Linda K Teuschler

Summary

Affiliation: U.S. Environmental Protection Agency
Country: USA

Publications

  1. ncbi request reprint The interaction effects of binary mixtures of benzene and toluene on the developing heart of medaka (Oryzias latipes)
    Linda K Teuschler
    US Environmental Protection Agency, National Center for Environmental Assessment, Mail Stop 190, 26 W Martin Luther King Dr, Cincinnati, OH 45268, USA
    Chemosphere 58:1283-91. 2005
  2. ncbi request reprint Deciding which chemical mixtures risk assessment methods work best for what mixtures
    Linda K Teuschler
    U S Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Cincinnati, OH 45268, USA
    Toxicol Appl Pharmacol 223:139-47. 2007
  3. pmc Evaluating quantitative formulas for dose-response assessment of chemical mixtures
    Richard C Hertzberg
    Office of Research and Development, National Center for Environmental Assessment, U S Environmental Protection Agency, Cincinnati, Ohio, USA
    Environ Health Perspect 110:965-70. 2002
  4. ncbi request reprint Component-based and whole-mixture techniques for addressing the toxicity of drinking-water disinfection by-product mixtures
    Jane Ellen Simmons
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health A 67:741-54. 2004
  5. ncbi request reprint A feasibility study of cumulative risk assessment methods for drinking water disinfection by-product mixtures
    Linda K Teuschler
    U S EPA National Center for Environmental Assessment, 26 West Martin Luther King Drive MS 190, Cincinnati, OH 45268, USA
    J Toxicol Environ Health A 67:755-77. 2004
  6. doi request reprint Integrated disinfection by-products research: assessing reproductive and developmental risks posed by complex disinfection by-product mixtures
    Glenn Rice
    U S Environmental Protection Agency, Cincinnati, Ohio 45268, USA
    J Toxicol Environ Health A 71:1222-34. 2008
  7. doi request reprint Concentration, chlorination, and chemical analysis of drinking water for disinfection byproduct mixtures health effects research: U.S. EPA's Four Lab Study
    Jonathan G Pressman
    National Risk Management Research Laboratory, US EPA, Cincinnati, Ohio 45268, USA
    Environ Sci Technol 44:7184-92. 2010
  8. doi request reprint Developmental toxicity evaluations of whole mixtures of disinfection by-products using concentrated drinking water in rats: gestational and lactational effects of sulfate and sodium
    Michael G Narotsky
    NHEERL MD 67, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Birth Defects Res B Dev Reprod Toxicol 95:202-12. 2012
  9. doi request reprint Disinfection byproduct formation in reverse-osmosis concentrated and lyophilized natural organic matter from a drinking water source
    Jonathan G Pressman
    National Risk Management Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Cincinnati, OH 45268, USA
    Water Res 46:5343-54. 2012
  10. doi request reprint Evaluating the similarity of complex drinking-water disinfection by-product mixtures: overview of the issues
    Glenn E Rice
    U S Environmental Protection Agency, Cincinnati, Ohio 45268, USA
    J Toxicol Environ Health A 72:429-36. 2009

