R B Devlin

Summary

Affiliation: U.S. Environmental Protection Agency
Country: USA

Publications

  1. ncbi request reprint Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash
    Yuh Chin T Huang
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Exp Lung Res 28:19-38. 2002
  2. doi request reprint In vitro determinants of asbestos fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells
    Kelly E Duncan
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U, S, Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Part Fibre Toxicol 11:2. 2014
  3. pmc Cardio-respiratory outcomes associated with exposure to wildfire smoke are modified by measures of community health
    Ana G Rappold
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, United States Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Environ Health 11:71. 2012
  4. doi request reprint Controlled exposure of healthy young volunteers to ozone causes cardiovascular effects
    Robert B Devlin
    National Health and Environmental Effects, Research Laboratory MD 58D, US EPA, Research Triangle Park, NC 27711, USA
    Circulation 126:104-11. 2012
  5. ncbi request reprint Elderly humans exposed to concentrated air pollution particles have decreased heart rate variability
    R B Devlin
    National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Eur Respir J Suppl 40:76s-80s. 2003
  6. ncbi request reprint In vitro studies: what is their role in toxicology?
    Robert B Devlin
    National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Exp Toxicol Pathol 57:183-8. 2005
  7. ncbi request reprint Inflammatory response in humans exposed to 2.0 ppm nitrogen dioxide
    R B Devlin
    Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Mail Drop 58D, Research Triangle Park, NC 27711, USA
    Inhal Toxicol 11:89-109. 1999
  8. ncbi request reprint Ozone effects on airway responsiveness, lung injury, and inflammation. Comparative rat strain and in vivo/in vitro investigations
    J A Dye
    U S Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, ETD, PTB, MD 82, Research Triangle Park, NC 27711
    Inhal Toxicol 11:1015-40. 1999
  9. pmc Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress
    Susanne Becker
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 113:1032-8. 2005
  10. ncbi request reprint Neuropeptides and capsaicin stimulate the release of inflammatory cytokines in a human bronchial epithelial cell line
    B Veronesi
    National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Neuropeptides 33:447-56. 1999

Detail Information

Publications53

  1. ncbi request reprint Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash
    Yuh Chin T Huang
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Exp Lung Res 28:19-38. 2002
    ..These results indicate that tyrosine phosphorylation of EGF receptors in the lung, possibly as a result of inhibition of protein tyrosine phosphatases, mediates constriction of pulmonary vessels induced by ROFA...
  2. doi request reprint In vitro determinants of asbestos fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells
    Kelly E Duncan
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U, S, Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Part Fibre Toxicol 11:2. 2014
    ..The composition of Libby amphibole (LA) is complex and minimal toxicity data are available. In this study, we conduct a comparative particle toxicity analysis of LA compared with standard reference asbestiform amphibole samples...
  3. pmc Cardio-respiratory outcomes associated with exposure to wildfire smoke are modified by measures of community health
    Ana G Rappold
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, United States Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Environ Health 11:71. 2012
    ..We evaluate general and specific measures of community health as modifiers of risk for asthma and congestive heart failure following an episode of acute exposure to wildfire smoke...
  4. doi request reprint Controlled exposure of healthy young volunteers to ozone causes cardiovascular effects
    Robert B Devlin
    National Health and Environmental Effects, Research Laboratory MD 58D, US EPA, Research Triangle Park, NC 27711, USA
    Circulation 126:104-11. 2012
    ..In contrast, for ozone, almost no controlled-human-exposure studies have tested whether ozone exposure can modulate the cardiovascular system...
  5. ncbi request reprint Elderly humans exposed to concentrated air pollution particles have decreased heart rate variability
    R B Devlin
    National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Eur Respir J Suppl 40:76s-80s. 2003
    ....
  6. ncbi request reprint In vitro studies: what is their role in toxicology?
    Robert B Devlin
    National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Exp Toxicol Pathol 57:183-8. 2005
    ..This coherence between an in vivo and in vitro response provides relevance to additional in vitro studies that characterize the mechanisms by which these particles cause adverse health effects...
  7. ncbi request reprint Inflammatory response in humans exposed to 2.0 ppm nitrogen dioxide
    R B Devlin
    Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Mail Drop 58D, Research Triangle Park, NC 27711, USA
    Inhal Toxicol 11:89-109. 1999
    ..05) decrease in the fraction of aerosol recovered following nitrogen dioxide exposure, which is suggestive of small obstructive changes induced by NO2...
