Yong Zhao

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 West Polk Street, Chicago, IL 60612, USA
    BMC Med 10:3. 2012
  2. ncbi request reprint Identification of stem cells from human umbilical cord blood with embryonic and hematopoietic characteristics
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, IL 60612, USA
    Exp Cell Res 312:2454-64. 2006
  3. ncbi request reprint A unique human blood-derived cell population displays high potential for producing insulin
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 W Polk Street, Chicago, IL 60612, USA
    Biochem Biophys Res Commun 360:205-11. 2007
  4. pmc Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice
    Yong Zhao
    Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 4:e4226. 2009
  5. ncbi request reprint Immune modulation of blood-derived stem cell as a comprehensive tool for treating type 1 diabetes
    Yong Zhao
    Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Discov Med 8:219-22. 2009
  6. ncbi request reprint Human umbilical cord blood-derived f-macrophages retain pluripotentiality after thrombopoietin expansion
    Yong Zhao
    Section of Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 W Polk Street, Chicago, IL 60612, USA
    Exp Cell Res 310:311-8. 2005
  7. doi request reprint New type of human blood stem cell: a double-edged sword for the treatment of type 1 diabetes
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Transl Res 155:211-6. 2010
  8. doi request reprint Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model
    Yong Zhao
    Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Biochem Biophys Res Commun 399:629-36. 2010
  9. doi request reprint Human cord blood stem cells and the journey to a cure for type 1 diabetes
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Autoimmun Rev 10:103-7. 2010
  10. doi request reprint New hope for type 2 diabetics: targeting insulin resistance through the immune modulation of stem cells
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Autoimmun Rev 11:137-42. 2011

Collaborators

Detail Information

Publications53

  1. pmc Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 West Polk Street, Chicago, IL 60612, USA
    BMC Med 10:3. 2012
    ....
  2. ncbi request reprint Identification of stem cells from human umbilical cord blood with embryonic and hematopoietic characteristics
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, IL 60612, USA
    Exp Cell Res 312:2454-64. 2006
    ..These findings may have significant potential to advance stem-cell-based therapeutics...
  3. ncbi request reprint A unique human blood-derived cell population displays high potential for producing insulin
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 W Polk Street, Chicago, IL 60612, USA
    Biochem Biophys Res Commun 360:205-11. 2007
    ..These findings may open up new avenues for autologous blood stem cell-based therapies for diabetes...
  4. pmc Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice
    Yong Zhao
    Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 4:e4226. 2009
    ..Regulatory T cells (Tregs) play a pivotal role in maintaining self-tolerance through their inhibitory impact on autoreactive effector T cells. An abnormality of Tregs is associated with initiation of progression of T1D...
  5. ncbi request reprint Immune modulation of blood-derived stem cell as a comprehensive tool for treating type 1 diabetes
    Yong Zhao
    Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Discov Med 8:219-22. 2009
    ..Blood-derived new stem cells have shown promise in both aspects of this treatment...
  6. ncbi request reprint Human umbilical cord blood-derived f-macrophages retain pluripotentiality after thrombopoietin expansion
    Yong Zhao
    Section of Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 W Polk Street, Chicago, IL 60612, USA
    Exp Cell Res 310:311-8. 2005
    ..These findings demonstrate a potential use of CB f-Mphi and may lead to develop new therapeutic strategy for treating dominant disease...
  7. doi request reprint New type of human blood stem cell: a double-edged sword for the treatment of type 1 diabetes
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Transl Res 155:211-6. 2010
    ..These new stem cells will offer a promising avenue for the development of powerful autologous therapeutic products for prevention and reversal of T1D...
  8. doi request reprint Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model
    Yong Zhao
    Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Biochem Biophys Res Commun 399:629-36. 2010
    ..This model can provide a valuable tool for translational research into T1D...
  9. doi request reprint Human cord blood stem cells and the journey to a cure for type 1 diabetes
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Autoimmun Rev 10:103-7. 2010
    ....
