Research Topics
Species | Joshua W BuckholtzSummaryAffiliation: Vanderbilt University Country: USA Publications
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Publications
MAOA and the neurogenetic architecture of human aggressionJoshua W Buckholtz
Vanderbilt Brain Institute and Department of Psychology, Vanderbilt University, Nashville, TN 37212, USA
Trends Neurosci 31:120-9. 2008..Our construct provides a neurobiologically consistent model for gene-environment interactions in impulsive aggression...
Dopaminergic network differences in human impulsivityJoshua W Buckholtz
Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
Science 329:532. 2010..Path analysis confirmed that the impact of decreased midbrain D2/D3 autoreceptor availability on trait impulsivity is mediated in part through its effect on stimulated striatal DA release...
Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traitsJoshua W Buckholtz
Department of Psychology, Vanderbilt University, Nashville, Tennessee, USA
Nat Neurosci 13:419-21. 2010..These findings suggest that neurochemical and neurophysiological hyper-reactivity of the dopaminergic reward system may comprise a neural substrate for impulsive-antisocial behavior and substance abuse in psychopathy...
Dopaminergic mechanisms of individual differences in human effort-based decision-makingMichael T Treadway
Department of Psychology, Vanderbilt University, Nashville, Tennessee 37240, USA
J Neurosci 32:6170-6. 2012..These findings highlight the role of DA signaling in striatal, prefrontal, and insular regions as key neurochemical mechanisms underlying individual differences in cost/benefit decision-making...
A unique role for the human amygdala in novelty detectionJennifer Urbano Blackford
Department of Psychiatry, Vanderbilt University Medical School, Nashville, TN 37212, USA
Neuroimage 50:1188-93. 2010..These findings suggest that the amygdala is distinctly responsive to novel unusual stimuli, making a unique contribution to the novelty detection circuit...
Psychopathology and the human connectome: toward a transdiagnostic model of risk for mental illnessJoshua W Buckholtz
Department of Psychology, Harvard University, Cambridge, MA 02138, USA
Neuron 74:990-1004. 2012..We argue that risk-associated disruption of these circuits mediates susceptibility to broad domains of psychopathology rather than discrete disorders...
The neural correlates of third-party punishmentJoshua W Buckholtz
Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
Neuron 60:930-40. 2008....
Worth the 'EEfRT'? The effort expenditure for rewards task as an objective measure of motivation and anhedoniaMichael T Treadway
Department of Psychology, Vanderbilt University, Nashville, TN, USA
PLoS ONE 4:e6598. 2009..Using the EEfRT, we test the hypothesis that effort-based decision-making is related to trait anhedonia...
On the use and misuse of genomic and neuroimaging science in forensic psychiatry: current roles and future directionsMichael T Treadway
Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
Child Adolesc Psychiatr Clin N Am 20:533-46. 2011....
Dysfunctional prefrontal regional specialization and compensation in schizophreniaHao Yang Tan
Unit on Functional MRI, Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, 10 Center Dr, Rm 4C 216, MSC 1364, Bethesda, MD 20892 1364, USA
Am J Psychiatry 163:1969-77. 2006....
Neural mechanisms of genetic risk for impulsivity and violence in humansAndreas Meyer-Lindenberg
Unit for Systems Neuroscience in Psychiatry, Neuroimaging Core Facility, National Institutes of Health, Department of Health and Human Services, 9000 Rockville Pike, Bethesda, MD 20892 1365, USA
Proc Natl Acad Sci U S A 103:6269-74. 2006....
