Peilin Zhang

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression
    Peilin Zhang
    Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Biol Chem 285:9180-9. 2010
  2. pmc The functional genetic link of NLGN4X knockdown and neurodevelopment in neural stem cells
    Lingling Shi
    Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Hum Mol Genet 22:3749-60. 2013
  3. doi request reprint Comparison of reprogramming efficiency between transduction of reprogramming factors, cell-cell fusion, and cytoplast fusion
    Kouichi Hasegawa
    Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, University of Southern California, Los Angeles, California 90033, USA
    Stem Cells 28:1338-48. 2010
  4. pmc Regulation of Induced Pluripotent Stem (iPS) Cell Induction by Wnt/β-Catenin Signaling
    Peilin Zhang
    From the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033
    J Biol Chem 289:9221-32. 2014
  5. pmc Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models
    Liyun Zeng
    Zilhka Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
    PLoS ONE 8:e59685. 2013
  6. doi request reprint Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming
    Zong Wei
    Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Stem Cells 27:2969-78. 2009

Collaborators

Detail Information

Publications6

  1. pmc Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression
    Peilin Zhang
    Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Biol Chem 285:9180-9. 2010
    ..Taken together, these results demonstrate that Klf4 functions upstream of Nanog in ES cell self-renewal and in preventing ES cell differentiation...
  2. pmc The functional genetic link of NLGN4X knockdown and neurodevelopment in neural stem cells
    Lingling Shi
    Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Hum Mol Genet 22:3749-60. 2013
    ..Our functional genomics study highlights the utility of NSCs models in understanding the functional roles of CNVs in affecting neurodevelopment and conferring susceptibility to neurodevelopmental diseases. ..
  3. doi request reprint Comparison of reprogramming efficiency between transduction of reprogramming factors, cell-cell fusion, and cytoplast fusion
    Kouichi Hasegawa
    Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, University of Southern California, Los Angeles, California 90033, USA
    Stem Cells 28:1338-48. 2010
    ..The findings also suggest that the nucleus of the host pluripotent cell may contain components that accelerate the reprogramming process...
  4. pmc Regulation of Induced Pluripotent Stem (iPS) Cell Induction by Wnt/β-Catenin Signaling
    Peilin Zhang
    From the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033
    J Biol Chem 289:9221-32. 2014
    ..These studies reveal novel mechanisms underlying the regulation of reprogramming somatic cells to pluripotency by Wnt/β-catenin signaling. ..
  5. pmc Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models
    Liyun Zeng
    Zilhka Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
    PLoS ONE 8:e59685. 2013
    ..Our study highlights the utility of stem cell models in understanding the functional roles of copy number variations (CNVs) in conferring susceptibility to neurodevelopmental diseases...
  6. doi request reprint Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming
    Zong Wei
    Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Stem Cells 27:2969-78. 2009
    ..This study supports the idea that direct interactions between Klf4, Oct4, and Sox2 are critical for somatic cell reprogramming...