Hong Jie Zhang

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. doi request reprint Lamiridosins, hepatitis C virus entry inhibitors from Lamium album
    Hongjie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Illinois 60612, USA
    J Nat Prod 72:2158-62. 2009
  2. ncbi request reprint Miliusanes, a class of cytotoxic agents from Miliusa sinensis
    Hong Jie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Illinois 60612, USA
    J Med Chem 49:693-708. 2006
  3. ncbi request reprint Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata
    Hong Jie Zhang
    Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, Chicago, IL, USA
    Planta Med 71:452-7. 2005
  4. ncbi request reprint Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea
    Hong Jie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Nat Prod 66:263-8. 2003
  5. ncbi request reprint New Sesquiterpenes from Litsea verticillata
    Hong Jie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences m c877, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 S Wood Street, 60612, USA
    J Nat Prod 66:609-15. 2003
  6. ncbi request reprint Natural anti-HIV agents-part I: (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata
    Vu Dinh Hoang
    Program for Collaborative Research in Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 S Wood St, Chicago, IL 60612, USA
    Phytochemistry 59:325-9. 2002
  7. ncbi request reprint Bioactive constituents from Asparagus cochinchinensis
    Hong Jie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy M C877, College of Pharmacy, The University of Illinois at Chicago, 833 S Wood Street, Chicago, Illinois 60612, USA
    J Nat Prod 67:194-200. 2004
  8. ncbi request reprint Rourinoside and rouremin, antimalarial constituents from Rourea minor
    Zhen dan He
    Program for Collaborative Research in the Pharmaceutical Sciences, M C 781, Department of Medical Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, 833 S Wood Street, Chicago, IL 60612, USA
    Phytochemistry 67:1378-84. 2006
  9. ncbi request reprint Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva
    Hong Jie Zhang
    Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Planta Med 68:1088-91. 2002
  10. ncbi request reprint Antimalarial constituents from Nauclea orientalis (L.) L
    Zhen dan He
    Program for Collaborative Research in Pharmaceutical Sciences, M C 781, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, 833 S Wood Street, Chicago, Illinois 60612, USA
    Chem Biodivers 2:1378-86. 2005

Collaborators

  • Harry H S Fong
  • John M Pezzuto
  • Nguyen Manh Cuong
  • Zeynep Aydogmus
  • Djaja Doel Soejarto
  • Wei Xiang
  • Guido F Pauli
  • Yang Lu
  • A D Mesecar
  • Sheng Hong Li
  • Ghee Teng Tan
  • Cui Ying Ma
  • Sudarat Homhual
  • Cuiying Ma
  • Zhen dan He
  • Xue Mei Niu
  • Han Dong Sun
  • Kongmany Sydara
  • Bounhoong Southavong
  • Nguyen Van Hung
  • Ping Yao
  • Somsanith Bouamanivong
  • Nuntavan Bunyapraphatsara
  • Angkana Herunsalee
  • Wongsatit Chaukul
  • Pamela Tamez
  • Vu Dinh Hoang
  • Sebisubi Fred Musoke
  • Tamara P Kondratyuk
  • Bernard D Santarsiero
  • Tamara Kondratyuk
  • S Bouamanivong
  • Yuehong Wang
  • Ryan J Case
  • Scott G Franzblau
  • Jia Wang
  • Qi Tai Zheng
  • Peng Cao
  • Ma Lin Li
  • Qin E Tian
  • Yun Heng Shen
  • Li Yan Peng
  • Pamela A Tamez