  8. ncbi request reprint Ozone effects on airway responsiveness, lung injury, and inflammation. Comparative rat strain and in vivo/in vitro investigations
    J A Dye
    U S Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, ETD, PTB, MD 82, Research Triangle Park, NC 27711
    Inhal Toxicol 11:1015-40. 1999
    ..Results demonstrate that multiple inflammatory mediator pathways are affected by ozone exposure. Such effects could exacerbate morbidity in individuals with preexisting airway inflammation such as asthmatics...
  9. pmc Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress
    Susanne Becker
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 113:1032-8. 2005
    ..These results indicate that elemental constituents of PM may in part account for the seasonal variations in PM-induced adverse health effects related to lung inflammation...
  10. ncbi request reprint Neuropeptides and capsaicin stimulate the release of inflammatory cytokines in a human bronchial epithelial cell line
    B Veronesi
    National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Neuropeptides 33:447-56. 1999
    ....
  11. ncbi request reprint Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers
    A J Ghio
    National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Am J Respir Crit Care Med 162:981-8. 2000
    ..We conclude that ambient air particles are capable of inducing a mild inflammation in the lower respiratory tract, as well as an increased concentration of blood fibrinogen...
  12. ncbi request reprint Inflammatory lung injury after bronchial instillation of air pollution particles
    A J Ghio
    Clinical Research Branch, Human Studies Division, National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, North Carolina 27599 7315, USA
    Am J Respir Crit Care Med 164:704-8. 2001
    ..Findings suggest that mass may not be the most appropriate metric to use in assessing health effects after PM exposure but rather specific components must be identified and assessed...
  13. ncbi request reprint Time-dependent changes of markers associated with inflammation in the lungs of humans exposed to ambient levels of ozone
    H S Koren
    Health Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711
    Toxicol Pathol 19:406-11. 1991
    ..These changes were detectable as early as 1 hr following a 2 hr exposure of humans to ozone. The profiles of these changes were different at 1 hr and 18 hr following ozone exposures.(ABSTRACT TRUNCATED AT 250 WORDS)..
  14. pmc Inhalation of PM2.5 does not modulate host defense or immune parameters in blood or lung of normal human subjects
    S D Harder
    National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 109:599-604. 2001
    ..We conclude that ambient air particles are capable of inducing a mild inflammation in the lower respiratory tract but have no effect on immune phenotype or macrophage function under the conditions tested...
  15. ncbi request reprint Respiratory epithelial cells demonstrate lactoferrin receptors that increase after metal exposure
    A J Ghio
    National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Am J Physiol 276:L933-40. 1999
    ..We conclude that LfRs on respiratory epithelial cells increased after exposure to metal. LfRs could participate in decreasing the oxidative stress presented to the lower respiratory tract by complexing catalytically active metals...
  16. ncbi request reprint Exposure to air pollution is associated with lung hyperinflation in healthy children and adolescents in Southwest Mexico City: a pilot study
    L Calderon-Garciduenas
    Curriculum in Toxicology, University of North Carolina, Chapel Hill, USA
    Inhal Toxicol 12:537-61. 2000
    ..Our main concern is the potential likelihood for the development of chronic lung disease in this highly exposed population...
  17. ncbi request reprint Canines as sentinel species for assessing chronic exposures to air pollutants: part 2. Cardiac pathology
    L Calderon-Garciduenas
    Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina 27599 7310, USA
    Toxicol Sci 61:356-67. 2001
    ....
  18. ncbi request reprint Nasal biopsies of children exposed to air pollutants
    L Calderon-Garciduenas
    University of North Carolina, Chapel Hill 27514, USA
    Toxicol Pathol 29:558-64. 2001
    ..Parents should be advised to decrease the children's number of outdoor exposure hours and encourage a balanced diet with an important component of fresh fruits and vegetables...
  19. ncbi request reprint Ultrastructural nasal pathology in children chronically and sequentially exposed to air pollutants
    L Calderon-Garciduenas
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Am J Respir Cell Mol Biol 24:132-8. 2001
    ..Chronic exposures to air pollutants affect the whole respiratory tract; the nasal epithelium is an accessible and valuable sentinel to monitor exposures to toxic or carcinogenic substances...
