Research Topics
Genomes and GenesSpecies | Jianhua ZhangSummaryAffiliation: University of Cincinnati Country: USA Publications
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Publications
Expression profiles of 109 apoptosis pathway-related genes in 82 mouse tissues and experimental conditionsJianhua Zhang
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Biochem Biophys Res Commun 297:537-44. 2002..This study provides valuable information on possible molecular mechanisms of differential apoptotic responses to developmental signals, environmental stimuli, and therapeutic treatments in tissue-specific manner...
Neural system-enriched gene expression: relationship to biological pathways and neurological diseasesJianhua Zhang
Department of Cell Biology, University of Cincinnati College of Medicine, Cincinnati 45267, USA
Physiol Genomics 18:167-83. 2004..Together, our data indicate the power of profiling an individual biologic system in a multisystem context to gain insight into the genomic basis of its structure and function...
Endonuclease G is required for early embryogenesis and normal apoptosis in miceJianhua Zhang
Department of Cell Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Proc Natl Acad Sci U S A 100:15782-7. 2003..These findings indicate that EndoG is essential during early embryogenesis and plays a critical role in normal apoptosis and nuclear DNA fragmentation...
Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptorsLu Zhang
Department of Cell Biology, Neurobiology, and Anatomy, University of Cincinnati Medical Center, Cincinnati, Ohio 45267, USA
J Neurosci 24:3344-54. 2004..These results suggest that the D1 and D3 receptors elicit opposite regulation of target gene expression by regulating ERK activation and c-fos induction after acute and chronic cocaine treatment...
Repeated cocaine administration induces gene expression changes through the dopamine D1 receptorsDongsheng Zhang
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0521, USA
Neuropsychopharmacology 30:1443-54. 2005....
c-fos modulates brain-derived neurotrophic factor mRNA expression in mouse hippocampal CA3 and dentate gyrus neuronsMei Dong
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Neurosci Lett 400:177-80. 2006..Our findings indicate that c-fos regulates expression of BDNF in distinct neuron populations of the hippocampal formation in vivo...
C-fos regulates neuropeptide Y expression in mouse dentate gyrusYongfei Wu
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Neurosci Lett 363:6-10. 2004..As NPY is an important endogenous anti-epileptic agent, our result is consistent with a hypothesis that the neuroprotective function of c-fos is mediated in part by regulation of NPY expression...
The dopamine D3 receptor antagonist NGB 2904 increases spontaneous and amphetamine-stimulated locomotionLaurel M Pritchard
Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
Pharmacol Biochem Behav 86:718-26. 2007..In combination, these data add to the behavioral profile of this novel D3 receptor ligand and provide further support for a role for dopamine D3 receptor inhibitory function in the modulation of rodent locomotion...
Role of endonuclease G in neuronal excitotoxicity in miceYongfei Wu
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, OH 45267, USA
Neurosci Lett 364:203-7. 2004..These results indicate that reduced expression of EndoG in the hippocampi of EndoG+/- mice leads to resistance to excitotoxicity...
Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypesYang Wang
Division of Nephrology, University of Cincinnati, Albert Sabin Way, Cincinnati, OH 45267 0585, USA
Nephrol Dial Transplant 23:525-33. 2008..The aim of this study was to develop and validate a pig model of AV fistula stenosis and then use it to dissect out the mechanisms responsible for this lesion...
The dopamine D1 receptor is a critical mediator for cocaine-induced gene expressionDongsheng Zhang
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati Medical Center, Cincinnati, Ohio 45267, USA
J Neurochem 82:1453-64. 2002..These results suggest that the D1 receptor is a critical mediator for cocaine-induced expression of these genes...
Dose-response analysis of locomotor activity and stereotypy in dopamine D3 receptor mutant mice following acute amphetamineRobert K McNamara
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
Synapse 60:399-405. 2006..0 and 10 mg/kg AMPH doses. These findings provide further support for an inhibitory role for the D3R in AMPH-induced locomotor activity, and demonstrate a more limited role for the D3R in modulating AMPH-induced stereotypy...
