- Cytokine receptor-like factor 1 (CRLF1) protects against 6-hydroxydopamine toxicity independent of the gp130/JAK signaling pathwayBrendan D Looyenga
Laboratory of Systems Biology, Van Andel Research Institute, Grand Rapids, Michigan, USA
PLoS ONE 8:e66548. 2013..These data provide an additional role for CRLF1 that could potentially explain its broad expression pattern and effects on cells lacking expression of this receptor. ..
- STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinomaBrendan D Looyenga
Systems Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America
PLoS ONE 7:e30820. 2012....
- Combined gene expression profiling and RNAi screening in clear cell renal cell carcinoma identify PLK1 and other therapeutic kinase targetsYan Ding
Van Andel Research Institute, Grand Rapids, MI, USA
Cancer Res 71:5225-34. 2011..Taken together, these findings highlight PLK1 as a rational therapeutic target for ccRCC...
- Tailoring tyrosine kinase inhibitors to fit the lung cancer genomeBrendan D Looyenga
Van Andel Research Institute, Systems Biology, Grand Rapids, MI, USA
Transl Oncol 4:59-70. 2011....