H Zhai

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Reactions of non-immunologic contact urticaria on scalp, face, and back
    Hongbo Zhai
    Department of Dermatology, University of California, San Francisco, California 94143 0989, USA
    Skin Res Technol 18:436-41. 2012
  2. doi request reprint Allergic contact dermatitis: effect of age
    Hongbo Zhai
    Department of Dermatology, School of Medicine, University of California San Francisco, CA, USA
    Cutan Ocul Toxicol 31:20-5. 2012
  3. doi request reprint Determination of the antioxidative capacity of an antioxidant complex and idebenone: an in vitro rapid and sensitive method
    Hongbo Zhai
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143 0989, USA
    J Cosmet Dermatol 7:96-100. 2008
  4. doi request reprint Skin decontamination of glyphosate from human skin in vitro
    H Zhai
    Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, 90 Medical Center Way, San Francisco, CA 94143 0989, USA
    Food Chem Toxicol 46:2258-60. 2008
  5. ncbi request reprint Tape-stripping method in man: comparison of evaporimetric methods
    Hongbo Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco, CA 94143 0989, USA
    Skin Res Technol 13:207-10. 2007
  6. ncbi request reprint Protection from irritants
    Hongbo Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco, CA 94143 0989, USA
    Curr Probl Dermatol 34:47-57. 2007
  7. ncbi request reprint In vitro model for decontamination of human skin: formaldehyde
    H Zhai
    Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, 90 Medical Center Way, San Francisco, CA 94143 0989, USA
    Food Chem Toxicol 45:618-21. 2007
  8. ncbi request reprint Evaluating skin-protective materials against contact irritants and allergens. An in vivo screening human model
    H Zhai
    Department of Dermatology, University of California, School of Medicine 94143 0989, USA
    Contact Dermatitis 38:155-8. 1998
  9. ncbi request reprint Putative skin-protective formulations in preventing and/or inhibiting experimentally-produced irritant and allergic contact dermatitis
    H Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco 94143 0989, USA
    Contact Dermatitis 41:190-2. 1999
  10. ncbi request reprint Evaluation of the antioxidant capacity and preventive effects of a topical emulsion and its vehicle control on the skin response to UV exposure
    H Zhai
    Department of Dermatology, School of Medicine, University of California, San Francisco, 94143, USA
    Skin Pharmacol Physiol 18:288-93. 2005