  10. doi request reprint New hope for type 2 diabetics: targeting insulin resistance through the immune modulation of stem cells
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Autoimmun Rev 11:137-42. 2011
    ..This review focuses on recent progress in the use of immune modulation in T2D and discusses the potential for future therapies. New insights are provided on the use of cord blood-derived multipotent stem cells (CB-SC) in T2D...
  11. ncbi request reprint Immune regulation of T lymphocyte by a newly characterized human umbilical cord blood stem cell
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 W Polk Street, Chicago, IL 60612, USA
    Immunol Lett 108:78-87. 2007
    ..Our findings may advance our understanding of the immunobiology of stem cells and facilitate the therapeutic application of cord blood stem cells...
  12. pmc Targeting insulin resistance in type 2 diabetes via immune modulation of cord blood-derived multipotent stem cells (CB-SCs) in stem cell educator therapy: phase I/II clinical trial
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 W, Polk Street, Chicago, IL 60612, USA
    BMC Med 11:160. 2013
    ..It suggests that immune modulation may be a useful tool in treating the disease...
  13. ncbi request reprint New hope for diabetics: adult blood stem cells can make insulin
    Yong Zhao
    Department of Medicine, University of Illinois School of Medicine, Chicago, IL 60612, USA
    Discov Med 7:63-7. 2007
    ..Clinical application of these autologous blood-derived insulin-producing cells holds great promise for diabetic treatment...
  14. doi request reprint Stem cell educator therapy and induction of immune balance
    Yong Zhao
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Curr Diab Rep 12:517-23. 2012
    ..Our clinical trial reveals that a single treatment with the Stem Cell Educator provides lasting reversal of autoimmunity that allows regeneration of islet β cells and improvement of metabolic control in subjects with long-standing T1D...
  15. pmc Hyperglycemia and advanced glycosylation end products suppress adipocyte apoE expression: implications for adipocyte triglyceride metabolism
    Doris Joy Espiritu
    Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Am J Physiol Endocrinol Metab 299:E615-23. 2010
    ..In vivo results using adipose tissue transplantation suggest that reduction of adipocyte apoE, and subsequent reduction of adipocyte triglyceride accumulation, could influence lipid accumulation in nonadipose tissue...
  16. ncbi request reprint Spermine acts as a negative regulator of macrophage differentiation in human myeloid leukemia cells
    Igor M Gavin
    Biochip Technology Center, Argonne National Laboratory, Argonne, Illinois, USA
    Cancer Res 64:7432-8. 2004
    ..The present studies raise the possibility that agents able to reduce spermine levels in patients' myeloid leukemia cells may enhance the activity of differentiation therapy drugs for this type of leukemia...
  17. doi request reprint Diabetes-induced alteration of F4/80+ macrophages: a study in mice with streptozotocin-induced diabetes for a long term
    Haixia Ma
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Datun Road, Chaoyang, Beijing 100101, China
    J Mol Med (Berl) 86:391-400. 2008
    ....
  18. ncbi request reprint B and T lymphocyte attenuator interacts with CD3zeta and inhibits tyrosine phosphorylation of TCRzeta complex during T-cell activation
    Ting He Wu
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    Immunol Cell Biol 85:590-5. 2007
    ..These results suggest that BTLA functions to regulate T-cell signaling by controlling the phosphorylated form of TCRzeta accumulation in the lipid raft...
  19. ncbi request reprint The immunity of splenic and peritoneal F4/80(+) resident macrophages in mouse mixed allogeneic chimeras
    Guangwei Liu
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beisihuan Xi Road 25, Beijing, 100080, China
    J Mol Med (Berl) 85:1125-35. 2007
    ..The present study also, for the first time, offered basic information for macrophages maturing in heterogeneous environments...
  20. ncbi request reprint The macrophage heterogeneity: difference between mouse peritoneal exudate and splenic F4/80+ macrophages
    Guangwei Liu
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    J Cell Physiol 209:341-52. 2006
    ....
