and oxidative stress...
  19. pmc Intake of specific nonfermented soy foods may be inversely associated with risk of distal gastric cancer in a Chinese population
    Sun Seog Kweon
    Division of Epidemiology, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN
    J Nutr 143:1736-42. 2013
    ....
  20. pmc Fish intake and risks of total and cause-specific mortality in 2 population-based cohort studies of 134,296 men and women
    Yumie Takata
    Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525West End, Suite 600 Institute for Medicine and Public Health, Nashville, TN 37203, USA
    Am J Epidemiol 178:46-57. 2013
    ..Overall, our findings support the postulated health benefits of fish consumption. ..
  21. pmc Prediagnosis soy food consumption and lung cancer survival in women
    Gong Yang
    Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    J Clin Oncol 31:1548-53. 2013
    ..The effect size for aggressive lung cancers was larger than that observed for other types of lung cancer. Therefore, we hypothesized that soy consumption may favorably affect the overall survival of patients with lung cancer...
  22. pmc Associations of adult height and its components with mortality: a report from cohort studies of 135,000 Chinese women and men
    Na Wang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Epidemiol 40:1715-26. 2011
    ..Little is known about components of adult height in relation to mortality, particularly in developing countries...
  23. ncbi request reprint Population-based case-control study of AhR (aryl hydrocarbon receptor) and CYP1A2 polymorphisms and breast cancer risk
    Ji Rong Long
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, Nashville, TN 37232, USA
    Pharmacogenet Genomics 16:237-43. 2006
    ....
  24. pmc Prospective cohort study of tea consumption and risk of digestive system cancers: results from the Shanghai Women's Health Study
    Sarah Nechuta
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 96:1056-63. 2012
    ..In addition, to our knowledge, no study has investigated the association of tea consumption with the incidence of all digestive system cancers in Chinese women...
  25. pmc Soy food intake and circulating levels of inflammatory markers in Chinese women
    Sheng Hui Wu
    Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    J Acad Nutr Diet 112:996-1004, 1004.e1-4. 2012
    ..Soy and some of its constituents, such as isoflavones, have been shown to affect the inflammatory process in animal studies. The association between soy food intake and inflammatory markers has not been evaluated adequately in humans...
  26. pmc Replication study for reported SNP associations with breast cancer survival
    Alicia Beeghly-Fadiel
    Division of Epidemiology, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
    J Cancer Res Clin Oncol 138:1019-26. 2012
    ....
  27. pmc Association of obesity-related genetic variants with endometrial cancer risk: a report from the Shanghai Endometrial Cancer Genetics Study
    Ryan J Delahanty
    Vanderbilt Epidemiology Center, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Am J Epidemiol 174:1115-26. 2011
    ..The associations persisted after adjustment for BMI, suggesting that genetic markers of obesity provide value in addition to BMI in predicting endometrial cancer risk...
  28. pmc Red meat and poultry intakes and risk of total and cause-specific mortality: results from cohort studies of Chinese adults in Shanghai
    Yumie Takata
    Vanderbilt Epidemiology Center, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 8:e56963. 2013
    ..Further investigations are needed to elucidate the sex-specific associations between red meat intake and mortality...
  29. pmc Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women
    Raquel Villegas
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
    PLoS ONE 7:e49464. 2012
    ..The association was accentuated when we repeated analysis with the GRS2. In conclusion we found an association between GRS and lifestyle factors, alone and in combination, contributed to the risk of and T2D among middle age Chinese...
  30. pmc Soy food intake and risk of lung cancer: evidence from the Shanghai Women's Health Study and a meta-analysis
    Gong Yang
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, Nashville, TN 37203 1738, USA
    Am J Epidemiol 176:846-55. 2012
    ..This study suggests that soy food consumption may reduce lung cancer risk in nonsmoking women, particularly for aggressive tumors, and its effect may be modified by endogenous estrogens...
  31. pmc Circulating 25-hydroxyvitamin D levels in relation to blood pressure parameters and hypertension in the Shanghai Women's and Men's Health Studies
    Tsogzolmaa Dorjgochoo
    Division of Epidemiology, Department of Medicine and Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, IMPH, Nashville, TN 37203, USA
    Br J Nutr 108:449-58. 2012
    ..More research is needed to investigate the potential sex differential associations...
