Xianquan Zhan

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. ncbi A reference map of a human pituitary adenoma proteome
    Xianquan Zhan
    The Charles B. Stout Neuroscience Mass Spectrometry Laboratory, The University of Tennessee Health Science Center Memphis, TN 38163, USA
    Proteomics 3:699-713. 2003
  2. ncbi Novel molecular signaling and classification of human clinically nonfunctional pituitary adenomas identified by gene expression profiling and proteomic analyses
    Carlos S Moreno
    Department of Pathology and Laboratory Medicine and Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 65:10214-22. 2005
  3. ncbi Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry
    Xianquan Zhan
    Charles B Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Anal Biochem 354:279-89. 2006
  4. ncbi Mass spectrometric identification of in vivo nitrotyrosine sites in the human pituitary tumor proteome
    Xianquan Zhan
    Department of Neurology, University of Tennessee Health Science Center, Memphis, TN, USA
    Methods Mol Biol 566:137-63. 2009
  5. ncbi Differences in the spatial and quantitative reproducibility between two second-dimensional gel electrophoresis systems
    Xianquan Zhan
    The Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, 847 Monroe Avenue, Room 117, Memphis, TN 38163, USA
    Electrophoresis 24:1834-46. 2003
  6. ncbi Comparative proteomics analysis of human pituitary adenomas: current status and future perspectives
    Xianquan Zhan
    Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Mass Spectrom Rev 24:783-813. 2005
  7. ncbi Signaling pathway networks mined from human pituitary adenoma proteomics data
    Xianquan Zhan
    University of Tennessee Health Science Center, Memphis, USA
    BMC Med Genomics 3:13. 2010
  8. ncbi Proteomics analysis of growth hormone isoforms in the human pituitary
    Xianquan Zhan
    Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Proteomics 5:1228-41. 2005
  9. ncbi The human pituitary nitroproteome: detection of nitrotyrosyl-proteins with two-dimensional Western blotting, and amino acid sequence determination with mass spectrometry
    Xianquan Zhan
    Charles B Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, 847 Monroe Avenue, Room 117, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 325:1180-6. 2004
  10. ncbi Proteomics and transcriptomics analyses of secretagogin down-regulation in human non-functional pituitary adenomas
    Xianquan Zhan
    Charles B Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, 847 Monroe Avenue, Room 117, Memphis, TN 38163, USA
    Pituitary 6:189-202. 2003

Collaborators

  • D M Desiderio
  • Carlos S Moreno
  • Chheng Orn Evans
  • Nelson M Oyesiku
  • Chheng-Orn Evans
  • Cui Li
  • Paula M Vertino
  • Michael T McCabe
  • Mammerhi Okor
  • Zhiqiang Xiao
  • Songping Liang
  • Xiaoying Wu
  • Feng Li
  • Ping Chen
  • Jianling Li
  • Maoyu Li
  • Jingyun Xie
  • Xueping Feng
  • Zhuchu Chen