  21. ncbi request reprint Dendritic cells induced in the presence of GM-CSF and IL-5
    Huanfa Yi
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    Cytokine 37:35-43. 2007
    ..Together, these data suggest that IL-5 could partially inhibit GM-CSF-induced DC differentiation which could be reversed by IL-4 in vitro...
  22. ncbi request reprint The influence of cyclosporin A on lymphocyte attenuator expression
    Chun Zeng
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    J Autoimmun 28:234-44. 2007
    ....
  23. ncbi request reprint NK cell tolerance in mixed allogeneic chimeras
    Yong Zhao
    Bone Marrow Transplantation Section, Transplantation Biology Research Center, Surgical Service, Massachusetts General Hospital Harvard Medical School, Boston, MA 02129, USA
    J Immunol 170:5398-405. 2003
    ..Thus, the present studies demonstrate that NK cells in mixed chimeras are stably tolerant to both donor and host Ags, by mechanisms that are as yet unexplained...
  24. pmc A human peripheral blood monocyte-derived subset acts as pluripotent stem cells
    Yong Zhao
    Biochip Technology Center, Argonne National Laboratory, Argonne, IL 60439, USA
    Proc Natl Acad Sci U S A 100:2426-31. 2003
    ..The ability to store, expand, and differentiate these PSC from autologous peripheral blood should make them valuable candidates for transplantation therapy...
  25. ncbi request reprint The nonopsonic allogeneic cell phagocytosis of macrophages detected by flow cytometry and two photon fluorescence microscope
    Guang Wei Liu
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    Transpl Immunol 16:220-6. 2006
    ..Our present data indicated that the FCM and TPM combined method is a practical approach to detect macrophage nonopsonic phagocytosis of allogeneic lymphocytes and to identify the phenotype alteration of macrophages after phagocytosis...
  26. ncbi request reprint Xenogeneic skin graft rejection in M-CSF/macrophage deficient osteopetrotic mice
    Yong Zhao
    Department of Surgery, University of Nebraska Medical Center, The Lied Transplant Center, Omaha, NE 68198 7690, USA
    Xenotransplantation 10:232-9. 2003
    ..The cellular infiltrate in xenografts suggests that macrophages may be involved in xenograft rejection. However, the precise role of macrophages in xenograft rejection has not yet been fully addressed...
  27. doi request reprint The inflammatory Th 17 subset in immunity against self and non-self antigens
    Di Jin
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, PR China
    Autoimmunity 41:154-62. 2008
    ....
  28. doi request reprint The effects of antibody treatment on regulatory CD4(+)CD25(+) T cells
    Huanfa Yi
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    Transpl Immunol 19:37-44. 2008
    ..In this manuscript, we review the recent progress on the effects of therapeutic antibodies on the development, phenotypic changes and functions of CD4(+)CD25(+) Tregs...
  29. ncbi request reprint Inhibition of cell growth and induction of G1-phase cell cycle arrest in hepatoma cells by steroid extract from Meretrix meretrix
    Ting He Wu
    Laboratory of Marine Biotechnology, Department of Biological Science and Biotechnology, Tsinghua University, Beijing 100084, People s Republic of China
    Cancer Lett 232:199-205. 2006
    ..In conclusion, MME induces G1 phase cell cycle arrest via both p53-dependent and p53-independent pathways...
  30. ncbi request reprint Murine CD4 T cells selected in a highly disparate xenogeneic porcine thymus graft do not show rapid decay in the absence of selecting MHC in the periphery
    Jose Ignacio Rodriguez-Barbosa
    Transplantation Biology Research Center, Bone Marrow Transplantation Section, Surgical Service, Massachusetts General Hospital Harvard Medical School, Boston, MA 02129, USA
    J Immunol 169:6697-710. 2002
    ..Our results support the interpretation that xenogeneic thymic transplantation is a feasible strategy to reconstitute CD4 T cells and render recipients tolerant of a xenogeneic donor...
  31. doi request reprint Immunotoxic effects of perfluorononanoic acid on BALB/c mice
    Xuemei Fang
    Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100190, China
    Toxicol Sci 105:312-21. 2008
    ..Interestingly, at the transcriptional level, the nuclear factor-kappa B signaling pathway appears to be uninvolved in the immunotoxic potential of PFNA...
