Research Topics
| T A ZesiewiczSummaryAffiliation: University of South Florida Country: USA Publications
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Publications
Depression in Parkinson's diseaseTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida College of Medicine, 4 Columbia Drive, Suite 410, Tampa, FL 33606, USA
Curr Psychiatry Rep 4:69-73. 2002..This information may help guide clinical treatment and define the need for further studies...
A pilot, double-blind, placebo-controlled trial of pregabalin (Lyrica) in the treatment of essential tremorTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida, Tampa, Florida 33612, USA
Mov Disord 22:1660-3. 2007..PGB provided significant improvements in accelerometry and in action tremor limb scores on the FTM. However, larger studies are needed to further evaluate the potential effect of PGB on ET...
A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3T A Zesiewicz
Department of Neurology, Ataxia Research Center, University of South Florida, Tampa, USA
Neurology 78:545-50. 2012....
Treatment of imbalance with varenicline Chantix(R): report of a patient with fragile X tremor/ataxia syndromeT A Zesiewicz
Parkinson Research Foundation Center of Excellence at University of South Florida, University of South Florida, Tampa, FL 34677, USA
Acta Neurol Scand 119:135-8. 2009..Varenicline was started as part of a smoking cessation program...
Subjective improvement in proprioception in 2 patients with atypical Friedreich ataxia treated with varenicline (Chantix)Theresa A Zesiewicz
Department of Neurology, University of South Florida Ataxia Research Center, Tampa, FL 33612, USA
J Clin Neuromuscul Dis 10:191-3. 2009....
Potential influences of complementary therapy on motor and non-motor complications in Parkinson's diseaseTheresa A Zesiewicz
Department of Neurology, University of South Florida, Tampa, 33612, USA
CNS Drugs 23:817-35. 2009..Whenever possible, clinicians should ensure that complementary therapy is used appropriately in PD patients without reducing the benefits of dopaminergic therapy...
Nonmotor symptoms of Parkinson's diseaseTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center and Department of Neurology, University of South Florida, 12901 Bruce B Downs Blvd, MDC Box 55, Tampa, FL 33612, USA
Expert Rev Neurother 6:1811-22. 2006..A new screening questionnaire and the revised Unified PD Rating Scale should assist healthcare providers to better identify and evaluate these symptoms. This article reviews the identification and treatment of nonmotor symptoms in PD...
Levodopa-induced dyskinesia in Parkinson's disease: epidemiology, etiology, and treatmentTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida, Tampa, Florida 33612, USA
Curr Neurol Neurosci Rep 7:302-10. 2007..Deep brain stimulation of the subthalamic nucleus is now the most commonly used surgical procedure for PD patients, and it is very effective in treating LID...
Drug-induced hyperkinetic movement disorders by nonneuroleptic agentsTheresa A Zesiewicz
Department of Neurology, University of South Florida, Tampa 33612, USA
Handb Clin Neurol 100:347-63. 2011..Most information regarding drug-induced hyperkinetic disorders comes from case reports and anecdotes, rather than controlled clinical trials. Further research with larger controlled trials needs to verify many of these findings...
Evidence-based guideline update: treatment of essential tremor: report of the Quality Standards subcommittee of the American Academy of NeurologyT A Zesiewicz
University of South Florida, Tampa, USA
Neurology 77:1752-5. 2011..This evidence-based guideline is an update of the 2005 American Academy of Neurology practice parameter on the treatment of essential tremor (ET)...
Practice Parameter: treatment of nonmotor symptoms of Parkinson disease: report of the Quality Standards Subcommittee of the American Academy of NeurologyT A Zesiewicz
University of South Florida, Tampa, USA
Neurology 74:924-31. 2010..Articles pertaining to cognitive and mood dysfunction in PD, as well as treatment of sialorrhea with botulinum toxin, were previously reviewed as part of American Academy of Neurology practice parameters and were not included here...
Placebo-controlled trial of lubiprostone for constipation associated with Parkinson diseaseW G Ondo
Department of Neurology, University of Texas Health Science Center, Houston, TX, USA
Neurology 78:1650-4. 2012..To evaluate the efficacy and tolerability of lubiprostone (Amitiza) for constipation in Parkinson disease (PD) in a double-blind, randomized, controlled study...