  32. pmc Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women's Health Study
    Sang Ah Lee
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:1920-6. 2009
    ..Soy food is a rich source of isoflavones--a class of phytoestrogens that has both antiestrogenic and anticarcinogenic properties...
  33. pmc Obesity, age, and oxidative stress in middle-aged and older women
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Ave, Nashville, TN 37203 1738, USA
    Antioxid Redox Signal 14:2453-60. 2011
    ..15-F(2t)-IsoP-M appears to be a valuable biomarker of oxidative stress in age- and obesity-related diseases...
  34. pmc Dietary calcium and magnesium intakes and the risk of type 2 diabetes: the Shanghai Women's Health Study
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:1059-67. 2009
    ..Diet plays a key role in the development of type 2 diabetes (T2D), but little is known about the contributions of specific nutrients in populations in which dietary patterns differ from Western populations...
  35. ncbi request reprint Abdominal adiposity and mortality in Chinese women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    Arch Intern Med 167:886-92. 2007
    ..Increased abdominal adiposity has been linked to an increase in mortality in populations where many are overweight or obese; it is unclear whether the same is true in relatively lean populations...
  36. ncbi request reprint Association of cyclin D1 genotype with breast cancer risk and survival
    Xiao Ou Shu
    Department of Medicine, Vanderbilt University Center for Health Services Research, 6th Floor, Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 14:91-7. 2005
    ..This study suggests that CCND1 A870G polymorphism may modify the postmenopausal breast cancer risk associated with hormonal exposure and predict survival after breast cancer diagnosis...
  37. pmc Association of a single nucleotide polymorphism at 6q25.1,rs2046210, with endometrial cancer risk among Chinese women
    Guoliang Li
    Division of Epidemiology and Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University School of Medicine and Vanderbilt Ingram Cancer Center, Nashville, Tennessee 37232, USA
    Chin J Cancer 30:138-43. 2011
    ..Our study suggests that rs2046210 may play a role in the etiology of endometrial cancer. Additional studies are needed to confirm our findings...
  38. pmc Fruit and vegetable consumption and risk of distal gastric cancer in the Shanghai Women's and Men's Health studies
    Meira Epplein
    Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Sixth Floor, Nashville, TN 37203, USA
    Am J Epidemiol 172:397-406. 2010
    ..67). No associations between dietary intakes of select antioxidant micronutrients were seen for men or women. Fruit intake is inversely associated with distal gastric cancer risk among men in Shanghai, China...
  39. pmc Genetic polymorphisms in the MMP-7 gene and breast cancer survival
    Alicia Beeghly-Fadiel
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Cancer 124:208-14. 2009
    ..9) and TT (OS HR: 0.3, 95% CI: 0.1-0.8) fared better than patients with AA (p-value for trend: 0.001). Thus, common MMP-7 genetic polymorphisms were found to be significant determinants of survival among Chinese women with breast cancer...
  40. pmc Association of genetic markers in the BCL-2 family of apoptosis-related genes with endometrial cancer risk in a Chinese population
    Tsogzolmaa Dorjgochoo
    Division of Epidemiology, Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 8:e60915. 2013
    ..The role of genetic variants in BCL-2 genes and their interactions with non-genetic factors in the development of endometrial cancer has not been investigated in epidemiological studies...
  41. pmc T'ai chi as exercise among middle-aged and elderly Chinese in urban China
    Gurjeet S Birdee
    Division of General Internal Medicine and Pediatrics, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    J Altern Complement Med 19:550-7. 2013
    ..T'ai chi is a form of mind-body practice used as exercise in China, though limited data are available on characteristics of t'ai chi users and factors associated with practice...
  42. ncbi request reprint Genetic polymorphisms in the IGFBP3 gene: association with breast cancer risk and blood IGFBP-3 protein levels among Chinese women
    Zefang Ren
    Department of Medicine, Vanderbilt University, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 13:1290-5. 2004
    ..05). These results indicated that IGFBP3 polymorphisms may be associated with the level of blood IGFBP-3 protein and an increased risk of breast cancer...
  43. pmc Genetic polymorphisms of metastasis suppressor gene NME1 and breast cancer survival
    Shimian Qu
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Clin Cancer Res 14:4787-93. 2008
    ....
