Zhiyong Zhao

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. ncbi request reprint Nicotine-induced embryonic malformations mediated by apoptosis from increasing intracellular calcium and oxidative stress
    Zhiyong Zhao
    Department of Obstetrics and Gynecology, The Arkansas Center for Birth Defects Research and Prevention, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Birth Defects Res B Dev Reprod Toxicol 74:383-91. 2005
  2. ncbi request reprint Rho-associated kinases play a role in endocardial cell differentiation and migration
    Zhiyong Zhao
    Yale Child Health Research Center, Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Dev Biol 275:183-91. 2004
  3. ncbi request reprint Dietary vitamin and lipid therapy rescues aberrant signaling and apoptosis and prevents hyperglycemia-induced diabetic embryopathy in rats
    E Albert Reece
    Department of Obstetrics and Gynecology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Am J Obstet Gynecol 194:580-5. 2006
  4. ncbi request reprint Rho-associated kinases play an essential role in cardiac morphogenesis and cardiomyocyte proliferation
    Zhiyong Zhao
    Yale Child Health Research Center, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Dev Dyn 226:24-32. 2003
  5. ncbi request reprint Characterization of differential gene expression profiles in diabetic embryopathy using DNA microarray analysis
    E Albert Reece
    Department of Obstetrics and Gynecology, The Arkansas Center for Birth Defects Research and Prevention, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Am J Obstet Gynecol 195:1075-80. 2006
  6. ncbi request reprint Experimental mechanisms of diabetic embryopathy and strategies for developing therapeutic interventions
    Zhiyong Zhao
    Department of Obstetrics and Gynecology, The Arkansas Center for Birth Defects Research and Prevention, Little Rock, Arkansas, USA
    J Soc Gynecol Investig 12:549-57. 2005
  7. ncbi request reprint Aberrant patterns of cellular communication in diabetes-induced embryopathy in rats: II, apoptotic pathways
    E Albert Reece
    Department of Obstetrics and Gynecology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
    Am J Obstet Gynecol 192:967-72. 2005
  8. ncbi request reprint Involvement of c-Jun N-terminal kinases activation in diabetic embryopathy
    Peixin Yang
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, 655 W Baltimore Street, Baltimore, MD 21201, USA
    Biochem Biophys Res Commun 357:749-54. 2007
  9. doi request reprint Activation of oxidative stress signaling that is implicated in apoptosis with a mouse model of diabetic embryopathy
    Peixin Yang
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 198:130.e1-7. 2008
  10. doi request reprint Blockade of c-Jun N-terminal kinase activation abrogates hyperglycemia-induced yolk sac vasculopathy in vitro
    Peixin Yang
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 198:321.e1-7. 2008

Detail Information

Publications10

  1. ncbi request reprint Nicotine-induced embryonic malformations mediated by apoptosis from increasing intracellular calcium and oxidative stress
    Zhiyong Zhao
    Department of Obstetrics and Gynecology, The Arkansas Center for Birth Defects Research and Prevention, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Birth Defects Res B Dev Reprod Toxicol 74:383-91. 2005
    ..However, the role of nicotine in embryonic malformations has not been addressed, and the mechanisms by which nicotine affects embryonic development remain to be delineated...
  2. ncbi request reprint Rho-associated kinases play a role in endocardial cell differentiation and migration
    Zhiyong Zhao
    Yale Child Health Research Center, Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Dev Biol 275:183-91. 2004
    ..Collectively, these data show that ROCKs play an essential role in endothelial cell differentiation and migration during endocardial cushion development...
  3. ncbi request reprint Dietary vitamin and lipid therapy rescues aberrant signaling and apoptosis and prevents hyperglycemia-induced diabetic embryopathy in rats
    E Albert Reece
    Department of Obstetrics and Gynecology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Am J Obstet Gynecol 194:580-5. 2006
    ....
  4. ncbi request reprint Rho-associated kinases play an essential role in cardiac morphogenesis and cardiomyocyte proliferation
    Zhiyong Zhao
    Yale Child Health Research Center, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Dev Dyn 226:24-32. 2003
    ..These observations show that ROCK kinases play a role in cardiac development and that ROCK kinases regulate cardiac cell proliferation and cell cycle protein expression...
  5. ncbi request reprint Characterization of differential gene expression profiles in diabetic embryopathy using DNA microarray analysis
    E Albert Reece
    Department of Obstetrics and Gynecology, The Arkansas Center for Birth Defects Research and Prevention, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Am J Obstet Gynecol 195:1075-80. 2006
    ....
  6. ncbi request reprint Experimental mechanisms of diabetic embryopathy and strategies for developing therapeutic interventions
    Zhiyong Zhao
    Department of Obstetrics and Gynecology, The Arkansas Center for Birth Defects Research and Prevention, Little Rock, Arkansas, USA
    J Soc Gynecol Investig 12:549-57. 2005
    ..The ultimate goal is to develop multi-nutrient dietary supplements to eliminate embryonic abnormalities induced by maternal diabetes...
  7. ncbi request reprint Aberrant patterns of cellular communication in diabetes-induced embryopathy in rats: II, apoptotic pathways
    E Albert Reece
    Department of Obstetrics and Gynecology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
    Am J Obstet Gynecol 192:967-72. 2005
    ..The objective was to test the hypothesis that hyperglycemia-induced injury of yolk sac cell membranes is associated with disruption of cellular apoptotic signaling pathways...
  8. ncbi request reprint Involvement of c-Jun N-terminal kinases activation in diabetic embryopathy
    Peixin Yang
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, 655 W Baltimore Street, Baltimore, MD 21201, USA
    Biochem Biophys Res Commun 357:749-54. 2007
    ..JNK activation itself is sufficient to induce embryonic anomalies, and thus mimics the teratogenic effect of hyperglycemia...
  9. doi request reprint Activation of oxidative stress signaling that is implicated in apoptosis with a mouse model of diabetic embryopathy
    Peixin Yang
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 198:130.e1-7. 2008
    ..To establish a link between oxidative stress signaling and diabetic embryopathy, levels of phosphorylated-p66Shc (which is a key signaling molecule that mediates oxidative stress-induced apoptosis) were evaluated...
  10. doi request reprint Blockade of c-Jun N-terminal kinase activation abrogates hyperglycemia-induced yolk sac vasculopathy in vitro
    Peixin Yang
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Obstet Gynecol 198:321.e1-7. 2008
    ..In addition, during embryopathy, teratogen such as hyperglycemia is associated with concomitant injury to the yolk sac and embryo...