Jordanka Zlatanova

Summary

Affiliation: University of Wyoming
Country: USA

Publications

  1. pmc Assembly of single chromatin fibers depends on the tension in the DNA molecule: magnetic tweezers study
    Sanford H Leuba
    Department of Cell Biology and Physiology, School of Medicine, Hillman Cancer Center, University of Pittsburgh Cancer Institute Research Pavilion, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 100:495-500. 2003
  2. ncbi request reprint Single-molecule analysis of chromatin
    Sanford H Leuba
    Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Hillman Cancer Center, UPCI Research Pavilion, Pennsylvania 15213 1863, USA
    Methods Enzymol 376:73-105. 2004
  3. ncbi request reprint Single-molecule biology: what is it and how does it work?
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, Wyoming 82071, USA
    Mol Cell 24:317-29. 2006
  4. pmc Pulling chromatin apart: Unstacking or Unwrapping?
    Jean Marc Victor
    Laboratory for Theoretical Physics of Condensed Matter, UPMC, 75005 Paris, France
    BMC Biophys 5:21. 2012
  5. doi request reprint The linker-protein network: control of nucleosomal DNA accessibility
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    Trends Biochem Sci 33:247-53. 2008
  6. doi request reprint CCCTC-binding factor: to loop or to bridge
    J Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    Cell Mol Life Sci 66:1647-60. 2009
  7. ncbi request reprint Nap1: taking a closer look at a juggler protein of extraordinary skills
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    FASEB J 21:1294-310. 2007
  8. ncbi request reprint Single-molecule approaches reveal the idiosyncrasies of RNA polymerases
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, Wyoming 82071, USA
    Structure 14:953-66. 2006
  9. doi request reprint The nucleosome family: dynamic and growing
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    Structure 17:160-71. 2009
  10. doi request reprint CTCF and its protein partners: divide and rule?
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    J Cell Sci 122:1275-84. 2009

Collaborators

  • Paola Caiafa
  • Sanford H Leuba
  • J Ausio
  • K Fukui
  • THOMAS CONNOR BISHOP
  • J D Parvin
  • Oleg Laptenko
  • Julia N Yaneva
  • Miroslav Tomschik
  • Amit Thakar
  • Satoru Fujimoto
  • Pooja Gupta
  • Ken van Holde
  • Corrine Seebart
  • Jean Marc Victor
  • Jessica Prenni
  • PEDRO RODRIGUEZ-COLLAZO
  • William T McAllister
  • Kensal van Holde
  • Richard T Pomerantz
  • Julien Mozziconacci
  • Maria Barbi
  • Tiziana Guastafierro
  • Begonia Silva-Moreno
  • Toyotaka Ishibashi
  • Susumu Uchiyama
  • Ron Finn
  • Rebecca C Chiffer
  • Catharine L Smith
  • Sara K Snyder
  • Christophe Place
  • Michael Anikin
  • Zoher Gueroui
  • Haocheng Zheng
  • Ravi Ramjit

