Peter P Egeghy

Summary

Affiliation: U.S. Environmental Protection Agency
Country: USA

Publications

  1. ncbi request reprint Determinants of temporal variability in NHEXAS-Maryland environmental concentrations, exposures, and biomarkers
    Peter P Egeghy
    US Environmental Protection Agency, National Exposure Research Laboratory, Human Exposure and Atmospheric Sciences Division, Research Triangle Park, NC 27711, USA
    J Expo Anal Environ Epidemiol 15:388-97. 2005
  2. doi request reprint The exposure data landscape for manufactured chemicals
    Peter P Egeghy
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, United States
    Sci Total Environ 414:159-66. 2012
  3. pmc Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population
    Bonnie R Joubert
    US Environmental Protection Agency EPA, National Exposure Research Laboratory, Durham, NC, USA
    BMC Med Genet 12:25. 2011
  4. pmc Review of pesticide urinary biomarker measurements from selected US EPA children's observational exposure studies
    Peter P Egeghy
    Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Int J Environ Res Public Health 8:1727-54. 2011
  5. doi request reprint Methodologies for estimating cumulative human exposures to current-use pyrethroid pesticides
    Nicolle S Tulve
    Office of Research and Development, National Exposure Research Laboratory, US EPA, MD E205 04, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 21:317-27. 2011
  6. ncbi request reprint Incorporating exposure information into the toxicological prioritization index decision support framework
    Sumit Gangwal
    National Center for Computational Toxicology NCCT, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC, USA
    Sci Total Environ 435:316-25. 2012
  7. ncbi request reprint Multimedia measurements and activity patterns in an observational pilot study of nine young children
    Nicolle S Tulve
    National Exposure Research Laboratory, US EPA, MD E205 04, Research Triangle Park, NC 27711, USA
    J Expo Sci Environ Epidemiol 18:31-44. 2008
  8. ncbi request reprint Adult and children's exposure to 2,4-D from multiple sources and pathways
    Marsha K Morgan
    National Exposure Research Laboratory, USEPA, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 18:486-94. 2008
  9. ncbi request reprint American Healthy Homes Survey: a national study of residential pesticides measured from floor wipes
    Daniel M Stout
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Sci Technol 43:4294-300. 2009
  10. doi request reprint Biogeographical analysis of chemical co-occurrence data to identify priorities for mixtures research
    Rogelio Tornero-Velez
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC, USA
    Risk Anal 32:224-36. 2012