Deficient hippocampal c-fos expression results in reduced anxiety and altered response to chronic stress in female miceJill M Slane McQuade
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, OH 45267, USA
Neurosci Lett 403:125-30. 2006..These findings suggest that hippocampal c-fos plays a role in gender-dependent response to stress...
Systems biology of the autophagy-lysosomal pathwayAnil G Jegga
Division of Biomedical Informatics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
Autophagy 7:477-89. 2011....
Identification of chronic cocaine-induced gene expression through dopamine d1 receptors by using cDNA microarraysJianhua Zhang
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0521, USA
Ann N Y Acad Sci 965:1-9. 2002..Further studies are in progress to determine the physiological significance of the differential expression of these genes in chronic cocaine-induced behaviors...
DNA fragmentation factor 45 knockout mice exhibit longer memory retention in the novel object recognition task compared to wild-type miceJill M Slane McQuade
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0521, USA
Physiol Behav 76:315-20. 2002..These results suggest that a lack of DFF45 facilitates hippocampus-dependent nonspatial memory, as well as hippocampus-dependent spatial memory...
Generating gene knockout mice for studying mechanisms underlying drug addictionJianhua Zhang
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Methods Mol Med 79:351-63. 2003
Hemodynamic wall shear stress profiles influence the magnitude and pattern of stenosis in a pig AV fistulaMahesh K Krishnamoorthy
Cincinnati Dialysis Access Research Program, Department of Mechanical, Industrial, and Nuclear Engineering, University of Cincinnati, Cincinnati, Ohio 45267 0585, USA
Kidney Int 74:1410-9. 2008..These results suggest that fistula failure could be reduced by using computer modeling prior to surgical placement to alter the anatomical and, consequently, the wall shear stress profiles in an arteriovenous fistula...
Hippocampal expression of c-fos is not essential for spatial learningJianhua Zhang
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
Synapse 46:91-9. 2002..Our results suggest that hippocampal c-fos expression is not essential for spatial learning...
Neointimal hyperplasia in early arteriovenous fistula failurePrabir Roy-Chaudhury
Department of Medicine, Division of Nephrology, Cincinnati Dialysis Access Research Program, University of Cincinnati, Cincinnati, OH 45267 0585, USA
Am J Kidney Dis 50:782-90. 2007..Although inadequate dilatation of the venous segment was believed to have a role in early AVF failure, the exact pathogenesis of early AVF failure is unknown despite the magnitude of the clinical problem...
Cellular phenotypes in human stenotic lesions from haemodialysis vascular accessPrabir Roy-Chaudhury
Departments of Medicine, University of Cincinnati, OH, USA
Nephrol Dial Transplant 24:2786-91. 2009..The aim of the current study was to identify the specific cell types present within stenotic tissue samples from patients with AV fistula and graft failure...
Hemodialysis vascular access dysfunction: from pathophysiology to novel therapiesPrabir Roy-Chaudhury
University of Cincinatti Medical Center, Ohio 45267, USA
Blood Purif 21:99-110. 2003..Special emphasis is laid on the fact that PTFE dialysis access grafts could be the ideal clinical model for testing out novel local therapies to block neointimal hyperplasia...
Vascular access in hemodialysis: issues, management, and emerging conceptsPrabir Roy-Chaudhury
Division of Nephrology and Hypertension, University of Cincinnati Medical Center, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
Cardiol Clin 23:249-73. 2005..The possibility that dialysis access grafts and fistulae could be the ideal clinical model for testing novel local therapies to block neointimal hyperplasia is discussed...
Novel therapies for hemodialysis vascular access dysfunction: fact or fiction!Prabir Roy-Chaudhury
University of Cincinnati Medical Center, Cincinnati, Ohio, USA
Blood Purif 23:29-35. 2005..This is particularly unfortunate, since neointimal hyperplasia in the setting of hemodialysis vascular access fistulae and grafts could be the ideal clinical model to test novel therapeutic interventions for neointimal hyperplasia...
