Jian Ying Zhang

Summary

Affiliation: University of Texas at El Paso
Country: USA

Publications

  1. ncbi request reprint Autoantibody responses in Chinese hepatocellular carcinoma
    Jian Ying Zhang
    W M Keck Autoimmune Disease Center, Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, 92037, USA
    J Clin Immunol 22:98-105. 2002
  2. ncbi request reprint Preferential humoral immune response in prostate cancer to cellular proteins p90 and p62 in a panel of tumor-associated antigens
    Fu Dong Shi
    Department of Molecular and Experimental Medicine, W M Keck Autoimmune Disease Center, The Scripps Research Institute, La Jolla, California, USA
    Prostate 63:252-8. 2005
  3. ncbi request reprint Significance of autoantibodies against insulin-like growth factor II mRNA-binding proteins in patients with hepatocellular carcinoma
    Takashi Himoto
    W M Keck Autoimmune Disease Center, Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
    Int J Oncol 26:311-7. 2005
  4. ncbi request reprint Analyses of autoantibodies against tumor-associated antigens in patients with hepatocellular carcinoma
    Takashi Himoto
    W M Keck Autoimmune Disease Center, Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
    Int J Oncol 27:1079-85. 2005
  5. pmc Using proteomic approach to identify tumor-associated antigens as markers in hepatocellular carcinoma
    Kok Sun Looi
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    J Proteome Res 7:4004-12. 2008
  6. pmc Autoantibodies against glucose-regulated protein 78 as serological diagnostic biomarkers in hepatocellular carcinoma
    Qing Shao
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    Int J Oncol 41:1061-7. 2012
  7. pmc Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma
    Pengfei Ren
    Henan Key Laboratory of Tumor Epidemiology and College of Public Health, Zhengzhou University, Zhengzhou, Henan 450052, P R China
    Oncol Rep 30:2297-303. 2013
  8. pmc Serum peptidome patterns of hepatocellular carcinoma based on magnetic bead separation and mass spectrometry analysis
    Xia Ying
    Department of Medical Oncology, The First Affiliated Hospital of Xi an Jiaotong University, Xi an, Shannxi, PR China
    Diagn Pathol 8:130. 2013
  9. pmc Autoantibodies to tumor-associated antigens as biomarkers in human hepatocellular carcinoma (HCC)
    Liping Dai
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    Exp Hematol Oncol 2:15. 2013
  10. ncbi request reprint Tumor-associated antigen arrays to enhance antibody detection for cancer diagnosis
    Jian Ying Zhang
    Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, Texas 79968, USA
    Cancer Detect Prev 28:114-8. 2004