  20. ncbi request reprint Respiratory tract pathology and cytokine imbalance in clinically healthy children chronically and sequentially exposed to air pollutants
    L Calderon-Garciduenas
    Curriculum in Toxicology, University of North Carolina at Chapel Hill, NC, USA
    Med Hypotheses 55:373-8. 2000
    ..Cytokines likely would reach the systemic circulation and produce systemic effects. Individuals with an underlying respiratory or cardiovascular disease are less able to maintain equilibrium of the precarious cytokine networks...
  21. ncbi request reprint Canines as sentinel species for assessing chronic exposures to air pollutants: part 1. Respiratory pathology
    L Calderon-Garciduenas
    Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina, USA
    Toxicol Sci 61:342-55. 2001
    ..Deep concern exists for the potential of an increasing rise in lung diseases in child populations exposed to Mexico City's environment...
  22. ncbi request reprint Comparative toxicity of size-fractionated airborne particulate matter obtained from different cities in the United States
    M Ian Gilmour
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Durham, North Carolina 27711, USA
    Inhal Toxicol 19:7-16. 2007
    ..Further studies will assess how source profiles correlate with the observed effects for all locations and size fractions...
  23. ncbi request reprint A comparison of studies on the effects of controlled exposure to fine, coarse and ultrafine ambient particulate matter from a single location
    James M Samet
    Human Studies Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27514, USA
    Inhal Toxicol 19:29-32. 2007
    ..These findings have relevant implications for the design of future chamber studies and the role of particle size fraction in the adverse health effects of PM exposure in humans...
  24. ncbi request reprint Source apportionment of particulate matter in the U.S. and associations with lung inflammatory markers
    Rachelle M Duvall
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Inhal Toxicol 20:671-83. 2008
    ..Increases in inflammatory markers were not observed for coarse PM mass and source markers. These findings suggest that certain PM size fractions and sources are associated with markers of lung injury or inflammation...
  25. doi request reprint Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice
    Haiyan Tong
    Human Studies Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 239:224-32. 2009
    ..Further experiments are needed to understand the physico-chemical processes involved in this phenomenon...
  26. doi request reprint Differential cardiopulmonary effects of size-fractionated ambient particulate matter in mice
    Haiyan Tong
    Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Cardiovasc Toxicol 10:259-67. 2010
    ..This study shows that exposure of mice to coarse PM results in significant pulmonary toxicity while ultrafine PM appears to enhance cardiac ischemia/reperfusion injury...
  27. pmc Lung function and inflammatory responses in healthy young adults exposed to 0.06 ppm ozone for 6.6 hours
    Chong S Kim
    Environmental Public Health Division MD 58B, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Am J Respir Crit Care Med 183:1215-21. 2011
    ..Exposure to ozone causes a decrease in spirometric lung function and an increase in airway inflammation in healthy young adults at concentrations as low as 0.08 ppm, close to the National Ambient Air Quality Standard for ground level ozone...
  28. ncbi request reprint TLR-2 is involved in airway epithelial cell response to air pollution particles
    Susanne Becker
    Clinical Research Branch, Human Studies Division, National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 203:45-52. 2005
    ..Hsp70 was increased by PM(2.5-10) > PM2.5 > UF PM suggesting the possibility of indirect activation of TLR pathway by this endogenous TLR2/4 agonist...
  29. doi request reprint Concentrated ambient ultrafine particle exposure induces cardiac changes in young healthy volunteers
    James M Samet
    Human Studies Division, National Health and Environmental Effects Research Laboratory, Research Triangle Park, Chapel Hill, NC 27599 7315, USA
    Am J Respir Crit Care Med 179:1034-42. 2009
    ..Exposure to ambient ultrafine particles has been associated with cardiopulmonary toxicity and mortality. Adverse effects specifically linked to ultrafine particles include loss of sympathovagal balance and altered hemostasis...
  30. ncbi request reprint The role of soluble components in ambient fine particles-induced changes in human lungs and blood
    Yuh Chin T Huang
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC, USA
    Inhal Toxicol 15:327-42. 2003
    ....
  31. ncbi request reprint Exposure to concentrated ambient air particles alters hematologic indices in humans
    Andrew J Ghio
    National Health and Environmental Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Inhal Toxicol 15:1465-78. 2003
    ..We conclude that exposure of healthy volunteers to CAPs can be associated with decreases of both white blood cell (WBC) count and LDH and increased concentrations of fibrinogen in the blood...
