Affiliation: University of Chicago
- Modification-specific proteomics: strategies for characterization of post-translational modifications using enrichment techniquesYingming Zhao
The Ben May Department for Cancer Research, The University of Chicago, Chicago, IL, USA
Proteomics 9:4632-41. 2009..We review some of the current strategies employed for enrichment and detection of PTMs in modification-specific proteomics...
- Tetrandrine inhibits Wnt/β-catenin signaling and suppresses tumor growth of human colorectal cancerBai Cheng He
Department of Pharmacology and the Key Laboratory of Diagnostic Medicine designated by Chinese Ministry of Education, Chongqing Medical University, Chongqing, China
Mol Pharmacol 79:211-9. 2011..Thus, our findings strongly suggest that the anticancer effect of TET in colon cancer may be at least in part mediated by targeting β-catenin activity. Therefore, TET may be used alone or in combination as an effective anticancer agent...
- Phosphorylation of Bad at Thr-201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1Hongbin Deng
Ben May Department for Cancer Research, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA
J Biol Chem 283:20754-60. 2008..Thus, our results provide a novel molecular mechanism by which JNK1 promotes glycolysis for cell survival...