Min Zhao

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Electrical fields in wound healing-An overriding signal that directs cell migration
    Min Zhao
    Department of Dermatology, University of California Davis, School of Medicine, Center for Neurosciences, 1515 Newton Ct, Davis, CA 95618 4859, USA
    Semin Cell Dev Biol 20:674-82. 2009
  2. ncbi Electrical signaling in control of ocular cell behaviors
    Min Zhao
    Department of Dermatology, UC Davis School of Medicine, 2921 Stockton Blvd, Sacramento, CA 95817, USA
    Prog Retin Eye Res 31:65-88. 2012
  3. ncbi Airway epithelial wounds in rhesus monkey generate ionic currents that guide cell migration to promote healing
    Yao Hui Sun
    Department of Dermatology, School of Medicine, Univ of California at Davis CA, Sacramento, CA 95817, USA
    J Appl Physiol 111:1031-41. 2011
  4. ncbi Downregulation of PTEN at corneal wound sites accelerates wound healing through increased cell migration
    Lin Cao
    Department of Dermatology, School of Medicine, University of California, Davis, California 95817, USA
    Invest Ophthalmol Vis Sci 52:2272-8. 2011
  5. ncbi GSK-3β is essential for physiological electric field-directed Golgi polarization and optimal electrotaxis
    Lin Cao
    Department of Dermatology, University of California, Davis, CA 95618, USA
    Cell Mol Life Sci 68:3081-93. 2011
  6. ncbi Ionic components of electric current at rat corneal wounds
    Ana Carolina Vieira
    Department of Ophthalmology, University of California Davis, Davis, California, United States of America
    PLoS ONE 6:e17411. 2011
  7. ncbi E-cadherin plays an essential role in collective directional migration of large epithelial sheets
    Li Li
    Department of Dermatology, School of Medicine, Institute for Regenerative Cures, University of California at Davis, Suite 1630, 2921 Stockton Blvd, Room 1617, Sacramento, CA 95817, USA
    Cell Mol Life Sci 69:2779-89. 2012
  8. ncbi Modulating endogenous electric currents in human corneal wounds--a novel approach of bioelectric stimulation without electrodes
    Brian Reid
    Dermatology and Ophthalmology Research, Institute for Regenerative Cures, University of California Davis School of Medicine, Sacramento, CA 95817, USA
    Cornea 30:338-43. 2011
  9. ncbi Different roles of membrane potentials in electrotaxis and chemotaxis of dictyostelium cells
    Run Chi Gao
    University of California, 2921 Stockton Blvd, Sacramento, CA 95817, USA
    Eukaryot Cell 10:1251-6. 2011
  10. ncbi Endogenous electric currents might guide rostral migration of neuroblasts
    Lin Cao
    Department of Dermatology, University of California, Davis, 3301 C Street, Sacramento, California 95816, USA
    EMBO Rep 14:184-90. 2013

Research Grants

  1. Ion Channels and Pumps: The Machinery of Electric Signaling at Corneal Wounds
    Min Zhao; Fiscal Year: 2010
  2. Ion Channels and Pumps: The Machinery of Electric Signaling at Corneal Wounds
    Min Zhao; Fiscal Year: 2011

