Jiyong Zhao

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint Coordination of DNA synthesis and histone gene expression during normal cell cycle progression and after DNA damage
    Jiyong Zhao
    Department of Biomedical Genetics, University of Rochester Medicial Center, New York 14642, USA
    Cell Cycle 3:695-7. 2004
  2. pmc Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition
    Michael DeRan
    Department of Biomedical Genetics, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Mol Cell Biol 28:435-47. 2008
  3. pmc DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway
    Chuan Su
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    EMBO J 23:1133-43. 2004
  4. pmc Assessing G1-to-S-phase progression after genotoxic stress
    Michael DeRan
    Department of Biomedical Genetics, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, New York 14642, USA
    Methods Mol Biol 782:221-30. 2011
  5. pmc Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A
    Mary Pulvino
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Blood 120:1668-77. 2012
  6. pmc NPAT expression is regulated by E2F and is essential for cell cycle progression
    Guang Gao
    Department of Biomedical Genetics, University of Rochester, Rochester, New York 14642, USA
    Mol Cell Biol 23:2821-33. 2003
  7. pmc Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit
    David A Barbie
    Massachusetts General Hospital Cancer Center, Charlestown, MA 02129, USA
    Mol Cell Biol 24:595-607. 2004
  8. ncbi request reprint Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway
    Xiao Feng Le
    Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cell Cycle 5:1654-61. 2006

Collaborators

  • Michael DeRan
  • Takashi Imai
  • Adrian P Bracken
  • Marie K Classon
  • Mary Pulvino
  • Guang Gao
  • Xiao Feng Le
  • David A Barbie
  • Chuan Su
  • David Oleksyn
  • Joel Shapiro
  • Yue Liang
  • Elise Van Pelt
  • Ignacio Sanz
  • Luojing Chen
  • Khandan Keyomarsi
  • Mong Hong Lee
  • Weiqun Mao
  • Mollianne Murray
  • Zhen Lu
  • Robert C Bast
  • Isabelle Bedrosian
  • MICHAEL A O'REILLY
  • Brian K Kennedy
  • Brett R Johnson
  • Richard Frock
  • Brian A Kudlow
  • Nicholas Dyson
  • Carsten Weiss
  • Ed Harlow
  • Dirk Bohmann
  • Sandra Schneider
  • Christopher Helt
  • Masashi Sagara
  • Kristian Helin
  • Diego Pasini
  • Claire Attwooll
  • Karina Burkard

Detail Information

Publications8

  1. ncbi request reprint Coordination of DNA synthesis and histone gene expression during normal cell cycle progression and after DNA damage
    Jiyong Zhao
    Department of Biomedical Genetics, University of Rochester Medicial Center, New York 14642, USA
    Cell Cycle 3:695-7. 2004
    ..Regulation of the cyclin E-Cdk2 substrate NPAT, which is essential for both histone gene expression and S phase entry, provides a mechanism coordinating histone and DNA synthesis in mammalian cells...
  2. pmc Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition
    Michael DeRan
    Department of Biomedical Genetics, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Mol Cell Biol 28:435-47. 2008
    ..Thus, our data support a model in which NPAT recruits the TRRAP-Tip60 complex to histone gene promoters to coordinate the transcriptional activation of multiple histone genes during the G(1)/S-phase transition...
  3. pmc DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway
    Chuan Su
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    EMBO J 23:1133-43. 2004
    ..Our results thus suggest that inhibition of Cdk2 activity following DNA damage results in the downregulation of histone gene transcription through dissociation of NPAT from histone gene clusters...
  4. pmc Assessing G1-to-S-phase progression after genotoxic stress
    Michael DeRan
    Department of Biomedical Genetics, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, New York 14642, USA
    Methods Mol Biol 782:221-30. 2011
    ..In this chapter we present methods for the induction of genotoxic stress. Additionally, we describe methods for studying the progression of cells from G(1) to S phase after genotoxic stress...
  5. pmc Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A
    Mary Pulvino
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Blood 120:1668-77. 2012
    ..The results of the present study indicate that Ubc13-Uev1A may represent a potential therapeutic target in DLBCL. In addition, compound NSC697923 may be exploited for the development of DLBCL therapeutic agents...
  6. pmc NPAT expression is regulated by E2F and is essential for cell cycle progression
    Guang Gao
    Department of Biomedical Genetics, University of Rochester, Rochester, New York 14642, USA
    Mol Cell Biol 23:2821-33. 2003
    ..As NPAT is involved in the regulation of S-phase-specific histone gene transcription, our findings indicate that NPAT links E2F to the activation of S-phase-specific histone gene transcription...
  7. pmc Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit
    David A Barbie
    Massachusetts General Hospital Cancer Center, Charlestown, MA 02129, USA
    Mol Cell Biol 24:595-607. 2004
    ..These results suggest that mammalian cells undergo a large-scale reorganization of chromatin during the rounds of DNA replication that precede cell cycle exit...
  8. ncbi request reprint Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway
    Xiao Feng Le
    Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cell Cycle 5:1654-61. 2006
    ....