  44. pmc Sleep duration and its correlates in middle-aged and elderly Chinese women: the Shanghai Women's Health Study
    Xiangdong Tu
    Vanderbilt Epidemiology Center, Department of Medicine and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Sleep Med 13:1138-45. 2012
    ..Abnormal sleep duration, either long or short, is associated with disease risk and mortality. Little information is available on sleep duration and its correlates among Chinese women...
  45. pmc Age at menarche, the leg length to sitting height ratio, and risk of diabetes in middle-aged and elderly Chinese men and women
    Baqiyyah N Conway
    Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 7:e30625. 2012
    ..To evaluate the associations of age at menarche and the leg length-to-sitting-height ratio, markers of adolescent growth, with risk of diabetes in later life...
  46. pmc Urinary polyphenols and breast cancer risk: results from the Shanghai Women's Health Study
    Jianfeng Luo
    Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Breast Cancer Res Treat 120:693-702. 2010
    ..In conclusion, high epicatechin may be related to a reduced risk of breast cancer. Further studies are warranted to confirm our findings...
  47. pmc Soy food intake and breast cancer survival
    Xiao Ou Shu
    Department of Medicine, Vanderbilt Epidemiology Center, 2525 West End Ave, Ste 600, Nashville, TN 37203 1738, USA
    JAMA 302:2437-43. 2009
    ..However, the estrogen-like effect of isoflavones and the potential interaction between isoflavones and tamoxifen have led to concern about soy food consumption among breast cancer patients...
  48. pmc Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Clin Nutr 94:240-6. 2011
    ..Asian populations habitually consume a large amount of cruciferous vegetables and other plant-based foods. Few epidemiologic investigations have evaluated the potential health effects of these foods in Asian populations...
  49. pmc Association of hormone-related characteristics and breast cancer risk by estrogen receptor/progesterone receptor status in the shanghai breast cancer study
    Ping Ping Bao
    Vanderbilt Epidemiology Center, Institute of Medicine and Public Health, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 600, Nashville, TN 37203 1738, USA
    Am J Epidemiol 174:661-71. 2011
    ..More research is needed to better understand the etiology of 2 relatively rare subtypes, ER+/PR- tumors and ER-/PR+ tumors...
  50. pmc Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study
    Qi Dai
    Department of Medicine and Pharmacology, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Nashville, TN 37203 1738, USA
    J Clin Oncol 27:2482-8. 2009
    ..No prospective study has investigated whether levels of 15-F(2t)-isoprostane (15-F(2t)-IsoP) and its metabolite 2,3-dinor-5,6-dihydro-15-F(2t)-IsoP (15-F(2t)-IsoPM) are related to breast cancer risk...
  51. pmc Resting heart rate and risk of type 2 diabetes in women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Int J Epidemiol 39:900-6. 2010
    ..Resting heart rate has been shown to predict risk of cardiovascular disease; its association with diabetes remains unclear, particularly in non-Western populations...
  52. ncbi request reprint Polymorphisms of the CYP1B1 gene may be associated with the onset of natural menopause in Chinese women
    Ji Rong Long
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, S 1108 Medical Center North, Nashville, TN 37232 2587, United States
    Maturitas 55:238-46. 2006
    ..6 fewer menstrual cycles than those women without this allele. In conclusion, the results from this study suggested that CYP1B1 genetic polymorphisms may be associated with the natural onset of menopause...
  53. pmc Postdiagnosis cruciferous vegetable consumption and breast cancer outcomes: a report from the After Breast Cancer Pooling Project
    Sarah Nechuta
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Cancer Epidemiol Biomarkers Prev 22:1451-6. 2013
    ..Our results do not support an association between postdiagnosis cruciferous vegetable intake and breast cancer outcomes...
  54. pmc Genetic polymorphisms in obesity-related genes and endometrial cancer risk
    Xiaoli Chen
    Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
    Cancer 118:3356-64. 2012
    ....
  55. pmc Urinary polyphenols, glutathione S-transferases copy number variation, and breast cancer risk: results from the Shanghai women's health study
    Jianfeng Luo
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203 1738, USA
    Mol Carcinog 51:379-88. 2012
    ..The differential associations between polyphenols and breast cancer risk by GST polymorphisms, if confirmed, may provide a new avenue for the personalized prevention of breast cancer...