Driving safety in Parkinson's diseaseT A Zesiewicz
Department of Neurology, University of South Florida, Tampa, USA
Neurology 59:1787-8. 2002..7, p < 0.01). In PD patients, collisions were associated with Hoehn and Yahr stage (chi(2) = 12.4, p = 0.006) and correlated with Unified Parkinson's Disease Rating Scale score (r = 0.5, p < 0.01)...
Reduction of circulating endothelial cells in peripheral blood of ALS patientsSvitlana Garbuzova-Davis
Center of Excellence for Aging and Brain Repair, College of Medicine, University of South Florida, Tampa, Florida, United States of America
PLoS ONE 5:e10614. 2010..Since circulating endothelial cells (CECs) in the peripheral blood are associated with endothelium damage, being detached dysfunctional endothelial cells, we hypothesized that CEC levels may reflect endothelium condition in ALS patients...
Open-label pilot study of levetiracetam (Keppra) for the treatment of chorea in Huntington's diseaseTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center and Department of Neurology, University of South Florida, Tampa, Florida 33612, USA
Mov Disord 21:1998-2001. 2006..6 +/- 26.7 at endpoint; P = 0.24). Somnolence contributed to a 33% drop-out rate, and 3 patients developed Parkinsonism. Results of this open label study suggest that LEV may be efficacious in reducing chorea in HD patients...
Pregabalin (Lyrica) in the treatment of essential tremorTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, Department of Neurology, Neuroscience Program, University of South Florida, Tampa, Florida 33612, USA
Mov Disord 22:139-41. 2007..Both patients also reported moderate reduction in tremor on the Clinical Global Impression Scale, and Fahn-Tolosa-Marin Part I scores were markedly improved...
A double-blind placebo-controlled trial of zonisamide (zonegran) in the treatment of essential tremorTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida, Tampa, Florida 33612, USA
Mov Disord 22:279-82. 2007..ZNS did not provide significant improvements in clinical rating scales at study endpoint compared to placebo and was only modestly well tolerated. ZNS was effective in reducing tremor amplitude as measured by accelerometry...
Treatment of ataxia and imbalance with varenicline (chantix): report of 2 patients with spinocerebellar ataxia (types 3 and 14)Theresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, Department of Neurology, University of South Florida, Tampa, FL 34677, USA
Clin Neuropharmacol 31:363-5. 2008..Two patients with spinocerebellar ataxia (types 3 and 14) experienced marked improvement in their cerebellar symptoms shortly after taking varenicline (Chantix)...
Advances in the pharmacologic management of early Parkinson diseaseRobert A Hauser
Department of Neurology, Parkinson s Disease and Movement Disorders Center, University of South Florida and Tampa General Healthcare, Tampa, Florida 33606, USA
Neurologist 13:126-32. 2007..However, the disease continues to progress, and the long-term use of levodopa is associated with the development of motor fluctuations and dyskinesias...
Clinical trials aimed at detecting neuroprotection in Parkinson's diseaseRobert A Hauser
Department of Neurology, University of South Florida, Tampa General Healthcare, Tampa, Florida, USA
Neurology 66:S58-68. 2006..Better methods of assessing putative neuroprotection in PD are needed...
Chorea as a side effect of gabapentin (Neurontin) in a patient with complex regional pain syndrome Type 1Theresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, NPF Center of Excellence, University of South Florida, Tampa, FL, USA
Clin Rheumatol 27:389-90. 2008..The chorea lasted for a year and resolved completely within 2 weeks of discontinuing gabapentin...
Fentanyl-induced bradykinesia and rigidity after deep brain stimulation in a patient with Parkinson diseaseTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, Department of Neurology, University of South Florida, Tampa, 33612, USA
Clin Neuropharmacol 32:48-50. 2009..The severe bradykinesia and rigidity persisted despite reactivation of the deep brain stimulator and immediate reinstitution of Parkinson disease medications, but resolved completely several hours after discontinuation of fentanyl...
Topiramate-induced psychosis in patients with essential tremor: report of 2 casesTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida, Tampa, 33612, USA
Clin Neuropharmacol 29:168-9. 2006..All adverse symptoms resolved several days after topiramate was discontinued...
The controversy concerning plasma homocysteine in Parkinson disease patients treated with levodopa alone or with entacapone: effects of vitamin statusTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida, Tampa, 33612, USA
Clin Neuropharmacol 29:106-11. 2006..In patients with low or low-normal folate levels, levodopa administration is associated with a greater increase in homocysteine and concomitant entacapone administration is associated with a greater reduction in homocysteine...
