E Ziv

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Early therapy for latent tuberculosis infection
    E Ziv
    Department of Medicine, Veterans Affairs Medical Center, San Francisco 94121, USA
    Am J Epidemiol 153:381-5. 2001
  2. ncbi Mammographic density and estrogen receptor status of breast cancer
    Elad Ziv
    Department of Medicine, University of California at San Francisco, 1635 Divisadero Street, Suite 600, San Francisco, CA 04115, USA
    Cancer Epidemiol Biomarkers Prev 13:2090-5. 2004
  3. ncbi Human population structure and genetic association studies
    Elad Ziv
    Division of General Internal Medicine and Division of Pulmonary Medicine, Department of Medicine, University of California, San Francisco, CA 94115, USA
    Pharmacogenomics 4:431-41. 2003
  4. ncbi Mammographic breast density and family history of breast cancer
    Elad Ziv
    Division of General Internal Medicine and Department of Medicine, University of California, San Francisco, USA
    J Natl Cancer Inst 95:556-8. 2003
  5. ncbi No association between the TGF-beta 1 Leu10Pro polymorphism and osteoporosis among white women in the United States
    Elad Ziv
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Am J Med 114:227-31. 2003
  6. ncbi Association between the T29-->C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The Study of Osteoporotic Fractures
    E Ziv
    Division of General Internal Medicine, Veterans Affairs Medical Center, Box 111 A1, 4150 Clement St, San Francisco, CA 94122, USA
    JAMA 285:2859-63. 2001
  7. pmc Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma
    Harriet Corvol
    Department of Biopharmaceutical Sciences, University of California, San Francisco, California, USA
    Pharmacogenet Genomics 19:489-96. 2009
  8. ncbi Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma
    Shweta Choudhry
    University of California San Francisco, San Francisco, CA 94143 0833, USA
    Am J Respir Crit Care Med 171:563-70. 2005
  9. ncbi Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics
    Keyan Salari
    Department of Medicine, University of California, San Francisco, California 94143 1732, USA
    Genet Epidemiol 29:76-86. 2005
  10. pmc European ancestry is positively associated with breast cancer risk in Mexican women
    Laura Fejerman
    Division of General Internal Medicine, Department of Medicine, Institute for Human Genetics, University of California, San Francisco, California, USA
    Cancer Epidemiol Biomarkers Prev 19:1074-82. 2010

Detail Information

Publications50

  1. ncbi Early therapy for latent tuberculosis infection
    E Ziv
    Department of Medicine, Veterans Affairs Medical Center, San Francisco 94121, USA
    Am J Epidemiol 153:381-5. 2001
    ..Analysis of the model suggests that programs such as contact investigations, which identify and treat persons recently infected with Mycobacterium tuberculosis, may have a substantial effect on controlling tuberculosis epidemics...
  2. ncbi Mammographic density and estrogen receptor status of breast cancer
    Elad Ziv
    Department of Medicine, University of California at San Francisco, 1635 Divisadero Street, Suite 600, San Francisco, CA 04115, USA
    Cancer Epidemiol Biomarkers Prev 13:2090-5. 2004
    ..We determined if mammographic density is associated more strongly with ER-positive breast cancer than with ER-negative breast cancer...
  3. ncbi Human population structure and genetic association studies
    Elad Ziv
    Division of General Internal Medicine and Division of Pulmonary Medicine, Department of Medicine, University of California, San Francisco, CA 94115, USA
    Pharmacogenomics 4:431-41. 2003
    ..Unlinked genetic markers may be used to detect confounding in association studies. In addition, the information from unlinked markers may be used to adjust genetic associations...
  4. ncbi Mammographic breast density and family history of breast cancer
    Elad Ziv
    Division of General Internal Medicine and Department of Medicine, University of California, San Francisco, USA
    J Natl Cancer Inst 95:556-8. 2003
    ..37, 95% confidence interval [CI] = 0.96 to 1.89; BI-RADS 3, OR = 1.70, 95% CI = 1.19 to 2.40; BI-RADS 4, OR = 1.70, 95% CI = 1.05 to 2.71). Thus, the genetic factors that determine breast density may determine breast cancer risk...
