Research Topics
| William Victor BoboSummaryAffiliation: Vanderbilt University Country: USA Publications
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Detail Information
Publications
Asenapine, iloperidone and lurasidone: critical appraisal of the most recently approved pharmacotherapies for schizophrenia in adultsWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA
Expert Rev Clin Pharmacol 6:61-91. 2013..As such, the exact place of iloperidone, asenapine and lurasidone within the broader antipsychotic armamentarium is currently difficult to establish...
Trends in the use of antiepileptic drugs among pregnant women in the US, 2001-2007: a medication exposure in pregnancy risk evaluation program studyWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine Nashville, TN 37211, USA
Paediatr Perinat Epidemiol 26:578-88. 2012..Little is known about the extent of antiepileptic drug (AED) use in pregnancy, particularly for newer agents. Our objective was to assess whether AED use has increased among pregnant women in the US, 2001-2007...- Positive predictive value of a case definition for diabetes mellitus using automated administrative health data in children and youth exposed to antipsychotic drugs or control medications: a Tennessee Medicaid studyWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
BMC Med Res Methodol 12:128. 2012..We developed and validated an automated database case definition for diabetes in children and youth to facilitate pharmacoepidemiologic investigations of medications and the risk of diabetes... - Changes in weight and body mass index during treatment with melperone, clozapine and typical neurolepticsWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA
Psychiatry Res 176:114-9. 2010..Because of the relationship between BMI and cardiovascular risk, melperone deserves further study as both a first line treatment and as an alternative to clozapine in refractory schizophrenia... - Efficacy, safety and tolerability of Symbyax for acute-phase management of treatment-resistant depressionWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, South Suite 2200, Village at Vanderbilt, Nashville, TN 37212, USA
Expert Rev Neurother 10:651-70. 2010..As such, the exact place of OFC among the available therapeutic options for TRD is not fully understood at this time... - Risperidone long-acting injectable (Risperdal Consta®) for maintenance treatment in patients with bipolar disorderWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, 1500 21st Ave, South, Suite 2200, Village at Vanderbilt, Nashville, TN 37212, USA
Expert Rev Neurother 10:1637-58. 2010..Responder-enriched designs and exclusion of important clinical subgroups in the double-blind trials may limit translation of these results to routine care settings... - Randomized comparison of selective serotonin reuptake inhibitor (escitalopram) monotherapy and antidepressant combination pharmacotherapy for major depressive disorder with melancholic features: a CO-MED reportWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA
J Affect Disord 133:467-76. 2011..The clinical effects of antidepressant combinations vs. monotherapy as initial treatment for major depression with melancholic features (MDD-MF) are unknown... - The effect of adjunctive armodafinil on cognitive performance and psychopathology in antipsychotic-treated patients with schizophrenia/schizoaffective disorder: a randomized, double-blind, placebo-controlled trialWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA
Schizophr Res 130:106-13. 2011..The efficacy, safety and tolerability of adjunctive armodafinil for cognitive performance, and negative and affective symptoms, were examined in 60 patients with schizophrenia or schizoaffective disorder... - Prediction of long-term metabolic effects of olanzapine and risperidone treatment from baseline body mass index in schizophrenia and bipolar disorderWilliam Victor Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA
Psychiatry Res 189:200-7. 2011..Individuals with normal baseline BMI may be most susceptible to OLZ-induced hyperlipidosis. Frequency of metabolic screening should be independent of baseline BMI or rapid increases in BMI... 