Detail Information

Publications31

  1. pmc Assembly of single chromatin fibers depends on the tension in the DNA molecule: magnetic tweezers study
    Sanford H Leuba
    Department of Cell Biology and Physiology, School of Medicine, Hillman Cancer Center, University of Pittsburgh Cancer Institute Research Pavilion, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 100:495-500. 2003
    ..This result is a clear demonstration of the dynamic equilibrium between nucleosome assembly and disassembly at the single chromatin fiber level...
  2. ncbi request reprint Single-molecule analysis of chromatin
    Sanford H Leuba
    Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Hillman Cancer Center, UPCI Research Pavilion, Pennsylvania 15213 1863, USA
    Methods Enzymol 376:73-105. 2004
  3. ncbi request reprint Single-molecule biology: what is it and how does it work?
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, Wyoming 82071, USA
    Mol Cell 24:317-29. 2006
    ..Perhaps most important is the emerging ability to carry out such observations and manipulations within the living cell. The long-awaited leap to an in vivo biochemistry is at last underway...
  4. pmc Pulling chromatin apart: Unstacking or Unwrapping?
    Jean Marc Victor
    Laboratory for Theoretical Physics of Condensed Matter, UPMC, 75005 Paris, France
    BMC Biophys 5:21. 2012
    ..abstract:..
  5. doi request reprint The linker-protein network: control of nucleosomal DNA accessibility
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    Trends Biochem Sci 33:247-53. 2008
    ..Finally, according to our proposed model, the exchange factors are themselves controlled by post-translational modifications or binding of protein partners, to respond to the ever-changing intra- and extra-cellular environment...
  6. doi request reprint CCCTC-binding factor: to loop or to bridge
    J Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    Cell Mol Life Sci 66:1647-60. 2009
    ..The thousands of CTCF binding sites, identified in recent genome-wide localization studies, and their distribution along the genome further support a crucial role of CTCF as a chromatin organizer...
  7. ncbi request reprint Nap1: taking a closer look at a juggler protein of extraordinary skills
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    FASEB J 21:1294-310. 2007
    ..Why nature endowed this specific protein with so many functions may remain a mystery. We are aware of the enormous challenge to the scientific community that understanding the mechanisms underlying these activities presents...
  8. ncbi request reprint Single-molecule approaches reveal the idiosyncrasies of RNA polymerases
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, Wyoming 82071, USA
    Structure 14:953-66. 2006
    ..This review discusses methods and results from this emerging field, and it puts them in perspective of existing biochemical and structural data...
  9. doi request reprint The nucleosome family: dynamic and growing
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    Structure 17:160-71. 2009
    ..quot; The nucleosome can no longer be viewed as a single static entity: rather, it is a family of particles differing in their structural and dynamic properties, leading to different functionalities...
  10. doi request reprint CTCF and its protein partners: divide and rule?
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    J Cell Sci 122:1275-84. 2009
    ..We propose that CTCF interacts with one or two different partners according to the biological context, applying the Roman principle of governance, 'divide and rule' (divide et impera)...
  11. ncbi request reprint MeCP2: the chromatin connection and beyond
    Jordanka Zlatanova
    Department of Molecular Biology, College of Agriculture, University of Wyoming, Laramie, WY 82071, USA
    Biochem Cell Biol 83:251-62. 2005
    ..Finally, the newly established facts concerning the connection of MeCP2 to human disease are presented...
  12. doi request reprint H2A.Z: view from the top
    Jordanka Zlatanova
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    Structure 16:166-79. 2008
    ..Z, a player with a variety of seemingly unrelated, even contrary, functions. This attempt was prompted by the recent avalanche of genome-wide studies that provide insights that were unthinkable until very recently...
  13. doi request reprint H2A.Z and H3.3 histone variants affect nucleosome structure: biochemical and biophysical studies
    Amit Thakar
    Department of Molecular Biology, University of Wyoming, Laramie, Wyoming 82071, USA
    Biochemistry 48:10852-7. 2009
    ..Z-containing nucleosomes exhibit altered linker histone binding. These properties could be physiologically significant as nucleosome positions and linker histone binding partly determine factor binding accessibility...
  14. doi request reprint Proteome analysis of protein partners to nucleosomes containing canonical H2A or the variant histones H2A.Z or H2A.X
    Satoru Fujimoto
    Department of Molecular Biology, College of Agriculture, University of Wyoming, 1000 E University Ave, Laramie, WY 82071, USA
    Biol Chem 393:47-61. 2012
    ..To our knowledge, our data represent the first systematic analysis of the H2A.Z and H2A.X interactome in the context of nucleosome structure...
  15. doi request reprint Histone variant H2A.Z inhibits transcription in reconstituted nucleosomes
    Amit Thakar
    Department of Molecular Biology, University of Wyoming, Laramie, Wyoming 82071, USA
    Biochemistry 49:4018-26. 2010
    ..To our knowledge, this is the first example of a nucleosome that is intrinsically untranscribable...
  16. pmc Nucleosome assembly depends on the torsion in the DNA molecule: a magnetic tweezers study
    Pooja Gupta
    Department of Molecular Biology, University of Wyoming, Laramie, Wyoming, USA
    Biophys J 97:3150-7. 2009
