U P Kodavanti

Summary

Affiliation: U.S. Environmental Protection Agency
Country: USA

Publications

  1. pmc Consistent pulmonary and systemic responses from inhalation of fine concentrated ambient particles: roles of rat strains used and physicochemical properties
    Urmila P Kodavanti
    Pulmonary Toxicology Branch, Experimental Toxicology Division, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Health Perspect 113:1561-8. 2005
  2. pmc The role of particulate matter-associated zinc in cardiac injury in rats
    Urmila P Kodavanti
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27710, USA
    Environ Health Perspect 116:13-20. 2008
  3. ncbi request reprint Cardiopulmonary responses of intratracheally instilled tire particles and constituent metal components
    Reddy R Gottipolu
    National Research Council, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Inhal Toxicol 20:473-84. 2008
  4. pmc One-month diesel exhaust inhalation produces hypertensive gene expression pattern in healthy rats
    Reddy R Gottipolu
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 117:38-46. 2009
  5. pmc Subchronic pulmonary pathology, iron overload, and transcriptional activity after Libby amphibole exposure in rat models of cardiovascular disease
    Jonathan H Shannahan
    Curriculum in Toxicology, University of North Carolina School of Medicine, Chapel Hill, NC 27711, USA
    Environ Health Perspect 120:85-91. 2012
  6. doi request reprint Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention
    Urmila P Kodavanti
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory NHEERL, Office of Research and Development ORD, U S Environmental Protection Agency EPA, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 268:232-40. 2013
  7. ncbi request reprint Rodent models of susceptibility: what is their place in inhalation toxicology?
    U P Kodavanti
    Pulmonary Toxicology Branch, MD 82, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Respir Physiol 128:57-70. 2001
  8. ncbi request reprint Temporal association between pulmonary and systemic effects of particulate matter in healthy and cardiovascular compromised rats
    Urmila P Kodavanti
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health A 65:1545-69. 2002
  9. ncbi request reprint Inhaled environmental combustion particles cause myocardial injury in the Wistar Kyoto rat
    Urmila P Kodavanti
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 71:237-45. 2003
  10. pmc Vascular and cardiac impairments in rats inhaling ozone and diesel exhaust particles
    Urmila P Kodavanti
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 119:312-8. 2011

Collaborators

Detail Information

Publications46

  1. pmc Consistent pulmonary and systemic responses from inhalation of fine concentrated ambient particles: roles of rat strains used and physicochemical properties
    Urmila P Kodavanti
    Pulmonary Toxicology Branch, Experimental Toxicology Division, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Health Perspect 113:1561-8. 2005
    ..Biologic effects were evident in those six studies. These studies demonstrate a pattern of rat strain-specific pulmonary and systemic effects that are not linked to high mass but appear to be dependent on CAP chemical composition...
  2. pmc The role of particulate matter-associated zinc in cardiac injury in rats
    Urmila P Kodavanti
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27710, USA
    Environ Health Perspect 116:13-20. 2008
    ..Exposure to particulate matter (PM) has been associated with increased cardiovascular morbidity; however, causative components are unknown. Zinc is a major element detected at high levels in urban air...
  3. ncbi request reprint Cardiopulmonary responses of intratracheally instilled tire particles and constituent metal components
    Reddy R Gottipolu
    National Research Council, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Inhal Toxicol 20:473-84. 2008
    ..The observed acute pulmonary toxicity of TP could be due to the presence of water soluble Zn and Cu. At high concentrations these metals may induce cardiac oxidative stress...
  4. pmc One-month diesel exhaust inhalation produces hypertensive gene expression pattern in healthy rats
    Reddy R Gottipolu
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 117:38-46. 2009
    ..Exposure to diesel exhaust (DE) is linked to vasoconstriction, endothelial dysfunction, and myocardial ischemia in compromised individuals...