Detail Information

Publications15

  1. ncbi A reference map of a human pituitary adenoma proteome
    Xianquan Zhan
    The Charles B. Stout Neuroscience Mass Spectrometry Laboratory, The University of Tennessee Health Science Center Memphis, TN 38163, USA
    Proteomics 3:699-713. 2003
    ..These data will be used to expand the proteome database of the human pituitary, which can be accessed in the website http://www.utmem.edu /proteomics...
  2. ncbi Novel molecular signaling and classification of human clinically nonfunctional pituitary adenomas identified by gene expression profiling and proteomic analyses
    Carlos S Moreno
    Department of Pathology and Laboratory Medicine and Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 65:10214-22. 2005
    ....
  3. ncbi Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry
    Xianquan Zhan
    Charles B Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Anal Biochem 354:279-89. 2006
    ..Those data indicate that protein nitration might be an important molecular event in the formation of a human pituitary nonfunctional adenoma...
  4. ncbi Mass spectrometric identification of in vivo nitrotyrosine sites in the human pituitary tumor proteome
    Xianquan Zhan
    Department of Neurology, University of Tennessee Health Science Center, Memphis, TN, USA
    Methods Mol Biol 566:137-63. 2009
    ..Bioinformatics tools are then used to correlate nitrotyrosine sites with a functional domain/motif in order to understand the relationship between tyrosine nitration and the structural/functions of proteins...
  5. ncbi Differences in the spatial and quantitative reproducibility between two second-dimensional gel electrophoresis systems
    Xianquan Zhan
    The Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, 847 Monroe Avenue, Room 117, Memphis, TN 38163, USA
    Electrophoresis 24:1834-46. 2003
    ....
  6. ncbi Comparative proteomics analysis of human pituitary adenomas: current status and future perspectives
    Xianquan Zhan
    Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Mass Spectrom Rev 24:783-813. 2005
    ..The methodologies that are used in comparative proteomics studies of human pituitary adenomas are readily exportable to other different areas of cancer research...
  7. ncbi Signaling pathway networks mined from human pituitary adenoma proteomics data
    Xianquan Zhan
    University of Tennessee Health Science Center, Memphis, USA
    BMC Med Genomics 3:13. 2010
    ..Here, we describe the significant signaling pathway networks that were mined from human pituitary adenoma proteomic data with the Ingenuity pathway analysis system...
  8. ncbi Proteomics analysis of growth hormone isoforms in the human pituitary
    Xianquan Zhan
    Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Proteomics 5:1228-41. 2005
    ..These results provide novel clues for further studies of the functions, and mechanisms of action, of hGH in the human pituitary and in growth hormone-related diseases...
  9. ncbi The human pituitary nitroproteome: detection of nitrotyrosyl-proteins with two-dimensional Western blotting, and amino acid sequence determination with mass spectrometry
    Xianquan Zhan
    Charles B Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, 847 Monroe Avenue, Room 117, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 325:1180-6. 2004
    ..Those nitrotyrosyl-proteins participate in neurotransmission, cellular immunity, and cellular structure and mobility...
  10. ncbi Proteomics and transcriptomics analyses of secretagogin down-regulation in human non-functional pituitary adenomas
    Xianquan Zhan
    Charles B Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Health Science Center, 847 Monroe Avenue, Room 117, Memphis, TN 38163, USA
    Pituitary 6:189-202. 2003
    ..This novel finding may provide clues to clarify the basic molecular mechanisms of pituitary adenoma formation, and to identify new tumor-related markers...
  11. ncbi Heterogeneity analysis of the human pituitary proteome
    Xianquan Zhan
    The Charles B. Stout Neuroscience Mass Spectrometry Laboratory and the Department of Neurology, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Clin Chem 49:1740-51. 2003
    ..CONCLUSIONS: A heterogeneity exists in the human pituitary proteome as a function of gender, age, and race. These findings will serve as a basis for our comparative proteomics studies of human pituitary adenomas...
  12. ncbi Spot volume vs. amount of protein loaded onto a gel: a detailed, statistical comparison of two gel electrophoresis systems
    Xianquan Zhan
    Charles B. Stout Neuroscience Mass Spectrometry Laboratory, Department of Neurology, University of Tennessee Health Science Center, 847 Monroe Avenue, Memphis, TN 38163, USA
    Electrophoresis 24:1818-33. 2003
    ..The results demonstrated that the Dodeca gel system provides a wider linear dynamic range to measure the changes in the protein abundance in pituitary proteome...
  13. ncbi Targets of tyrosine nitration in diabetic rat retina
    Xianquan Zhan
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Mol Cell Proteomics 7:864-74. 2008
    ..The present results provide new insights regarding tyrosine nitration and its potential role in the molecular mechanisms of diabetic retinopathy...
  14. ncbi Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses
    Chheng Orn Evans
    Department of Neurosurgery and Laboratory of Molecular Neurosurgery and Biotechnology, Emory University School of Medicine, 1365 B Clifton Rd, NE, Suite 6200, Atlanta, GA, 30322, USA
    Pituitary 11:231-45. 2008
    ..In the current era of molecular medicine, these findings greatly enhance our understanding and supercede immunohistochemical diagnosis...
  15. ncbi Proteomic comparison of two-dimensional gel electrophoresis profiles from human lung squamous carcinoma and normal bronchial epithelial tissues
    Cui Li
    Genomics Proteomics Bioinformatics 1:58-67. 2003
    ..These data will be used to establish human lung cancer proteome database to further study human lung squamous carcinoma...