  32. pmc Metal particulate matter components affect gene expression and beat frequency of neonatal rat ventricular myocytes
    Donald W Graff
    National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Health Perspect 112:792-8. 2004
    ..As such, these data suggest that the cardiac effects of PM are largely determined by the relative metal composition of particles...
  33. ncbi request reprint Effect of antioxidant supplementation on ozone-induced lung injury in human subjects
    J M Samet
    Human Studies Division, National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, USA
    Am J Respir Crit Care Med 164:819-25. 2001
    ..These data suggest that dietary antioxidants protect against O(3)-induced pulmonary function decrements in humans...
  34. ncbi request reprint Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: further mechanistic studies
    Susanne Becker
    US Environmental Protection Agency, Human Studies Facility, National Health and Environmental Effects Research Laboratory, Research Triangle Park, 104 Mason Farm Road, Chapel Hill, NC 27599, USA
    Toxicol Appl Pharmacol 207:269-75. 2005
    ..Exposure to coarse and fine PM decreased the expression of TLR4 in the macrophages. Particle-induced decrease in TLR4 and hyporesponsiveness to LPS may be related to LPS tolerance induced by low levels of LPS...
  35. pmc Identification of subpopulations that are sensitive to ozone exposure: use of end points currently available and potential use of laboratory-based end points under development
    R B Devlin
    Health Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711
    Environ Health Perspect 101:225-30. 1993
    ..It also describes potential new sensitive end points that might be available for ozone epidemiology studies in the near future...
  36. ncbi request reprint Transcriptional profiling of mucociliary differentiation in human airway epithelial cells
    Andrea J Ross
    Clinical Research Branch, Human Studies Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, University of North Carolina, Chapel Hill, North Carolina 27599 7315, USA
    Am J Respir Cell Mol Biol 37:169-85. 2007
    ..This work has provided extensive information about gene expression changes during differentiation of airway epithelial cells, and will be a useful resource for researchers interested in respiratory function, pathology, and toxicology...
  37. ncbi request reprint Diffuse alveolar damage after exposure to an oil fly ash
    A J Ghio
    National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Am J Respir Crit Care Med 164:1514-8. 2001
    ..This patient presents with the aggregate of potential injuries described by epidemiological methods to be associated with air pollution particle exposure...
  38. ncbi request reprint Induction of DNA strand breaks by trihalomethanes in primary human lung epithelial cells
    Stefano Landi
    US Environmental Protection Agency, National Health and Environmental, Effects Research Laboratory, Research Triangle Park, NC 27711, USA
    Mutat Res 538:41-50. 2003
    ....
  39. ncbi request reprint Ozone enhances markers of innate immunity and antigen presentation on airway monocytes in healthy individuals
    John C Lay
    J Allergy Clin Immunol 120:719-22. 2007
  40. ncbi request reprint Exposures of elderly volunteers with and without chronic obstructive pulmonary disease (COPD) to concentrated ambient fine particulate pollution
    Henry Gong
    Los Amigos Research and Education Institute, Downey, California 90242, USA
    Inhal Toxicol 16:731-44. 2004
    ..Unexpectedly, individuals with COPD appeared less susceptible than healthy elderly individuals. Further investigation of older adults is warranted to understand the pathophysiology and public health significance of these findings...
  41. ncbi request reprint Particulate matter exposure in cars is associated with cardiovascular effects in healthy young men
    Michael Riediker
    Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, USA
    Am J Respir Crit Care Med 169:934-40. 2004
    ..5) were smaller and less significant. The observations in these healthy young men suggest that in-vehicle exposure to PM(2.5) may cause pathophysiologic changes that involve inflammation, coagulation, and cardiac rhythm...
  42. ncbi request reprint Ultrafine particulate matter exposure augments ischemia-reperfusion injury in mice
    Emily Cozzi
    Department of Physiology, Brody School of Medicine, East Carolina Univ, 6N98 Brody Bldg, Greenville, NC 27834, USA
    Am J Physiol Heart Circ Physiol 291:H894-903. 2006
    ..These results indicate that exposure to ultrafine PM increases oxidative stress in the myocardium, alters vascular reactivity, and augments injury after I/R in a murine model...