Detail Information

Publications24

  1. doi request reprint Lamiridosins, hepatitis C virus entry inhibitors from Lamium album
    Hongjie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Illinois 60612, USA
    J Nat Prod 72:2158-62. 2009
    ....
  2. ncbi request reprint Miliusanes, a class of cytotoxic agents from Miliusa sinensis
    Hong Jie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Illinois 60612, USA
    J Med Chem 49:693-708. 2006
    ..The absolute stereochemistry of miliusanes was established by the Mosher ester method. Forty-two modified miliusane derivatives were also prepared and evaluated for their cytotoxic activities...
  3. ncbi request reprint Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata
    Hong Jie Zhang
    Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, Chicago, IL, USA
    Planta Med 71:452-7. 2005
    ..R5) with IC50 values of 38.1, 54.6, 91.0, 9.9, 40.3, 129.8, and 122.7 microM, respectively. Structure elucidation and identification were based on spectroscopic means including 1D and 2D NMR analyses...
  4. ncbi request reprint Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea
    Hong Jie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Nat Prod 66:263-8. 2003
    ..5 microgram/mL (15.3 microM; selective index = 1.4). The structures of these isolates were determined by spectral data including 1D and 2D NMR spectra...
  5. ncbi request reprint New Sesquiterpenes from Litsea verticillata
    Hong Jie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences m c877, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 S Wood Street, 60612, USA
    J Nat Prod 66:609-15. 2003
    ..5 (27.5), 17.4 (73.1), and 28.0 (119.7) microg/mL (microM), respectively. The structures of these isolates were determined by spectral data including 1D and 2D NMR spectra. Compound 11 was confirmed by X-ray crystallographic analysis...
  6. ncbi request reprint Natural anti-HIV agents-part I: (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata
    Vu Dinh Hoang
    Program for Collaborative Research in Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 S Wood St, Chicago, IL 60612, USA
    Phytochemistry 59:325-9. 2002
    ..7 microM) while being devoid of cytotoxicity at 20 microg/ml. The structures were elucidated by 1D and 2D NMR spectroscopy, and the absolute configuration of the new sesquiterpenoid was determined by the generation of Mosher esters...
  7. ncbi request reprint Bioactive constituents from Asparagus cochinchinensis
    Hong Jie Zhang
    Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy M C877, College of Pharmacy, The University of Illinois at Chicago, 833 S Wood Street, Chicago, Illinois 60612, USA
    J Nat Prod 67:194-200. 2004
    ..The structures were determined by spectroscopic and chemical methods...
  8. ncbi request reprint Rourinoside and rouremin, antimalarial constituents from Rourea minor
    Zhen dan He
    Program for Collaborative Research in the Pharmaceutical Sciences, M C 781, Department of Medical Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, 833 S Wood Street, Chicago, IL 60612, USA
    Phytochemistry 67:1378-84. 2006
    ..Compounds 1-3 showed weak in vitro activities against Plasmodium falciparum. Their structures and stereochemistry were elucidated by spectroscopic methods and selected enzyme hydrolysis...
  9. ncbi request reprint Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva
    Hong Jie Zhang
    Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Planta Med 68:1088-91. 2002
    ..Verrucarin L acetate and roridin E were characterized as macrocyclic trichothecene sesquiterpenoids and found to inhibit the growth of Plasmodium falciparum with IC 50 values below 1 ng/ml...
  10. ncbi request reprint Antimalarial constituents from Nauclea orientalis (L.) L
    Zhen dan He
    Program for Collaborative Research in Pharmaceutical Sciences, M C 781, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, 833 S Wood Street, Chicago, Illinois 60612, USA
    Chem Biodivers 2:1378-86. 2005
    ..Compounds 1, 2, 6, and 8 showed moderate in vitro activities against Plasmodium falciparum. Their structures and configurations were elucidated by spectroscopic methods including 1D- and 2D-NMR analyses...
  11. doi request reprint Study of antimalarial activity of chemical constituents from Diospyros quaesita
    Cui Ying Ma
    Program for Collaborative Research in the Pharmaceutical Sciences, M C 781, Department of Medical Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 S Wood Street, Chicago, Illinois 60612, USA
    Chem Biodivers 5:2442-8. 2008
    ..The structure of 2 was elucidated based on spectroscopic data analysis including 1D- and 2D-NMR, and HR-ESI-MS...
  12. pmc Anti-tuberculosis constituents from the stem bark of Micromelum hirsutum
    Cuiying Ma
    Program for Collaborative Research in the Pharmaceutical Sciences, M C 781, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, 833 S Wood Street, Chicago, IL 60612, USA