  5. ncbi No association between the TGF-beta 1 Leu10Pro polymorphism and osteoporosis among white women in the United States
    Elad Ziv
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Am J Med 114:227-31. 2003
  6. ncbi Association between the T29-->C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The Study of Osteoporotic Fractures
    E Ziv
    Division of General Internal Medicine, Veterans Affairs Medical Center, Box 111 A1, 4150 Clement St, San Francisco, CA 94122, USA
    JAMA 285:2859-63. 2001
    ..A T-->C (thymine to cytosine) transition in the 29th nucleotide in the coding sequence results in a leucine to proline substitution at the 10th amino acid and is associated with increased serum levels of TGF-beta1...
  7. pmc Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma
    Harriet Corvol
    Department of Biopharmaceutical Sciences, University of California, San Francisco, California, USA
    Pharmacogenet Genomics 19:489-96. 2009
    ..Therefore, we reasoned that interactions between the IL6 and IL6R genes might be associated with bronchodilator drug responsiveness to albuterol in asthmatic patients...
  8. ncbi Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma
    Shweta Choudhry
    University of California San Francisco, San Francisco, CA 94143 0833, USA
    Am J Respir Crit Care Med 171:563-70. 2005
    ..We tested the association of beta(2)AR genotypes with asthma severity and bronchodilator response to albuterol in Puerto Ricans and Mexicans with asthma...
  9. ncbi Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics
    Keyan Salari
    Department of Medicine, University of California, San Francisco, California 94143 1732, USA
    Genet Epidemiol 29:76-86. 2005
    ..These results suggest that asthma severity may be influenced by genetic factors differentiating Europeans and Native Americans in Mexican Americans, although differing results for Puerto Ricans require further investigation...
  10. pmc European ancestry is positively associated with breast cancer risk in Mexican women
    Laura Fejerman
    Division of General Internal Medicine, Department of Medicine, Institute for Human Genetics, University of California, San Francisco, California, USA
    Cancer Epidemiol Biomarkers Prev 19:1074-82. 2010
    ....
  11. ncbi CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma
    Shweta Choudhry
    University of California San Francisco, DNA Bank Lung Biology Center, San Francisco General Hospital, Bldg 30, 5th Floor, Room 3501H, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Am J Respir Crit Care Med 172:173-82. 2005
    ..A recent family-based genomewide screen revealed linkage between the 5q31 region and the diagnosis of asthma, but only in those exposed to environmental tobacco smoke (ETS). Among the candidate genes in this region is CD14...
  12. ncbi ADAM33 is not associated with asthma in Puerto Rican or Mexican populations
    Denise L Lind
    University of California at San Francisco, San Francisco, CA 94143 0833, USA
    Am J Respir Crit Care Med 168:1312-6. 2003
    ..We conclude that the ADAM33 gene is not an important risk factor for asthma or for asthma-associated phenotypes in Mexicans or in Puerto Ricans...
  13. ncbi Population stratification confounds genetic association studies among Latinos
    Shweta Choudhry
    University of California, San Francisco, 94143 0833, USA
    Hum Genet 118:652-64. 2006
    ..Our findings suggest that empirical assessment of the effects of stratification is critical to appropriately interpret the results of case-control studies in admixed populations...
  14. ncbi African ancestry, socioeconomic status, and kidney function in elderly African Americans: a genetic admixture analysis
    Carmen A Peralta
    Department of Medicine, University of California at San Francisco, San Francisco, California 94124, USA
    J Am Soc Nephrol 17:3491-6. 2006
    ..Rather, kidney dysfunction in elderly African Americans seems more attributable to differences in environmental and social factors...
  15. ncbi Genetic admixture, adipocytokines, and adiposity in Black Americans: the Health, Aging, and Body Composition study
    Christina L Wassel Fyr
    Department of Epidemiology, University of Minnesota, Minneapolis, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Hum Genet 121:615-24. 2007
    ..The association with adiponectin became stronger after adjustment for adiposity. These novel findings suggest that admixture mapping may identify genetic factors influencing the levels of IL-6 SR, CRP, IL-2 SR, and adiponectin...