Detail Information

Publications15

  1. ncbi request reprint The interaction effects of binary mixtures of benzene and toluene on the developing heart of medaka (Oryzias latipes)
    Linda K Teuschler
    US Environmental Protection Agency, National Center for Environmental Assessment, Mail Stop 190, 26 W Martin Luther King Dr, Cincinnati, OH 45268, USA
    Chemosphere 58:1283-91. 2005
    ..This work uses an established statistical method to evaluate the toxicity of an environmentally relevant mixture to ascertain whether interaction effects are occurring, thus providing additional information on toxicity...
  2. ncbi request reprint Deciding which chemical mixtures risk assessment methods work best for what mixtures
    Linda K Teuschler
    U S Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Cincinnati, OH 45268, USA
    Toxicol Appl Pharmacol 223:139-47. 2007
    ....
  3. pmc Evaluating quantitative formulas for dose-response assessment of chemical mixtures
    Richard C Hertzberg
    Office of Research and Development, National Center for Environmental Assessment, U S Environmental Protection Agency, Cincinnati, Ohio, USA
    Environ Health Perspect 110:965-70. 2002
    ..g., as the toxicologic interactions disappear). These ideas are illustrated using dose addition and two weight-of-evidence formulas for incorporating toxicologic interactions...
  4. ncbi request reprint Component-based and whole-mixture techniques for addressing the toxicity of drinking-water disinfection by-product mixtures
    Jane Ellen Simmons
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health A 67:741-54. 2004
    ....
  5. ncbi request reprint A feasibility study of cumulative risk assessment methods for drinking water disinfection by-product mixtures
    Linda K Teuschler
    U S EPA National Center for Environmental Assessment, 26 West Martin Luther King Drive MS 190, Cincinnati, OH 45268, USA
    J Toxicol Environ Health A 67:755-77. 2004
    ..Research needs to improve this approach are presented...
  6. doi request reprint Integrated disinfection by-products research: assessing reproductive and developmental risks posed by complex disinfection by-product mixtures
    Glenn Rice
    U S Environmental Protection Agency, Cincinnati, Ohio 45268, USA
    J Toxicol Environ Health A 71:1222-34. 2008
    ....
  7. doi request reprint Concentration, chlorination, and chemical analysis of drinking water for disinfection byproduct mixtures health effects research: U.S. EPA's Four Lab Study
    Jonathan G Pressman
    National Risk Management Research Laboratory, US EPA, Cincinnati, Ohio 45268, USA
    Environ Sci Technol 44:7184-92. 2010
    ....
  8. doi request reprint Developmental toxicity evaluations of whole mixtures of disinfection by-products using concentrated drinking water in rats: gestational and lactational effects of sulfate and sodium
    Michael G Narotsky
    NHEERL MD 67, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Birth Defects Res B Dev Reprod Toxicol 95:202-12. 2012
    ..There were no treatment-related clinical findings, indicating that mixtures produced by the second method are suitable for multigenerational testing...
  9. doi request reprint Disinfection byproduct formation in reverse-osmosis concentrated and lyophilized natural organic matter from a drinking water source
    Jonathan G Pressman
    National Risk Management Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Cincinnati, OH 45268, USA
    Water Res 46:5343-54. 2012
    ..This study suggests that lyophilization can be used to preserve concentrated NOM without substantially altering the precursors to DBP formation...
  10. doi request reprint Evaluating the similarity of complex drinking-water disinfection by-product mixtures: overview of the issues
    Glenn E Rice
    U S Environmental Protection Agency, Cincinnati, Ohio 45268, USA
    J Toxicol Environ Health A 72:429-36. 2009
    ..g., mutagenicity); and summary chemical measures such as total trihalomethanes, total haloacetic acids, total haloacetonitriles, and the levels of bromide incorporation in the DBP classes...
  11. pmc Development of a research strategy for integrated technology-based toxicological and chemical evaluation of complex mixtures of drinking water disinfection byproducts
    Jane Ellen Simmons
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 110:1013-24. 2002
    ....
  12. doi request reprint Research issues underlying the four-lab study: integrated disinfection by-products mixtures research
    Jane Ellen Simmons
    National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC, USA
    J Toxicol Environ Health A 71:1125-32. 2008
    ..A phased research plan was developed and implemented. The present series of articles provides the results from the first series of experiments...
  13. ncbi request reprint The impact of cytochrome P450 2E1-dependent metabolic variance on a risk-relevant pharmacokinetic outcome in humans
    John C Lipscomb
    US EPA, ORD, NCEA, Cincinnati, OH 45268, USA
    Risk Anal 23:1221-38. 2003
    ..Integration of in vitro metabolism information into physiological models may reduce the uncertainties associated with risk contributions of differences in enzyme expression and the UF that represent PK variability...
  14. pmc An in silico approach for evaluating a fraction-based, risk assessment method for total petroleum hydrocarbon mixtures
    Nina Ching Y Wang
    National Center for Environmental Assessment, Office of Research and Development, U S Environmental Protection Agency, Cincinnati, OH 45268, USA
    J Toxicol 2012:410143. 2012
    ..Furthermore, the results support the general methodology of mixture risk assessment to assess both cancer and noncancer risk values after the application of fractionation...
  15. ncbi request reprint Risk assessment for benefits analysis: framework for analysis of a thyroid-disrupting chemical
    Daniel A Axelrad
    U S Environmental Protection Agency, Office of Policy, Economics and Innovation, Washington, DC, USA
    J Toxicol Environ Health A 68:837-55. 2005
    ..Detailed implementation of the case study framework will be presented in future publications...