Detail Information
Publications
Adenosine-to-inosine RNA editingBoris Zinshteyn
The Wistar Institute, Gene Expression and Regulation, Philadelphia, PA 19104, USA
Wiley Interdiscip Rev Syst Biol Med 1:202-9. 2009..The vast majority of editing sites are in noncoding sequences. This includes microRNAs, as well as the introns and 3' untranslated regions of messenger RNAs, which play important roles in the RNA-mediated regulation of gene expression...
Redirection of silencing targets by adenosine-to-inosine editing of miRNAsYukio Kawahara
Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA
Science 315:1137-40. 2007....
RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complexYukio Kawahara
The Wistar Institute, 3601 Spruce Street, Philadelphia, Pennsylvania 19104, USA
EMBO Rep 8:763-9. 2007..Our results indicate that A --> I conversion at two specific positions of the pre-miRNA foldback structure can affect its interaction with the Dicer-TRBP complex, showing a new regulatory role of A --> I RNA editing in miRNA biogenesis...
