Xin Joseph Zhou

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. doi request reprint The aging kidney
    Xin J Zhou
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Kidney Int 74:710-20. 2008
  2. ncbi request reprint Association of renal injury with increased oxygen free radical activity and altered nitric oxide metabolism in chronic experimental hemosiderosis
    X J Zhou
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75390 9073, USA
    Lab Invest 80:1905-14. 2000
  3. ncbi request reprint Defective calcium signalling in uraemic platelets and its amelioration with long-term erythropoietin therapy
    Xin J Zhou
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9073, USA
    Nephrol Dial Transplant 17:992-7. 2002
  4. ncbi request reprint Association of renal injury with nitric oxide deficiency in aged SHR: prevention by hypertension control with AT1 blockade
    Xin Joseph Zhou
    Department of Pathology, Division of Renal Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9073, USA
    Kidney Int 62:914-21. 2002
  5. doi request reprint Renal senescence in 2008: progress and challenges
    Xin J Zhou
    Department of Pathology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9073, USA
    Int Urol Nephrol 40:823-39. 2008
  6. ncbi request reprint Sle3 and Sle5 can independently couple with Sle1 to mediate severe lupus nephritis
    K Liu
    Department of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9093, USA
    Genes Immun 8:634-45. 2007
  7. pmc The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis
    Q Z Li
    Department of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Genes Immun 10:503-8. 2009
  8. ncbi request reprint Down-regulation of renal endothelial nitric oxide synthase expression in experimental glomerular thrombotic microangiopathy
    X J Zhou
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235 9073, USA
    Lab Invest 80:1079-87. 2000
  9. ncbi request reprint Docosahexaenoic acid ameliorates murine ischemic acute renal failure and prevents increases in mRNA abundance for both TNF-alpha and inducible nitric oxide synthase
    Mariusz L Kielar
    Department of Internal Medicine, Division of Nephrology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Am Soc Nephrol 14:389-96. 2003

Detail Information

Publications9

  1. doi request reprint The aging kidney
    Xin J Zhou
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Kidney Int 74:710-20. 2008
    ..This review summarizes the structural and functional changes of the aging kidney and highlights the advances made in our understanding of the renal aging process...
  2. ncbi request reprint Association of renal injury with increased oxygen free radical activity and altered nitric oxide metabolism in chronic experimental hemosiderosis
    X J Zhou
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75390 9073, USA
    Lab Invest 80:1905-14. 2000
    ..These findings point to the possible role of ROS in chronic iron overload-induced renal injury...
  3. ncbi request reprint Defective calcium signalling in uraemic platelets and its amelioration with long-term erythropoietin therapy
    Xin J Zhou
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9073, USA
    Nephrol Dial Transplant 17:992-7. 2002
    ..The present study examined the hypothesis that the improved uraemic platelet function after Epo therapy is, in part, due to correction of the platelet calcium signalling...
  4. ncbi request reprint Association of renal injury with nitric oxide deficiency in aged SHR: prevention by hypertension control with AT1 blockade
    Xin Joseph Zhou
    Department of Pathology, Division of Renal Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9073, USA
    Kidney Int 62:914-21. 2002
    ..The relationship between renal NO system, Ang II activity and renal injury in aged SHR is not fully understood...
  5. doi request reprint Renal senescence in 2008: progress and challenges
    Xin J Zhou
    Department of Pathology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9073, USA
    Int Urol Nephrol 40:823-39. 2008
    ..A better understanding of these mechanisms may help to preserve renal function, improve morbidity and mortality, and hopefully reduce healthcare costs for the aging population...
  6. ncbi request reprint Sle3 and Sle5 can independently couple with Sle1 to mediate severe lupus nephritis
    K Liu
    Department of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9093, USA
    Genes Immun 8:634-45. 2007
    ..Our results indicate that Sle3 and Sle5 can independently complement with Sle1, through shared and unique mechanisms, to mediate the development of severe autoimmunity...
  7. pmc The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis
    Q Z Li
    Department of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Genes Immun 10:503-8. 2009
    ..Sle3 congenics. Taken together with earlier studies, these findings indicate that kallikreins play an important protective role in autoantibody-initiated GN and could constitute potential candidate genes for anti-GBM-induced GN and SLN...
  8. ncbi request reprint Down-regulation of renal endothelial nitric oxide synthase expression in experimental glomerular thrombotic microangiopathy
    X J Zhou
    Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235 9073, USA
    Lab Invest 80:1079-87. 2000
    ..The associated decline in intrarenal endothelial NO production/availability may result in renal vasoconstriction and a hypercoagulative state, which may contribute to the pathogenesis of endotoxin-induced TMA...
  9. ncbi request reprint Docosahexaenoic acid ameliorates murine ischemic acute renal failure and prevents increases in mRNA abundance for both TNF-alpha and inducible nitric oxide synthase
    Mariusz L Kielar
    Department of Internal Medicine, Division of Nephrology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Am Soc Nephrol 14:389-96. 2003
    ..In addition, the data may have therapeutic implications, because the DHA improves ARF even when administered at 4 h after reperfusion...