Research Topics
| Peter P EgeghySummaryAffiliation: U.S. Environmental Protection Agency Country: USA Publications
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Detail Information
Publications
Determinants of temporal variability in NHEXAS-Maryland environmental concentrations, exposures, and biomarkersPeter P Egeghy
US Environmental Protection Agency, National Exposure Research Laboratory, Human Exposure and Atmospheric Sciences Division, Research Triangle Park, NC 27711, USA
J Expo Anal Environ Epidemiol 15:388-97. 2005..Since the regression models explained only 1-37% of the within-person variance, the questionnaires in this study provided only modest insight into the factors responsible for the temporal variability in the contaminant levels...
The exposure data landscape for manufactured chemicalsPeter P Egeghy
National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, United States
Sci Total Environ 414:159-66. 2012..Exposure to a much broader number of chemicals will need to be measured in order to fully realize the envisioned goal of using exposure information to guide toxicity testing...
Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban populationBonnie R Joubert
US Environmental Protection Agency EPA, National Exposure Research Laboratory, Durham, NC, USA
BMC Med Genet 12:25. 2011..However, methods to utilize this information to identify high risk groups are variable and replication of genetic associations in African Americans is warranted...- Review of pesticide urinary biomarker measurements from selected US EPA children's observational exposure studiesPeter P Egeghy
Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
Int J Environ Res Public Health 8:1727-54. 2011.... - Methodologies for estimating cumulative human exposures to current-use pyrethroid pesticidesNicolle S Tulve
Office of Research and Development, National Exposure Research Laboratory, US EPA, MD E205 04, Research Triangle Park, North Carolina 27711, USA
J Expo Sci Environ Epidemiol 21:317-27. 2011..g., activities, transfer coefficients, measurement techniques) are most relevant in making dermal exposure estimates... - Incorporating exposure information into the toxicological prioritization index decision support frameworkSumit Gangwal
National Center for Computational Toxicology NCCT, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC, USA
Sci Total Environ 435:316-25. 2012..The ToxPi framework can be used to gain insight into the factors driving these rankings and aid identification of key exposure metrics. Additional exposure data is required to build confidence in exposure-based chemical prioritization... - Multimedia measurements and activity patterns in an observational pilot study of nine young childrenNicolle S Tulve
National Exposure Research Laboratory, US EPA, MD E205 04, Research Triangle Park, NC 27711, USA
J Expo Sci Environ Epidemiol 18:31-44. 2008.... - Adult and children's exposure to 2,4-D from multiple sources and pathwaysMarsha K Morgan
National Exposure Research Laboratory, USEPA, Research Triangle Park, North Carolina 27711, USA
J Expo Sci Environ Epidemiol 18:486-94. 2008..In addition, our findings suggest that the OH children might have been exposed to higher levels of 2,4-D through the dermal and nondietary routes of exposure than the NC children and the NC and OH adults... - American Healthy Homes Survey: a national study of residential pesticides measured from floor wipesDaniel M Stout
National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
Environ Sci Technol 43:4294-300. 2009..22 ng/cm2 and GM 0.14 ng/ cm2) and cypermethrin (mean 2.9 ng/cm2 and GM 0.03 ng/ cm2). Results show that most floors in occupied homes in the U.S. have measurable levels of insecticides that may serve as sources of exposure to occupants... - Biogeographical analysis of chemical co-occurrence data to identify priorities for mixtures researchRogelio Tornero-Velez
National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC, USA
Risk Anal 32:224-36. 2012..We conclude that the biogeographical tools used to determine when this structure occurs in ecological studies are relevant to evaluations of pesticide mixtures for exposure and risk assessment... - Simple intake and pharmacokinetic modeling to characterize exposure of Americans to perfluoroctanoic acid, PFOAMatthew Lorber
Office of Research and Development, United States Environmental Protection Agency, 1200 Pennsylvania Ave, NW, Washington, DC 20460, United States