  5. pmc Subchronic pulmonary pathology, iron overload, and transcriptional activity after Libby amphibole exposure in rat models of cardiovascular disease
    Jonathan H Shannahan
    Curriculum in Toxicology, University of North Carolina School of Medicine, Chapel Hill, NC 27711, USA
    Environ Health Perspect 120:85-91. 2012
    ..Surface-available iron (Fe) is proposed to contribute to asbestos-induced toxicity through the production of reactive oxygen species...
  6. doi request reprint Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention
    Urmila P Kodavanti
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory NHEERL, Office of Research and Development ORD, U S Environmental Protection Agency EPA, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 268:232-40. 2013
    ..ET-1 was decreased by HYD. In conclusion, antihypertensive drug treatment reduces gas and DE-induced pulmonary protein leakage and expression of vascular atherogenic markers...
  7. ncbi request reprint Rodent models of susceptibility: what is their place in inhalation toxicology?
    U P Kodavanti
    Pulmonary Toxicology Branch, MD 82, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Respir Physiol 128:57-70. 2001
    ..As existing models gain wider use, our understanding of the models will improve and encourage refinements/development of models that integrate both genetic and environmental factors to better mimic the human condition...
  8. ncbi request reprint Temporal association between pulmonary and systemic effects of particulate matter in healthy and cardiovascular compromised rats
    Urmila P Kodavanti
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health A 65:1545-69. 2002
    ..This evidence is consistent with greater cardiovascular events during acute PM episodes in compromised humans...
  9. ncbi request reprint Inhaled environmental combustion particles cause myocardial injury in the Wistar Kyoto rat
    Urmila P Kodavanti
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 71:237-45. 2003
    ..These findings provide supportive evidence for the epidemiological associations of cardiovascular morbidity and ambient PM...
  10. pmc Vascular and cardiac impairments in rats inhaling ozone and diesel exhaust particles
    Urmila P Kodavanti
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 119:312-8. 2011
    ..Mechanisms of cardiovascular injuries from exposure to gas and particulate air pollutants are unknown...
  11. ncbi request reprint The spontaneously hypertensive rat: an experimental model of sulfur dioxide-induced airways disease
    Urmila P Kodavanti
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina, 27711, USA
    Toxicol Sci 94:193-205. 2006
    ..SO(2) effects on these genes were more pronounced in SH than in SD rats. Thus, SO(2) exposure in SH rats may yield a relevant experimental model of bronchitis...
  12. ncbi request reprint Pulmonary and systemic effects of zinc-containing emission particles in three rat strains: multiple exposure scenarios
    Urmila P Kodavanti
    Pulmonary Toxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Toxicol Sci 70:73-85. 2002
    ..Inhalation exposures may result in particle accumulation and macrophage recruitment with potential strain differences in EPM clearance...
  13. ncbi request reprint Acute lung injury from intratracheal exposure to fugitive residual oil fly ash and its constituent metals in normo- and spontaneously hypertensive rats
    U P Kodavanti
    Pulmonary Toxicology Branch, MD 82, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Inhal Toxicol 13:37-54. 2001
    ..The metallic constituents of ROFA produced these effects in a strain-specific manner such that, at the dose level used, V caused pulmonary injury only in WKY rats, whereas Ni was toxic to both strains...
  14. ncbi request reprint Variable pulmonary responses from exposure to concentrated ambient air particles in a rat model of bronchitis
    U P Kodavanti
    Pulmonary Toxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Toxicol Sci 54:441-51. 2000
    ..Additionally, potential variability in pathology of induced bronchitis or other lung disease may decrease the ability to distinguish toxic injury due to PM...
  15. ncbi request reprint Effects of instilled combustion-derived particles in spontaneously hypertensive rats. Part II: Pulmonary responses
    L B Wichers
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina, Chapel Hill, USA
    Inhal Toxicol 16:407-19. 2004
    ..This study demonstrates significant deficits in pulmonary function, along with significant increases in BALF indices of pulmonary inflammation and injury in SH rats after IT exposure to HP-12...