  16. pmc Dissecting complex diseases in complex populations: asthma in latino americans
    Shweta Choudhry
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 2911, USA
    Proc Am Thorac Soc 4:226-33. 2007
    ....
  17. ncbi Methylenetetrahydrofolate reductase C677T polymorphism and cognitive function in older women
    Jacob S Elkins
    Department of Neurology, School of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    Am J Epidemiol 166:672-8. 2007
    ..035). Although the strength of the observed associations was modest, these results lend some support to the theory that an elevated homocysteine level contributes to cognitive decline...
  18. doi Population differences in breast cancer severity
    Laura Fejerman
    Division of General Internal Medicine, Department of Medicine, Institute for Human Genetics and Helen Diller Family Comprehensive Cancer Center at UCSF, 2200 Post Street, San Francisco, CA 94143 1732, USA
    Pharmacogenomics 9:323-33. 2008
    ..Studies evaluating the risk for particular tumor subtypes combining genetic and environmental variables and analyzing cases from different populations are needed to understand population differences in the severity of breast cancer...
  19. pmc Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region
    Shweta Choudhry
    Institute for Human Genetics, University of California, San Francisco, CA, USA
    Hum Genet 123:455-68. 2008
    ..3 region. Our results provide strong evidence that the previously linked 5q23 region is associated with asthma in Puerto Ricans. The detection of causative variants in this region will require fine mapping and functional validation...
  20. pmc Genetic ancestry and risk of breast cancer among U.S. Latinas
    Laura Fejerman
    Division of General Internal Medicine and Lung Biology Center, Department of Medicine, University of California, San Francisco, CA 94143 1732, USA
    Cancer Res 68:9723-8. 2008
    ..39; 95% CI, 1.06-2.11; P=0.013). Further work is needed to determine if the association is due to genetic differences between populations or possibly due to environmental factors not measured...
  21. ncbi Genetic ancestry and risk factors for breast cancer among Latinas in the San Francisco Bay Area
    Elad Ziv
    Division of General Internal Medicine, University of California San Francisco, Box 1732, San Francisco, CA 94143, USA
    Cancer Epidemiol Biomarkers Prev 15:1878-85. 2006
    ..We reasoned that if genetic ancestry is associated with known breast cancer risk factors, then the results of genetic association studies would be confounded...
  22. pmc An admixture scan in 1,484 African American women with breast cancer
    Laura Fejerman
    Division of General Internal Medicine, Department of Medicine, Institute for Human Genetics and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA
    Cancer Epidemiol Biomarkers Prev 18:3110-7. 2009
    ..However, we found little evidence that genetic ancestry at any one region contributes significantly to breast cancer risk or hormone receptor status...
  23. pmc Ancestry-related assortative mating in Latino populations
    Neil Risch
    Institute for Human Genetics, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
    Genome Biol 10:R132. 2009
    ..While spouse correlations have been documented for numerous traits, no prior studies have assessed assortative mating for genetic ancestry in admixed populations...
  24. pmc The Association of African Ancestry and elevated creatinine in the Coronary Artery Risk Development in Young Adults (CARDIA) Study
    Carmen A Peralta
    Department of Medicine, University of California San Francisco, USA
    Am J Nephrol 31:202-8. 2010
    ..05 (4.81-17.02) for black men with >80% African ancestry. Genetic factors common to African ancestry may be associated with increased risk of early kidney dysfunction in a young, healthy population, particularly among black men...
  25. doi Confounding in genetic association studies and its solutions
    Donglei Hu
    Institute for Human Genetics, Comprehensive Cancer Center, Department of Medicine, University of California San Francisco, San Francisco, California, USA
    Methods Mol Biol 448:31-9. 2008
    ..Confounding can be detected and adjusted. Major methods that adjust for population stratification are described and explained in this chapter. Their advantages and disadvantages are discussed...