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Determinants of temporal variability in NHEXAS-Maryland environmental concentrations, exposures, and biomarkers
    Peter P Egeghy
    US Environmental Protection Agency, National Exposure Research Laboratory, Human Exposure and Atmospheric Sciences Division, Research Triangle Park, NC 27711, USA
    J Expo Anal Environ Epidemiol 15:388-97. 2005
    ..Since the regression models explained only 1-37% of the within-person variance, the questionnaires in this study provided only modest insight into the factors responsible for the temporal variability in the contaminant levels...
  2. doi request reprint The exposure data landscape for manufactured chemicals
    Peter P Egeghy
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, United States
    Sci Total Environ 414:159-66. 2012
    ..Exposure to a much broader number of chemicals will need to be measured in order to fully realize the envisioned goal of using exposure information to guide toxicity testing...
  3. pmc Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population
    Bonnie R Joubert
    US Environmental Protection Agency EPA, National Exposure Research Laboratory, Durham, NC, USA
    BMC Med Genet 12:25. 2011
    ..However, methods to utilize this information to identify high risk groups are variable and replication of genetic associations in African Americans is warranted...
  4. pmc Review of pesticide urinary biomarker measurements from selected US EPA children's observational exposure studies
    Peter P Egeghy
    Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Int J Environ Res Public Health 8:1727-54. 2011
    ....
  5. doi request reprint Methodologies for estimating cumulative human exposures to current-use pyrethroid pesticides
    Nicolle S Tulve
    Office of Research and Development, National Exposure Research Laboratory, US EPA, MD E205 04, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 21:317-27. 2011
    ..g., activities, transfer coefficients, measurement techniques) are most relevant in making dermal exposure estimates...
  6. ncbi request reprint Incorporating exposure information into the toxicological prioritization index decision support framework
    Sumit Gangwal
    National Center for Computational Toxicology NCCT, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC, USA
    Sci Total Environ 435:316-25. 2012
    ..The ToxPi framework can be used to gain insight into the factors driving these rankings and aid identification of key exposure metrics. Additional exposure data is required to build confidence in exposure-based chemical prioritization...
  7. ncbi request reprint Multimedia measurements and activity patterns in an observational pilot study of nine young children
    Nicolle S Tulve
    National Exposure Research Laboratory, US EPA, MD E205 04, Research Triangle Park, NC 27711, USA
    J Expo Sci Environ Epidemiol 18:31-44. 2008
    ....
  8. ncbi request reprint Adult and children's exposure to 2,4-D from multiple sources and pathways
    Marsha K Morgan
    National Exposure Research Laboratory, USEPA, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 18:486-94. 2008
    ..In addition, our findings suggest that the OH children might have been exposed to higher levels of 2,4-D through the dermal and nondietary routes of exposure than the NC children and the NC and OH adults...
  9. ncbi request reprint American Healthy Homes Survey: a national study of residential pesticides measured from floor wipes
    Daniel M Stout
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Sci Technol 43:4294-300. 2009
    ..22 ng/cm2 and GM 0.14 ng/ cm2) and cypermethrin (mean 2.9 ng/cm2 and GM 0.03 ng/ cm2). Results show that most floors in occupied homes in the U.S. have measurable levels of insecticides that may serve as sources of exposure to occupants...
  10. doi request reprint Biogeographical analysis of chemical co-occurrence data to identify priorities for mixtures research
    Rogelio Tornero-Velez
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC, USA
    Risk Anal 32:224-36. 2012
    ..We conclude that the biogeographical tools used to determine when this structure occurs in ecological studies are relevant to evaluations of pesticide mixtures for exposure and risk assessment...
  11. doi request reprint Simple intake and pharmacokinetic modeling to characterize exposure of Americans to perfluoroctanoic acid, PFOA
    Matthew Lorber
    Office of Research and Development, United States Environmental Protection Agency, 1200 Pennsylvania Ave, NW, Washington, DC 20460, United States
    Environ Sci Technol 45:8006-14. 2011
    ..Using the PK model, the 10th and 95th percentile long-term average adult intakes of PFOA are 15 and 130 ng/day...
  12. doi request reprint Comparison of four probabilistic models (CARES(®), Calendex™, ConsExpo, and SHEDS) to estimate aggregate residential exposures to pesticides
    Bruce M Young
    Bayer CropScience, Research Triangle Park, North Carolina, USA
    J Expo Sci Environ Epidemiol 22:522-32. 2012
    ..Most of the models predicted exposures within a factor of 5 at the 50th and 99th percentiles. The differences identified are explained by activity assumptions, input distributions, and exposure algorithms...
  13. doi request reprint Pilot scale application of a method for the analysis of perfluorinated compounds in surface soils
    Mark J Strynar
    Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Chemosphere 86:252-7. 2012
    ..The resulting method shows acceptable performance characteristics for the target compounds in most soils while documenting the widespread occurrence of PFCs in surface soils...
  14. ncbi request reprint Comparing surface residue transfer efficiencies to hands using polar and nonpolar fluorescent tracers
    Elaine A Cohen Hubal
    National Center for Computational Toxicology, U S EPA, Research Triangle Park, North Carolina 27711, USA
    Environ Sci Technol 42:934-9. 2008
    ..Measurement of co-applied tracer and pesticide suggest results for these two tracers may provide reasonable bounding estimates of pesticide transfer...
  15. doi request reprint An assessment of the exposure of Americans to perfluorooctane sulfonate: a comparison of estimated intake with values inferred from NHANES data
    Peter P Egeghy
    Office of Research and Development, U S Environmental Protection Agency, National Exposure Research Laboratory, 109 TW Alexander Dr MD E205 04, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 21:150-68. 2011
    ..2 ng/kg-bw/day, and the forward-based intake estimates are within this range. The favorable comparison reported between the forward-modeled and the back-calculated range of intake predictions lends validity to the proposed framework...
  16. pmc Measuring potential dermal transfer of a pesticide to children in a child care center
    Elaine A Cohen Hubal
    National Center for Computational Toxicology, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Health Perspect 114:264-9. 2006
    ..The upper-range values resulting from this study were found to be similar to the default value used by the U.S. Environmental Protection Agency to assess children's dermal exposures resulting from contact with indoor surfaces...
  17. pmc Urinary biomarkers of exposure to jet fuel (JP-8)
    Berrin Serdar
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Environ Health Perspect 111:1760-4. 2003
    ..We conclude that urinary naphthalene and the naphthols can serve as biomarkers of exposure to jet fuel. Of these, the naphthols are probably more useful because of their greater abundance and slower elimination kinetics...
  18. ncbi request reprint Dose-dependent production of urinary naphthols among workers exposed to jet fuel (JP-8)
    Berrin Serdar
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7431, USA
    Am J Ind Med 46:234-44. 2004
    ..Jet propulsion fuel-8 (JP-8) is one of the largest sources of chemical exposures among Air Force personnel. Urinary naphthols have been suggested as useful biomarkers of exposure to JP-8...
  19. pmc Dermal exposure to jet fuel JP-8 significantly contributes to the production of urinary naphthols in fuel-cell maintenance workers
    Yi Chun E Chao
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7400, USA
    Environ Health Perspect 114:182-5. 2006
    ..Future work on dermal xenobiotic metabolism and toxicokinetic studies are warranted in order to gain additional knowledge on naphthalene metabolism in the skin and the contribution to systemic exposure...
  20. pmc PBTK modeling demonstrates contribution of dermal and inhalation exposure components to end-exhaled breath concentrations of naphthalene
    David Kim
    Department of Environmental Sciences and Engineering, School of Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7431, USA
    Environ Health Perspect 115:894-901. 2007
    ..However, a quantitative understanding of the relationship between external exposures and end-exhaled air concentrations has not been described for occupational and environmental exposure scenarios...
  21. ncbi request reprint Self-collected breath sampling for monitoring low-level benzene exposures among automobile mechanics
    Peter P Egeghy
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, 27599 7400, USA
    Ann Occup Hyg 46:489-500. 2002
    ....