  32. doi request reprint The differentiation-inducing effect of Nordy on HPV-16 subgenes-immortalized human endocervical cells H8
    Jing Zhao
    Department of Pathology, Chongqing Medical University, Chongqing, PR China
    Anticancer Drugs 19:713-9. 2008
    ..Taken together, Nordy could suppress proliferation by inhibiting proliferation-related events and promote cell differentiation in H8 cell. The results suggested that Nordy might be a potential tumor therapeutic agent...
  33. ncbi request reprint BTLA, a new inhibitory B7 family receptor with a TNFR family ligand
    Chun Zeng
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China
    Cell Mol Immunol 2:427-32. 2005
    ..The exploration of the biological mechanisms and regulation of BTLA will open possibilities on novel therapeutic strategies in immune-related diseases...
  34. ncbi request reprint Altered allogeneic immune responses in middle-aged mice
    Yimin Sun
    Department of Surgery, University of Nebraska Medical Center, The Lied Transplant Center, UNMC, Omaha, NE 68198 7690, USA
    Cell Mol Immunol 1:440-6. 2004
    ..Further studies on the characteristics of allogeneic immunity in aging individuals may help to determine the appropriated treatment for transplant aging individuals...
  35. ncbi request reprint Tolerance by selective in vivo expansion of foreign major histocompatibility complex-transduced autologous bone marrow
    Jia Lin Zhang
    Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska 68198 3285, USA
    Transplantation 80:362-9. 2005
    ..Selective expansion of transduced hematopoietic stem cells has been accomplished by incorporating the dihydrofolate reductase (DHFR) gene into the gene transfer vector...
  36. ncbi request reprint Prolongation of allogeneic skin graft survival by injection of anti-Ly49A monoclonal antibody YE1/48
    Tian Yu Yang
    Department of Surgery, University of Nebraska Medical Center, The Lied Transplant Center, 987690 University of Nebraska Medical Center, Omaha, NE 68198 7690, USA
    Clin Immunol 106:148-54. 2003
    ..The presence of NK, NKT cells, and some cytotoxic T cells may be essential for YE1/48-mediated immunosuppression in vivo...
  37. pmc MOP3, a component of the molecular clock, regulates the development of B cells
    Yimin Sun
    Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA
    Immunology 119:451-60. 2006
    ..This study also showed a connection between a master regular of circadian rhythm with B-cell development in mice...
  38. pmc Transcription factor FOXO3a mediates apoptosis in HIV-1-infected macrophages
    Min Cui
    Laboratory of Neurotoxicology, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha 68198, USA
    J Immunol 180:898-906. 2008
    ..Understanding the PI3K/Akt-1/FOXO3a pathway and its associated death mechanism in macrophages during HIV-1 infection would lead to identification of potential therapeutic avenues for the treatment of HIV-1 infection...
  39. ncbi request reprint Compatibility of porcine and human interleukin 2: implications for xenotransplantation
    Baojun Zhang
    State Key Laboratory of Biomembrane and Membrane Biotechnology, Transplantation Biology Research Division, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    Xenotransplantation 13:423-32. 2006
    ..Therefore, it is essential to understand of the compatibility of IL2 between pigs and humans...
  40. ncbi request reprint Thymic epithelial progenitor cells and thymus regeneration: an update
    Lianjun Zhang
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China
    Cell Res 17:50-5. 2007
    ..Great progress has been made to characterize the common TEC progenitor cells in recent years. We herein discuss the sole origin paradigm with regard to TEC differentiation as well as these progenitor cells in thymus regeneration...
  41. ncbi request reprint Transforming growth factor-beta: an important role in CD4+CD25+ regulatory T cells and immune tolerance
    Lianjun Zhang
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, People s Republic of China
    Autoimmunity 39:269-76. 2006
    ..We will, herein, focus on the crucial role of TGF-beta signaling in Treg cell biology and summarize the current studies regarding TGF-beta in the generation and function of CD4+CD25+Treg cells both in vivo and in vitro...