  26. ncbi The importance of race and ethnic background in biomedical research and clinical practice
    Esteban Gonzalez Burchard
    Lung Biology Center, University of California, San Francisco, CA 94143 0833, USA
    N Engl J Med 348:1170-5. 2003
  27. pmc Ancestry-environment interactions and asthma risk among Puerto Ricans
    Shweta Choudhry
    University of California, San Francisco, San Francisco, CA 94143 2911, USA
    Am J Respir Crit Care Med 174:1088-93. 2006
    ..We hypothesized that, in this admixed population, the association between SES and asthma may interact with genetic ancestry...
  28. ncbi Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations
    Hui Ju Tsai
    Department of Medicine, University of California, Box 0833, San Francisco, CA, 94143 0833, USA
    Hum Genet 118:424-33. 2005
    ..These simulations are meant to provide some practical guidelines for investigators conducting association studies in admixed populations...
  29. ncbi Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma
    Esteban Gonzalez Burchard
    University of California, San Francisco, 94143 0833, USA
    Am J Respir Crit Care Med 169:386-92. 2004
    ..We conclude that Puerto Ricans with asthma respond less to albuterol than do Mexicans with asthma. These findings underscore the need for additional research on racial/ethnic differences in asthma morbidity and response to therapy...
  30. pmc Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research
    Esteban Gonzalez Burchard
    Department of Medicine, University of California, San Francisco, CA 94143 0833, USA
    Am J Public Health 95:2161-8. 2005
    ....
  31. ncbi Mammographic breast density and the Gail model for breast cancer risk prediction in a screening population
    Jeffrey A Tice
    Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA 94143 1732, USA
    Breast Cancer Res Treat 94:115-22. 2005
    ..Although the current standard, the Gail model, is well calibrated in populations, it performs poorly for individuals. Mammographic breast density (BD) may improve the predictive accuracy of the Gail model...
  32. pmc Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations
    Hui Ju Tsai
    Department of Medicine, Study of African American, Asthma, Genes and Environments, SAGE, University of California, 0833, San Francisco, 94143 0833, USA
    Hum Genet 118:626-39. 2006
    ..Our present work demonstrates that admixture-matched case-control strategies can efficiently control population stratification confounding in admixed populations...
  33. ncbi Are breast density and bone mineral density independent risk factors for breast cancer?
    Karla Kerlikowske
    Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA
    J Natl Cancer Inst 97:368-74. 2005
    ..We determined whether mammographic breast density and BMD of the hip and spine are correlated and independently associated with breast cancer risk...
  34. pmc Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity
    Ludmila Pawlikowska
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, USA
    Aging Cell 8:460-72. 2009
    ..35, 95%CI = 1.15-1.57, adjusted P = 0.0093). These results demonstrate that common variants in several genes in the insulin/IGF1 pathway are associated with human lifespan...
  35. pmc Serum insulin-like growth factor-1 binding proteins 1 and 2 and mortality in older adults: the Health, Aging, and Body Composition Study
    Donglei Hu
    Department of Medicine, University of California at San Francisco, San Francisco, California, USA
    J Am Geriatr Soc 57:1213-8. 2009
    ..To evaluate the relationship between serum insulin-like growth factor 1 (IGF-1), IGF-1 binding protein 1 (IGFBP-1), and IGF-1 binding protein 2 (IGFBP-2) and fasting insulin, fasting glucose, adiposity, and mortality in older adults...
  36. pmc Recent advances of genetic ancestry testing in biomedical research and direct to consumer testing
    M Via
    Institute for Human Genetics, University of California, San Francisco, CA 94143 2911, USA
    Clin Genet 76:225-35. 2009
    ....
  37. pmc Potential public health impact of new tuberculosis vaccines
    Elad Ziv
    University of California San Francisco, San Francisco, California, USA
    Emerg Infect Dis 10:1529-35. 2004
    ..Even widely deployed and highly effective (50%-90% efficacy) pre- or postexposure vaccines would only be able to reduce the number of TB cases by one third. We discuss the health policy implications of our analyses...
  38. ncbi The genetics of human longevity
    Warren S Browner
    California Pacific Medical Center Research Institute, San Francisco, California 94115, USA
    Am J Med 117:851-60. 2004
    ..Despite the challenges in study design and analysis that face investigators in this area, the identification of genetic pathways that regulate longevity may suggest potential targets for therapy...