Management of essential tremorTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center and Department of Neurology, University of South Florida, Harborside Medical Tower, 4 Columbia Drive, Suite 410, Tampa, FL 33606, USA
Curr Neurol Neurosci Rep 2:324-30. 2002..In patients with medically refractory tremor, alternative therapies, including surgery or injections of botulinum toxin, may be considered...
Clozapine withdrawal symptoms in a Parkinson's disease patientTheresa A Zesiewicz
Department of Neurology, Parkinson s Disease and Movement Disorders Center, University of South Florida and Tampa General Healthcare, Tampa, Florida 33606, USA
Mov Disord 17:1365-7. 2002..Clozapine should be gradually withdrawn over a period of 1 to 2 weeks when possible, and abruptly discontinued only when necessary...
Essential tremor. Epidemiology, diagnosis, and treatmentKelly L Sullivan
Department of Neurology, Parkinson's Disease and Movement Disorders Center, Tampa General Hospital Healthcare, University of South Florida, Tampa, Florida 33612, USA
Neurologist 10:250-8. 2004..Additional studies are also needed to determine the best treatment of head and voice tremor with pharmacologic and surgical interventions. With proper treatment, tremor is sufficiently reduced in the majority of patients...
Substantial improvement in a Meige's syndrome patient with levetiracetam treatmentTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida, Tampa, Florida, USA
Mov Disord 19:1518-21. 2004..This report and data from an animal model of paroxysmal dystonia suggest that LEV might be helpful in the treatment of dystonia...
Open-label pilot study of levetiracetam (Keppra) for the treatment of levodopa-induced dyskinesias in Parkinson's diseaseTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida, Tampa, Florida 336112, USA
Mov Disord 20:1205-9. 2005..There was a 56% dropout rate, mostly due to somnolence. In PD patients who experienced peak-dose dyskinesia for at least 25% of the awake day, LEV significantly improved on time without dyskinesia or with nontroublesome dyskinesia...
Levetiracetam-induced parkinsonism in a Huntington disease patientTheresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center, NPF Centers of Experience, Department of Neurology, University of South Florida Tampa, Florida 33612, USA
Clin Neuropharmacol 28:188-90. 2005..Symptoms consisted of resting tremor, rigidity, increased dystonia, and gait difficulty. Side effects from levetiracetam resolved completely within 7 days of levetiracetam discontinuation, and chorea returned to baseline...
Tegaserod (Zelnorm) for the treatment of constipation in Parkinson's diseaseKelly L Sullivan
Parkinson s Disease and Movement Disorders Center, NPF Center of Excellence, University of South Florida, Tampa, Florida 33612, USA
Mov Disord 21:115-6. 2006..There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS)...
Social Security Disability Insurance (SSDI) in Parkinson's diseaseT A Zesiewicz
Parkinson s Disease and Movement Disorders Center, University of South Florida, Tampa, FL 33612, USA
Disabil Rehabil 29:1934-6. 2007..We performed a descriptive pilot study that examined PD patients' experience with SSDI...
Deep brain stimulation of the ventral intermediate nucleus of the thalamus in medically refractory orthostatic tremor: preliminary observationsAlberto J Espay
Department of Neurology, The Neuroscience Institute, Movement Disorders Center, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
Mov Disord 23:2357-62. 2008..Further efficacy studies on chronic stimulation to disrupt the abnormal oscillatory activity in this disorder are warranted...
Phenomenology and treatment of tremor disordersT A Zesiewicz
Parkinson's Disease and Movement Disorders Center, Department of Neurology, Department of Pharmacology and Experimental Therapeutics, University of South Florida, Tampa, Florida, USA
Neurol Clin 19:651-80, vii. 2001..Accurate diagnosis is a critical factor in predicting the natural history and response to treatment...
Neurosurgery for Parkinson's diseaseT A Zesiewicz
Parkinson's Disease and Movement Disorders Center, Department of Neurology, University of South Florida, Tampa 33606, USA
Semin Neurol 21:91-101. 2001..This chapter reviews the history of surgical procedures for PD, describes current procedures, and offers a look into the future of neurosurgical options for PD...
