Research Topics
| B J ZinkSummaryAffiliation: University of Michigan Country: USA Publications
| Collaborators
|
Detail Information
Publications
Effects of ethanol in an experimental model of combined traumatic brain injury and hemorrhagic shockB J Zink
Department of Surgery, University of Michigan, Ann Arbor, USA
Acad Emerg Med 5:9-17. 1998..Given that clinical and laboratory studies suggest that ethanol and hemorrhagic shock (HS) potentiate traumatic brain injury (TBI), the authors studied the effects of ethanol in a model of combined TBI and HS...
Creator and keeper of the flame of emergency medicine: John G. Wiegenstein, MD, 1930-2004Brian J Zink
Department of Emergency Medicine, University of Michigan Medical School, Ann Arbor, MI 48109-0303, USA
Ann Emerg Med 45:241-3. 2005
Out-of-hospital endotracheal intubation in traumatic brain injury: outcomes research provides us with an unexpected outcomeBrian J Zink
Department of Emergency Medicine, University of Michigan, Ann Arbor, MI 48109-0303, USA
Ann Emerg Med 44:451-3. 2004
Effects of ethanol and naltrexone in a model of traumatic brain injury with hemorrhagic shockB J Zink
University of Michigan Emergency Medicine Research Laboratory and Crosby Neurosurgical Laboratory Ann Arbor, Michigan 48109 0303, USA
Alcohol Clin Exp Res 25:916-23. 2001..Endogenous opioids may play a role in ethanol intoxication and TBI. We studied the effects of ethanol and the opiate antagonist agent naltrexone (NTX) in a TBI/HS model...
Traumatic brain injury outcome: concepts for emergency careB J Zink
Department of Emergency Medicine, University of Michigan, Ann Arbor, MI 48109 0303, USA
Ann Emerg Med 37:318-32. 2001..This review addresses new concepts and information in the pathophysiology of TBI and secondary brain injury and demonstrates how emergency management may be linked to neurologic outcome...
Effects of ethanol on brain lactate in experimental traumatic brain injury with hemorrhagic shockB J Zink
University of Michigan, Section of Emergency Medicine and the Emergency Medicine Research Laboratory, Ann Arbor, MI 48109 0303, USA
Brain Res 837:1-7. 1999..This study investigated the effects of ethanol (ET) on brain lactate concentrations and acidosis in a TBI/HS model...
Acute ethanol intoxication in a model of traumatic brain injury with hemorrhagic shock: effects on early physiological responseB J Zink
Department of Surgery, University of Michigan, Ann Arbor, USA
J Neurosurg 89:983-90. 1998..Because previous studies have shown a potentiating effect of ethanol (EtOH) on TBI and hemorrhagic shock (HS), the authors investigated the effects of EtOH on the early physiological response to TBI with and without HS...
Effect of initially limited resuscitation in a combined model of fluid-percussion brain injury and severe uncontrolled hemorrhagic shockS A Stern
Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor 48109 0303, USA
J Neurosurg 93:305-14. 2000..In this study the authors evaluated the effects of limited resuscitation on outcome in combined fluid-percussion injury (FPI) and uncontrolled hemorrhage...
Academic radiology and the emergency department: does it need changing?Caroline E Blane
Department of Radiology, The University of Michigan Health System, East Medical Drive, Ann Arbor, MI 48109 0030, USA
Acad Radiol 14:625-30. 2007..We hypothesized the resident preliminary reports were better than generalist radiology interpretations, although inferior to subspecialty interpretations...
Learning from our historyBrian J Zink
Department of Emergency Medicine, The Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA
J Emerg Med 35:1-3. 2008
The role of the choroid plexus in neutrophil invasion after traumatic brain injuryJoanna Szmydynger-Chodobska
Department of Emergency Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
J Cereb Blood Flow Metab 29:1503-16. 2009..This is the first detailed analysis of the BCSFB function related to neutrophil trafficking. Our observations support the role of this barrier in posttraumatic neutrophil invasion...
Pathophysiology of traumatic brain injuryMark W Greve
Department of Emergency Medicine, Warren Alpert School of Medicine, Brown University, Providence, RI, USA
Mt Sinai J Med 76:97-104. 2009..The best hope for improving outcome in traumatic brain injury patients is a better understanding of these processes and the development of therapies that can limit secondary brain injury...
Effects of cocaine in an experimental model of traumatic brain injuryBrian D McBeth
University of Michigan, Ann Arbor, MI, USA
Acad Emerg Med 12:483-90. 2005..Cocaine intoxication is found in a significant subset of emergency department (ED) patients presenting with traumatic brain injury (TBI)...
Guidelines for the management of severe head injury: are emergency physicians following them?James E Huizenga
Department of Emergency Medicine, Wright State University, Dayton, OH, USA
Acad Emerg Med 9:806-12. 2002..These evidence-based clinical guidelines (CGs) recommended against prophylactic hyperventilation and glucocorticoid use and advocated for aggressive blood pressure (BP) resuscitation, and the careful use of mannitol...
The effects of alcohol on head injury in the motor vehicle crash victimRebecca M Cunningham
University of Michigan Medical Center, Department of Emergency Medicine, TC B134 1500 East Medical Center Drive, Ann Arbor 48109-0303, USA
Alcohol Alcohol 37:236-40. 2002..We suggest that alcohol potentiates severity of TBI as determined from head CT among MVC victims. Further research will be needed to substantiate this finding as well as to determine its long-term effect on clinical outcome...
Vasopressin amplifies the production of proinflammatory mediators in traumatic brain injuryJoanna Szmydynger-Chodobska
Department of Emergency Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
J Neurotrauma 27:1449-61. 2010..These data demonstrate that AVP plays an important role in exacerbating the brain inflammatory response to injury...
