L I Zhang

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Persistent and specific influences of early acoustic environments on primary auditory cortex
    L I Zhang
    Keck Center for Integrative Neurosciences, University of California at San Francisco, San Francisco, California 94143, USA
    Nat Neurosci 4:1123-30. 2001
  2. ncbi request reprint Topography and synaptic shaping of direction selectivity in primary auditory cortex
    Li I Zhang
    Coleman Memorial Laboratory and W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, California 94143, USA
    Nature 424:201-5. 2003
  3. pmc Disruption of primary auditory cortex by synchronous auditory inputs during a critical period
    Li I Zhang
    Keck Center of Integrative Neurosciences, University of California, San Francisco, CA 94143 0732, USA
    Proc Natl Acad Sci U S A 99:2309-14. 2002
  4. ncbi request reprint Emergence of input specificity of ltp during development of retinotectal connections in vivo
    H W Tao
    Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA
    Neuron 31:569-80. 2001
  5. ncbi request reprint Electrical activity and development of neural circuits
    L I Zhang
    Keck Center of Integrative Neuroscience, University of California, San Francisco, California 94143-0732, USA
    Nat Neurosci 4:1207-14. 2001
  6. pmc Suppression of cortical representation through backward conditioning
    Shaowen Bao
    Keck Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 100:1405-8. 2003
  7. ncbi request reprint Tone-evoked excitatory and inhibitory synaptic conductances of primary auditory cortex neurons
    Andrew Y Y Tan
    Coleman Memorial Laboratory and W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
    J Neurophysiol 92:630-43. 2004
  8. pmc Specialization of primary auditory cortex processing by sound exposure in the "critical period"
    Haruka Nakahara
    Keck Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:7170-4. 2004
  9. pmc Nonmonotonic synaptic excitation and imbalanced inhibition underlying cortical intensity tuning
    Guangying K Wu
    Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033, USA
    Neuron 52:705-15. 2006
  10. pmc Defining cortical frequency tuning with recurrent excitatory circuitry
    Bao Hua Liu
    Zilkha Neurogenetic Institute, University of Southern California, 1501 San Pablo Street, Los Angeles, California 90033, USA
    Nat Neurosci 10:1594-600. 2007

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Persistent and specific influences of early acoustic environments on primary auditory cortex
    L I Zhang
    Keck Center for Integrative Neurosciences, University of California at San Francisco, San Francisco, California 94143, USA
    Nat Neurosci 4:1123-30. 2001
    ..Thus, auditory experiences during early postnatal development are important in shaping the functional development of auditory cortical representations of specific acoustic environments...
  2. ncbi request reprint Topography and synaptic shaping of direction selectivity in primary auditory cortex
    Li I Zhang
    Coleman Memorial Laboratory and W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, California 94143, USA
    Nature 424:201-5. 2003
    ..The spectral asymmetry of the synaptic TRFs co-varied with CF, as had direction selectivity and sideband asymmetry, and thus suggested a synaptic mechanism for the shaping of FM direction selectivity and its topographic ordering...
  3. pmc Disruption of primary auditory cortex by synchronous auditory inputs during a critical period
    Li I Zhang
    Keck Center of Integrative Neurosciences, University of California, San Francisco, CA 94143 0732, USA
    Proc Natl Acad Sci U S A 99:2309-14. 2002
    ..Thus, patterned auditory inputs appear to play a crucial role in shaping neuronal processing/decoding circuits in the primary auditory cortex during a critical period...
  4. ncbi request reprint Emergence of input specificity of ltp during development of retinotectal connections in vivo
    H W Tao
    Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA
    Neuron 31:569-80. 2001
    ..Thus, input specificity of LTP emerges with neural development and depends on the pattern of synaptic activity...
  5. ncbi request reprint Electrical activity and development of neural circuits
    L I Zhang
    Keck Center of Integrative Neuroscience, University of California, San Francisco, California 94143-0732, USA
    Nat Neurosci 4:1207-14. 2001
    ..Selective findings discussed here illustrate some of our current understanding of the effects of electrical activity on circuit development and highlight areas that await further study...
  6. pmc Suppression of cortical representation through backward conditioning
    Shaowen Bao
    Keck Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 100:1405-8. 2003
    ....
  7. ncbi request reprint Tone-evoked excitatory and inhibitory synaptic conductances of primary auditory cortex neurons
    Andrew Y Y Tan
    Coleman Memorial Laboratory and W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
    J Neurophysiol 92:630-43. 2004
    ..Our data indicate that the interaction of synaptic excitation and inhibition shapes the time course and frequency tuning of the spike responses of AI neurons...
  8. pmc Specialization of primary auditory cortex processing by sound exposure in the "critical period"
    Haruka Nakahara
    Keck Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:7170-4. 2004
    ..These results show that the temporal order and pace of early, repetitive postnatal auditory inputs strongly affect the emergent and enduring functional organization of A1...
  9. pmc Nonmonotonic synaptic excitation and imbalanced inhibition underlying cortical intensity tuning
    Guangying K Wu
    Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033, USA
    Neuron 52:705-15. 2006
    ..Thus, cortical intensity tuning is primarily determined by excitatory inputs and shaped by cortical inhibition through a dynamic control of excitatory and inhibitory timing...
  10. pmc Defining cortical frequency tuning with recurrent excitatory circuitry
    Bao Hua Liu
    Zilkha Neurogenetic Institute, University of Southern California, 1501 San Pablo Street, Los Angeles, California 90033, USA
    Nat Neurosci 10:1594-600. 2007
    ..Thus, weakly tuned thalamocortical inputs determine the subthreshold responding range, whereas intracortical inputs largely define the tuning. Such circuits may ensure a faithful conveyance of sensory information...
  11. pmc Lateral sharpening of cortical frequency tuning by approximately balanced inhibition
    Guangying K Wu
    Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, Los Angeles, CA 90033, USA
    Neuron 58:132-43. 2008
    ....
  12. ncbi request reprint Moving visual stimuli rapidly induce direction sensitivity of developing tectal neurons
    Florian Engert
    Division of Neurobiology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Nature 419:470-5. 2002
    ..Thus, developing neural circuits can be modified rapidly and specifically by visual inputs of defined spatiotemporal patterns, in a manner consistent with predictions based on spike-time-dependent synaptic modification...
  13. pmc Heterosynaptic scaling of developing GABAergic synapses: dependence on glutamatergic input and developmental stage
    Yan Liu
    Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Neurosci 27:5301-12. 2007
    ..This mechanism may contribute to the formation of functional neural circuits with correlated excitatory and inhibitory inputs...