  56. pmc Relation of blood pressure components and categories and all-cause, stroke and coronary heart disease mortality in urban Chinese women: a population-based prospective study
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
    J Hypertens 27:468-75. 2009
    ..To determine whether various levels of blood pressure (BP), particularly normal and high normal BP or prehypertension, predict cardiovascular mortality among urban Chinese women...
  57. pmc Fish, shellfish, and long-chain n-3 fatty acid consumption and risk of incident type 2 diabetes in middle-aged Chinese men and women
    Raquel Villegas
    Vanderbilt University Medical Center, Nashville, TN 37203, USA
    Am J Clin Nutr 94:543-51. 2011
    ..However, the role of long-chain n-3 fatty acids and fish intake in the development of T2D remains unresolved...
  58. pmc Intra-person variation of urinary biomarkers of oxidative stress and inflammation
    Xiaoyan Wu
    Division of Epidemiology, Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Cancer Epidemiol Biomarkers Prev 19:947-52. 2010
    ..However, little information is available regarding the intra-person variation of these biomarkers, hindering their application in epidemiologic studies...
  59. ncbi request reprint Physical activity and the incidence of type 2 diabetes in the Shanghai women's health study
    Raquel Villegas
    Department of Medicine, Vanderbilt Epidemiology Center Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Int J Epidemiol 35:1553-62. 2006
    ..The aim of this study was to examine the effect of occupational, commuting, daily living, and LPA on the incidence of type 2 diabetes in a cohort of middle-aged women...
  60. pmc Plasma carotenoids, tocopherols, retinol and breast cancer risk: results from the Shanghai Women Health Study (SWHS)
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Breast Cancer Res Treat 117:381-9. 2009
    ..Our results do not support an overall protective effect of lipophilic antioxidants on breast cancer risk. The few inverse associations observed for subtype of carotenoids may need to be confirmed in future studies...
  61. pmc A prospective study of dietary polyunsaturated fatty acids and colorectal cancer risk in Chinese women
    Harvey J Murff
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Cancer Epidemiol Biomarkers Prev 18:2283-91. 2009
    ..03). These results suggest that dietary PUFA and the ratio of n-6 to n-3 PUFA intake may be positively associated with colorectal cancer risk, and this association may be mediated in part through PGE(2) production...
  62. pmc Is green tea drinking associated with a later onset of breast cancer?
    Qi Dai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN 37203 1738, USA
    Ann Epidemiol 20:74-81. 2010
    ..Because of the substantial difference in levels of estrogens between premenopausal and postmenopausal women, the relationship between tea consumption and breast cancer risk may depend on menopausal status...
  63. pmc Comorbidities and breast cancer survival: a report from the Shanghai Breast Cancer Survival Study
    Sarah Nechuta
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Breast Cancer Res Treat 139:227-35. 2013
    ....
  64. ncbi request reprint MTHFR genotypes and breast cancer survival after surgery and chemotherapy: a report from the Shanghai Breast Cancer Study
    Martha J Shrubsole
    Department of Medicine, Division of Internal Medicine, Vanderbilt School of Medicine, Vanderbilt University, Nashville, TN 37232 2587, USA
    Breast Cancer Res Treat 91:73-9. 2005
    ..97, 95% CI: 1.10-7.98, p for trend=0.04). The A1298C genotypes were not significantly associated with risk of death. This study suggests that the MTHFR C677T polymorphisms may affect long-term survival from advanced breast cancer...
  65. pmc Energy balance and breast cancer risk
    Alecia Malin
    Department of Surgery, Meharry Medical College, 1005 Dr D B Todd Boulevard, Nashville, Tennessee 37208, USA
    Cancer Epidemiol Biomarkers Prev 14:1496-501. 2005
    ..74; 95% confidence interval, 2.05-12.20). Our study suggests that promotion of behavior patterns that optimize energy balance (weight control and increasing physical activity) may be a viable option for breast cancer prevention...
  66. pmc Novel genetic markers of breast cancer survival identified by a genome-wide association study
    Xiao Ou Shu
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
    Cancer Res 72:1182-9. 2012
    ..39 × 10(-7)). Similar associations were observed for these two SNPs with breast cancer-specific mortality. This study provides strong evidence suggesting that the RAD51L1 gene and a chromosome 16 locus influence breast cancer prognosis...
