Kimberly A Zuhlke

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer
    Kimberly A Zuhlke
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
    Fam Cancer 11:595-600. 2012
  2. pmc Genetic variation in glutathione S-transferase omega-1, arsenic methyltransferase and methylene-tetrahydrofolate reductase, arsenic exposure and bladder cancer: a case-control study
    Jennifer L Beebe-Dimmer
    Program of Population Studies and Disparities Research, Karmanos Cancer Institute, 4100 John R, Detroit, MI 48201, USA
    Environ Health 11:43. 2012
  3. ncbi request reprint Identification of a novel germline SPOP mutation in a family with hereditary prostate cancer
    Kimberly A Zuhlke
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
    Prostate 74:983-90. 2014
  4. pmc Chromosome 17q12 variants contribute to risk of early-onset prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 5618, USA
    Cancer Res 68:6492-5. 2008
  5. pmc Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy
    Jennifer L Beebe-Dimmer
    Department of Oncology, Wayne State University, Detroit, MI, USA Barbara Ann Karmanos Cancer Institute, Population Studies and Disparities Research Program, Detroit, MI, USA
    BJU Int 113:830-5. 2014
  6. pmc HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey
    Steven C Smith
    Departments of Pathology Internal Medicine Urology Michigan Center for Translational Pathology Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI Howard Hughes Medical Institute, Chevy Chase, MD
    Am J Surg Pathol 38:615-26. 2014
  7. pmc Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men
    Anna M Ray
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Prostate 69:956-60. 2009
  8. pmc Chromosome 8q24 markers: risk of early-onset and familial prostate cancer
    Jennifer L Beebe-Dimmer
    Karmanos Cancer Institute and Wayne State University, Detroit, MI, USA
    Int J Cancer 122:2876-9. 2008
  9. doi request reprint Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy
    Florian R Schroeck
    Division of Health Services Research, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    J Urol 189:849-53. 2013
  10. ncbi request reprint Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109 0618, USA
    Prostate 67:1507-13. 2007

Collaborators

Detail Information

Publications10

  1. pmc Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer
    Kimberly A Zuhlke
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
    Fam Cancer 11:595-600. 2012
    ..The S706X mutation truncates the protein in a highly conserved region of NBN near the MRE11 binding site, thus suggesting a role for rare NBN mutations in prostate cancer susceptibility...
  2. pmc Genetic variation in glutathione S-transferase omega-1, arsenic methyltransferase and methylene-tetrahydrofolate reductase, arsenic exposure and bladder cancer: a case-control study
    Jennifer L Beebe-Dimmer
    Program of Population Studies and Disparities Research, Karmanos Cancer Institute, 4100 John R, Detroit, MI 48201, USA
    Environ Health 11:43. 2012
    ..Therefore, we examined the association between genes thought to play a role in the metabolism of arsenic and bladder cancer...
  3. ncbi request reprint Identification of a novel germline SPOP mutation in a family with hereditary prostate cancer
    Kimberly A Zuhlke
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
    Prostate 74:983-90. 2014
    ..SPOP (Speckle-type POZ protein) maps to the 17q21-22 candidate linkage region and is one of the most frequently mutated genes in sporadic prostate cancers...
  4. pmc Chromosome 17q12 variants contribute to risk of early-onset prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 5618, USA
    Cancer Res 68:6492-5. 2008
    ..Thus, there likely exist one or more additional independent prostate cancer susceptibility loci in this region...
  5. pmc Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy
    Jennifer L Beebe-Dimmer
    Department of Oncology, Wayne State University, Detroit, MI, USA Barbara Ann Karmanos Cancer Institute, Population Studies and Disparities Research Program, Detroit, MI, USA
    BJU Int 113:830-5. 2014
    ..To determine the prevalence and clinical correlates of the G84E mutation in the homeobox transcription factor, or HOXB13, gene using DNA samples from 9559 men with prostate cancer undergoing radical prostatectomy...
  6. pmc HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey
    Steven C Smith
    Departments of Pathology Internal Medicine Urology Michigan Center for Translational Pathology Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI Howard Hughes Medical Institute, Chevy Chase, MD
    Am J Surg Pathol 38:615-26. 2014
    ..These findings suggest that novel molecular pathways may drive disease in HOXB13 G84E carriers. ..
  7. pmc Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men
    Anna M Ray
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Prostate 69:956-60. 2009
    ..Here we examine the association between COI mutations and PCa in African American men...
  8. pmc Chromosome 8q24 markers: risk of early-onset and familial prostate cancer
    Jennifer L Beebe-Dimmer
    Karmanos Cancer Institute and Wayne State University, Detroit, MI, USA
    Int J Cancer 122:2876-9. 2008
    ..In addition, our results suggest that the increased risk associated with these SNPs is approximately doubled in individuals predisposed to develop early onset or clinically aggressive disease...
  9. doi request reprint Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy
    Florian R Schroeck
    Division of Health Services Research, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    J Urol 189:849-53. 2013
    ..We estimated the prevalence of this mutation in a clinical population of men at risk for prostate cancer who were scheduled to undergo prostate biopsy...
  10. ncbi request reprint Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109 0618, USA
    Prostate 67:1507-13. 2007
    ..An initial study has also suggested that the risk of familial (but not sporadic) prostate cancer may be associated with germline variation in the AMACR gene...