X Zhao

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi (6-4) photolyase: light-dependent repair of DNA damage
    X Zhao
    Department of Biochemistry and Biophysics, School of Medicine, University of North Carolina, Chapel Hill 27599 7260, USA
    Histol Histopathol 13:1179-82. 1998
  2. ncbi Reaction mechanism of (6-4) photolyase
    X Zhao
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7260, USA
    J Biol Chem 272:32580-90. 1997
  3. ncbi Protective effect of melatonin and catalase in bovine neutrophil-induced model of mammary cell damage
    V Boulanger
    Dairy and Swine Research and Development Centre, Agriculture Agri Food Canada, Lennoxville, Quebec
    J Dairy Sci 85:562-9. 2002
  4. ncbi Retinoic acid receptor-independent mechanism of apoptosis of melanoma cells by the retinoid CD437 (AHPN)
    X Zhao
    Department of Otolaryngology, Cancer Research Center, Boston University School of Medicine, 75 Albany Street R903, Boston, MA 02118, USA
    Cell Death Differ 8:878-86. 2001
  5. pmc The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage
    X Zhao
    Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, 701 West 168th Street, New York, NY 10032, USA
    EMBO J 20:3544-53. 2001
  6. ncbi Site-directed mutagenesis of human membrane-associated ganglioside sialidase: identification of amino-acid residues contributing to substrate specificity
    Y Wang
    Division of Biochemistry, Research Institute, Miyagi Prefectural Cancer Center, Natori, Miyagi, Japan
    Eur J Biochem 268:2201-8. 2001
  7. ncbi The effect of methylation outside the recognition sequence of restriction endonuclease PvuII on its cleavage efficiency
    Q Liu
    Institute for Molecular Biology, Nankai University, Tianjin, People s Republic of China
    Gene 113:89-93. 1992
  8. ncbi A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools
    X Zhao
    Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, New York, New York 10032 2704, USA
    Mol Cell 2:329-40. 1998
  9. ncbi Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins
    D S Hsu
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill 27599, USA
    Biochemistry 35:13871-7. 1996
  10. ncbi Structural and enzymatic aspects of rhodopsin phosphorylation
    H Ohguro
    Department of Ophthalmology, School of Medicine, University of Washington, Seattle, 98195, USA
    J Biol Chem 271:5215-24. 1996

Collaborators

  • A Sancar
  • T Todo
  • A Chabes
  • J Mehrzad
  • P Lacasse
  • V Boulanger
  • Y Wang
  • K Lauzon
  • C Desrosiers
  • G Robitaille
  • D S Hsu
  • H Ohguro
  • T Miyagi
  • K Yamaguchi
  • Y Shimada
  • J BuczyƂko
  • J A Taylor
  • K A Walsh
  • S Zhao
  • A Kazantsev
  • R P Wang
  • Y F Wei
  • K Palczewski
  • M Rudnicka-Nawrot
  • Q Liu
  • Y Chen
  • D Chen
  • X Chen

Detail Information

Publications11

  1. ncbi (6-4) photolyase: light-dependent repair of DNA damage
    X Zhao
    Department of Biochemistry and Biophysics, School of Medicine, University of North Carolina, Chapel Hill 27599 7260, USA
    Histol Histopathol 13:1179-82. 1998
    ....
  2. ncbi Reaction mechanism of (6-4) photolyase
    X Zhao
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7260, USA
    J Biol Chem 272:32580-90. 1997
    ..Taken together, the data are consistent with photoinduced electron transfer from reduced FAD to substrate, in a manner analogous to the cyclobutane pyrimidine dimer photolyase...
  3. ncbi Protective effect of melatonin and catalase in bovine neutrophil-induced model of mammary cell damage
    V Boulanger
    Dairy and Swine Research and Development Centre, Agriculture Agri Food Canada, Lennoxville, Quebec
    J Dairy Sci 85:562-9. 2002
    ..Our results suggest that hydroxyl radicals released by activated bovine neutrophils cause damage to mammary epithelial cells and that antioxidants may be useful to protect the mammary tissue during bovine mastitis...
  4. ncbi Retinoic acid receptor-independent mechanism of apoptosis of melanoma cells by the retinoid CD437 (AHPN)
    X Zhao
    Department of Otolaryngology, Cancer Research Center, Boston University School of Medicine, 75 Albany Street R903, Boston, MA 02118, USA
    Cell Death Differ 8:878-86. 2001
    ..CD437-mediated DNA adduct-formation may also explain its apoptotic effects in other cell types...
  5. pmc The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage
    X Zhao
    Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, 701 West 168th Street, New York, NY 10032, USA
    EMBO J 20:3544-53. 2001
    ..Therefore, Sml1 is a new target of the DNA damage checkpoint and its removal is a conserved function of Mec1 and Rad53 during growth and after damage...
  6. ncbi Site-directed mutagenesis of human membrane-associated ganglioside sialidase: identification of amino-acid residues contributing to substrate specificity
    Y Wang
    Division of Biochemistry, Research Institute, Miyagi Prefectural Cancer Center, Natori, Miyagi, Japan
    Eur J Biochem 268:2201-8. 2001
    ..The findings suggest that putative active-site residues of the human membrane sialidase contribute to its substrate specificity...
  7. ncbi The effect of methylation outside the recognition sequence of restriction endonuclease PvuII on its cleavage efficiency
    Q Liu
    Institute for Molecular Biology, Nankai University, Tianjin, People s Republic of China
    Gene 113:89-93. 1992
    ..We suggest that a new parameter, involving methylation of sites outside the recognition sequence, be considered in kinetic experiments on cleavage...
  8. ncbi A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools
    X Zhao
    Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, New York, New York 10032 2704, USA
    Mol Cell 2:329-40. 1998
    ..Finally, both in vivo and in vitro experiments show that Sml1 binds to Rnr1. We propose that Sml1 inhibits dNTP synthesis posttranslationally by binding directly to Rnr1 and that Mec1 and Rad53 are required to relieve this inhibition...
  9. ncbi Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins
    D S Hsu
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill 27599, USA
    Biochemistry 35:13871-7. 1996
    ..We conclude that these newly discovered members of the photolyase/photoreceptor family are not photolyases and instead may function as blue-light photoreceptors in humans...
  10. ncbi Structural and enzymatic aspects of rhodopsin phosphorylation
    H Ohguro
    Department of Ophthalmology, School of Medicine, University of Washington, Seattle, 98195, USA
    J Biol Chem 271:5215-24. 1996
    ..These data provide a molecular mechanism for the site-specific phosphorylation of Rho observed in vivo...
  11. ncbi Proteases involved in mammary tissue damage during endotoxin-induced mastitis in dairy cows
    J Mehrzad
    Dairy and Swine Research and Development Centre, Agriculture and Agri Food Canada, Lennoxville, QC, J1M 1Z3, Canada
    J Dairy Sci 88:211-22. 2005
    ..These results suggest that proteases released by PMN are actively involved in udder tissue damage during mastitis...