7-OH-DPAT and PD 128907 selectively activate the D3 dopamine receptor in a novel environmentLaurel M Pritchard
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati, OH, USA
Neuropsychopharmacology 28:100-7. 2003..Potential implications of these observations are discussed...
c-fos regulates neuronal excitability and survivalJianhua Zhang
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
Nat Genet 30:416-20. 2002..Our results suggest that c-fos is a genetic regulator for cellular mechanisms mediating neuronal excitability and survival...
Development of a local perivascular paclitaxel delivery system for hemodialysis vascular access dysfunction: polymer preparation and in vitro activityMurad Melhem
Department of Medicine, University of Cincinnati, Cincinnati, Ohio, USA
Blood Purif 24:289-98. 2006..We believe that these paclitaxel-loaded polymeric wraps could be ideally suited for perivascular drug delivery in the context of dialysis access grafts and fistulae...
Molecular genetic probing of dopamine receptors in drug addictionMing Xu
University of Cincinnati College of Medicine, Department of Cell Biology, Neurobiology and Anatomy, Cincinnati, OH 45267 0521, USA
Curr Opin Drug Discov Devel 7:703-8. 2004..These studies will provide new insights for improved therapeutic strategies for the prevention and treatment of drug addiction...
Perivascular paclitaxel wraps block arteriovenous graft stenosis in a pig modelBurnett Kelly
Department of Surgery, Industrial and Nuclear Engineering, University of Cincinnati, Cincinnati, OH 45267-0585, USA
Nephrol Dial Transplant 21:2425-31. 2006..It is likely that this novel approach could result in a significant reduction in the huge economic and health morbidity costs currently associated with this recalcitrant clinical problem...
Expression of the rat CYP2A3 gene in transgenic miceTing Su
Wadsworth Center, New York State Department of Health and School of Public Health, State University of New York at Albany, Albany, New York 12201-0509, USA
Drug Metab Dispos 30:548-52. 2002..Furthermore, the levels of CYP2A3 mRNA were very low in all lines examined, suggesting that more distal regulatory regions may be involved in the abundant expression of the CYP2A genes in the olfactory mucosa...
The graft response to transplantation: a gene expression profile analysisKenneth Christopher
Laboratory of Molecular Immunology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Physiol Genomics 15:52-64. 2003..Post-transplant, a shift was noted in genes classified as defense, communication, and metabolism. Our results identify novel components of the graft response to transplantation injury and rejection...
Lack of self-administration of cocaine in dopamine D1 receptor knock-out miceS Barak Caine
Alcohol and Drug Abuse Research Center, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA
J Neurosci 27:13140-50. 2007..We conclude that D1 receptor knock-out mice do not reliably self-administer cocaine and that the D1 receptor is critical for the reinforcing effects of cocaine and other dopamine agonists, but not food or opioids, in mice...
Function of gamma-aminobutyric acid receptor/channel rho 1 subunits in spinal cordWei Zheng
Division of Molecular Medicine, Harbor UCLA Medical Center, The David Geffen School of Medicine University of California Los Angeles, Torrance, California 90502, USA
J Biol Chem 278:48321-9. 2003..These findings indicate that the GABA receptor/channel rho 1 subunit plays an important role in modulating spinal cord pain transmission functions in vivo...
Murine hepatitis virus strain 1 produces a clinically relevant model of severe acute respiratory syndrome in A/J miceNadine De Albuquerque
Toronto General Hospital, 585 University Ave, NCSB-11-1236, Toronto, Ontario M5G 2N2, Canada
J Virol 80:10382-94. 2006..This study describes a potentially useful small animal model of human SARS, defines its pathogenesis, and suggests treatment strategies...
Effects of acute "binge" cocaine on mRNA levels of mu opioid receptor and neuropeptides in dopamine D1 or D3 receptor knockout miceYan Zhou
The Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, New York 10021, USA
Synapse 61:50-9. 2007....
