Research Topics
| Changfang ZhuSummaryAffiliation: University of Wisconsin Country: USA Publications
| Collaborators
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Detail Information
Publications
Diagnosis of breast cancer using fluorescence and diffuse reflectance spectroscopy: a Monte-Carlo-model-based approachChangfang Zhu
University of Wisconsin Madison, Department of Electrical and Computer Engineering, Madison, Wisconsin 53705, USA
J Biomed Opt 13:034015. 2008....
Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulationChangfang Zhu
University of Wisconsin-Madison, Department of Electrical and Computer Engineering, Madison, Wisconsin 53706, USA
J Biomed Opt 8:237-47. 2003..The simulation results are used to design a simple fiber optic probe that combines both the VA and MD geometries to enable fluorescence measurements from the different sublayers within human epithelial tissues...
Autofluorescence and diffuse reflectance properties of malignant and benign breast tissuesTara M Breslin
Department of Surgery, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
Ann Surg Oncol 11:65-70. 2004..We hypothesized that a statistically significant difference would be demonstrated between benign and malignant breast tissues on the basis of their unique fluorescence and reflectance properties...
Use of a multiseparation fiber optic probe for the optical diagnosis of breast cancerChangfang Zhu
University of Wisconsin-Madison, Department of Electrical and Computer Engineering, Madison, Wisconsin 53706, USA
J Biomed Opt 10:024032. 2005....
Fluorescence spectroscopy: an adjunct diagnostic tool to image-guided core needle biopsy of the breastChangfang Zhu
Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53706, USA
IEEE Trans Biomed Eng 56:2518-28. 2009..This study demonstrates the feasibility of performing fluorescence spectroscopy during clinical core needle breast biopsy, and the potential of this technique for identifying breast malignancy in vivo...
Model based and empirical spectral analysis for the diagnosis of breast cancerChangfang Zhu
Department of Electrical and Computer Engineering, University of Wisconsin Madison, WI 53705, USA
Opt Express 16:14961-78. 2008....
Investigation of fiber-optic probe designs for optical spectroscopic diagnosis of epithelial pre-cancersMelissa C Skala
Department of Biomedical Engineering, University of Wisconsin, 1550 Engineering Drive, Madison, WI 53706, USA
Lasers Surg Med 34:25-38. 2004....
Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction techniqueChangfang Zhu
Department of Electrical and Computer Engineering, University of Wisconsin, Madison, Wisconsin 53705, USA
Lasers Surg Med 38:714-24. 2006..While both methods yielded similar classification accuracies, the model based approach provided insight into the physiological and structural features that discriminate between malignant and non-malignant breast tissues...
Electromagnetic spectroscopy of normal breast tissue specimens obtained from reduction surgeries: comparison of optical and microwave propertiesMariya Lazebnik
Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53706, USA
IEEE Trans Biomed Eng 55:2444-51. 2008..55, p<0.01). Our results suggest that combining optical and microwave modalities for analyzing breast tissue samples may serve as a crosscheck and provide complementary information about tissue composition...
Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003)Gregory M Palmer
Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA
IEEE Trans Biomed Eng 50:1233-42. 2003..The fluorescence excitation-emission wavelengths identified as being diagnostic from the PCA-SVM algorithm suggest that the important fluorophores for breast cancer diagnosis are most likely tryptophan, NAD(P)H and flavoproteins...
Experimental validation of Monte Carlo modeling of fluorescence in tissues in the UV-visible spectrumQuan Liu
University of Wisconsin-Madison, Department of Biomedical Engineering, Madison, Wisconsin 53706, USA
J Biomed Opt 8:223-36. 2003..The fiber optic probe geometries that are modeled in this study include those commonly used for measuring fluorescence from tissues in practice...
Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosisGregory M Palmer
Department of Biomedical Engineering, 136 Hudson Hall, Box 90281, Duke University, Durham, North Carolina 27708-0281, USA
Appl Opt 45:1072-8. 2006....