  43. pmc Discrimination of vanadium from zinc using gene profiling in human bronchial epithelial cells
    Zhuowei Li
    Center for Environmental Medicine and Lung Biology, University of North Carolina, Chapel Hill, North Carolina, USA
    Environ Health Perspect 113:1747-54. 2005
    ..The novel genes and pathways identified by the microarray may help us understand the pathogenesis of health effects caused by environmental V and Zn exposure...
  44. ncbi request reprint Cardiovascular effects associated with air pollution: potential mechanisms and methods of testing
    Mark J Utell
    Department of Medicine, University of Rochester Medical Center, Pulmonary Division, Box 692, Rochester, NY, USA
    Inhal Toxicol 14:1231-47. 2002
    ..A variety of approaches ranging from molecular and genetic investigations to human clinical studies were recommended to further investigate the important epidemiologic associations...
  45. ncbi request reprint Iron homeostasis in the lung following asbestos exposure
    Andrew J Ghio
    Antioxid Redox Signal 10:371-7. 2008
    ..Based on these findings, we propose a model of oxidative stress and human lung injury after asbestos exposure...
  46. ncbi request reprint Biological material on inhaled coarse fraction particulate matter activates airway phagocytes in vivo in healthy volunteers
    Neil E Alexis
    Center for Environmental Medicine Asthma and Lung Biology, University of North Carolina at Chapel Hill, NC 27599 7310, USA
    J Allergy Clin Immunol 117:1396-403. 2006
    ..In vitro, endotoxin on coarse fraction particulate matter (PM2.5-10) accounts for the majority of the ability of PM2.5-10 to induce cytokine responses from alveolar macrophages...
  47. ncbi request reprint Effect of ambient particulate matter exposure on hemostasis
    Emily Cozzi
    Department of Physiology, Brody School of Medicine at East Carolina University, Greenville, NC 27834, USA
    Transl Res 149:324-32. 2007
    ..The results also establish definite hemostatic endpoints that can be used to further investigate the effects of dose and particle characteristics on the toxicity of ambient particles...
  48. ncbi request reprint Assessing the role of particulate matter size and composition on gene expression in pulmonary cells
    Donald W Graff
    MDS Pharma Services, Inc, Lincoln, Nebraska 68521, USA
    Inhal Toxicol 19:23-8. 2007
    ..The ultimate goal of this line of research is to link the mechanistic data to the PM source data in order to gain an understanding about how the components and sources of PM affect human health...
  49. ncbi request reprint Exposures of healthy and asthmatic volunteers to concentrated ambient ultrafine particles in Los Angeles
    Henry Gong
    Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Inhal Toxicol 20:533-45. 2008
    ....
  50. ncbi request reprint Cardiac and vascular changes in mice after exposure to ultrafine particulate matter
    Wayne E Cascio
    Department of Medicine, Brody School of Medicine at East Carolina University, Greenville, North Carolina 27834, USA
    Inhal Toxicol 19:67-73. 2007
    ....
  51. ncbi request reprint Killing of Klebsiella pneumoniae by human alveolar macrophages
    Judy M Hickman-Davis
    Department of Anesthesiology, Division of Nephrology and Nephrology Research Training Center, School of Medicine, University of Alabama at Birmingham, 35294, USA
    Am J Physiol Lung Cell Mol Physiol 282:L944-56. 2002
    ..4. These findings indicate that SP-A mediates pathogen killing by AMs from transplant lungs by stimulating phagocytosis and production of reactive oxygen-nitrogen intermediates...
  52. ncbi request reprint Effect of the September 11, 2001 terrorist attack on a state highway patrol trooper's heart rate variability
    Michael Riediker
    Center for Environmental Medicine, Asthma and Lung Biology School of Medicine, University of North Carolina, Chapel Hill, NC, USA
    Ann Noninvasive Electrocardiol 10:83-5. 2005
    ..On September 11, 2001, terrorists attacked the United States. By coincidence, a North Carolina highway patrol trooper was wearing an ambulatory ECG Holter monitor at this time as part of an air pollution study...
  53. pmc Coarse particulate matter (PM2.5-10) affects heart rate variability, blood lipids, and circulating eosinophils in adults with asthma
    Karin Yeatts
    Center for Environmental Medicine, Asthma, and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina 27599 7310, USA
    Environ Health Perspect 115:709-14. 2007
    ..5-10 microm (PM(2.5-10))] and fine (PM(2.5)) size range...