  16. ncbi request reprint Lung injury from intratracheal and inhalation exposures to residual oil fly ash in a rat model of monocrotaline-induced pulmonary hypertension
    U P Kodavanti
    Pulmonary Toxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health A 57:543-63. 1999
    ..In summary, only the bolus IT ROFA caused mortality in the rat model of lung injury/hypertension. Exacerbation of histological lesions and cytokine mRNA expression were most reflective of increased ROFA susceptibility in this model...
  17. doi request reprint Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole
    J H Shannahan
    Curriculum in Toxicology, UNC School of Medicine, Chapel Hill, North Carolina, USA
    J Toxicol Environ Health A 75:213-31. 2012
    ..These changes were similar to those noted at baseline in SH and SHHF rats, suggesting that LA-induced pulmonary injury might increase the risk of developing cardiovascular disease in healthy individuals...
  18. ncbi request reprint Cardiopulmonary responses of Wistar Kyoto, spontaneously hypertensive, and stroke-prone spontaneously hypertensive rats to particulate matter (PM) exposure
    J Grace Wallenborn
    Department of Environmental Sciences and Engineering, University of North Carolina School of Public Health, Chapel Hill, North Carolina, USA
    J Toxicol Environ Health A 70:1912-22. 2007
    ..Preexisting cardiovascular disease may influence susceptibility to PM pulmonary and cardiac health effects in a disease-specific manner...
  19. ncbi request reprint Cardiovascular and thermoregulatory effects of inhaled PM-associated transition metals: a potential interaction between nickel and vanadium sulfate
    M J Campen
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina, Chapel Hill, NC 27599, USA
    Toxicol Sci 64:243-52. 2001
    ..1 mg/m(3)) alone. These results indicate a possible synergistic relationship between inhaled Ni and V, and provide insight into potential interactions regarding the toxicity of PM-associated metals...
  20. ncbi request reprint Ozone induces glucose intolerance and systemic metabolic effects in young and aged Brown Norway rats
    V Bass
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC, USA
    Toxicol Appl Pharmacol 273:551-60. 2013
    ..In conclusion, acute ozone exposure induces marked systemic metabolic impairments in BN rats of all ages, likely through sympathetic stimulation...
  21. ncbi request reprint Susceptibility of adult and senescent Brown Norway rats to repeated ozone exposure: an assessment of behavior, serum biochemistry and cardiopulmonary function
    C J Gordon
    Toxicity Assessment Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Inhal Toxicol 25:141-59. 2013
    ..Overall, adult rats exhibited more immediate effects of episodic O₃ than senescent rats. Residual effects were, however, obtained in both ages of rat, especially for ventilatory endpoints...
  22. ncbi request reprint Systemic imbalance of essential metals and cardiac gene expression in rats following acute pulmonary zinc exposure
    Peter S Gilmour
    Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA
    J Toxicol Environ Health A 69:2011-32. 2006
    ..Imbalance of systemic metal homeostasis as a result of pulmonary zinc exposure may underlie the cause of extrapulmonary effects...
  23. doi request reprint Long-term response of rats to single intratracheal exposure of Libby amphibole or amosite
    J M Cyphert
    Curriculum in Toxicology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
    J Toxicol Environ Health A 75:183-200. 2012
    ..Data showed that LA was on a mass basis less potent than amosite...
  24. ncbi request reprint A pulmonary rat gene array for screening altered expression profiles in air pollutant-induced lung injury
    S S Nadadur
    Pulmonary Toxicology Branch, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, MD 82, Research Triangle Park, NC 27711, USA
    Inhal Toxicol 12:1239-54. 2000
    ..Developing a pulmonary rat gene array may provide a tool for screening the expression profile of tissue specific markers following exposure to toxic air contaminants...
  25. pmc Rodent models of cardiopulmonary disease: their potential applicability in studies of air pollutant susceptibility
    U P Kodavanti
    National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Environ Health Perspect 106:111-30. 1998
    ....