Practice parameter: therapies for essential tremor: report of the Quality Standards Subcommittee of the American Academy of NeurologyT A Zesiewicz
Department of Neurology, Parkinson's Disease and Movement Disorders Center, University of South Florida, Tampa, USA
Neurology 64:2008-20. 2005..Additional prospective, double-blind, placebo-controlled trials are needed to better determine the efficacy and side effects of pharmacologic and surgical treatments of ET...
Chorea in a patient with cerebral palsy: treatment with levetiracetamMaria V Recio
Department of Neurology, University of South Florida, Tampa, FL 33612, USA
Mov Disord 20:762-4. 2005..We report on the case of an adult cerebral palsy patient who developed severe chorea coincident with a febrile illness from a nonstreptococcal infection. The chorea improved markedly with the use of levetiracetam (LEV, Keppra)...
Heart failure in Parkinson's disease: analysis of the United States medicare current beneficiary surveyT A Zesiewicz
Department of Neurology, University of South Florida, 12901 Bruce B. Downs Blvd MDC 55, Tampa, FL 33612, USA
Parkinsonism Relat Disord 10:417-20. 2004..CONCLUSIONS: In this cross-sectional study of a national Medicare database, heart failure occurred twice as frequently in elderly PD patients as in non-PD patients. Prospective studies are warranted to verify these findings...
Use of nutritional supplements in Parkinson's disease patientsSummer C Wolfrath
Parkinson's Disease and Movement Disorders Center, NPF Center of Excellence, and Department of Neurology, College of Medicine, University of South Florida, Tampa, Florida, USA
Mov Disord 21:1098-101. 2006..Greater awareness of nutritional supplement use in PD patients is warranted to avoid potentially harmful effects and drug interactions...
Sleep attacks and dopamine agonists for Parkinson's disease: what is currently known?Theresa A Zesiewicz
Parkinson s Disease and Movement Disorders Center and Department of Neurology, University of South Florida, Tampa General Healthcare, Tampa, Florida 33606, USA
CNS Drugs 17:593-600. 2003..Patients with Parkinson's disease and caregivers should be informed about the risk of sleepiness and sleep attacks associated with dopaminergic medications and the potential implications for driving safety...
Levetiracetam for the treatment of generalized dystoniaKelly L Sullivan
Parkinson's Disease and Movement Disorders Center, University of South Florida, Tampa, FL 33612, USA
Parkinsonism Relat Disord 11:469-71. 2005..Improvements were noted in blepharospasm, cervical, and truncal dystonia. The patient has been on LEV for a total of 20 weeks, and has experienced sustained improvement of symptoms...
Quantitative analysis of tremors in weldersJuan Sanchez-Ramos
College of Medicine, University of South Florida, Tampa, FL 33612, USA
Int J Environ Res Public Health 8:1478-90. 2011..Workers chronically exposed to manganese in welding fumes may develop an extra-pyramidal syndrome with postural and action tremors...
Levetiracetam for stiff-person syndrome: report of 2 patientsW Reed Shimberg
Parkinson s Disease and Movement Disorders Center, NPF Center of Excellence, Tampa, Florida, USA
Clin Neuropharmacol 31:301-2. 2008..We report 2 patients with stiff-person syndrome whose spasms were greatly relieved by levetiracetam (Keppra)...
Treatment of chorea with levetiracetamTheresa A Zesiewicz
Eur J Clin Pharmacol 62:87. 2006
Zonisamide-induced mania in an essential tremor patientKelly L Sullivan
J Clin Psychopharmacol 26:439-40. 2006
Low-dose topiramate (topamax) in the treatment of essential tremorTheresa A Zesiewicz
Clin Neuropharmacol 30:247-8. 2007
Tiagabine and exacerbation of essential tremorTheresa A Zesiewicz
Mov Disord 22:2132-3. 2007
Chorea induced by lamotrigineTheresa A Zesiewicz
J Child Neurol 21:357; author reply 357-8. 2006
Levetiracetam for the treatment of essential tremorKelly L Sullivan
Mov Disord 20:640. 2005
Vascular hemichorea/hemiballismus and topiramateTheresa A Zesiewicz
Mov Disord 21:581; author reply 582. 2006
Prevalence and treatment of non-motor symptoms in Parkinson's diseaseKelly L Sullivan
Parkinsonism Relat Disord 13:545. 2007
Delayed thalamic intracranial hemorrhage in an essential tremor patient following deep brain stimulationTheresa A Zesiewicz
Eur Neurol 59:187-9. 2008
