- (6-4) photolyase: light-dependent repair of DNA damage
Department of Biochemistry and Biophysics, School of Medicine, University of North Carolina, Chapel Hill 27599 7260, USA
Histol Histopathol 13:1179-82. 1998
- Reaction mechanism of (6-4) photolyase
Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7260, USA
J Biol Chem 272:32580-90. 1997
..Taken together, the data are consistent with photoinduced electron transfer from reduced FAD to substrate, in a manner analogous to the cyclobutane pyrimidine dimer photolyase...
- Protective effect of melatonin and catalase in bovine neutrophil-induced model of mammary cell damage
Dairy and Swine Research and Development Centre, Agriculture Agri Food Canada, Lennoxville, Quebec
J Dairy Sci 85:562-9. 2002
..Our results suggest that hydroxyl radicals released by activated bovine neutrophils cause damage to mammary epithelial cells and that antioxidants may be useful to protect the mammary tissue during bovine mastitis...
- Retinoic acid receptor-independent mechanism of apoptosis of melanoma cells by the retinoid CD437 (AHPN)
Department of Otolaryngology, Cancer Research Center, Boston University School of Medicine, 75 Albany Street R903, Boston, MA 02118, USA
Cell Death Differ 8:878-86. 2001
..CD437-mediated DNA adduct-formation may also explain its apoptotic effects in other cell types...
- The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage
Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, 701 West 168th Street, New York, NY 10032, USA
EMBO J 20:3544-53. 2001
..Therefore, Sml1 is a new target of the DNA damage checkpoint and its removal is a conserved function of Mec1 and Rad53 during growth and after damage...
- Site-directed mutagenesis of human membrane-associated ganglioside sialidase: identification of amino-acid residues contributing to substrate specificity
Division of Biochemistry, Research Institute, Miyagi Prefectural Cancer Center, Natori, Miyagi, Japan
Eur J Biochem 268:2201-8. 2001
..The findings suggest that putative active-site residues of the human membrane sialidase contribute to its substrate specificity...
- The effect of methylation outside the recognition sequence of restriction endonuclease PvuII on its cleavage efficiency
Institute for Molecular Biology, Nankai University, Tianjin, People s Republic of China
Gene 113:89-93. 1992
..We suggest that a new parameter, involving methylation of sites outside the recognition sequence, be considered in kinetic experiments on cleavage...
- A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools
Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, New York, New York 10032 2704, USA
Mol Cell 2:329-40. 1998
..Finally, both in vivo and in vitro experiments show that Sml1 binds to Rnr1. We propose that Sml1 inhibits dNTP synthesis posttranslationally by binding directly to Rnr1 and that Mec1 and Rad53 are required to relieve this inhibition...
- Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins
D S Hsu
Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill 27599, USA
Biochemistry 35:13871-7. 1996
..We conclude that these newly discovered members of the photolyase/photoreceptor family are not photolyases and instead may function as blue-light photoreceptors in humans...
- Structural and enzymatic aspects of rhodopsin phosphorylation
Department of Ophthalmology, School of Medicine, University of Washington, Seattle, 98195, USA
J Biol Chem 271:5215-24. 1996
..These data provide a molecular mechanism for the site-specific phosphorylation of Rho observed in vivo...
- Proteases involved in mammary tissue damage during endotoxin-induced mastitis in dairy cows
Dairy and Swine Research and Development Centre, Agriculture and Agri Food Canada, Lennoxville, QC, J1M 1Z3, Canada
J Dairy Sci 88:211-22. 2005
..These results suggest that proteases released by PMN are actively involved in udder tissue damage during mastitis...