Environ Sci Technol 45:8006-14. 2011..Using the PK model, the 10th and 95th percentile long-term average adult intakes of PFOA are 15 and 130 ng/day... - Comparison of four probabilistic models (CARES(®), Calendex™, ConsExpo, and SHEDS) to estimate aggregate residential exposures to pesticidesBruce M Young
Bayer CropScience, Research Triangle Park, North Carolina, USA
J Expo Sci Environ Epidemiol 22:522-32. 2012..Most of the models predicted exposures within a factor of 5 at the 50th and 99th percentiles. The differences identified are explained by activity assumptions, input distributions, and exposure algorithms... - Pilot scale application of a method for the analysis of perfluorinated compounds in surface soilsMark J Strynar
Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
Chemosphere 86:252-7. 2012..The resulting method shows acceptable performance characteristics for the target compounds in most soils while documenting the widespread occurrence of PFCs in surface soils... - Comparing surface residue transfer efficiencies to hands using polar and nonpolar fluorescent tracersElaine A Cohen Hubal
National Center for Computational Toxicology, U S EPA, Research Triangle Park, North Carolina 27711, USA
Environ Sci Technol 42:934-9. 2008..Measurement of co-applied tracer and pesticide suggest results for these two tracers may provide reasonable bounding estimates of pesticide transfer... - An assessment of the exposure of Americans to perfluorooctane sulfonate: a comparison of estimated intake with values inferred from NHANES dataPeter P Egeghy
Office of Research and Development, U S Environmental Protection Agency, National Exposure Research Laboratory, 109 TW Alexander Dr MD E205 04, Research Triangle Park, North Carolina 27711, USA
J Expo Sci Environ Epidemiol 21:150-68. 2011..2 ng/kg-bw/day, and the forward-based intake estimates are within this range. The favorable comparison reported between the forward-modeled and the back-calculated range of intake predictions lends validity to the proposed framework... - Measuring potential dermal transfer of a pesticide to children in a child care centerElaine A Cohen Hubal
National Center for Computational Toxicology, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
Environ Health Perspect 114:264-9. 2006..The upper-range values resulting from this study were found to be similar to the default value used by the U.S. Environmental Protection Agency to assess children's dermal exposures resulting from contact with indoor surfaces... - Urinary biomarkers of exposure to jet fuel (JP-8)Berrin Serdar
Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Environ Health Perspect 111:1760-4. 2003..We conclude that urinary naphthalene and the naphthols can serve as biomarkers of exposure to jet fuel. Of these, the naphthols are probably more useful because of their greater abundance and slower elimination kinetics... - Dose-dependent production of urinary naphthols among workers exposed to jet fuel (JP-8)Berrin Serdar
Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7431, USA
Am J Ind Med 46:234-44. 2004..Smokers and nonsmokers metabolized naphthalene at different rates, consistent with induction of at least two metabolic pathways by smoking... - Dermal exposure to jet fuel JP-8 significantly contributes to the production of urinary naphthols in fuel-cell maintenance workersYi-Chun E Chao
Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7400, USA
Environ Health Perspect 114:182-5. 2006..Future work on dermal xenobiotic metabolism and toxicokinetic studies are warranted in order to gain additional knowledge on naphthalene metabolism in the skin and the contribution to systemic exposure... - PBTK modeling demonstrates contribution of dermal and inhalation exposure components to end-exhaled breath concentrations of naphthaleneDavid Kim
Department of Environmental Sciences and Engineering, School of Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7431, USA
Environ Health Perspect 115:894-901. 2007..However, a quantitative understanding of the relationship between external exposures and end-exhaled air concentrations has not been described for occupational and environmental exposure scenarios... - Self-collected breath sampling for monitoring low-level benzene exposures among automobile mechanicsPeter P Egeghy
Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, 27599-7400, USA
Ann Occup Hyg 46:489-500. 2002....