Affiliation: University of Minnesota
Martin J, Cao S, Maldonado J, Zhang W, Mansky L. Distinct Particle Morphologies Revealed through Comparative Parallel Analyses of Retrovirus-Like Particles. J Virol. 2016;90:8074-84 pubmed publisher
..Distinct differences were observed, which enhances current knowledge of the retroviral assembly pathway. ..
Meissner M, MendonÃ§a L, Zhang W, Mansky L. Polymorphic Nature of Human T-Cell Leukemia Virus Type 1 Particle Cores as Revealed through Characterization of a Chronically Infected Cell Line. J Virol. 2017;91: pubmed publisher
..These findings have important implications for infectious HTLV-1 spread, particularly in the context of cell-to-cell transmission, a critical step in HTLV-1 transmission and pathogenesis. ..
Zhang W, Mendonça L, Mansky L. The Retrovirus Capsid Core. Subcell Biochem. 2018;88:169-187 pubmed publisher
..The physical and chemical properties of the capsid core that are critical to its functional role in reverse transcription and interaction with host cellular factors are highlighted to emphasize areas of current research. ..
Martin J, Maldonado J, MUELLER J, Zhang W, Mansky L. Molecular Studies of HTLV-1 Replication: An Update. Viruses. 2016;8: pubmed publisher
Zhang W, Kaufmann B, Chipman P, Kuhn R, Rossmann M. Membrane curvature in flaviviruses. J Struct Biol. 2013;183:86-94 pubmed publisher
..These results suggest that the organization of membrane proteins in small enveloped viruses mediate the formation of membrane curvature. ..
Maldonado J, Cao S, Zhang W, Mansky L. Distinct Morphology of Human T-Cell Leukemia Virus Type 1-Like Particles. Viruses. 2016;8: pubmed publisher
..The unique local flat Gag lattice morphological feature observed suggests that HTLV-1 Gag could be arranged in a lattice structure that is distinct from that of other retroviruses characterized to date. ..
Maldonado J, Angert I, Cao S, Berk S, Zhang W, MUELLER J, et al
. Perturbation of Human T-Cell Leukemia Virus Type 1 Particle Morphology by Differential Gag Co-Packaging. Viruses. 2017;9: pubmed publisher
..This information is useful for the quantitative analysis of Gag-Gag interactions that occur during virus particle assembly and in released immature particles. ..