Joshua W Buckholtz

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. doi request reprint Psychopathology and the human connectome: toward a transdiagnostic model of risk for mental illness
    Joshua W Buckholtz
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Neuron 74:990-1004. 2012
  2. pmc Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits
    Joshua W Buckholtz
    Department of Psychology, Vanderbilt University, Nashville, Tennessee, USA
    Nat Neurosci 13:419-21. 2010
  3. pmc Dopaminergic network differences in human impulsivity
    Joshua W Buckholtz
    Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
    Science 329:532. 2010
  4. doi request reprint MAOA and the neurogenetic architecture of human aggression
    Joshua W Buckholtz
    Vanderbilt Brain Institute and Department of Psychology, Vanderbilt University, Nashville, TN 37212, USA
    Trends Neurosci 31:120-9. 2008
  5. pmc A thalamocorticostriatal dopamine network for psychostimulant-enhanced human cognitive flexibility
    Gregory R Samanez-Larkin
    Department of Psychology, Vanderbilt University, Nashville, Tennessee Institute of Imaging Science, Vanderbilt University, Nashville, Tennessee 37240, USA
    Biol Psychiatry 74:99-105. 2013
  6. pmc Dopaminergic mechanisms of individual differences in human effort-based decision-making
    Michael T Treadway
    Department of Psychology, Vanderbilt University, Nashville, Tennessee 37240, USA
    J Neurosci 32:6170-6. 2012
  7. pmc A unique role for the human amygdala in novelty detection
    Jennifer Urbano Blackford
    Department of Psychiatry, Vanderbilt University Medical School, Nashville, TN 37212, USA
    Neuroimage 50:1188-93. 2010
  8. doi request reprint The neural correlates of third-party punishment
    Joshua W Buckholtz
    Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
    Neuron 60:930-40. 2008
  9. pmc Worth the 'EEfRT'? The effort expenditure for rewards task as an objective measure of motivation and anhedonia
    Michael T Treadway
    Department of Psychology, Vanderbilt University, Nashville, TN, USA
    PLoS ONE 4:e6598. 2009
  10. doi request reprint On the use and misuse of genomic and neuroimaging science in forensic psychiatry: current roles and future directions
    Michael T Treadway
    Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
    Child Adolesc Psychiatr Clin N Am 20:533-46. 2011

Detail Information

Publications12

  1. doi request reprint Psychopathology and the human connectome: toward a transdiagnostic model of risk for mental illness
    Joshua W Buckholtz
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Neuron 74:990-1004. 2012
    ..We argue that risk-associated disruption of these circuits mediates susceptibility to broad domains of psychopathology rather than discrete disorders...
  2. pmc Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits
    Joshua W Buckholtz
    Department of Psychology, Vanderbilt University, Nashville, Tennessee, USA
    Nat Neurosci 13:419-21. 2010
    ..These findings suggest that neurochemical and neurophysiological hyper-reactivity of the dopaminergic reward system may comprise a neural substrate for impulsive-antisocial behavior and substance abuse in psychopathy...
  3. pmc Dopaminergic network differences in human impulsivity
    Joshua W Buckholtz
    Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
    Science 329:532. 2010
    ..Path analysis confirmed that the impact of decreased midbrain D2/D3 autoreceptor availability on trait impulsivity is mediated in part through its effect on stimulated striatal DA release...
  4. doi request reprint MAOA and the neurogenetic architecture of human aggression
    Joshua W Buckholtz
    Vanderbilt Brain Institute and Department of Psychology, Vanderbilt University, Nashville, TN 37212, USA
    Trends Neurosci 31:120-9. 2008
    ..Our construct provides a neurobiologically consistent model for gene-environment interactions in impulsive aggression...
  5. pmc A thalamocorticostriatal dopamine network for psychostimulant-enhanced human cognitive flexibility
    Gregory R Samanez-Larkin
    Department of Psychology, Vanderbilt University, Nashville, Tennessee Institute of Imaging Science, Vanderbilt University, Nashville, Tennessee 37240, USA
    Biol Psychiatry 74:99-105. 2013
    ..Everyday life demands continuous flexibility in thought and behavior. We examined whether individual differences in dopamine function are related to variability in the effects of amphetamine on one aspect of flexibility: task switching...
  6. pmc Dopaminergic mechanisms of individual differences in human effort-based decision-making
    Michael T Treadway
    Department of Psychology, Vanderbilt University, Nashville, Tennessee 37240, USA
    J Neurosci 32:6170-6. 2012
    ..These findings highlight the role of DA signaling in striatal, prefrontal, and insular regions as key neurochemical mechanisms underlying individual differences in cost/benefit decision-making...
  7. pmc A unique role for the human amygdala in novelty detection
    Jennifer Urbano Blackford
    Department of Psychiatry, Vanderbilt University Medical School, Nashville, TN 37212, USA
    Neuroimage 50:1188-93. 2010
    ..These findings suggest that the amygdala is distinctly responsive to novel unusual stimuli, making a unique contribution to the novelty detection circuit...
  8. doi request reprint The neural correlates of third-party punishment
    Joshua W Buckholtz
    Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
    Neuron 60:930-40. 2008
    ....
  9. pmc Worth the 'EEfRT'? The effort expenditure for rewards task as an objective measure of motivation and anhedonia
    Michael T Treadway
    Department of Psychology, Vanderbilt University, Nashville, TN, USA
    PLoS ONE 4:e6598. 2009
    ..Using the EEfRT, we test the hypothesis that effort-based decision-making is related to trait anhedonia...
  10. doi request reprint On the use and misuse of genomic and neuroimaging science in forensic psychiatry: current roles and future directions
    Michael T Treadway
    Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
    Child Adolesc Psychiatr Clin N Am 20:533-46. 2011
    ....
  11. ncbi request reprint Dysfunctional prefrontal regional specialization and compensation in schizophrenia
    Hao Yang Tan
    Unit on Functional MRI, Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, 10 Center Dr, Rm 4C 216, MSC 1364, Bethesda, MD 20892 1364, USA
    Am J Psychiatry 163:1969-77. 2006
    ....
  12. pmc Neural mechanisms of genetic risk for impulsivity and violence in humans
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, Neuroimaging Core Facility, National Institutes of Health, Department of Health and Human Services, 9000 Rockville Pike, Bethesda, MD 20892 1365, USA
    Proc Natl Acad Sci U S A 103:6269-74. 2006
    ....