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Autoantibody responses in Chinese hepatocellular carcinoma
    Jian Ying Zhang
    W M Keck Autoimmune Disease Center, Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, 92037, USA
    J Clin Immunol 22:98-105. 2002
    ....
  2. ncbi request reprint Preferential humoral immune response in prostate cancer to cellular proteins p90 and p62 in a panel of tumor-associated antigens
    Fu Dong Shi
    Department of Molecular and Experimental Medicine, W M Keck Autoimmune Disease Center, The Scripps Research Institute, La Jolla, California, USA
    Prostate 63:252-8. 2005
    ..Cytoplasmic p90 autoantigen was recently cloned from a cDNA expression library using serum antibody from a cancer patient. The humoral immune response to p90 in prostate cancer and benign prostatic hyperplasia (BPH) was examined...
  3. ncbi request reprint Significance of autoantibodies against insulin-like growth factor II mRNA-binding proteins in patients with hepatocellular carcinoma
    Takashi Himoto
    W M Keck Autoimmune Disease Center, Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
    Int J Oncol 26:311-7. 2005
    ....
  4. ncbi request reprint Analyses of autoantibodies against tumor-associated antigens in patients with hepatocellular carcinoma
    Takashi Himoto
    W M Keck Autoimmune Disease Center, Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
    Int J Oncol 27:1079-85. 2005
    ....
  5. pmc Using proteomic approach to identify tumor-associated antigens as markers in hepatocellular carcinoma
    Kok Sun Looi
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    J Proteome Res 7:4004-12. 2008
    ....
  6. pmc Autoantibodies against glucose-regulated protein 78 as serological diagnostic biomarkers in hepatocellular carcinoma
    Qing Shao
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    Int J Oncol 41:1061-7. 2012
    ..4%. Our data indicate that anti-GRP78 autoantibodies may be potential diagnostic markers for HCC, especially in conjunction with AFP...
  7. pmc Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma
    Pengfei Ren
    Henan Key Laboratory of Tumor Epidemiology and College of Public Health, Zhengzhou University, Zhengzhou, Henan 450052, P R China
    Oncol Rep 30:2297-303. 2013
    ..05). The data indicate that Prdx1 may contribute to malignant transformation of the esophagus, and may be used as a biomarker in the immunodiagnosis of ESCC. ..
  8. pmc Serum peptidome patterns of hepatocellular carcinoma based on magnetic bead separation and mass spectrometry analysis
    Xia Ying
    Department of Medical Oncology, The First Affiliated Hospital of Xi an Jiaotong University, Xi an, Shannxi, PR China
    Diagn Pathol 8:130. 2013
    ..The purpose of the study is to discover specific low molecular weight (LMW) serum peptidome biomarkers and establish a diagnostic pattern for HCC...
  9. pmc Autoantibodies to tumor-associated antigens as biomarkers in human hepatocellular carcinoma (HCC)
    Liping Dai
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    Exp Hematol Oncol 2:15. 2013
    ..In this review, we will focus on the important features of TAA and the possibility that autoantibodies to TAAs can be used as biomarkers in immunodiagnosis and prognosis of HCC...
  10. ncbi request reprint Tumor-associated antigen arrays to enhance antibody detection for cancer diagnosis
    Jian Ying Zhang
    Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, Texas 79968, USA
    Cancer Detect Prev 28:114-8. 2004
    ..It is conceivable that autoantibody profiles involving different panels or arrays of TAAs might be developed in the future and the results could be useful for cancer diagnosis...
  11. pmc Mini-array of multiple tumor-associated antigens to enhance autoantibody detection for immunodiagnosis of hepatocellular carcinoma
    Jian Ying Zhang
    Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, Texas 79968, USA
    Autoimmun Rev 6:143-8. 2007
    ..It also suggested that different types of cancer might require different panels of TAAs to achieve the sensitivity and specificity required to make immunodiagnosis a feasible adjunct to tumor diagnosis...
  12. pmc Autoantibodies to tumor-associated antigens as diagnostic biomarkers in hepatocellular carcinoma and other solid tumors
    Jian Ying Zhang
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    Expert Rev Mol Diagn 10:321-8. 2010
    ..The present review will focus on the recent advances in our studies primarily associated with the idea and possibility that autoantibodies to TAAs can be used as biomarkers in immunodiagnosis of HCC and other solid tumors...
  13. pmc Antibody detection using tumor-associated antigen mini-array in immunodiagnosing human hepatocellular carcinoma
    Jian Ying Zhang
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX, USA
    J Hepatol 46:107-14. 2007
    ..The panel of eight TAAs includes Imp1, p62, Koc, p53, c-myc, cyclin B1, survivin and p16 full-length recombinant proteins...
  14. ncbi request reprint Humoral immune response to p16, a cyclin-dependent kinase inhibitor in human malignancies
    Koksun Looi
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    Oncol Rep 16:1105-10. 2006
    ..It is conceivable that auto-antibody profiles involving different panels or arrays of TAAs might be developed in the future and the results could be useful for cancer diagnosis...
  15. pmc Autoantibodies to tumor-associated antigens combined with abnormal alpha-fetoprotein enhance immunodiagnosis of hepatocellular carcinoma
    Yao Chen
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    Cancer Lett 289:32-9. 2010
    ..2% to 88.7%. AFP and anti-TAA were independent markers and the simultaneous use of these two markers significantly resulted in the increased sensitivity of HCC detection...
  16. ncbi request reprint Autoimmune response to anti-apoptotic protein survivin and its association with antibodies to p53 and c-myc in cancer detection
