Lei Zhang

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer
    Lei Zhang
    School of Dentistry and Dental Research Institute, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 5:e15573. 2010
  2. ncbi Development of transcriptomic biomarker signature in human saliva to detect lung cancer
    Lei Zhang
    School of Dentistry and Dental Research Institute, University of California, Los Angeles, 90095, USA
    Cell Mol Life Sci 69:3341-50. 2012
  3. ncbi Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer
    Lei Zhang
    School of Dentistry and Dental Research Institute, University of California Los Angeles, Los Angeles, California 90095, USA
    Gastroenterology 138:949-57.e1-7. 2010
  4. ncbi Direct saliva transcriptome analysis
    Yu Hsiang Lee
    School of Dentistry and Dental Research Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Clin Chem 57:1295-302. 2011
  5. ncbi Proteomic analysis of human saliva from lung cancer patients using two-dimensional difference gel electrophoresis and mass spectrometry
    Hua Xiao
    Dental Research Institute, University of California, Los Angeles, Los Angeles, California 90095, USA
    Mol Cell Proteomics 11:M111.012112. 2012
  6. ncbi Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer
    Kai Gao
    School of Dentistry and Dental Research Institute, University of California Los Angeles, Los Angeles, CA, USA
    PLoS ONE 4:e5875. 2009
  7. ncbi Preclinical validation of salivary biomarkers for primary Sjögren's syndrome
    Shen Hu
    University of California, Los Angeles, USA
    Arthritis Care Res (Hoboken) 62:1633-8. 2010
  8. ncbi Electrochemical sensor for multiplex biomarkers detection
    Fang Wei
    Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, California, USA
    Clin Cancer Res 15:4446-52. 2009
  9. ncbi Salivary biomarkers for clinical applications
    Lei Zhang
    Dental Research Institute, School of Dentistry, University of California, Los Angeles, California, USA
    Mol Diagn Ther 13:245-59. 2009

Collaborators

Detail Information

Publications9

  1. ncbi Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer
    Lei Zhang
    School of Dentistry and Dental Research Institute, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 5:e15573. 2010
    ..In this study, a case-control discovery and independent preclinical validations were conducted to evaluate the performance and translational utilities of salivary transcriptomic and proteomic biomarkers for breast cancer detection...
  2. ncbi Development of transcriptomic biomarker signature in human saliva to detect lung cancer
    Lei Zhang
    School of Dentistry and Dental Research Institute, University of California, Los Angeles, 90095, USA
    Cell Mol Life Sci 69:3341-50. 2012
    ..These results poised the salivary biomarkers for the initiation of a multi-center validation in a definitive clinical context...
  3. ncbi Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer
    Lei Zhang
    School of Dentistry and Dental Research Institute, University of California Los Angeles, Los Angeles, California 90095, USA
    Gastroenterology 138:949-57.e1-7. 2010
    ....
  4. ncbi Direct saliva transcriptome analysis
    Yu Hsiang Lee
    School of Dentistry and Dental Research Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Clin Chem 57:1295-302. 2011
    ..We developed a streamlined, ambient-temperature processing, stabilization, and storage protocol for clinical analysis of salivary RNA...
  5. ncbi Proteomic analysis of human saliva from lung cancer patients using two-dimensional difference gel electrophoresis and mass spectrometry
    Hua Xiao
    Dental Research Institute, University of California, Los Angeles, Los Angeles, California 90095, USA
    Mol Cell Proteomics 11:M111.012112. 2012
    ..The discriminatory power of these candidate biomarkers indicate that a simple saliva test might be established for lung cancer clinical screening and detection...
  6. ncbi Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer
    Kai Gao
    School of Dentistry and Dental Research Institute, University of California Los Angeles, Los Angeles, CA, USA
    PLoS ONE 4:e5875. 2009
    ..Although the rationale for oral diseases applications (e.g. oral cancer) is intuitive, the rationale and relationship between systemic diseases and saliva biomarkers are unclear...
  7. ncbi Preclinical validation of salivary biomarkers for primary Sjögren's syndrome
    Shen Hu
    University of California, Los Angeles, USA
    Arthritis Care Res (Hoboken) 62:1633-8. 2010
    ..In the current study, we aimed to verify these candidate biomarkers in independent patient populations and to evaluate their predictive values for primary SS detection...
  8. ncbi Electrochemical sensor for multiplex biomarkers detection
    Fang Wei
    Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, California, USA
    Clin Cancer Res 15:4446-52. 2009
    ..Multiplexing assay of biomarkers at the point-of-care is an elusive goal for molecular diagnostics...
  9. ncbi Salivary biomarkers for clinical applications
    Lei Zhang
    Dental Research Institute, School of Dentistry, University of California, Los Angeles, California, USA
    Mol Diagn Ther 13:245-59. 2009
    ..This review presents current salivary biomarker research and technology developmental efforts for clinical applications...