  42. ncbi request reprint A novel approach to generate host antitumor T cells: adoptive immunotherapy by T cells maturing in xenogeneic thymus
    Yong Zhao
    Transplantation Biology Research Division, The State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences
    J Immunother 30:83-8. 2007
    ..This study may offer a novel resource to produce host antitumor T cells for adoptive immunotherapy of tumor patients...
  43. ncbi request reprint The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice
    Yanyan Qu
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beisihuan Xi Road 25, Beijing, 100080, China
    Transpl Immunol 17:153-61. 2007
    ..The different effects of rapa on CD4(+)CD25(+)Treg and T effector cells make rapa to be a favorable choice for inducing immune tolerance to self-, allo-, or xeno-antigens...
  44. ncbi request reprint Changes of CD4+CD25+Foxp3+ regulatory T cells in aged Balb/c mice
    Liang Zhao
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beisihuan Xi Road 25, Beijing, China 100080
    J Leukoc Biol 81:1386-94. 2007
    ..The functional defects of CD4(+)CD25(+) Treg cells may shed light on the role of CD4(+)CD25(+) Treg cells in the increased sensitivity to autoimmune diseases of aged populations...
  45. ncbi request reprint Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2
    Yong Zhao
    Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA
    Cell 129:303-17. 2007
    ..These findings indicate that subtle alteration of miRNA dosage can have profound consequences in mammals and demonstrate the utility of mammalian loss-of-function models in revealing physiologic miRNA targets...
  46. ncbi request reprint Allograft inflammatory factor-1 and its immune regulation
    Guangwei Liu
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beisihuan Xi Road 25, Beijing 100080, China
    Autoimmunity 40:95-102. 2007
    ..In the present manuscript, the genomic and functional characteristics of AIF-1 family proteins as well as their immune regulatory effects are reviewed...
  47. ncbi request reprint Beneficial effects of losartan on vascular injury induced by advanced glycosylation end products and their receptors in spontaneous hypertension rats
    Wei Wei Zhu
    Department of Geratology, Shandong Provincial Hospital of Shandong University, No 324 Road, Jinan, Shandong, P R China
    Mol Cell Biochem 304:35-43. 2007
    ....
  48. ncbi request reprint Regulatory CD4(+)CD25(+) T-cells are controlled by multiple pathways at multiple levels
    Yanyan Qu
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    Int Rev Immunol 26:145-60. 2007
    ....
  49. ncbi request reprint The two simultaneously occurring processes in one immune response: the positive immune reaction and immune tolerance
    Yong Zhao
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beisihuan Xi Road 25, Beijing 100080, China
    Med Hypotheses 67:1384-5. 2006
    ..On the other hand, it will impact the immunotherapy for tumors and the development of vaccines...
  50. ncbi request reprint Transplant tolerance: is it really free of concerns?
    Yong Zhao
    Trends Immunol 28:376-7. 2007
  51. ncbi request reprint The biological role of dectin-1 in immune response
    Lina Sun
    Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Datui Road Yi 5, Beijing 100101, China
    Int Rev Immunol 26:349-64. 2007
    ..In addition, dectin-1 is involved in the adaptive immune response as well as autoimmune diseases and immune tolerance. In this paper, we will mainly focus on the characteristics of dectin-1 and its biological role in immune response...
  52. pmc Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms
    G Matthew Longo
    Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska 68198 7690, USA
    J Clin Invest 110:625-32. 2002
    ..These findings suggest that macrophage-derived MMP-9 and mesenchymal cell MMP-2 are both required and work in concert to produce AAA...
  53. doi request reprint Bioimaging nitric oxide in activated macrophages in vitro and hepatic inflammation in vivo based on a copper-naphthoimidazol coordination compound
    Jie Ouyang
    The School of Chemistry and Chemical Engineering, Tianjin University of Technology, 263 Hongqi South Road, Tianjin 300191, China
    Nitric Oxide 19:42-9. 2008
    ....