Xiangdong Zhu

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Oblique-incidence reflectivity difference microscope for label-free high-throughput detection of biochemical reactions in a microarray format
    Xiangdong Zhu
    Department of Physics, University of California, CA 95616, USA
    Appl Opt 46:1890-5. 2007
  2. pmc Discovering small molecule ligands of vascular endothelial growth factor that block VEGF-KDR binding using label-free microarray-based assays
    James P Landry
    Department of Physics, University of California at Davis, Davis, CA 95616, USA
    Assay Drug Dev Technol 11:326-32. 2013
  3. pmc Fluorescent labeling agents change binding profiles of glycan-binding proteins
    Yiyan Fei
    Department of Physics, University of California at Davis, California 95616, USA
    Mol Biosyst 7:3343-52. 2011
  4. pmc Simultaneous measurement of 10,000 protein-ligand affinity constants using microarray-based kinetic constant assays
    James P Landry
    Department of Physics, University of California at Davis, Davis, CA 95616, USA
    Assay Drug Dev Technol 10:250-9. 2012
  5. pmc Screening small-molecule compound microarrays for protein ligands without fluorescence labeling with a high-throughput scanning microscope
    Yiyan Fei
    University of California at Davis, Department of Physics, Davis, California 95616, USA
    J Biomed Opt 15:016018. 2010

Collaborators

  • Xi Chen
  • Yanhong Li
  • James P Landry
  • Yiyan Fei
  • Pierre Lee
  • Guoliang Yu
  • Yaohuang Ke
  • Hai Yu
  • Yung Shin Sun
  • Kam Lau
  • Harshal A Chokhawala
  • Shengshu Huang
  • Kit S Lam
  • Chun Yi Wu
  • Xiaobing Wang
  • Yungshin Sun
  • Juntao Luo

Detail Information

Publications5

  1. pmc Oblique-incidence reflectivity difference microscope for label-free high-throughput detection of biochemical reactions in a microarray format
    Xiangdong Zhu
    Department of Physics, University of California, CA 95616, USA
    Appl Opt 46:1890-5. 2007
    ..x 3 in. (2.54 cm x 7.62 cm) microscope slide...
  2. pmc Discovering small molecule ligands of vascular endothelial growth factor that block VEGF-KDR binding using label-free microarray-based assays
    James P Landry
    Department of Physics, University of California at Davis, Davis, CA 95616, USA
    Assay Drug Dev Technol 11:326-32. 2013
    ..3 to 60 μM. The inhibitory potency of these inhibitors found in the microarray-based assay was confirmed by their inhibition of VEGF-induced VEGFR2 phosphorylation in a cell-based assay...
  3. pmc Fluorescent labeling agents change binding profiles of glycan-binding proteins
    Yiyan Fei
    Department of Physics, University of California at Davis, California 95616, USA
    Mol Biosyst 7:3343-52. 2011
    ..This study highlights the importance of label-free real-time detection of protein-ligand interactions and the potential pitfall in interpreting fluorescence-based assays for characterization of protein-glycan interactions...
  4. pmc Simultaneous measurement of 10,000 protein-ligand affinity constants using microarray-based kinetic constant assays
    James P Landry
    Department of Physics, University of California at Davis, Davis, CA 95616, USA
    Assay Drug Dev Technol 10:250-9. 2012
    ....
  5. pmc Screening small-molecule compound microarrays for protein ligands without fluorescence labeling with a high-throughput scanning microscope
    Yiyan Fei
    University of California at Davis, Department of Physics, Davis, California 95616, USA
    J Biomed Opt 15:016018. 2010
    ....

Research Grants1