  26. ncbi request reprint Episodic ozone exposure in adult and senescent Brown Norway rats: acute and delayed effect on heart rate, core temperature and motor activity
    C J Gordon
    Toxicity Assessment Division, U S Environmental Protection Agency, Research Triangle Park, NC, USA
    Inhal Toxicol 26:380-90. 2014
    ..An attenuated inflammatory response to O(3) in senescent rats may explain the relatively heightened physiological response to O(3) in younger rats...
  27. doi request reprint Transcriptional activation of inflammasome components by Libby amphibole and the role of iron
    J H Shannahan
    Curriculum in Toxicology, UNC School of Medicine, Chapel Hill, NC, USA
    Inhal Toxicol 24:60-9. 2012
    ..The inflammasome activation by LA may contribute to fibrosis, and Fe may reduce this response and alter compensatory mechanisms in individuals exposed to LA...
  28. ncbi request reprint Effects of instilled combustion-derived particles in spontaneously hypertensive rats. Part I: Cardiovascular responses
    L B Wichers
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina, Chapel Hill, USA
    Inhal Toxicol 16:391-405. 2004
    ..This study demonstrates substantial dose-related deficits in cardiac function in SH rats after IT exposure to a low-metal content, combustion-derived particle...
  29. ncbi request reprint Cardiac and thermoregulatory effects of instilled particulate matter-associated transition metals in healthy and cardiopulmonary-compromised rats
    Matthew J Campen
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USA
    J Toxicol Environ Health A 65:1615-31. 2002
    ..These data suggest that the biphasic response to instilled ROFA may result from a summation of the temporally different effects of V and Ni...
  30. ncbi request reprint Toxic responses of the lung to inhaled pollutants: benefits and limitations of lung-disease models
    Daniel L Costa
    Pulmonary Toxicology Branch, MD 82, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Lett 140:195-203. 2003
    ..No model should be used without careful consideration of its strengths and limitations. However, when interpreted in the context of field and epidemiology findings, they may reveal generic susceptibility attributes or useful biomarkers...
  31. doi request reprint Pulmonary oxidative stress, inflammation, and dysregulated iron homeostasis in rat models of cardiovascular disease
    Jonathan H Shannahan
    Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina, USA
    J Toxicol Environ Health A 73:641-56. 2010
    ....
  32. doi request reprint Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice
    Haiyan Tong
    Human Studies Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 239:224-32. 2009
    ..Further experiments are needed to understand the physico-chemical processes involved in this phenomenon...
  33. pmc Exposure to ultrafine carbon particles at levels below detectable pulmonary inflammation affects cardiovascular performance in spontaneously hypertensive rats
    Swapna Upadhyay
    EPA NHEERL, Research Triangle Park, NC 27709, USA
    Part Fibre Toxicol 5:19. 2008
    ..abstract:..
  34. doi request reprint Systemic translocation of (70)zinc: kinetics following intratracheal instillation in rats
    J Grace Wallenborn
    Department of Environmental Sciences and Engineering, UNC School of Public Health, Chapel Hill, NC 27599, USA
    Toxicol Appl Pharmacol 234:25-32. 2009
    ..Our data suggests that following pulmonary exposure, zinc accumulation and subsequent changes in normal metal homeostasis in the heart and other organs could induce cardiovascular injury...
  35. doi request reprint Subchronic inhalation of zinc sulfate induces cardiac changes in healthy rats
    J Grace Wallenborn
    Department of Environmental Sciences and Engineering, UNC School of Public Health, Chapel Hill, NC 27599, USA
    Toxicol Appl Pharmacol 232:69-77. 2008
    ..These data indicate that inhalation of zinc at environmentally relevant levels induces cardiac effects. While changes are small in healthy rats, these may be especially relevant in individuals with pre-existent cardiovascular disease...
