Yong Hui Zheng

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Newly identified host factors modulate HIV replication
    Yong Hui Zheng
    Department of Medicine, Rosalind Russell Arthritis Research Center, University of California, San Francisco, San Francisco, CA 94143, USA
    Immunol Lett 97:225-34. 2005
  2. pmc Intracellular immunity to HIV-1: newly defined retroviral battles inside infected cells
    Yong Hui Zheng
    Department of Medicine, Rosalind Russell Arthritis Research Center, University of California, San Francisco, CA 94143 0703, USA
    Retrovirology 2:25. 2005
  3. ncbi request reprint Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery
    Matthias Geyer
    Department of Medicine, University of California, San Francisco, California 94143 0703, USA
    J Biol Chem 277:28521-9. 2002
  4. pmc Nef binds p6* in GagPol during replication of human immunodeficiency virus type 1
    Luciana J Costa
    Department of Medicine, University of California San Francisco, UCSF Mt Zion Cancer Center, 2340 Sutter Street, San Francisco, CA 94115, USA
    J Virol 78:5311-23. 2004
  5. ncbi request reprint Human p32 protein relieves a post-transcriptional block to HIV replication in murine cells
    Yong Hui Zheng
    Department of Medicine, Rosalind Russell Medical Research Center, Mt Zion Research Building Room N231, 2340 Sutter Street, University of California, San Francisco, CA 94115, USA
    Nat Cell Biol 5:611-8. 2003
  6. pmc Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions
    Yong Hui Zheng
    Department of Medicine, Rosalind Russell Medical Research Center, University of California, San Francisco, CA 94143 0703, USA
    Proc Natl Acad Sci U S A 100:8460-5. 2003
  7. pmc Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication
    Yong Hui Zheng
    Departments of Medicine, Microbiology, and Immunology, University of California, San Francisco, 3rd and Parnassus Ave, San Francisco, CA 94143 0703, USA
    J Virol 78:6073-6. 2004

Detail Information

Publications7

  1. ncbi request reprint Newly identified host factors modulate HIV replication
    Yong Hui Zheng
    Department of Medicine, Rosalind Russell Arthritis Research Center, University of California, San Francisco, San Francisco, CA 94143, USA
    Immunol Lett 97:225-34. 2005
  2. pmc Intracellular immunity to HIV-1: newly defined retroviral battles inside infected cells
    Yong Hui Zheng
    Department of Medicine, Rosalind Russell Arthritis Research Center, University of California, San Francisco, CA 94143 0703, USA
    Retrovirology 2:25. 2005
    ..These processes also offer a tantalizing glimpse at basic cellular mechanisms that might restrict the movement of mobile genetic elements and protect the genome...
  3. ncbi request reprint Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery
    Matthias Geyer
    Department of Medicine, University of California, San Francisco, California 94143 0703, USA
    J Biol Chem 277:28521-9. 2002
    ..Finally, blocking the expression of V1H decreased the enhancement of virion infectivity by Nef. Thus, V1H can function as an adaptor for interactions between Nef and AP-2...
  4. pmc Nef binds p6* in GagPol during replication of human immunodeficiency virus type 1
    Luciana J Costa
    Department of Medicine, University of California San Francisco, UCSF Mt Zion Cancer Center, 2340 Sutter Street, San Francisco, CA 94115, USA
    J Virol 78:5311-23. 2004
    ..Our data demonstrate that the retention of Nef in the intermediate compartment interferes with viral replication and suggest a new role for Nef in the production of HIV-1...
  5. ncbi request reprint Human p32 protein relieves a post-transcriptional block to HIV replication in murine cells
    Yong Hui Zheng
    Department of Medicine, Rosalind Russell Medical Research Center, Mt Zion Research Building Room N231, 2340 Sutter Street, University of California, San Francisco, CA 94115, USA
    Nat Cell Biol 5:611-8. 2003
    ..A single substitution in hp32 of Gly 35 to Asp 35, which is found in mp32, abrogates this activity. Thus, hp32 overcomes an important post-transcriptional block to HIV replication in murine cells...
  6. pmc Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions
    Yong Hui Zheng
    Department of Medicine, Rosalind Russell Medical Research Center, University of California, San Francisco, CA 94143 0703, USA
    Proc Natl Acad Sci U S A 100:8460-5. 2003
    ..Thus, Nef also transports newly synthesized cholesterol to the site of viral budding. As such, it provides essential building blocks for the formation of viruses that replicate optimally in the host...
  7. pmc Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication
    Yong Hui Zheng
    Departments of Medicine, Microbiology, and Immunology, University of California, San Francisco, 3rd and Parnassus Ave, San Francisco, CA 94143 0703, USA
    J Virol 78:6073-6. 2004
    ..Thus, APOBEC family members might have evolved as a general defense mechanism of the body against retroviruses, retrotransposons, and other mobile genetic elements...