Altered distributions of nucleocytoplasmic transport-related proteins in the spinal cord of a mouse model of amyotrophic lateral sclerosisJianhua Zhang
Department of Neurology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, Osaka, 570-8507, Japan
Acta Neuropathol (Berl) 112:673-80. 2006..This is the first report investigating nucleocytoplasmic transport in the ALS model mouse, and our present results imply that its dysfunction could be involved in the pathomechanisms underlying ALS...
Opposite regulation of cocaine-induced intracellular signaling and gene expression by dopamine D1 and D3 receptorsJianhua Zhang
Department of Anesthesia and Critical Care, The University of Chicago, Chicago, IL 60637, USA
Ann N Y Acad Sci 1074:1-12. 2006..Lastly, such regulation requires proper ERK activation. These results suggest that D1 and D3 receptors oppositely regulate target gene expression by regulating ERK activation after cocaine administration...
c-Fos facilitates the acquisition and extinction of cocaine-induced persistent changesJianhua Zhang
Division of Neuropathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
J Neurosci 26:13287-96. 2006..Our findings indicate that c-Fos produced in D1 receptor-expressing neurons integrates mechanisms to facilitate both the acquisition and extinction of cocaine-induced persistent changes...
Kainic acid induces early and transient autophagic stress in mouse hippocampusJohn J Shacka
Division of Neuropathology, Department of Pathology, University of Alabama at Birmingham, SC 961, 1530 3rd Ave S, Birmingham, AL 35294 0017, USA
Neurosci Lett 414:57-60. 2007..Together these data indicate the transient induction of autophagic stress by KA which may serve to regulate excitotoxic death in mouse hippocampus...
Deficiency of DNA fragmentation factor 45 results in reduced oocyte apoptosis in response to doxorubicinMei Dong
Cell Res 17:735-6. 2007
Dopamine D(1) and D(3) receptors oppositely regulate NMDA- and cocaine-induced MAPK signaling via NMDA receptor phosphorylationHongyuan Jiao
Department of Anesthesia and Critical Care, University of Chicago, Chicago, Illinois, USA
J Neurochem 103:840-8. 2007..These results suggest that dopamine D(1) and D(3) receptors oppositely regulate NMDA- and cocaine-induced MAPK signaling via phosphorylation of NR1...
Enhanced radiation-induced cytotoxic effect by 2-ME in glioma cells is mediated by induction of cell cycle arrest and DNA damage via activation of ATM pathwaysHuichao Zou
The 1st Affiliated Hospital of Harbin Medical University, No 23 Youzheng Street, Nangang District, Harbin, Heilongjiang Province, China
Brain Res 1185:231-8. 2007..These results suggest that 2-ME enhancement of the sensitivity of glioma cell lines to radiotherapy is mediated by induction of G2/M cell cycle arrest and increased DNA damage via activation of ATM kinases...
Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemiaJayne M Ness
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
J Neurosci Res 86:1115-24. 2008..The differential expression of c-Fos in HI-resistant hippocampal subpopulations vs. cleaved caspase-3 in dying neurons suggests a neuroprotective role for c-Fos expression in neonatal HI...
Rac1 GTPase is activated by hepatitis B virus replication--involvement of HBXTuan Lin Tan
School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, 637459 Singapore
Biochim Biophys Acta 1783:360-74. 2008..HBV may possibly make use of an activated Rac1 signaling pathway for increased replication and resultant metastatic effects...
Comparative proteomics analysis of vascular smooth muscle cells incubated with S- and R-enantiomers of atenolol using iTRAQ-coupled two-dimensional LC-MS/MSJianjun Sui
School of Chemical and Biomedical Engineering, College of Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore
Mol Cell Proteomics 7:1007-18. 2008..Our preliminary results thus provide molecular evidence on the metabolic effect and possible link of calcium-binding proteins with treatment of hypertension associated with atenolol...