Collaborators

Detail Information

Publications14

  1. ncbi Electrical fields in wound healing-An overriding signal that directs cell migration
    Min Zhao
    Department of Dermatology, University of California Davis, School of Medicine, Center for Neurosciences, 1515 Newton Ct, Davis, CA 95618 4859, USA
    Semin Cell Dev Biol 20:674-82. 2009
    ..One of the most challenging question is: How do cells sense the very weak electric signals? Clinically, it is highly desirable to develop practical and reliable technologies for wound healing management exploiting the electric signaling...
  2. ncbi Electrical signaling in control of ocular cell behaviors
    Min Zhao
    Department of Dermatology, UC Davis School of Medicine, 2921 Stockton Blvd, Sacramento, CA 95817, USA
    Prog Retin Eye Res 31:65-88. 2012
    ....
  3. ncbi Airway epithelial wounds in rhesus monkey generate ionic currents that guide cell migration to promote healing
    Yao Hui Sun
    Department of Dermatology, School of Medicine, Univ of California at Davis CA, Sacramento, CA 95817, USA
    J Appl Physiol 111:1031-41. 2011
    ..Manipulation of ion transport may lead to novel therapeutic approaches to repair damaged respiratory epithelium...
  4. ncbi Downregulation of PTEN at corneal wound sites accelerates wound healing through increased cell migration
    Lin Cao
    Department of Dermatology, School of Medicine, University of California, Davis, California 95817, USA
    Invest Ophthalmol Vis Sci 52:2272-8. 2011
    ..The authors therefore hypothesized that wounding would downregulate PTEN and that this downregulation would enhance wound healing...
  5. ncbi GSK-3β is essential for physiological electric field-directed Golgi polarization and optimal electrotaxis
    Lin Cao
    Department of Dermatology, University of California, Davis, CA 95618, USA
    Cell Mol Life Sci 68:3081-93. 2011
    ..Those results suggest that GSK-3β is essential for physiological EF-induced Golgi apparatus (GA) polarization and optimal electrotactic cell migration...
  6. ncbi Ionic components of electric current at rat corneal wounds
    Ana Carolina Vieira
    Department of Ophthalmology, University of California Davis, Davis, California, United States of America
    PLoS ONE 6:e17411. 2011
    ..Could these fields be actively maintained and regulated as an active wound response? What are the molecular, ionic and cellular mechanisms underlying the wound electric currents?..
  7. ncbi E-cadherin plays an essential role in collective directional migration of large epithelial sheets
    Li Li
    Department of Dermatology, School of Medicine, Institute for Regenerative Cures, University of California at Davis, Suite 1630, 2921 Stockton Blvd, Room 1617, Sacramento, CA 95817, USA
    Cell Mol Life Sci 69:2779-89. 2012
    ..Our study thus identifies a novel mechanism--E-cadherin dependence and coordinated traction forces of leading cells in collective directional migration of large epithelial sheets...
  8. ncbi Modulating endogenous electric currents in human corneal wounds--a novel approach of bioelectric stimulation without electrodes
    Brian Reid
    Dermatology and Ophthalmology Research, Institute for Regenerative Cures, University of California Davis School of Medicine, Sacramento, CA 95817, USA
    Cornea 30:338-43. 2011
    ..To measure electric current in human corneal wounds and test the feasibility of pharmacologically enhancing the current to promote corneal wound healing...
  9. ncbi Different roles of membrane potentials in electrotaxis and chemotaxis of dictyostelium cells
    Run Chi Gao
    University of California, 2921 Stockton Blvd, Sacramento, CA 95817, USA
    Eukaryot Cell 10:1251-6. 2011
    ..The initial directional sensing mechanisms for electrotaxis therefore differ from those of chemotaxis and may be mediated by changes in resting V(m)...
  10. ncbi Endogenous electric currents might guide rostral migration of neuroblasts
    Lin Cao
    Department of Dermatology, University of California, Davis, 3301 C Street, Sacramento, California 95816, USA
    EMBO Rep 14:184-90. 2013
    ..The purinergic receptor P2Y1 mediates this migration. The results indicate that naturally occurring electric currents serve as a new guidance mechanism for rostral neuronal migration...
  11. ncbi Electrically guiding migration of human induced pluripotent stem cells
    Jiaping Zhang
    Department of Dermatology and Department of Ophthalmology, Institute for Regenerative Cures, UC Davis School of Medicine, Davis, CA 95817, USA
    Stem Cell Rev 7:987-96. 2011
    ..Our current finding may lead to techniques for applying EFs in vivo to guide migration of transplanted stem cells...
  12. ncbi Chloride channels and transporters in human corneal epithelium
    Lin Cao
    Department of Dermatology, University of California, Davis, CA 95618, USA
    Exp Eye Res 90:771-9. 2010
    ..Those molecules and their distribution may play important roles in maintaining resting Cl(-) fluxes and in regulating Cl(-) flux at corneal wounds, which may be a major contributor to wound electrical signaling...
  13. ncbi Beta-adrenergic receptor agonists delay while antagonists accelerate epithelial wound healing: evidence of an endogenous adrenergic network within the corneal epithelium
    Christine E Pullar
    Department of Dermatology, University of California Davis, Davis, California, USA
    J Cell Physiol 211:261-72. 2007
    ..Further investigation of this network will improve our understanding of one of the most frequently prescribed class of drugs...
  14. ncbi Electric currents in Xenopus tadpole tail regeneration
    Brian Reid
    Department of Dermatology, University of California, Davis CA 95616, USA
    Dev Biol 335:198-207. 2009
    ..These data suggest that electric signals might be one of the key players regulating regeneration...

Research Grants2

  1. Ion Channels and Pumps: The Machinery of Electric Signaling at Corneal Wounds
    Min Zhao; Fiscal Year: 2010
    ..The scientific knowledge to be acquired through this project, i.e. how cells regulate this fundamental signal, will open a new avenue to treat delayed and non-healing corneal wounds, and wounds in general. ..
  2. Ion Channels and Pumps: The Machinery of Electric Signaling at Corneal Wounds
    Min Zhao; Fiscal Year: 2011
    ..The scientific knowledge to be acquired through this project, i.e. how cells regulate this fundamental signal, will open a new avenue to treat delayed and non-healing corneal wounds, and wounds in general. ..