Collaborators

Detail Information

Publications29

  1. doi request reprint Reactions of non-immunologic contact urticaria on scalp, face, and back
    Hongbo Zhai
    Department of Dermatology, University of California, San Francisco, California 94143 0989, USA
    Skin Res Technol 18:436-41. 2012
    ..This study compared the reactivity of scalp, face, and back to nonimmunologic contact urticants (NICU) to ascertain relative responsiveness...
  2. doi request reprint Allergic contact dermatitis: effect of age
    Hongbo Zhai
    Department of Dermatology, School of Medicine, University of California San Francisco, CA, USA
    Cutan Ocul Toxicol 31:20-5. 2012
    ....
  3. doi request reprint Determination of the antioxidative capacity of an antioxidant complex and idebenone: an in vitro rapid and sensitive method
    Hongbo Zhai
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143 0989, USA
    J Cosmet Dermatol 7:96-100. 2008
    ....
  4. doi request reprint Skin decontamination of glyphosate from human skin in vitro
    H Zhai
    Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, 90 Medical Center Way, San Francisco, CA 94143 0989, USA
    Food Chem Toxicol 46:2258-60. 2008
    ..This in vitro model is not only economic and rapid, but also provides quantitative data that may aid screening for optimal decontaminants...
  5. ncbi request reprint Tape-stripping method in man: comparison of evaporimetric methods
    Hongbo Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco, CA 94143 0989, USA
    Skin Res Technol 13:207-10. 2007
    ..This study compares the sensitivity and correlation of open and closed chamber devices in a tape-stripping human model. The amount of tape removed SC was also quantified with a protein assay method...
  6. ncbi request reprint Protection from irritants
    Hongbo Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco, CA 94143 0989, USA
    Curr Probl Dermatol 34:47-57. 2007
    ..Additionally, careful selection of appropriate skin protection products in the specific situations/environments is suggested...
  7. ncbi request reprint In vitro model for decontamination of human skin: formaldehyde
    H Zhai
    Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, 90 Medical Center Way, San Francisco, CA 94143 0989, USA
    Food Chem Toxicol 45:618-21. 2007
    ..However, results from this model need validation in vivo. The model may provide a facile and robust method of accelerating knowledge of decontamination mechanism and lead to enhanced efficacy...
  8. ncbi request reprint Evaluating skin-protective materials against contact irritants and allergens. An in vivo screening human model
    H Zhai
    Department of Dermatology, University of California, School of Medicine 94143 0989, USA
    Contact Dermatitis 38:155-8. 1998
    ..01) decreasing Rhus allergic contact dermatitis. This model, provides an easy approach to screening protectants. Its clinical significance requires comparison with an open rather than an occluded challenge...
  9. ncbi request reprint Putative skin-protective formulations in preventing and/or inhibiting experimentally-produced irritant and allergic contact dermatitis
    H Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco 94143 0989, USA
    Contact Dermatitis 41:190-2. 1999
    ..Paraffin wax in cetyl alcohol was quantitatively the most effective formulation. These results suggest that some formulations may provide protective effects against certain, but not all, irritants or allergens...
  10. ncbi request reprint Evaluation of the antioxidant capacity and preventive effects of a topical emulsion and its vehicle control on the skin response to UV exposure
    H Zhai
    Department of Dermatology, School of Medicine, University of California, San Francisco, 94143, USA
    Skin Pharmacol Physiol 18:288-93. 2005
    ..Vitamin E emulsion and its vehicle control proved effective in preventing induction of erythema and reducing inflammatory damage caused by UV exposure. The effect of vitamin E emulsion exceeded that of an 'active control'...
  11. ncbi request reprint Cutaneous bioassay of salicylic acid as a keratolytic
    S J Bashir
    Department of Dermatology, University of California, 90 Medical Center Way, Surge Building 110, P O Box 0989, San Francisco, CA 94143 0989, USA
    Int J Pharm 292:187-94. 2005
    ..This indicates that the quest to increase the amount of free, non-dissociated SA is, in fact, counterproductive as the more acidic preparations resulted in skin irritation and barrier disruption...
  12. ncbi request reprint Human in vivo and in vitro hydroquinone topical bioavailability, metabolism, and disposition
    R C Wester
    Department of Dermatology, University of California, San Francisco 94143 0989, USA
    J Toxicol Environ Health A 54:301-17. 1998
    ..Risk assessment should not only involve the bioavailability of intact topical hydroquinone, but also consider phase I and phase II metabolism in both humans and any animal for which toxicity potential was assessed...
  13. ncbi request reprint Efficacy of corticosteroids in acute experimental irritant contact dermatitis?
    C Levin
    Department of Dermatology, University of California at San Francisco Medical Center, CA 94143 0989, USA
    Skin Res Technol 7:214-8. 2001
    ..However, their clinical efficacy remains sub judice. This study was designed to assess the efficacy of low- and medium-potency corticosteroids on irritant dermatitis...
  14. ncbi request reprint Skin occlusion and irritant and allergic contact dermatitis: an overview
    H Zhai
    Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, San Francisco, CA 94143-0989, USA