    Roxanne Megliorino
    Department of Biological Sciences, The University of Texas, El Paso, TX, USA
    Cancer Detect Prev 29:241-8. 2005
    ..3% (149/546) for the total group of cancer patients. It became apparent from our data that the combination of antibodies might acquire higher sensitivity...
  17. ncbi request reprint Using immunomic approach to enhance tumor-associated autoantibody detection in diagnosis of hepatocellular carcinoma
    Liping Dai
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    Clin Immunol 152:127-39. 2014
    ....
  18. pmc Using immunoproteomics to identify tumor-associated antigens (TAAs) as biomarkers in cancer immunodiagnosis
    Qing Zhu
    Department of Medical Oncology, The First Affiliated Hospital of Xi an Jiao Tong University Medical Center, Xi an, Shaanxi, China Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, USA Electronic address
    Autoimmun Rev 12:1123-8. 2013
    ..This review will mainly focus on the recent advances in our studies using immunoproteomic approach to identify and characterize TAAs as biomarkers in cancer. ..
  19. pmc Using immunoproteomics to identify alpha-enolase as an autoantigen in liver fibrosis
    Bo Peng
    Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, El Paso, Texas 79968, United States
    J Proteome Res 12:1789-96. 2013
    ..3%, 12/84), as well as in sera from healthy individuals (4.1%, 3/74). Therefore, alpha-enolase is an autoantigen that elicits autoimmune response in liver fibrosis and can be a potential prognostic factor for liver fibrosis diagnosis. ..
  20. ncbi request reprint Autoantibodies to Ca2+ binding protein Calnuc is a potential marker in colon cancer detection
    Yao Chen
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX, USA
    Int J Oncol 30:1137-44. 2007
    ..1%). This indicates that a mini-array of multiple TAAs which includes Calnuc might provide a novel non-invasive approach to enhance antibody detection for colon cancer diagnosis...
  21. pmc Identification of tumor-associated antigens as diagnostic and predictive biomarkers in cancer
    Jian Ying Zhang
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX, USA
    Methods Mol Biol 520:1-10. 2009
    ....
  22. pmc Humoral autoimmune responses to insulin-like growth factor II mRNA-binding proteins IMP1 and p62/IMP2 in ovarian cancer
    Xinxin Liu
    Center for Tumor Biotherapy, The First Affiliated Hospital and College of Public Health, Zhengzhou University, Zhengzhou, Henan 450052, China Department of Biological Sciences and Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA
    J Immunol Res 2014:326593. 2014
    ..01). Our preliminary data suggest that IMP1 and p62/IMP2 can stimulate autoimmune responses in ovarian cancer, and anti-IMP1 and anti-p62/IMP2 autoantibodies could be used as potential biomarkers in immunodiagnosis of ovarian cancer...
  23. pmc Preferential autoimmune response in prostate cancer to cyclin B1 in a panel of tumor-associated antigens
    Liping Dai
    Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    J Immunol Res 2014:827827. 2014
    ..This study further supports the hypothesis that a customized TAA array can be used for enhancing anti-TAA autoantibody detection, and it may constitute a promising and powerful tool for immunodiagnosis of PCa. ..
  24. pmc Autoantibody response to murine double minute 2 protein in immunodiagnosis of hepatocellular carcinoma
    Mei Liu
    Beijing You An Hospital, Capital Medical University, Beijing 10069, China Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA
    J Immunol Res 2014:906532. 2014
    ..Our preliminary data indicate that MDM2 and anti-MDM2 system may be a potential biomarker for early stage HCC screening and immunodiagnosis. ..
  25. ncbi request reprint Enhancement of antibody detection in cancer using panel of recombinant tumor-associated antigens
    Jian Ying Zhang
    W M Keck Autoimmune Disease Center, The Scripps Research Institute, La Jolla, California 92037, USA
    Cancer Epidemiol Biomarkers Prev 12:136-43. 2003
    ....
  26. ncbi request reprint Recursive partitioning as an approach to selection of immune markers for tumor diagnosis
    James A Koziol
    Division of Biomathematics, The Scripps Research Institute, La Jolla, California 92037, USA
    Clin Cancer Res 9:5120-6. 2003
    ..We used recursive partitioning to assess whether we could accurately classify individuals as either cancer patients or normals on the basis of the profile of antibody reactivity to the seven TAAs for each individual...
  27. ncbi request reprint Cyclin B1 is commonly expressed in the cytoplasm of primary human acute myelogenous leukemia cells and serves as a leukemia-associated antigen associated with autoantibody response in a subset of patients
    Elisabeth Ersvaer
    Institute of Medicine, University of Bergen, Bergen, Norway
    Eur J Haematol 79:210-25. 2007
    ..We therefore investigated (i) whether a similar expression pattern could be detected in native human acute myelogenous leukemia (AML) cells and (ii) whether cyclin B1 specific antibodies could be detected in AML...
  28. ncbi request reprint A comparison of treatment combinations with and without radiotherapy for hepatocellular carcinoma with portal vein and/or inferior vena cava tumor thrombus
    Zhao Chong Zeng
    Radiation Oncology, Fudan University, Zhongshan Hospital, Shanghai 200032, China
    Int J Radiat Oncol Biol Phys 61:432-43. 2005
    ..To evaluate the potential role of external beam radiation therapy (EBRT) in the treatment of patients with hepatocellular carcinoma (HCC) who have portal vein (PV) and/or inferior vena cava (IVC) tumor thrombi...
  29. ncbi request reprint Radiation therapy for adrenal gland metastases from hepatocellular carcinoma
    Zhao Chong Zeng
    Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Jpn J Clin Oncol 35:61-7. 2005
    ..External beam radiation therapy has seldom been applied for patients with adrenal gland metastases...