  67. pmc Dietary patterns are associated with lower incidence of type 2 diabetes in middle-aged women: the Shanghai Women's Health Study
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN, USA
    Int J Epidemiol 39:889-99. 2010
    ..Data linking risk of type 2 diabetes (T2D) and dietary patterns in Chinese populations are scarce...
  68. pmc Vitamin supplement use during breast cancer treatment and survival: a prospective cohort study
    Sarah Nechuta
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
    Cancer Epidemiol Biomarkers Prev 20:262-71. 2011
    ..We evaluated the association of vitamin supplement use in the first 6 months after breast cancer diagnosis and during cancer treatment with total mortality and recurrence...
  69. pmc Dietary B vitamin and methionine intakes and breast cancer risk among Chinese women
    Martha J Shrubsole
    Vanderbilt Epidemiology Center, Division of Epidemiology, Eighth Floor, Suite 800, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Am J Epidemiol 173:1171-82. 2011
    ..07, 2.46; P for trend = 0.04 for the highest vs. lowest quartile of intake). Findings support the hypothesis that high folate intake may reduce breast cancer risk and that the association may vary by menopausal and ER/PR status...
  70. ncbi request reprint Association of ginseng use with survival and quality of life among breast cancer patients
    Yong Cui
    Department of Medicine, Center for Health Services Research, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232 8300, USA
    Am J Epidemiol 163:645-53. 2006
    ..Additionally, QOL improved as cumulative ginseng use increased...
  71. ncbi request reprint ERBB2 genetic polymorphism and breast cancer risk in Chinese women: a population-based case-control study
    Shimian Qu
    Department of Medicine, Vanderbilt Epidemiology Center, Institute of Medicine and Public Health, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN 37203 1738, USA
    Breast Cancer Res Treat 110:169-76. 2008
    ..These study results suggest that Ile655Val polymorphism of the ERBB2 gene do not alter its activity and may not be associated with increased breast cancer risk among Chinese women...
  72. pmc Peroxisome proliferator-activated receptor delta (PPARD) genetic variation and type 2 diabetes in middle-aged Chinese women
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Nashville, TN 37203 1738, USA
    Ann Hum Genet 75:621-9. 2011
    ....
  73. pmc Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: a prospective cohort study
    Harvey J Murff
    Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Cancer 128:1434-41. 2011
    ..The relative amounts of n-6 PUFA to marine-derived n-3 PUFAs may be more important for breast cancer risk than individual dietary amounts of these fatty acids...
  74. ncbi request reprint Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma
    Zefang Ren
    Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA
    Cancer 101:251-7. 2004
    ..The authors investigated the association of breast carcinoma with genetic polymorphisms in the GH1 gene in the Shanghai Breast Cancer Study...
  75. pmc Vitamin supplement use and risk for breast cancer: the Shanghai Breast Cancer Study
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, Vanderbilt University, Nashville, TN, USA
    Breast Cancer Res Treat 111:269-78. 2008
    ....
  76. ncbi request reprint Validity and reproducibility of the food-frequency questionnaire used in the Shanghai men's health study
    Raquel Villegas
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Medical Center East, Suite 6000, 1215 21st Avenue South, Nashville, TN 37232 8300, USA
    Br J Nutr 97:993-1000. 2007
    ..8 and 49.2%, while misclassification to opposite quartiles was between 1.5 and 6.2%. These data indicate that the SMHS FFQ can reasonably categorise usual intake of nutrients and food groups among men living in urban Shanghai...
  77. ncbi request reprint The long-term impact of medical and socio-demographic factors on the quality of life of breast cancer survivors among Chinese women
    Yong Cui
    Department of Medicine, Center for Health Services Research and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232 8300, USA
    Breast Cancer Res Treat 87:135-47. 2004
    ....
  78. ncbi request reprint E-cadherin promoter polymorphisms are not associated with the aggressiveness of prostate cancer in Caucasian patients
    He Cheng Li
    Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Urol Oncol 24:496-502. 2006
    ..Decreased E-cadherin expression predicts poor outcome among patients with cancer. We sought to investigate whether -160C-->A and/or -347G-->GA polymorphisms were associated with the aggressiveness of prostate cancer...