    ..We conclude that levels of positive supercoiling in the range of 0.025-0.051 (most probably in the form of twist) stall the nucleosome assembly process...
  17. doi request reprint New nuclear partners for nucleosome assembly protein 1: unexpected associations
    Corrine Seebart
    Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
    Biochem Cell Biol 88:927-36. 2010
    ..These studies represent a starting point for further investigation of Nap1 associations in human cells...
  18. pmc Does BLM helicase unwind nucleosomal DNA?
    Satoru Fujimoto
    Department of Molecular Biology, College of Agriculture, University of Wyoming, 1000 East University Ave, Laramie, WY 82071, USA
    Biochem Cell Biol 87:875-82. 2009
    ..These results indicate that full-length BLM may require additional factors to unwind nucleosomal DNA in vivo, and that RPA is, on its own, unable to perform this auxiliary function...
  19. doi request reprint Nucleosome dynamics as studied by single-pair fluorescence resonance energy transfer: a reevaluation
    Miroslav Tomschik
    Department of Molecular Biology, College of Agriculture, University of Wyoming, Laramie, WY 82071, USA
    J Fluoresc 19:53-62. 2009
    ..There is, nevertheless, evidence for the existence of infrequent, rapid opening events...
  20. ncbi request reprint BRCA1/BARD1 E3 ubiquitin ligase can modify histones H2A and H2B in the nucleosome particle
    Amit Thakar
    Dept of Molecular Biology University of Wyoming, Laramie, WY 82071, USA
    J Biomol Struct Dyn 27:399-406. 2010
    ..These results raise the possibility that BRCA1/BARD1 can directly affect nucleosomal structure, dynamics, and function through its ability to modify nucleosomal histones...
  21. ncbi request reprint Chromatin fibers, one-at-a-time
    Jordanka Zlatanova
    Department of Chemistry and Chemical Engineering, Polytechnic University, 6 Metro Tech Center, Brooklyn, NY 11201, USA
    J Mol Biol 331:1-19. 2003
    ..The beginning is exciting and promising, but much more effort will be needed to take advantage of the huge potential that the new physics-based techniques offer...
  22. ncbi request reprint Magnetic tweezers: a sensitive tool to study DNA and chromatin at the single-molecule level
    Jordanka Zlatanova
    Department of Chemistry and Chemicl Engineering, Polytechnic University, Brooklyn, New York 11201, USA
    Biochem Cell Biol 81:151-9. 2003
    ..Its potential for chromatin studies is also enormous, and we will briefly present our first chromatin results...
  23. ncbi request reprint Forcing chromatin
    Jordanka Zlatanova
    Departments of Chemical and Biological Sciences and Engineering, Polytechnic University, Brooklyn, New York 11101, USA
    J Biol Chem 278:23213-6. 2003
  24. pmc Fast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer
    Miroslav Tomschik
    Department of Cell Biology and Physiology, Hillman Cancer Center, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 102:3278-83. 2005
    ..The brief excursions into an extended open state may create windows of opportunity for protein factors involved in DNA transactions to bind to or translocate along the DNA...
  25. ncbi request reprint Scanning chromatin: a new paradigm?
    Kensal van Holde
    Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, USA
    J Biol Chem 281:12197-200. 2006
  26. ncbi request reprint Chromatin fiber structure: Where is the problem now?
    Ken van Holde
    Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
    Semin Cell Dev Biol 18:651-8. 2007
    ..In this chapter, we briefly review the older conjectures and some more recent studies of special interest. We attempt to point out the remaining contradictions and hopeful lines of future research...
  27. ncbi request reprint Stretching and imaging single DNA molecules and chromatin
    Jordanka Zlatanova
    Department of Chemistry and Chemical Engineering, Polytechnic University, Brooklyn, NY 11201, USA
    J Muscle Res Cell Motil 23:377-95. 2002
    ....
  28. ncbi request reprint Single-molecule studies of chromatin fibers: a personal report
    Sanford H Leuba
    Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Hillman Cancer Center, Pittsburgh, PA 15213, USA
    Arch Histol Cytol 65:391-403. 2002
    ..We believe that our results so far have contributed significantly to our understanding of chromatin, but we also hope that this is only the beginning, and that more exciting times lie ahead...
  29. ncbi request reprint Histone H1 interacts preferentially with DNA fragments containing a cisplatin-induced 1,2-intrastrand cross-link
    Julia N Yaneva
    Department of Gene Regulations, Institute of Molecular Biology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria
    Z Naturforsch C 62:905-8. 2007
    ..The experimental data throw light on the precise preference of histone H1 for binding to different types of cisplatin-created cross-links in DNA...
  30. ncbi request reprint A tightly regulated molecular motor based upon T7 RNA polymerase
    Richard T Pomerantz
    Department of Microbiology and Immunology and Graduate Program in Molecular and Cellular Biology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, New York 11203 2098, USA
    Nano Lett 5:1698-703. 2005
    ..Using single-molecule methods, we visualize the assembly and manipulation of nanodevices and the ability to harness rotary and linear forces of the RNAP motor...
  31. ncbi request reprint cAMP signaling induces rapid loss of histone H3 phosphorylation in mammary adenocarcinoma-derived cell lines
    PEDRO RODRIGUEZ-COLLAZO
    Signal Transduction Group, Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, MD 20895, USA
    Exp Cell Res 314:1-10. 2008
    ..In syngeneic human breast-derived cell lines, one diploid and non-transformed, the other derived from a ductal carcinoma, the loss of H3 phosphorylation is significantly more sensitive to cAMP concentration in the transformed cell line...