  39. ncbi Estrogen metabolizing polymorphisms and breast cancer risk among older white women
    Francesmary Modugno
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA, USA
    Breast Cancer Res Treat 93:261-70. 2005
    ..To investigate breast cancer risk according to metabolizing genes polymorphisms in older women...
  40. ncbi Estrogen receptor alpha haplotypes and breast cancer risk in older Caucasian women
    Jun Wang
    Human Genetics Department, Roche Molecular Systems, Inc, 1145 Atlantic Ave, Alameda, CA 94555, USA
    Breast Cancer Res Treat 106:273-80. 2007
    ..001% in cases and controls). No other statistically significant associations were observed between ESR1 haplotypes from the same four SNPs and the risk of breast cancer in older Caucasian women...
  41. pmc Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study
    Alexander P Reiner
    Department of Epidemiology, University of Washington, Seattle, WA 98101 1448, USA
    Am J Hum Genet 76:463-77. 2005
    ..Complementary methods that identify discrete subgroups on the basis of genetic similarity may help to further characterize the complex biodemographic structure of human populations...
  42. ncbi Genetic ancestry, population sub-structure, and cardiovascular disease-related traits among African-American participants in the CARDIA Study
    Alexander P Reiner
    Department of Epidemiology, University of Washington, Box 357236, Seattle, WA 98195, USA
    Hum Genet 121:565-75. 2007
    ..These results demonstrate the potential for confounding of genetic associations with some cardiovascular disease-related traits in large studies involving US African-Americans...
  43. pmc Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels
    David Reich
    Department of Genetics, Harvard Medical School, New Research Building, Boston, MA 02115, USA
    Am J Hum Genet 80:716-26. 2007
    ..0x10-12 for IL-6 SR, and P<2.0x10-9 for IL-6. These results also serve as an important proof of principle, showing that admixture mapping can not only coarsely localize but can also fine map a phenotypically important variant...
  44. pmc Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study
    Lucia A Hindorff
    Department of Epidemiology, University of Washington, Seattle, WA, United States
    Atherosclerosis 197:922-30. 2008
    ..If confirmed, CRP genetic variants may be weakly associated with CV and non-CV mortality in older adults, particularly in self-identified blacks...
  45. ncbi Association of estrogen receptor alpha polymorphisms with breast cancer risk in older Caucasian women
    Francesmary Modugno
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Int J Cancer 116:984-91. 2005
    ..60 vs. 1.12 for nulliparous vs. parous women; interaction p = 0.03). ESR1 polymorphisms in combination with lifestyle factors may be associated with breast cancer risk in older Caucasian women...
  46. pmc Tracing sub-structure in the European American population with PCA-informative markers
    Peristera Paschou
    Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupoli, Greece
    PLoS Genet 4:e1000114. 2008
    ..Furthermore, our redundancy removal algorithm can be applied on sets of ancestry informative markers selected with any method in order to select the most uncorrelated SNPs, and significantly decreases genotyping costs...
  47. pmc Comparing genetic ancestry and self-described race in african americans born in the United States and in Africa
    Rona Yaeger
    Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, USA
    Cancer Epidemiol Biomarkers Prev 17:1329-38. 2008
    ..Genetic classifications of ancestry may provide a more objective and accurate method of defining homogenous populations for the investigation of specific population-disease associations...
  48. pmc PCA-correlated SNPs for structure identification in worldwide human populations
    Peristera Paschou
    Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupoli, Greece
    PLoS Genet 3:1672-86. 2007
    ....
  49. pmc Admixture mapping of white cell count: genetic locus responsible for lower white blood cell count in the Health ABC and Jackson Heart studies
    Michael A Nalls
    Laboratory of Epidemiology, Demography and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892, USA
    Am J Hum Genet 82:81-7. 2008
    ..Additional studies are needed to determine the biological mechanism for this effect and its clinical implications...
  50. pmc Categorization of humans in biomedical research: genes, race and disease
    Neil Risch
    Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305 5120, USA
    Genome Biol 3:comment2007. 2002
    ..An epidemiologic perspective on the issue of human categorization in biomedical and genetic research strongly supports the continued use of self-identified race and ethnicity...