    Contact Dermatitis 44:201-6. 2001
    ..This overview summarizes the adverse effects of occlusion...
  15. ncbi request reprint Hydrating effects of a corticoid oil formulation and its vehicle on human skin
    H Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco, Calif 94143 0989, USA
    Skin Pharmacol Appl Skin Physiol 16:367-71. 2003
    ..The results support intuitive dermatologic judgment of advising patients to apply moisturizing medicaments after bathing...
  16. ncbi request reprint Percutaneous penetration enhancers: an overview
    H Y Thong
    Department of Dermatology, School of Medicine, University of California, San Francisco, CA 94143 0989, USA
    Skin Pharmacol Physiol 20:272-82. 2007
    ....
  17. ncbi request reprint A rapid, accurate, and facile method to quantify the antioxidative capacity of topical formulations
    Hongbo Zhai
    Department of Dermatology, University of California San Francisco, CA 94143 0989, USA
    Skin Res Technol 9:254-6. 2003
    ..A simple, rapid and accurate method is demanded. This study examined the antioxidative status of a pH balanced vitamin E containing formulation versus its vehicle control utilizing a photochemiluminescence device...
  18. ncbi request reprint Long-term repetitive sodium lauryl sulfate-induced irritation of the skin: an in vivo study
    Nara Branco
    Department of Dermatology, University of California, School of Medicine, San Francisco, CA 94143 0989, USA
    Contact Dermatitis 53:278-84. 2005
    ..Alternative models should be developed to prove or disprove the accommodation hypothesis...
  19. ncbi request reprint Provocative use test of nickel coins in nickel-sensitized subjects and controls
    H Zhai
    Department of Dermatology, University of California, School of Medicine, Surge 110, Box 0989, San Francisco, CA 94143 0989, USA
    Br J Dermatol 149:311-7. 2003
    ..g. watches). The clinical relevance of nickel-containing coins eliciting nickel dermatitis associated with extensive occupational exposure (e.g. coins handled by cashiers) has not been determined...
  20. ncbi request reprint Effects of skin occlusion on percutaneous absorption: an overview
    H Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco, Calif 94143-0989, USA
    Skin Pharmacol Appl Skin Physiol 14:1-10. 2001
    ..It often, but not always, increases percutaneous absorption of applied chemicals. This overview focuses on the effect of skin occlusion on percutaneous absorption...
  21. ncbi request reprint Comparative evaporimetry in man
    Jigna H Shah
    Department of Dermatology, University of California, San Francisco, CA 94143 0989, USA
    Skin Res Technol 11:205-8. 2005
    ..This study compares this commercial instrument, a closed chamber device, with a traditional open-chamber device...
  22. ncbi request reprint Clinical microneedle injection of methyl nicotinate: stratum corneum penetration
    Raja K Sivamani
    Department of Bioengineering, University of California, Berkeley, CA, USA
    Skin Res Technol 11:152-6. 2005
    ..In this work, we compare microneedle injections with topical application (TA) to investigate if microneedles enhance in vivo drug delivery past the stratum corneum...
  23. doi request reprint Tape stripping on a human nail: quantification of removal
    E Tudela
    Department of Dermatology, University of California San Francisco, San Francisco, CA 9143 0989, USA
    Skin Res Technol 14:472-7. 2008
    ..Tape stripping is commonly used to investigate the stratum corneum (SC). This study assesses if protein quantitative tape stripping method was suitable for human nails...
  24. doi request reprint Tissue viability imaging: mapping skin erythema
    Hongbo Zhai
    Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA
    Skin Res Technol 15:14-9. 2009
    ..Before TiVi can be effectively used in studies of diseased or damaged skin, the variability in normal skin red blood cell concentration (RBC(conc)) requires evaluation...
  25. doi request reprint Comparison of tissue viability imaging and colorimetry: skin blanching
    Hongbo Zhai
    Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA
    Skin Res Technol 15:20-3. 2009
    ....
  26. ncbi request reprint Human scalp irritation compared to that of the arm and back
    Hongbo Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco, CA 94143 0989, USA
    Contact Dermatitis 51:196-200. 2004
    ..Thus, these data support the current standard skin-compatibility testing procedure, employing the back for potential irritation testing of hair care products...
  27. doi request reprint Measuring human skin buffering capacity: an in vitro model
    Hongbo Zhai
    Department of Dermatology, School of Medicine, University of California, San Francisco, CA 94143 0989, USA
    Skin Res Technol 15:470-5. 2009
    ..It has been thought that skin possesses buffering capacity. This study measured the skin buffering capacity against two model solutions of acid and base at three concentrations with an in vitro system...
  28. ncbi request reprint Hydration vs. skin permeability to nicotinates in man
    Hongbo Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco 94143 0989, USA
    Skin Res Technol 8:13-8. 2002
    ....
  29. ncbi request reprint Occlusion vs. skin barrier function
    Hongbo Zhai
    Department of Dermatology, University of California, School of Medicine, San Francisco 94143 0989, USA
    Skin Res Technol 8:1-6. 2002
    ..It also obstructs the normal ventilation of the skin surface and increases stratum corneum hydration and hence compromises skin barrier function...