  79. pmc Use of oral contraceptives, intrauterine devices and tubal sterilization and cancer risk in a large prospective study, from 1996 to 2006
    Tsogzolmaa Dorjgochoo
    Vanderbilt Epidemiology Center, Department of Medicine, School of Medicine, Vanderbilt University, Nashville, TN 37203 1738, USA
    Int J Cancer 124:2442-9. 2009
    ..Although chance findings are a likely explanation for some of the associations found in our study, these findings suggest that various contraceptive methods or reproductive patterns may play a role in the etiology of cancer...
  80. ncbi request reprint Genetic polymorphisms in the TGF-beta 1 gene and breast cancer survival: a report from the Shanghai Breast Cancer Study
    Xiao Ou Shu
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
    Cancer Res 64:836-9. 2004
    ..4, 95% confidence interval, 1.0-1.9). Our study suggests that genetic polymorphisms in the TGF-beta1 gene may play a role in breast cancer progression...
  81. ncbi request reprint Lithium treatment inhibits renal GSK-3 activity and promotes cyclooxygenase 2-dependent polyuria
    Reena Rao
    Div of Nephrology, Vanderbilt Univ Medical Ctr, S3223, MCN, Nashville, TN 37232, USA
    Am J Physiol Renal Physiol 288:F642-9. 2005
    ..In conclusion, these findings temporally link decreased GSK-3 activity to enhanced renal COX2 expression and COX2-derived urine PGE(2) excretion. Suppression of COX2-derived PGE(2) blunts lithium-associated polyuria...
  82. ncbi request reprint In utero exposure to female hormones and germ cell tumors in children
    Sadhna Shankar
    Department of Pediatrics and Vanderbilt University Center for Health Services Research, Nashville, Tennessee 37232, USA
    Cancer 106:1169-77. 2006
    ..Maternal exposure to exogenous female hormones during pregnancy has been implicated as a risk factor for malignant germ cell tumors (GCTs) in the offspring in some epidemiologic studies of testicular and ovarian carcinoma in adults...
  83. ncbi request reprint Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas
    Chuanzhong Ye
    Department of Medicine, Vanderbilt Ingram Cancer Center, Nashville, Tennessee, USA
    Oncol Rep 16:429-35. 2006
    ..The methylation status of these genes in rectal mucosa biopsies detected by MSP assays may not distinguish between patients with and without adenomas in the colon...
  84. ncbi request reprint High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease
    Valeriu Cebotaru
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Kidney Int 68:642-52. 2005
    ..Dent's disease results from mutations of the voltage-gated chloride channel CLC-5...
  85. ncbi request reprint Differentiation of cyclooxygenase 1- and 2-derived prostanoids in mouse kidney and aorta
    Zhonghua Qi
    Division of Nephrology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN 37232, USA
    Hypertension 48:323-8. 2006
    ..These effects may contribute to the specific effect of COX2 inhibitors to increase blood pressure...
  86. ncbi request reprint Regional expression of cyclooxygenase isoforms in the rat kidney in complete unilateral ureteral obstruction
    Shyan Yih Chou
    Department of Medicine, Brookdale University Hospital and Medical Center, Brooklyn, New York, USA
    J Urol 170:1403-8. 2003
    ..After the release of 24-hour UUO cortical vasoconstriction occurs but medullary hyperemia is seen. We examined the expression of the 2 COX isoforms COX-1 and COX-2 in different regions of the kidney in rats subjected to UUO...
  87. ncbi request reprint [Relationship between calpain-10 gene polymorphism, hypertension and plasma glucose]
    Jing Hong
    Department of Endocrinology, China Japan Friendship Hospital, Beijing 100029, China
    Zhonghua Nei Ke Za Zhi 41:370-3. 2002
    ..To detect the association among calpain-10(CAPN-10) gene polymorphism, hypentension and hyperglycemia...
  88. pmc Potential role for ADAM15 in pathological neovascularization in mice
    Keisuke Horiuchi
    Cellular Biochemistry and Biophysics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Mol Cell Biol 23:5614-24. 2003
    ..Since ADAM15 does not appear to be required for developmental angiogenesis or for adult homeostasis, it may represent a novel target for the design of inhibitors of pathological neovascularization...
