Affiliation: University of Alabama at Birmingham
- Inhibiting na+/k+ ATPase can impair mitochondrial energetics and induce abnormal Ca2+ cycling and automaticity in Guinea pig cardiomyocytesQince Li
Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America Comprehensive Cardiovascular Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
PLoS ONE 9:e93928. 2014..The findings suggest that targeting both ion handling and mitochondria could be a very promising strategy to develop new glycoside-based therapies in the treatment of heart failure. ..
- Cardiac mitochondrial network excitability: insights from computational analysisLufang Zhou
Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, 35294, USA
Am J Physiol Heart Circ Physiol 302:H2178-89. 2012....
- Dynamic modulation of Ca2+ sparks by mitochondrial oscillations in isolated guinea pig cardiomyocytes under oxidative stressLufang Zhou
Department of Medicine, Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
J Mol Cell Cardiol 51:632-9. 2011..The results support the hypothesis that mitochondria exert an influential role on the redox environment of the Ca(2+) handling subsystem, with mechanistic implications for the pathophysiology of cardiac disease...
- Modeling cardiac action potential shortening driven by oxidative stress-induced mitochondrial oscillations in guinea pig cardiomyocytesLufang Zhou
Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Biophys J 97:1843-52. 2009....