Nitric oxide activation of Erk1/2 regulates the stability and translation of mRNA transcripts containing CU-rich elementsShuibang Wang
Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
Nucleic Acids Res 34:3044-56. 2006..Over-expression of hnRNP K, like NO*, repressed translation of CURE-containing mRNA. These findings define a sequence-specific mechanism of NO*-triggered gene regulation that stabilizes mRNA, but represses translation...
Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragmentsTorstein Tengs
Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Nucleic Acids Res 32:e121. 2004..Here, we show that the RECORD libraries may be used for digital karyotyping and for pathogen identification by computational subtraction...
Activities of key enzymes in sucrose-to-starch conversion in wheat grains subjected to water deficit during grain fillingJianchang Yang
College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China 225009
Plant Physiol 135:1621-9. 2004....
Effects of nicotine preexposure on sulpiride-induced dopamine release in the nucleus accumbensShafiqur Rahman
Smoking and Nicotine Dependence Research, Centre for Addiction and Mental Health, and Department of Psychiatry, University of Toronto, Toronto, ON, Canada
Eur J Pharmacol 494:31-4. 2004..The reduction of sulpiride-induced nucleus accumbens dopamine release after nicotine treatment is likely the result of down-regulation of somatodendritic dopamine autoreceptors...
Characterization of stem cell factor gene-modified human natural killer cell line, NK-92 cells: implication in NK cell-based adoptive cellular immunotherapyJian Zhang
School of Life Sciences, University of Science and Technology of China, Hefei City, Anhui 230027, PR China
Oncol Rep 11:1097-106. 2004..SCF gene-modified NK-92 cells (NK92-SCF cells) are more promising than their parent cells for adoptive cellular immunotherapy...
Pharmacological manipulations of the pedunculopontine tegmental nucleus in the rat reduce self-administration of both nicotine and cocaineWilliam A Corrigall
Department of Physiology, University of Toronto, Toronto, Ontario, Canada
Psychopharmacology (Berl) 160:198-205. 2002..The direct action of nicotine in PPTg may be through GABAergic mechanisms that have been shown to influence nicotine self-administration preferentially compared to cocaine...
BACE1 (beta-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over timeYi Luo
Amgen Inc, Thousand Oaks, CA, USA
Neurobiol Dis 14:81-8. 2003..These data provide evidence that neither beta-secretase nor Abeta plays a vital role in mouse physiology and that chronic beta-secretase inhibition could be a useful approach in treating AD...
Cardiopulmonary sympathetic and vagal afferents excite C1-C2 propriospinal cells in ratsJianhua Zhang
Department of Physiology, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA
Brain Res 969:53-8. 2003..Results are consistent with the hypothesis that CPSA input can be processed in C1-C2 segments to produce neural modulation in distant spinal segments...
Differential effects of urinary bladder distension on high cervical projection neurons in primatesMargaret J Chandler
Department of Physiology, BMSB 653, University of Oklahoma Health Sciences Center, PO Box 26901, Oklahoma City, OK 73190, USA
Brain Res 949:97-104. 2002..Furthermore, results of this study indicated that effects of sensory inputs on spinal neurons might vary depending on axonal projections of the neurons examined...
Protease-activated receptor-2 (PAR-2) expression in human fibroblasts is regulated by growth factors and extracellular matrixBarry L Gruber
Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA
J Invest Dermatol 123:832-9. 2004..Results indicate that the degree of fibroblast proliferation, attenuated by extracellular matrix and upregulated by growth factors, influences whether fibroblasts express PAR-2 and, thus, would be responsive to protease signaling...
Identification of a region in the vitamin D-binding protein that mediates its C5a chemotactic cofactor functionJianhua Zhang
Department of Pathology, Stony Brook University School of Medicine, Stony Brook, NY 11794 8691, USA
J Biol Chem 279:53282-7. 2004....