  89. pmc Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life
    Gisela Weskamp
    Cellular Biochemistry and Biophysics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Mol Cell Biol 22:1537-44. 2002
    ....
  90. ncbi request reprint Impact of newly diagnosed breast cancer on quality of life among Chinese women
    Wei Lu
    Shanghai Center for Disease Control and Prevention, Shanghai, China
    Breast Cancer Res Treat 102:201-10. 2007
    ..Being diagnosed with breast cancer is a very stressful event that has a profound impact on multiple aspects of a patient's daily life. Little is known about the quality of life (QOL) of Chinese women with newly diagnosed breast cancer...
  91. doi request reprint Purine-containing cucurbitane triterpenoids from Cucurbita pepo cv dayangua
    Da Cheng Wang
    School of Veterinary Science, Jilin University, Jilin 130062, China
    Phytochemistry 69:1434-8. 2008
    ..Cucurbitaglycosides A and B showed cytotoxic activity against the human epithelial carcinoma cell line HeLa with IC50 of 17.2 and 28.4 microg/mL, respectively...
  92. ncbi request reprint Characterization of endogenous betaine gamma-amino-n-butyric acid cotransporter glycoform and its hyperosmotic regulation in MDCK cells
    Xue Mei Zhang
    Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China
    Pflugers Arch 454:143-53. 2007
    ..We conclude that BGAT is an N-glycosylated protein with two glycoforms and endogenous BGAT synthesis rather than processing is involved in the adaptation to the hyperosmotic stress...
  93. ncbi request reprint [Analysis on potential years of life lost of automobile drivers in Jiangsu in 1990 - 1999]
    Peng Cheng Xun
    Department of Medical Statistics, Nantong Medical College, Nantong 226001, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:284-7. 2003
    ..To describe the health status of automobile drivers and to define their potential years of life lost (PYLL) resulting from main death causes in Jiangsu in 1990 - 1999...
  94. ncbi request reprint Molecular and pathological characterization of two H5N1 avian influenza viruses isolated from wild ducks
    Junwei Li
    State Key Laboratory of Virology and Modern Virology Research Center, College of Life Sciences, Wuhan University, Luojia Hill, Wuhan 430072, People s Republic of China
    Virus Genes 37:88-95. 2008
    ..The results of present study with both H5N1 viruses also suggested that wild ducks may play an important role in maintaining circulation of H5N1 viruses...
  95. doi request reprint Native, oxidized lipoprotein(a) and lipoprotein(a) immune complex in patients with active and inactive rheumatoid arthritis: plasma concentrations and relationship to inflammation
    Junjun Wang
    Department of Biochemistry, Jinling Hospital, Clinical School of Medical College, Nanjing University, 305, East Zhong Shan Road, Nanjing, 210002, China
    Clin Chim Acta 390:67-71. 2008
    ..We investigated Lp(a), ox-Lp(a) and Lp(a)-IC concentrations in RA patients and to explore the relationships with inflammatory disease activity markers...
  96. ncbi request reprint Effect of ghrelin on human endothelial cells apoptosis induced by high glucose
    Hong Zhao
    Department of Endocrinology, First Hospital of China Medical University, Shenyang 110001, China
    Biochem Biophys Res Commun 362:677-81. 2007
    ..This peptide may have potential in preventing diabetic complications, especially in obese patients...
  97. ncbi request reprint ClC-5: role in endocytosis in the proximal tubule
    YingHong Wang
    Dept of Physiology, WBSB Rm 208, The Johns Hopkins Univ School of Medicine, 725 N Wolfe St, Baltimore, MD 21205, USA
    Am J Physiol Renal Physiol 289:F850-62. 2005
    ..Our data from the mutants suggest that defective targeting and trafficking of mutant ClC-5 to the endosomes are a major determinant in the lack of normal endocytosis in Dent's disease...
  98. pmc Endostatin polymorphism 4349G/A(D104N) is not associated with aggressiveness of disease in prostate [corrected] cancer
    He Cheng Li
    Department of Breast Surgery, Cancer Hospital Cancer Institute, Fudan University, Shanghai, 200032, PR China
    Dis Markers 21:37-41. 2005
    ..8283, 0.3713 respectively). We concluded that endostatin polymorphism was not associated with the aggressiveness of prostate cancer in Caucasian patients...