KUN contact ZHANG

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Library-free methylation sequencing with bisulfite padlock probes
    Dinh Diep
    Department of Bioengineering, University of California at San Diego, La Jolla, California, USA
    Nat Methods 9:270-2. 2012
  2. pmc Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming
    Sergio Ruiz
    Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Commun 4:1382. 2013
  3. pmc Genome-wide mapping of the sixth base
    Dinh Diep
    Department of Bioengineering, University of California at San Diego, 9500 Gilman Drive, MC0412, La Jolla, CA 92093 0412, USA
    Genome Biol 12:116. 2011
  4. pmc Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human
    Kun Zhang
    Department of Bioengineering, University of California at San Diego, La Jolla, California, USA
    Nat Methods 6:613-8. 2009
  5. pmc Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome
    Robert Shoemaker
    Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, California 92093, USA
    Genome Res 20:883-9. 2010
  6. pmc Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
    Jie Deng
    Department of Bioengineering, University of California San Diego, La Jolla, CA, USA
    Nat Biotechnol 27:353-60. 2009

Collaborators

Detail Information

Publications7

  1. pmc Library-free methylation sequencing with bisulfite padlock probes
    Dinh Diep
    Department of Bioengineering, University of California at San Diego, La Jolla, California, USA
    Nat Methods 9:270-2. 2012
    ....
  2. pmc Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming
    Sergio Ruiz
    Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Commun 4:1382. 2013
    ....
  3. pmc Genome-wide mapping of the sixth base
    Dinh Diep
    Department of Bioengineering, University of California at San Diego, 9500 Gilman Drive, MC0412, La Jolla, CA 92093 0412, USA
    Genome Biol 12:116. 2011
    ..Mapping of 5-hydroxylmethylcytosine in mammalian genomes has unveiled its unique role in the epigenetic regulation of gene expression...
  4. pmc Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human
    Kun Zhang
    Department of Bioengineering, University of California at San Diego, La Jolla, California, USA
    Nat Methods 6:613-8. 2009
    ..Comparison of expressed SNPs on the sense and antisense transcripts suggested that allelic ratios are primarily determined by cis-regulatory mechanisms on the sense transcripts...
  5. pmc Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome
    Robert Shoemaker
    Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, California 92093, USA
    Genome Res 20:883-9. 2010
    ..This study identified distinct types of ASM across many cell types and suggests a potential role for CpG-SNP in connecting genetic variation with the epigenome...
  6. pmc Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
    Jie Deng
    Department of Bioengineering, University of California San Diego, La Jolla, CA, USA
    Nat Biotechnol 27:353-60. 2009
    ..We found 288 regions methylated differently in fibroblasts and pluripotent cells. This targeted approach should be particularly useful for analyzing DNA methylation in large genomes...

Research Grants7

  1. Genome-scale anaylsis of DNA methylation in CpG Islands with bisulfite sequencing
    KUN contact ZHANG; Fiscal Year: 2010
    ..This enabling technology will help understand the functional roles of DNA methylation in gene regulation in various developmental processes and human diseases. ..
  2. Genome-scale anaylsis of DNA methylation in CpG Islands with bisulfite sequencing
    Kun Zhang; Fiscal Year: 2009
    ..This enabling technology will help understand the functional roles of DNA methylation in gene regulation in various developmental processes and human diseases. ..
  3. An Integrated lab-on-chip system for genome sequencing of single microbial cells
    KUN contact ZHANG; Fiscal Year: 2010
    ..Characterizing the genomic composition and structures of these microorganisms is a necessary step before their metabolic functions and the interactions with the host can be study in great detailed. ..
  4. Genome-scale anaylsis of DNA methylation in CpG Islands with bisulfite sequencing
    Kun Zhang; Fiscal Year: 2009
    ..This enabling technology will help understand the functional roles of DNA methylation in gene regulation in various developmental processes and human diseases. ..
  5. An Integrated lab-on-chip system for genome sequencing of single microbial cells
    Kun Zhang; Fiscal Year: 2009
    ..Characterizing the genomic composition and structures of these microorganisms is a necessary step before their metabolic functions and the interactions with the host can be study in great detailed. ..
  6. An Integrated lab-on-chip system for genome sequencing of single microbial cells
    Kun Zhang; Fiscal Year: 2009
    ..Characterizing the genomic composition and structures of these microorganisms is a necessary step before their metabolic functions and the interactions with the host can be study in great detailed. ..