  36. ncbi request reprint Altered gene expression profiles of rat lung in response to an emission particulate and its metal constituents
    Srikanth S Nadadur
    Pulmonary Toxicology Branch, ETD, NHEERL, ORD, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health A 65:1333-50. 2002
    ..Expression profiling using genomic approaches will aid in our understanding of toxicant-specific altered molecular pathways in lung injury and pathogenesis...
  37. ncbi request reprint Hypertensive rats are susceptible to TLR4-mediated signaling following exposure to combustion source particulate matter
    Peter S Gilmour
    Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, USA
    Inhal Toxicol 16:5-18. 2004
    ..Thus, one of the mechanisms for greater susceptibility of SH rats to PM exposure may involve an increased activation of the TLR4 signaling pathway...
  38. ncbi request reprint Pulmonary gene expression profiles of spontaneously hypertensive rats exposed to environmental tobacco smoke
    Srikanth S Nadadur
    Pulmonary Toxicology Branch, National Health and Environmental Effects Research Laboratory, Office of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Chest 121:83S-84S. 2002
  39. doi request reprint Aging and susceptibility to toluene in rats: a pharmacokinetic, biomarker, and physiological approach
    Christopher J Gordon
    National Health and Environmental Effects Research Laboratory, ORD, U S Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    J Toxicol Environ Health A 73:301-18. 2010
    ..The expression of several cardiac biochemical markers of toluene exposure in the aged may also reflect differential susceptibility to this toxicant...
  40. ncbi request reprint Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant
    Kevin R Smith
    Center for Health and the Environment, University of California, Davis, CA 95616, USA
    Free Radic Biol Med 33:1106-14. 2002
    ..05). We conclude that a synthetic catalytic antioxidant decreased the adverse effects of exposure to tobacco smoke...
  41. ncbi request reprint Systemic vascular disease in male B6C3F1 mice exposed to particulate matter by inhalation: studies conducted by the National Toxicology Program
    Carolyn F Moyer
    Pathology Associates, Raleigh, North Carolina 27606, USA
    Toxicol Pathol 30:427-34. 2002
    ..The results showed arteritis did not develop in the 90-day studies, suggesting that long-term chronic exposure to lower-dose metallic particulate matter may be necessary to induce or exacerbate arteritis...
  42. pmc Emission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension
    Sarah Y Gardner
    College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    Environ Health Perspect 112:872-8. 2004
    ..ROFA exposure induced histologic changes and abnormalities in several ventilatory parameters, many of which were enhanced by MCT treatment...
  43. ncbi request reprint Acute tobacco smoke-induced airways inflammation in spontaneously hypertensive rats
    Bei Yu
    Center for Health and the Environment, University of California, Davis, California 95616, USA
    Inhal Toxicol 20:623-33. 2008
    ..The spontaneously hypertensive rat may be a more relevant animal model of acute tobacco smoke-induced airway inflammation than other laboratory rats...
  44. ncbi request reprint Cardiovascular and blood coagulative effects of pulmonary zinc exposure
    Peter S Gilmour
    Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Toxicol Appl Pharmacol 211:41-52. 2006
    ..These data suggest that cardiovascular blood coagulation impairments are likely following pulmonary zinc exposure and associated pulmonary injury and inflammation...
  45. ncbi request reprint Systemic translocation of particulate matter-associated metals following a single intratracheal instillation in rats
    J Grace Wallenborn
    Department of Environmental Sciences and Engineering, UNC School of Public Health, Chapel Hill, North Carolina 27599, USA
    Toxicol Sci 98:231-9. 2007
    ....
  46. ncbi request reprint Acute pulmonary and systemic effects of inhaled coal fly ash in rats: comparison to ambient environmental particles
    Kevin R Smith
    Center for Health and the Environment, University of California, Davis, California 95616, USA
    Toxicol Sci 93:390-9. 2006
    ..This study furthers our understanding of possible mechanisms by which specific sources of particulate air pollution affect human health...