    Planta Med 71:261-7. 2005
    ..3 microg/mL, while compounds 4 and 5 were considered inactive (MIC > 128 microg/mL). Structure elucidation and identification were based on spectroscopic analysis, including MS, 1D/2D NMR, and a full (1)H spin system analysis of 1...
  13. ncbi request reprint Antimalarial compounds from Grewia bilamellata
    Cuiying Ma
    Program for Collaborative Research in Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    J Nat Prod 69:346-50. 2006
    ..The structures of 1-3 were elucidated and identified on the basis of spectroscopic data including 1D and 2D NMR analysis...
  14. doi request reprint Antimicrobial anthraquinones from Morinda angustifolia
    Wei Xiang
    Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla, Yunnan 666303, PR China
    Fitoterapia 79:501-4. 2008
    ..The new compound demonstrated significant antimicrobial activity against Bacillus subtilis, Escherichia coli, Micrococcus luteus, Sarcina lutea, Candida albicans and Saccharomyces sake...
  15. ncbi request reprint "Studies on biodiversity of Vietnam and Laos" 1998-2005: examining the impact
    Djaja Doel Soejarto
    Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    J Nat Prod 69:473-81. 2006
    ..Highlights are presented and the significance is discussed...
  16. ncbi request reprint ent-Kaurane diterpenoids from the leaves of Isodon xerophilus
    Sheng Hong Li
    State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, The Chinese Academy of Sciences, Heilongtan, Kunming, Yunnan, P R China
    Planta Med 68:946-8. 2002
    ..Compound 6 demonstrated most potent cytotoxic activity against K562 and T24 human tumor cell lines with IC(50) = 0.09 and 0.32 microg/ml, respectively...
  17. ncbi request reprint Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza
    Sudarat Homhual
    Department of Pharmacognosy, Faculty of Pharmacy Mahidol University, Bangkok, Thailand
    Planta Med 72:255-60. 2006
    ..1 microM. The structures of these isolates were determined by spectral data, and that of compound 1 was confirmed by X-ray crystallographic analysis...
  18. ncbi request reprint Four new prenylated isoflavonoids in Tadehagi triquetrum
    Wei Xiang
    State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204 Yunnan, People s Republic of China
    J Agric Food Chem 53:267-71. 2005
    ..The structures of 1-4 were elucidated on the basis of spectroscopic and spectrometric methods. Compounds 1-3 displayed mild anthelminthic bioactivity, and compound 3 showed a significant binding ability to the estrogen receptor...
  19. ncbi request reprint Bioactive dammarane triterpenes from the mangrove plant Bruguiera gymnorrhiza
    Sudarat Homhual
    Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
    J Nat Prod 69:421-4. 2006
    ..4 microM and selectively inhibited cyclooxygenase-2 (COX-2) activity with an IC(50) value of 0.37 microM. Compounds 2 and 3 were not active in these bioassays...
  20. ncbi request reprint Constituents of Gnetum montanum
    Wei Xiang
    Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming 650204, PR China
    Fitoterapia 73:40-2. 2002
    ..The structure of 1 was determined to be 2-(5'-methoxy-3'-hydroxyphenyl)-4-hydroxybenzofuran on the basis of spectroscopic evidence...
  21. ncbi request reprint Maoecrystal V, cytotoxic diterpenoid with a novel C19 skeleton from Isodon eriocalyx (Dunn.) hara
    Sheng Hong Li
    Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, P R China
    Org Lett 6:4327-30. 2004
    ..Compound 1 showed remarkable inhibitory activity toward HeLa cells with IC(50) = 0.02 microg/mL (cis-platin: IC(50) = 0.99 microg/mL)...
  22. ncbi request reprint ent-Kaurene diterpenoids from Isodon oresbius
    Wei Xiang
    State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China
    Phytochemistry 65:1173-7. 2004
    ..Their structures were determined by spectroscopic means. Compound 12 showed inhibitory activity toward K562 cells with IC(50)=1.43 microg/ml...
  23. ncbi request reprint Taxuyunnanines S-V, new taxoids from Taxus yunnanensis
    Sheng Hong Li
    Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming, Yunnan, China
    Planta Med 68:253-7. 2002
    ..Taxuyunnanine S (1), is the most hydroxylated abeotaxoid discovered to date from Taxus species. The structures were determined by spectroscopic means including 1D and 2D NMR experiments...
  24. ncbi request reprint Chemical constituents from Amentotaxus yunnanensis and Torreyayunnanensis
    Sheng Hong Li
    State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming 650204, Yunnan, People s Republic of China
    J Nat Prod 66:1002-5. 2003
    ..yunnanensis and T. yunnanensis suggests that these two genera are closely related. The identification and structural elucidation of these isolates were based on spectral data analysis including 1D and 2D NMR...