Effects of orally disintegrating vs regular olanzapine tablets on body weight, eating behavior, glycemic and lipid indices, and gastrointestinal hormones: a randomized, open comparison in outpatients with bipolar depressionWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
Ann Clin Psychiatry 23:193-201. 2011..This randomized, open-label trial aimed to compare the metabolic effects of olanzapine orally disintegrating tablets (ODT) and solid oral tablets (SOT) in bipolar depressed and mixed outpatients...- Converting from brand-name to generic clozapine: a review of effectiveness and tolerability dataWilliam V Bobo
Department of Psychiatry, School of Medicine, Vanderbilt University, 1601 23rd Avenue South, Suite 3035, Nashville, TN 37212, USA
Am J Health Syst Pharm 67:27-37. 2010..The effectiveness and tolerability of switching patients' therapy from brand-name to generic clozapine are reviewed... - Olanzapine monotherapy for acute depression in patients with bipolar I or II disorder: results of an 8-week open label trialWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine Nashville, Tennessee 37212, USA
Hum Psychopharmacol 25:30-6. 2010..Olanzapine may be an effective, well-tolerated option for treating acute non-psychotic depression across a variety of bipolar disorder subtypes... - Fluoxetine and olanzapine combination therapy in treatment-resistant major depression: review of efficacy and safety dataWilliam Victor Bobo
Vanderbilt University School of Medicine, Department of Psychiatry, 1500 21st Ave South, Village at Vanderbilt, Nashville, TN 37212, USA
Expert Opin Pharmacother 10:2145-59. 2009..There has been growing evidence supporting the use of atypical antipsychotic drugs as adjunctive treatments in patients with major depression who fail to respond adequately to antidepressants... - Recurring episodes of Bell's mania after cerebrovascular accidentWilliam V Bobo
Dept of Psychiatry, Vanderbilt Univ School of Medicine, Vanderbilt Psychiatric Hospital, Suite 3035, 1601 23 Ave South, Nashville, TN 37212, USA
Psychosomatics 50:285-8. 2009..Catatonia is a common feature of the syndrome... - Melperone, an aytpical antipsychotic drug with clozapine-like effect on plasma prolactin: contrast with typical neurolepticsWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee 37211, USA
Hum Psychopharmacol 24:415-22. 2009..To evaluate the effect of melperone, a butyrophenone with atypical antipsychotic properties, on plasma prolactin (PRL) concentrations compared with clozapine and typical neuroleptics... - The effect of psychiatric third-year rotation setting on academic performance, student attitudes, and specialty choiceWilliam V Bobo
Vanderbilt University School of Medicine, Department of Psychiatry, Nashville, TN 37212, USA
Acad Psychiatry 33:105-11. 2009..The goal of this study was to assess the extent to which rotation type influenced these outcome variables among third-year medical students... - A randomized open comparison of long-acting injectable risperidone and treatment as usual for prevention of relapse, rehospitalization, and urgent care referral in community-treated patients with rapid cycling bipolar disorderWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA
Clin Neuropharmacol 34:224-33. 2011..To compare adjunctive long-acting injectable risperidone plus treatment as usual (RLAI+TAU) versus TAU alone for relapse, rehospitalization, and urgent care events in patients with bipolar disorder in routine care settings... - Interpreting the efficacy findings in the CATIE study: what clinicians should knowHerbert Y Meltzer
Psychopharmacology Division, Vanderbilt University Medical Center, Nashville, TX 37215, USA
CNS Spectr 11:14-24. 2006..In particular, the use of a higher-than-usual peak dose of olanzapine may have led to the superior results achieved with it. Practical suggestions are given for choice of antipsychotic medication in patients with chronic schizophrenia... - A randomized, double-blind comparison of clozapine and high-dose olanzapine in treatment-resistant patients with schizophreniaHerbert Y Meltzer
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tenn, USA
J Clin Psychiatry 69:274-85. 2008..There are conflicting data concerning the potential utility of olanzapine in treatment-resistant schizophrenia at doses beyond the 10- to 20-mg/day range that has proven to be effective for most nonrefractory patients with schizophrenia... - Efficacy and tolerability of oral paliperidone extended-release tablets in the treatment of acute schizophrenia: pooled data from three 6-week, placebo-controlled studiesHerbert Y Meltzer
Department of Psychiatry, Vanderbilt Medical Center, Nashville, TN, USA
J Clin Psychiatry 69:817-29. 2008..To evaluate the efficacy and safety of an extended-release (ER) formulation of paliperidone in patients with an acute episode of schizophrenia, in the dosage range of 3 to 15 mg daily... - A randomized trial comparing clozapine and typical neuroleptic drugs in non-treatment-resistant schizophreniaHerbert Y Meltzer
Department of Psychiatry, School of Medicine, Vanderbilt University, Nashville, TN, USA
Psychiatry Res 177:286-93. 2010..These considerations should be taken into account in decisions of how best to utilize clozapine in the treatment of schizophrenia... - Characteristics of repeat users of an inpatient psychiatry service at a large military tertiary care hospitalWilliam V Bobo
Department of Psychiatry, Walter Reed Army Medical Center, Washington, DC, 20307, USA
Mil Med 169:648-53. 2004.... - The management of post traumatic stress disorder (PTSD) in the primary care settingWilliam V Bobo
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA
South Med J 100:797-802. 2007..Early detection by primary care providers and rapid initiation of treatment are the keys to successful management of the disorder... - Early career professional development issues for military academic psychiatristsChristopher H Warner
Department of Psychiatry, Walter Reed Army Medical Center, Washington, DC, USA
Acad Psychiatry 29:437-42. 2005..Academically motivated graduates of military psychiatric residency programs confront serious challenges...