Erythropoietin prevents the acute myocardial inflammatory response induced by ischemia/reperfusion via induction of AP-1Tao Rui
Vascular Cell Biology Laboratory, Lawson Health Research Institute, University of Western Ontario, London, ON, Canada N6A 4G5
Cardiovasc Res 65:719-27. 2005..This beneficial effect of EPO is mediated by eNOS-derived NO via a PI3-kinase-dependent activation of AP-1...
Living with genome instability: the adaptation of phytoplasmas to diverse environments of their insect and plant hostsXiaodong Bai
Department of Entomology, The Ohio State University, Ohio Agricultural Research and Development Center, Wooster, 44691, USA
J Bacteriol 188:3682-96. 2006..The AY-WB genome is approximately 154 kb smaller than the OY-M genome, primarily as a result of fewer multicopy sequences, including PMUs. Furthermore, AY-WB lacks genes that are truncated and are part of incomplete pathways in OY-M...
Mitogen-activated protein kinase is involved in abscisic acid-induced antioxidant defense and acts downstream of reactive oxygen species production in leaves of maize plantsAying Zhang
College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, People's Republic of China
Plant Physiol 141:475-87. 2006..ABA-induced H(2)O(2) production activates MAPK, which in turn induces the expression and the activities of antioxidant enzymes. The activation of MAPK also enhances the H(2)O(2) production, forming a positive feedback loop...
Recombinant human prolactin protects against irradiation-induced myelosuppressionWei Ci Zhang
Institute of Immunopharmacology and Immunotherapy, Shandong University, 44 Wenhua West Road, Jinan 250021, China
Cell Mol Immunol 2:379-85. 2005..It was concluded that rhPRL might act on erythropoiesis and could be a potential candidate for the treatment of irradiation-induced myelosuppresion in clinic...
cGMP-independent nitric oxide signaling and regulation of the cell cycleXiaolin Cui
Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
BMC Genomics 6:151. 2005..Bt2cAMP was used to block signaling attributable to NO*-induced decreases in cAMP...
Human prolactin improves engraftment and reconstitution of human peripheral blood lymphocytes in SCID miceRui Sun
School of Pharmacy, Shandong University, Jinan 250012, China
Cell Mol Immunol 1:129-36. 2004..Thus, rhPRL stimulation promotes reconstitution of human immune system in huPBL-SCID mice...
Effects of gene tranfection with CH50 polypeptide on the invasion ability of bladder cancer cell line BIU-87Zhuang Wu
Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
J Huazhong Univ Sci Technolog Med Sci 25:320-2, 338. 2005..05). It was concluded that CH50 polypeptide was successfully expressed in BIU-87 cells by gene transfection, by which the in vitro invasion ability of BIU-87 was inhibited...
Selective interaction of nitric oxide synthase inhibition with phencyclidine: behavioural and NMDA receptor binding studies in the ratDaniel Klamer
Department of Pharmacology, , , P.O. Box 431, , Sweden
Behav Brain Res 159:95-103. 2005..These results suggest that the NO-sensitive effects of PCP are not sufficiently explained by its antagonistic effect at the NMDA receptor channel complex...
[Genetic polymorphism of two STR loci D2S1399 and D5S2500 in Eastern Chinese Han population]Shui-xiu Xia
Department of Forensic Medicine, Medical School of Soochow University, Suzhou 215007, China
Fa Yi Xue Za Zhi 20:200-1, 204. 2004..745 and 0.807, 0.958 and 0.917, 0.554 and 0.643, respectively. CONCLUSION: The result showed that D2S1399 and D5S2500 were highly informative loci and suitable for forensic application...
Spinal inhibitory effects of cardiopulmonary afferent inputs in monkeys: neuronal processing in high cervical segmentsMargaret J Chandler
Department of Physiology, University of Oklahoma Health Sciences Center, PO Box 26901, Oklahoma City, OK 73190, USA
J Neurophysiol 87:1290-302. 2002..Results of these studies were consistent with the idea that modulation of spinal nociceptive transmission might involve neuronal connections in high cervical segments...
