Detail Information
Publications
On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEFMeiying Zheng
Department of Molecular Physiology and Biological Physics, University of Virginia, PO Box 800736, Charlottesville, Virginia, 22908 0736, USA
BMC Struct Biol 9:36. 2009..These GEFs include p115, LARG and PDZRhoGEF (PRG)...
Structural features and chaperone activity of the NudC protein familyMeiying Zheng
Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
J Mol Biol 409:722-41. 2011..The availability of structural information will be of help in further studies on the cellular functions of the NudC family...
The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoATomasz Cierpicki
Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, 22908, USA
Protein Sci 18:2067-79. 2009..The complex is readily and rapidly dissociated in the presence of both GDP and GTP nucleotides, with no evidence of intermediate ternary complexes...
